List of works - Rastislav Jendzelovský

3,6-bis(3-alkylguanidino)acridines as DNA-intercalating antitumor agents

scientific article published on 23 September 2012

Antitumor effect of the combination of manumycin A and Immodin is associated with antiplatelet activity and increased granulocyte tumor infiltration in a 4T1 breast tumor model.

scientific article published on 22 November 2016

Atranorin, a Secondary Metabolite of Lichens, Exhibited Anxiolytic/Antidepressant Activity in Wistar Rats

scientific article published on 11 November 2022

Drug efflux transporters, MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells.

scientific article published on 23 October 2009

Drug membrane transporters and CYP3A4 are affected by hypericin, hyperforin or aristoforin in colon adenocarcinoma cells

scientific article published on 8 April 2016

Flow cytometric determination of 5-bromo-2'-deoxyuridine pharmacokinetics in blood serum after intraperitoneal administration to rats and mice.

scientific article published on 25 July 2014

Fluorinated 3,6,9-trisubstituted acridine derivatives as DNA interacting agents and topoisomerase inhibitors with A549 antiproliferative activity

scientific article published on 23 October 2019

Histone deacetylase inhibitors potentiate photodynamic therapy in colon cancer cells marked by chromatin-mediated epigenetic regulation of CDKN1A.

scientific article

Hypericin affects cancer side populations via competitive inhibition of BCRP.

scientific article published on 20 February 2018

In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers

scientific article published on 01 December 2019

Inhibition of DNA topoisomerases I and II and growth inhibition of HL-60 cells by novel acridine-based compounds.

scientific article published on 8 May 2015

Inhibition of GSK-3β reverses the pro-apoptotic effect of proadifen (SKF-525A) in HT-29 colon adenocarcinoma cells.

scientific article published on 7 June 2012

Lichen secondary metabolites are responsible for induction of apoptosis in HT-29 and A2780 human cancer cell lines.

scientific article published on 21 January 2012

Lower sensitivity of FHC fetal colon epithelial cells to photodynamic therapy compared to HT-29 colon adenocarcinoma cells despite higher intracellular accumulation of hypericin ⬇️

scientific article published on February 4, 2011

New spiro tria(thia)zolidine-acridines as topoisomerase inhibitors, DNA binders and cytostatic compounds

scientific article published on 6 February 2016

Novel Insights into the Effect of Hyperforin and Photodynamic Therapy with Hypericin on Chosen Angiogenic Factors in Colorectal Micro-Tumors Created on Chorioallantoic Membrane

scientific article published on 19 June 2019

PUFAs enhance oxidative stress and apoptosis in tumour cells exposed to hypericin-mediated PDT.

scientific article published on 12 August 2010

Peroral administration of 5-bromo-2-deoxyuridine in drinking water is not a reliable method for labeling proliferating S-phase cells in rats.

scientific article published on 2 June 2015

Potency of non-steroidal anti-inflammatory drugs in chemotherapy.

scientific article

Potentiality, Limitations, and Consequences of Different Experimental Models to Improve Photodynamic Therapy for Cancer Treatment in Relation to Antiangiogenic Mechanism

scientific article published on 30 July 2020

Procedure for improved cleaning of FACSAria cuvette flow cell.

scientific article

Resveratrol enhances the chemopreventive effect of celecoxib in chemically induced breast cancer in rats

scientific article published on November 2014

Tacrine derivatives as dual topoisomerase I and II catalytic inhibitors.

scientific article

The pro-apoptotic and anti-invasive effects of hypericin-mediated photodynamic therapy are enhanced by hyperforin or aristoforin in HT-29 colon adenocarcinoma cells ⬇️

scientific article published on September 18, 2012

The role of p53 in the efficiency of photodynamic therapy with hypericin and subsequent long-term survival of colon cancer cells.

scientific article published on 10 September 2009

Variable responses of different human cancer cells to the lichen compounds parietin, atranorin, usnic acid and gyrophoric acid ⬇️

scientific article published on September 17, 2010

YM155, a small molecule inhibitor of survivin expression, sensitizes cancer cells to hypericin-mediated photodynamic therapy.

scientific article published on 31 May 2016

List of works by Rastislav Jendzelovský

3,6-bis(3-alkylguanidino)acridines as DNA-intercalating antitumor agents

Antitumor effect of the combination of manumycin A and Immodin is associated with antiplatelet activity and increased granulocyte tumor infiltration in a 4T1 breast tumor model.

Atranorin, a Secondary Metabolite of Lichens, Exhibited Anxiolytic/Antidepressant Activity in Wistar Rats

Drug efflux transporters, MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells.

Drug membrane transporters and CYP3A4 are affected by hypericin, hyperforin or aristoforin in colon adenocarcinoma cells

Flow cytometric determination of 5-bromo-2'-deoxyuridine pharmacokinetics in blood serum after intraperitoneal administration to rats and mice.

Fluorinated 3,6,9-trisubstituted acridine derivatives as DNA interacting agents and topoisomerase inhibitors with A549 antiproliferative activity

Histone deacetylase inhibitors potentiate photodynamic therapy in colon cancer cells marked by chromatin-mediated epigenetic regulation of CDKN1A.

Hypericin affects cancer side populations via competitive inhibition of BCRP.

In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers

Inhibition of DNA topoisomerases I and II and growth inhibition of HL-60 cells by novel acridine-based compounds.

Inhibition of GSK-3β reverses the pro-apoptotic effect of proadifen (SKF-525A) in HT-29 colon adenocarcinoma cells.

Lichen secondary metabolites are responsible for induction of apoptosis in HT-29 and A2780 human cancer cell lines.

Lower sensitivity of FHC fetal colon epithelial cells to photodynamic therapy compared to HT-29 colon adenocarcinoma cells despite higher intracellular accumulation of hypericin ⬇️

New spiro tria(thia)zolidine-acridines as topoisomerase inhibitors, DNA binders and cytostatic compounds

Novel Insights into the Effect of Hyperforin and Photodynamic Therapy with Hypericin on Chosen Angiogenic Factors in Colorectal Micro-Tumors Created on Chorioallantoic Membrane

PUFAs enhance oxidative stress and apoptosis in tumour cells exposed to hypericin-mediated PDT.

Peroral administration of 5-bromo-2-deoxyuridine in drinking water is not a reliable method for labeling proliferating S-phase cells in rats.

Potency of non-steroidal anti-inflammatory drugs in chemotherapy.

Potentiality, Limitations, and Consequences of Different Experimental Models to Improve Photodynamic Therapy for Cancer Treatment in Relation to Antiangiogenic Mechanism

Procedure for improved cleaning of FACSAria cuvette flow cell.

Resveratrol enhances the chemopreventive effect of celecoxib in chemically induced breast cancer in rats

Tacrine derivatives as dual topoisomerase I and II catalytic inhibitors.

The pro-apoptotic and anti-invasive effects of hypericin-mediated photodynamic therapy are enhanced by hyperforin or aristoforin in HT-29 colon adenocarcinoma cells ⬇️

The role of p53 in the efficiency of photodynamic therapy with hypericin and subsequent long-term survival of colon cancer cells.

Variable responses of different human cancer cells to the lichen compounds parietin, atranorin, usnic acid and gyrophoric acid ⬇️

YM155, a small molecule inhibitor of survivin expression, sensitizes cancer cells to hypericin-mediated photodynamic therapy.