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List of works by Rasmus Jansson-Lofmark

A modeling approach for compounds affecting body composition

scientific article published on 25 October 2013

ADME: Assessing Pharmacokinetic-Pharmacodynamic Parameters of Oligonucleotides

scientific article published on 01 January 2019

Chiral Chromatographic Isolation on Milligram Scale of the Human African Trypanosomiasis Treatment d- and l-Eflornithine

scientific article published on 11 September 2020

Clinical safety, tolerability, pharmacokinetics and effects on urinary electrolyte excretion of AZD9977, a novel, selective mineralocorticoid receptor modulator

scientific article published on 21 February 2018

Comparative quantitative systems pharmacology modeling of anti-PCSK9 therapeutic modalities in hypercholesterolemia

scientific article published on 10 July 2019

Correlation of body weight and composition with hepatic activities of cytochrome P450 enzymes

scientific article published on 19 October 2020

Corrigendum to 'Drug metabolism and pharmacokinetic strategies for oligonucleotide- and mRNA-based drug development' Drug Discovery Today 23 (2018) 1733-1745

scientific article published on 07 December 2018

Determination of eflornithine enantiomers in plasma by precolumn derivatization with o-phthalaldehyde-N-acetyl-L-cysteine and liquid chromatography with UV detection.

scientific article

Does in vitro potency predict clinical efficacious concentrations?

scientific article published on 10 April 2020

Drug metabolism and pharmacokinetic strategies for oligonucleotide- and mRNA-based drug development

scientific article published on 28 May 2018

Enantiospecific reassessment of the pharmacokinetics and pharmacodynamics of oral eflornithine against late-stage Trypanosoma brucei gambiense sleeping sickness.

scientific article

Erratum: Publisher Correction: Mathematical model of hemodynamic mechanisms and consequences of glomerular hypertension in diabetic mice

scientific article published on 04 March 2019

Evaluation of pharmacokinetic and pharmacodynamic profiles of liposomes for the cell type-specific delivery of small molecule drugs

scientific article published on 25 July 2017

Feedback modeling of non-esterified fatty acids in rats after nicotinic acid infusions.

scientific article published on 4 November 2010

Identification of Mineralocorticoid Receptor Modulators with Low Impact on Electrolyte Homeostasis but Maintained Organ Protection

scientific article published on 30 January 2019

Improving the Accuracy of Predicted Human Pharmacokinetics: Lessons Learned from the AstraZeneca Drug Pipeline Over Two Decades

scientific article published on 28 April 2020

Inferring Half-Lives at the Effect Site of Oligonucleotide Drugs

scientific article published on 31 October 2018

Mathematical model of hemodynamic mechanisms and consequences of glomerular hypertension in diabetic mice

scientific article published on 10 December 2018

Model-based drug discovery: implementation and impact.

scientific article published on 29 May 2013

Population pharmacokinetic modeling and deconvolution of enantioselective absorption of eflornithine in the rat.

scientific article published on 10 January 2013

Preclinical pharmacology of AZD9977: A novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion.

scientific article published on 23 February 2018

Proteomics-informed prediction of rosuvastatin plasma profiles in patients with a wide range of body weight

scientific article published on 24 September 2020

Robust anti-obesity and metabolic effects of a dual GLP-1/glucagon receptor peptide agonist in rodents and non-human primates

scientific article

Targeted delivery of antisense oligonucleotides to pancreatic β-cells

scientific article published on 17 October 2018

The selective mineralocorticoid receptor modulator AZD9977 reveals differences in mineralocorticoid effects of aldosterone and fludrocortisone

scientific article published on 01 January 2019

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