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List of works by Izzy Jayasinghe

4D super-resolution microscopy with conventional fluorophores and single wavelength excitation in optically thick cells and tissues

scientific article

A Review of Barriers Women Face in Research Funding Processes in the UK

A correlative super-resolution protocol to visualise structural underpinnings of fast second-messenger signalling in primary cell types

scientific article published on 12 October 2020

A new twist in cardiac muscle: dislocated and helicoid arrangements of myofibrillar z-disks in mammalian ventricular myocytes.

scientific article published on 4 January 2010

Algorithmic corrections for localization microscopy with sCMOS cameras - characterisation of a computationally efficient localization approach. ⬇️

scientific article published in May 2017

Combining confocal and single molecule localisation microscopy: A correlative approach to multi-scale tissue imaging.

scientific article published on 24 March 2015

Comparison of the organization of T-tubules, sarcoplasmic reticulum and ryanodine receptors in rat and human ventricular myocardium

scientific article published on 01 May 2012

Correlative Single-Molecule Localization Microscopy and Confocal Microscopy.

scientific article published in January 2017

Examination of the subsarcolemmal tubular system of mammalian skeletal muscle fibers.

scientific article published on June 2013

Human skeletal muscle plasmalemma alters its structure to change its Ca2+-handling following heavy-load resistance exercise. ⬇️

scientific article published on 13 February 2017

Junctophilin-2 in the nanoscale organisation and functional signalling of ryanodine receptor clusters in cardiomyocytes ⬇️

scientific article published on 21 October 2016

Light-induced dark states of organic fluochromes enable 30 nm resolution imaging in standard media.

scientific article published on January 2009

Multi-scale approaches for the simulation of cardiac electrophysiology: I - Sub-cellular and stochastic calcium dynamics from cell to organ

scientific article published on 29 February 2020

Nanoscale analysis of ryanodine receptor clusters in dyadic couplings of rat cardiac myocytes

scientific article published on 20 December 2014

Observation of the molecular organization of calcium release sites in fast- and slow-twitch skeletal muscle with nanoscale imaging

scientific article published on October 2014

Optical single-channel resolution imaging of the ryanodine receptor distribution in rat cardiac myocytes

scientific article

Organization of ryanodine receptors, transverse tubules, and sodium-calcium exchanger in rat myocytes.

scientific article

Rab46 integrates Ca2+ and histamine signaling to regulate selective cargo release from Weibel-Palade bodies

scientific article published on 15 May 2019

Resolving the structural basis of cardiac excitation-contraction coupling ⬇️

2010 doctoral thesis by Izzy Jayasinghe at University of Auckland

Revealing T-Tubules in Striated Muscle with New Optical Super-Resolution Microscopy Techniquess ⬇️

scientific article published on 7 January 2015

Shining New Light on the Structural Determinants of Cardiac Couplon Function: Insights From Ten Years of Nanoscale Microscopy ⬇️

scientific article published on 22 October 2018

Super-resolution fluorescence imaging to study cardiac biophysics: α-actinin distribution and Z-disk topologies in optically thick cardiac tissue slices.

scientific article

Three-Dimensional and Chemical Mapping of Intracellular Signaling Nanodomains in Health and Disease with Enhanced Expansion Microscopy

article

Three-dimensional high-resolution imaging of cardiac proteins to construct models of intracellular Ca2+ signalling in rat ventricular myocytes.

scientific article published on 12 January 2009

Transverse tubule remodelling: a cellular pathology driven by both sides of the plasmalemma? ⬇️

scientific article published on 10 July 2017

True Molecular Scale Visualization of Variable Clustering Properties of Ryanodine Receptors. ⬇️

scientific article published in January 2018

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