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List of works by Cláudia Lobato da Silva

A Fully-Closed and Automated Hollow Fiber Bioreactor for Clinical-Grade Manufacturing of Human Mesenchymal Stem/Stromal Cells.

scientific article

A Stro-1(+) human universal stromal feeder layer to expand/maintain human bone marrow hematopoietic stem/progenitor cells in a serum-free culture system.

scientific article published in October 2006

A human stromal-based serum-free culture system supports the ex vivo expansion/maintenance of bone marrow and cord blood hematopoietic stem/progenitor cells

scientific article published in July 2005

A novel method for human hematopoietic stem/progenitor cell isolation from umbilical cord blood based on immunoaffinity aqueous two-phase partitioning

scientific article published on 21 August 2011

A xeno-free microcarrier-based stirred culture system for the scalable expansion of human mesenchymal stem/stromal cells isolated from bone marrow and adipose tissue.

scientific article published on 24 July 2015

A xenogeneic-free bioreactor system for the clinical-scale expansion of human mesenchymal stem/stromal cells

scientific article published on 04 February 2014

Acellular Urethra Bioscaffold: Decellularization of Whole Urethras for Tissue Engineering Applications

scientific article

Addressing the Manufacturing Challenges of Cell-Based Therapies

scientific article published on 01 January 2020

An appraisal of human mitochondrial DNA instability: new insights into the role of non-canonical DNA structures and sequence motifs.

scientific article

Biomimetic matrices for rapidly forming mineralized bone tissue based on stem cell-mediated osteogenesis

scientific article published in Scientific Reports

Bioreactor design for clinical-grade expansion of stem cells.

scientific article published on 26 April 2013

Chondrogenic differentiation of mesenchymal stem/stromal cells on 3D porous poly (ε-caprolactone) scaffolds: Effects of material alkaline treatment and chondroitin sulfate supplementation

scientific article published on 25 February 2020

Clinical-Grade Manufacturing of Therapeutic Human Mesenchymal Stem/Stromal Cells in Microcarrier-Based Culture Systems.

scientific article published in January 2016

Co-culture cell-derived extracellular matrix loaded electrospun microfibrous scaffolds for bone tissue engineering

scientific article published on 30 January 2019

Concise review: Genomic instability in human stem cells: current status and future challenges.

scientific article

Cultured cell-derived extracellular matrices to enhance the osteogenic differentiation and angiogenic properties of human mesenchymal stem/stromal cells

scientific article published on 10 July 2019

Developing a co-culture system for effective megakaryo/thrombopoiesis from umbilical cord blood hematopoietic stem/progenitor cells

scientific article

Differences amid bone marrow and cord blood hematopoietic stem/progenitor cell division kinetics

scientific article published on July 2009

Different stages of pluripotency determine distinct patterns of proliferation, metabolism, and lineage commitment of embryonic stem cells under hypoxia.

scientific article published on 22 April 2010

Differentiation of human umbilical cord matrix mesenchymal stem cells into neural-like progenitor cells and maturation into an oligodendroglial-like lineage

scientific article

Dynamic cell-cell interactions between cord blood haematopoietic progenitors and the cellular niche are essential for the expansion of CD34+, CD34+CD38- and early lymphoid CD7+ cells.

scientific article published in February 2010

Engineering of Human Mesenchymal Stem/Stromal Cells with Vascular Endothelial Growth Factor-Encoding Minicircles for Angiogenic Ex Vivo Gene Therapy

scientific article published on 13 November 2018

Evaluation of gene delivery strategies to efficiently overexpress functional HLA-G on human bone marrow stromal cells

scientific article published on September 2014

Ex vivo expansion of cord blood haematopoietic stem/progenitor cells under physiological oxygen tensions: clear-cut effects on cell proliferation, differentiation and metabolism.

scientific article published on 17 April 2013

Ex vivo expansion of human mesenchymal stem cells: a more effective cell proliferation kinetics and metabolism under hypoxia.

scientific article published in April 2010

Extracellular matrix microarrays to study inductive signaling for endoderm specification

scientific article published on 12 February 2016

Extruded Bioreactor Perfusion Culture Supports the Chondrogenic Differentiation of Human Mesenchymal Stem/Stromal Cells in 3D Porous Poly(ɛ-Caprolactone) Scaffolds

scientific article published on 21 October 2019

Gelatin porous scaffolds fabricated using a modified gas foaming technique: characterisation and cytotoxicity assessment.

scientific article

Gene delivery to human bone marrow mesenchymal stem cells by microporation.

scientific article published on 16 November 2010

Hematopoietic Niche - Exploring Biomimetic Cues to Improve the Functionality of Hematopoietic Stem/Progenitor Cells

scientific article published on 27 November 2017

Human mesenchymal stem cell expression program upon extended ex-vivo cultivation, as revealed by 2-DE-based quantitative proteomics.

scientific article

Human mesenchymal stem cells from the umbilical cord matrix: successful isolation and ex vivo expansion using serum-/xeno-free culture media.

scientific article

Impact of hypoxia and long-term cultivation on the genomic stability and mitochondrial performance of ex vivo expanded human stem/stromal cells

scientific article published on 23 July 2012

In vitro assessment of three dimensional dense chitosan-based structures to be used as bioabsorbable implants.

scientific article published on 28 September 2014

Initial CD34+ cell-enrichment of cord blood determines hematopoietic stem/progenitor cell yield upon ex vivo expansion.

scientific article published in July 2011

Integrated culture platform based on a human platelet lysate supplement for the isolation and scalable manufacturing of umbilical cord matrix-derived mesenchymal stem/stromal cells.

scientific article published on 22 July 2016

Intracoronary Delivery of Human Mesenchymal/Stromal Stem Cells: Insights from Coronary Microcirculation Invasive Assessment in a Swine Model

scientific article published on 19 October 2015

Kinetic and metabolic analysis of mouse embryonic stem cell expansion under serum-free conditions.

scientific article

Large-scale expansion of mouse embryonic stem cells on microcarriers.

scientific article published in January 2011

Loss and rescue of osteocalcin and osteopontin modulate osteogenic and angiogenic features of mesenchymal stem/stromal cells

scientific article published on 11 March 2020

Magnetoresistive chip cytometer.

scientific article published on 12 May 2011

Maximizing the ex vivo expansion of human mesenchymal stem cells using a microcarrier-based stirred culture system

article

Mesenchymal stem cells from umbilical cord matrix, adipose tissue and bone marrow exhibit different capability to suppress peripheral blood B, natural killer and T cells.

scientific article published on 15 October 2013

Microcarrier expansion of mouse embryonic stem cell-derived neural stem cells in stirred bioreactors.

scientific article

Mobile-Phase Modulators as Salt Tolerance Enhancers in Phenylboronate Chromatography: Thermodynamic Evaluation of the Mechanisms Underlying the Adsorption of Monoclonal Antibodies

scientific article published on 13 August 2019

Modulation of the in vitro angiogenic potential of human mesenchymal stromal cells from different tissue sources

scientific article published on 09 February 2020

Monitoring the ex-vivo expansion of human mesenchymal stem/stromal cells in xeno-free microcarrier-based reactor systems by MIR spectroscopy

scientific article published on 23 December 2015

Oxazoline-based antimicrobial oligomers: synthesis by CROP using supercritical CO2.

scientific article

Polyhydroxyalkanoates: waste glycerol upgrade into electrospun fibrous scaffolds for stem cells culture

scientific article published on 14 May 2014

Proliferation extent of CD34+ cells as a key parameter to maximize megakaryocytic differentiation of umbilical cord blood-derived hematopoietic stem/progenitor cells in a two-stage culture protocol

scientific article published on 16 July 2014

Scalable ex vivo expansion of human mesenchymal stem/stromal cells in microcarrier-based stirred culture systems.

scientific article

Scalable microcarrier-based manufacturing of mesenchymal stem/stromal cells.

scientific article published on 12 August 2016

Scale-up of mouse embryonic stem cell expansion in stirred bioreactors.

scientific article published on 25 July 2011

Scaling up the ex vivo expansion of human circulating CD34(+)progenitor cells with upregulation of angiogenic and anti-inflammatory potential.

scientific article

Separation technologies for stem cell bioprocessing.

scientific article published on 22 August 2012

Stem Cell Bioprocessing and Manufacturing

scientific article published on 31 July 2020

Stem cell bioengineering strategies to widen the therapeutic applications of haematopoietic stem/progenitor cells from umbilical cord blood.

scientific article published on 08 April 2013

Stirred tank bioreactor culture combined with serum-/xenogeneic-free culture medium enables an efficient expansion of umbilical cord-derived mesenchymal stem/stromal cells.

scientific article published on 11 May 2016

Successful isolation and ex vivo expansion of human mesenchymal stem/stromal cells obtained from different synovial tissue-derived (biopsy) samples

scientific article published on 26 August 2018

Synergistic effect of extracellularly supplemented osteopontin and osteocalcin on stem cell proliferation, osteogenic differentiation, and angiogenic properties

scientific article published on 25 October 2018

Systematic delineation of optimal cytokine concentrations to expand hematopoietic stem/progenitor cells in co-culture with mesenchymal stem cells

scientific article published on 27 April 2010

Thermodynamics of the adsorption of monoclonal antibodies in phenylboronate chromatography: Affinity versus multimodal interactions

scientific article published on 17 July 2018

Three-Dimensional Co-culture of Human Hematopoietic Stem/Progenitor Cells and Mesenchymal Stem/Stromal Cells in a Biomimetic Hematopoietic Niche Microenvironment

article

Tridimensional configurations of human mesenchymal stem/stromal cells to enhance cell paracrine potential towards wound healing processes.

scientific article

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