List of works by Masahiro Yasunaga

Antibody fragment-conjugated polymeric micelles incorporating platinum drugs for targeted therapy of pancreatic cancer

scientific article

Antitumor effect of NK012, a 7-ethyl-10-hydroxycamptothecin-incorporating polymeric micelle, on U87MG orthotopic glioblastoma in mice compared with irinotecan hydrochloride in combination with bevacizumab.

scientific article

Antitumor effect of antitissue factor antibody-MMAE conjugate in human pancreatic tumor xenografts

scientific article published on 09 March 2015

Antitumour activity of NK012, SN-38-incorporating polymeric micelles, in hypovascular orthotopic pancreatic tumour.

scientific article published on 16 December 2009

Anti‑tissue factor antibody‑mediated immuno‑SPECT imaging of tissue factor expression in mouse models of pancreatic cancer

scientific article published on 14 February 2019

Cancer-stroma targeting therapy by cytotoxic immunoconjugate bound to the collagen 4 network in the tumor tissue.

scientific article published on 4 August 2011

Chemotherapy payload of anti-insoluble fibrin antibody-drug conjugate is released specifically upon binding to fibrin

scientific article published in Scientific Reports

Collagen type I induces EGFR-TKI resistance in EGFR-mutated cancer cells via mTOR activation through Akt-independent pathway.

scientific article published on 27 April 2018

Detailed distribution of NK012, an SN-38-incorporating micelle, in the liver and its potent antitumor effects in mice bearing liver metastases.

scientific article published on 31 August 2010

Development of ADCs Using Molecular Imaging

scientific article published in January 2017

Development of Antibody-Drug Conjugates Using DDS and Molecular Imaging.

scientific article published on 17 September 2017

Discovery of an uncovered region in fibrin clots and its clinical significance.

scientific article published on January 2013

Effect of combined treatment with micelle-incorporated cisplatin (NC-6004) and S-1 on human gastric cancer xenografts.

scientific article

Effect of combined treatment with the epirubicin-incorporating micelles (NC-6300) and 1,2-diaminocyclohexane platinum (II)-incorporating micelles (NC-4016) on a human gastric cancer model

scientific article published on 18 December 2013

Enhanced antitumor effect of anti-tissue factor antibody-conjugated epirubicin-incorporating micelles in xenograft models.

scientific article published on 23 March 2015

Feasibility study of the Fab fragment of a monoclonal antibody against tissue factor as a diagnostic tool

scientific article published on 19 October 2015

Imaging mass spectrometry for the precise design of antibody-drug conjugates.

scientific article

Immunoregulation by IL-7R-targeting antibody-drug conjugates: overcoming steroid-resistance in cancer and autoimmune disease.

scientific article published on 6 September 2017

Influence of the dissociation rate constant on the intra-tumor distribution of antibody-drug conjugate against tissue factor

scientific article published on 12 June 2018

Making the in-vitro model closer to actual B lymphopoiesis in the bone marrow ⬇️

scientific article published on June 1, 1995

Mechanism of action of a T cell-dependent bispecific antibody as a breakthrough immunotherapy against refractory colorectal cancer with an oncogenic mutation

scientific article published on 14 July 2020

MicroRNA Expression Profiling of Exfoliated Colonocytes Isolated from Feces for Colorectal Cancer Screening ⬇️

scientific article published on October 19, 2010

Molecular imaging using an anti-human tissue factor monoclonal antibody in an orthotopic glioma xenograft model

scientific article published on 26 September 2017

NC-6300, an epirubicin-incorporating micelle, extends the antitumor effect and reduces the cardiotoxicity of epirubicin.

scientific article published on 19 April 2013

Near-infrared photoimmunotherapy of pancreatic cancer using an indocyanine green-labeled anti-tissue factor antibody

scientific article published on 01 December 2018

New concept of cytotoxic immunoconjugate therapy targeting cancer-induced fibrin clots

scientific article published on 09 May 2011

Preclinical efficacy of Sym004, novel anti-EGFR antibody mixture, in esophageal squamous cell carcinoma cell lines.

scientific article published on 26 December 2016

Preparation and characterization of anti-tissue factor single-chain variable fragment antibody for cancer diagnosis.

scientific article

Protection from contamination by <sup>211</sup>At, an enigmatic but promising alpha-particle-emitting radionuclide

publication published on 06 June 2022

Role of SLC6A6 in promoting the survival and multidrug resistance of colorectal cancer.

scientific article published on 30 April 2014

Significant antitumor effect of an antibody against TMEM180, a new colorectal cancer-specific molecule

scientific article published on 04 January 2019

Synergistic antitumor activity of the SN-38-incorporating polymeric micelles NK012 with S-1 in a mouse model of non-small cell lung cancer.

scientific article

The inhibition of pancreatic cancer invasion-metastasis cascade in both cellular signal and blood coagulation cascade of tissue factor by its neutralisation antibody.

scientific article published on 27 May 2011

The significance of microscopic mass spectrometry with high resolution in the visualisation of drug distribution

scientific article

Tumour imaging by the detection of fibrin clots in tumour stroma using an anti-fibrin Fab fragment.

scientific article published on 24 March 2016

U3-1402, a Novel HER3-Targeting Antibody-Drug Conjugate, for the Treatment of Colorectal Cancer

scientific article published on 08 August 2019

Utility of epirubicin-incorporating micelles tagged with anti-tissue factor antibody clone with no anticoagulant effect.

scientific article published on 17 December 2015

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