List of works - Adam E Handel

Ageing compromises mouse thymus function and remodels epithelial cell differentiation

scientific article published on 25 August 2020

An Updated Meta-Analysis of Risk of Multiple Sclerosis following Infectious Mononucleosis ⬇️

scientific article published on September 1, 2010

Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics.

scientific article published on 5 January 2016

Bioinformatics Analysis of Estrogen-Responsive Genes

scientific article published on January 2016

Clinical features which predict neuronal surface autoantibodies in new-onset focal epilepsy: implications for immunotherapies

scientific article published on 20 November 2020

Comment on "Epigenetic reduction in invariant NKT cells following in utero vitamin D deficiency in mice"

scientific article published on 01 April 2011

Comment on "Gender differences in 1,25 dihydroxyvitamin D3 immunomodulatory effects in multiple sclerosis patients and healthy subjects"

scientific article published on 01 January 2011

Comment on "Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells"

scientific article published on 01 November 2019

Concealed effects of gene-environment interactions in genome-wide association

scientific article published on 9 September 2011

Contribution of genetic, epigenetic and transcriptomic differences to twin discordance in multiple sclerosis.

scientific article

DNase hypersensitive sites and association with multiple sclerosis

scientific article published on 02 October 2013

Developmental dynamics of the neural crest-mesenchymal axis in creating the thymic microenvironment

scientific article published on 13 May 2022

EBNA2 binds to genomic intervals associated with multiple sclerosis and overlaps with vitamin D receptor occupancy.

scientific article published on 8 April 2015

Epigenetic mechanisms in multiple sclerosis and the major histocompatibility complex (MHC).

scientific article published on March 2011

Epigenetics: molecular mechanisms and implications for disease.

scientific article

Estrogen-vitamin D interaction in multiple sclerosis

scientific article published on 05 November 2010

FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency

scientific article published on 03 December 2021

Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells

scientific article

GPC5 and lung cancer in multiple sclerosis

scientific article published on 01 August 2010

Genetic and environmental factors and the distribution of multiple sclerosis in Europe

scientific article published on 22 March 2010

Geography of hospital admissions for multiple sclerosis in England and comparison with the geography of hospital admissions for infectious mononucleosis: a descriptive study ⬇️

scientific article published on January 6, 2011

HLA-DRB1 confers increased risk of pediatric-onset MS in children with acquired demyelination ⬇️

scientific article published on February 2, 2011

Heterogeneity in multiple sclerosis: scratching the surface of a complex disease.

scientific article

High reprint orders in medical journals and pharmaceutical industry funding: case-control study

scientific article (publication date: 28 June 2012)

Indispensable epigenetic control of thymic epithelial cell development and function by polycomb repressive complex 2

scientific article published on 24 June 2021

Inequities in advice on vitamin D?

scientific article published on 23 January 2011

Most brain disease-associated and eQTL haplotypes are not located within transcription factor DNase-seq footprints in brain

scientific article published on 26 October 2016

Multiple sclerosis and lung cancer: an unexpected inverse association.

scientific article published on 20 May 2010

Multiple sclerosis and risk of cancer: a meta-analysis

scientific article published on 19 August 2010

Next-generation sequencing in understanding complex neurological disease

scientific article published on February 2013

No evidence for an effect of DNA methylation on multiple sclerosis severity at HLA-DRB1*15 or HLA-DRB5

article

Of mice and men: experimental autoimmune encephalitis and multiple sclerosis.

scientific article published on 21 March 2011

Rare variants in the CYP27B1 gene are associated with multiple sclerosis.

scientific article

Relationship of UV exposure to prevalence of multiple sclerosis in England ⬇️

scientific article published on April 19, 2011

Revisiting the T-cell receptor alpha/delta locus and possible associations with multiple sclerosis.

scientific article published on 27 January 2011

Season of birth and anorexia nervosa ⬇️

scientific article published on March 17, 2011

Seasonality of admissions with multiple sclerosis in Scotland.

scientific article published on 29 December 2010

Smoking and multiple sclerosis: a matter of global importance

scientific article published on 07 December 2011

Targeted RNA sequencing enhances gene expression profiling of ultra-low input samples

scientific article published on 28 June 2020

The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function

scientific article published on 03 June 2021

The contribution of thymic tolerance to central nervous system autoimmunity

scientific article published on 27 October 2020

The crystal structure of human forkhead box N1 in complex with DNA reveals the structural basis for forkhead box family specificity

scientific article published on 30 December 2019

The epidemiology of multiple sclerosis in Scotland: inferences from hospital admissions.

scientific article

The potential role of major histocompatibility complex class I in schizophrenia

scientific article published on 01 October 2010

The questionable effectiveness of sunscreen

scientific article published on 01 July 2010

Tuberculosis and diabetes mellitus: is vitamin D the missing link?

scientific article published on 01 September 2010

Variants in ST8SIA1 do not play a major role in susceptibility to multiple sclerosis in Canadian families

article

Visceral obesity and brain volume

scientific article published on 01 November 2010

Vitamin D and multiple sclerosis hospital admissions in Scotland.

scientific article published on 29 June 2011

Vitamin D and multiple sclerosis: an interaction between genes and environment

scientific article published on 01 January 2012

Vitamin D receptor ChIP-seq in primary CD4+ cells: relationship to serum 25-hydroxyvitamin D levels and autoimmune disease

scientific article

List of works by Adam E Handel

Ageing compromises mouse thymus function and remodels epithelial cell differentiation

An Updated Meta-Analysis of Risk of Multiple Sclerosis following Infectious Mononucleosis ⬇️

Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics.

Bioinformatics Analysis of Estrogen-Responsive Genes

Clinical features which predict neuronal surface autoantibodies in new-onset focal epilepsy: implications for immunotherapies

Comment on "Epigenetic reduction in invariant NKT cells following in utero vitamin D deficiency in mice"

Comment on "Gender differences in 1,25 dihydroxyvitamin D3 immunomodulatory effects in multiple sclerosis patients and healthy subjects"

Comment on "Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells"

Concealed effects of gene-environment interactions in genome-wide association

Contribution of genetic, epigenetic and transcriptomic differences to twin discordance in multiple sclerosis.

DNase hypersensitive sites and association with multiple sclerosis

Developmental dynamics of the neural crest-mesenchymal axis in creating the thymic microenvironment

EBNA2 binds to genomic intervals associated with multiple sclerosis and overlaps with vitamin D receptor occupancy.

Epigenetic mechanisms in multiple sclerosis and the major histocompatibility complex (MHC).

Epigenetics: molecular mechanisms and implications for disease.

Estrogen-vitamin D interaction in multiple sclerosis

FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency

Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells

GPC5 and lung cancer in multiple sclerosis

Genetic and environmental factors and the distribution of multiple sclerosis in Europe

Geography of hospital admissions for multiple sclerosis in England and comparison with the geography of hospital admissions for infectious mononucleosis: a descriptive study ⬇️

HLA-DRB1 confers increased risk of pediatric-onset MS in children with acquired demyelination ⬇️

Heterogeneity in multiple sclerosis: scratching the surface of a complex disease.

High reprint orders in medical journals and pharmaceutical industry funding: case-control study

Indispensable epigenetic control of thymic epithelial cell development and function by polycomb repressive complex 2

Inequities in advice on vitamin D?

Most brain disease-associated and eQTL haplotypes are not located within transcription factor DNase-seq footprints in brain

Multiple sclerosis and lung cancer: an unexpected inverse association.

Multiple sclerosis and risk of cancer: a meta-analysis

Next-generation sequencing in understanding complex neurological disease

No evidence for an effect of DNA methylation on multiple sclerosis severity at HLA-DRB1*15 or HLA-DRB5

Of mice and men: experimental autoimmune encephalitis and multiple sclerosis.

Rare variants in the CYP27B1 gene are associated with multiple sclerosis.

Relationship of UV exposure to prevalence of multiple sclerosis in England ⬇️

Revisiting the T-cell receptor alpha/delta locus and possible associations with multiple sclerosis.

Season of birth and anorexia nervosa ⬇️

Seasonality of admissions with multiple sclerosis in Scotland.

Smoking and multiple sclerosis: a matter of global importance

Targeted RNA sequencing enhances gene expression profiling of ultra-low input samples

The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function

The contribution of thymic tolerance to central nervous system autoimmunity

The crystal structure of human forkhead box N1 in complex with DNA reveals the structural basis for forkhead box family specificity

The epidemiology of multiple sclerosis in Scotland: inferences from hospital admissions.

The potential role of major histocompatibility complex class I in schizophrenia

The questionable effectiveness of sunscreen

Tuberculosis and diabetes mellitus: is vitamin D the missing link?

Variants in ST8SIA1 do not play a major role in susceptibility to multiple sclerosis in Canadian families

Visceral obesity and brain volume

Vitamin D and multiple sclerosis hospital admissions in Scotland.

Vitamin D and multiple sclerosis: an interaction between genes and environment

Vitamin D receptor ChIP-seq in primary CD4+ cells: relationship to serum 25-hydroxyvitamin D levels and autoimmune disease