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List of works by Raoul Charles Coombes

'Big ACTH' and calcitonin in an ectopic hormone secreting tumour of the liver

scientific article published on July 1, 1977

4-Hydroxyandrostenedione treatment for postmenopausal patients with breast cancer

scientific article published on 01 September 1992

4-hydroxyandrostenedione: a new treatment for postmenopausal patients with breast cancer

scientific article published on 01 January 1992

A Paracrine Role for Myoepithelial Cell-Derived FGF2 in the Normal Human Breast

scientific article published on July 10, 1997

A phase I study of the vitamin D analogue EB 1089 in patients with advanced breast and colorectal cancer

scientific article published on July 1, 1998

Absence of HPV 16 and 18 DNA in breast cancer

scientific article published on June 1, 1992

Adjuvant aminoglutethimide for postmenopausal patients with primary breast cancer: analysis at 8 years

scientific article published on 01 October 1992

Advancing breast cancer therapy by translational research: highlights of the Improving Care and Knowledge through Translational Research (IMPAKT) breast cancer conference

scientific article published on September 1, 2011

Agents affecting osteolysis in patients with breast cancer

scientific article published on January 1, 1979

An immunohistochemical survey of pS2 expression in human epithelial cancers

scientific article published on January 21, 1992

Assessment of Ki67 in Breast Cancer: Recommendations from the International Ki67 in Breast Cancer Working Group

scientific article published on September 29, 2011

Automated screening for micrometastases in bone marrow smears

scientific article published on August 9, 1988

Biochemical markers in bronchogenic carcinoma

scientific article published on October 1, 1978

Bone marrow micrometastases in primary breast cancer: Prognostic significance after 6 years' follow-up

scientific article published on 01 January 1991

CA-125 is not a useful marker in metastatic breast cancer

scientific article published on November 1, 1992

Calcium metabolism in breast cancer

scientific article published on March 1, 1977

Calcium metabolism in cancer.Studies using calcium isotopes and immunoassays for parathyroid hormone and calcitonin

scientific article published on November 1, 1976

Clinical and biological significance of HSP89 alpha in human breast cancer

scientific article published on February 1, 1992

Design and Rationale of a Randomised Comparison of Cyclophosphamide, Methotrexate and Fluorouracil vs Fluorouracil, Epirubicin and Cyclophosphamide in Node-Positive Premenopausal Women with Operable Breast Cancer

scientific article published on January 1, 1993

Down-regulation of a novel form of fibroblast growth factor receptor 1 in human breast cancer

scientific article published on January 1, 1997

Drug testing in the patient: toward personalized cancer treatment

scientific article published on 01 April 2015

EB1089: a new vitamin D analogue that inhibits the growth of breast cancer cells in vivo and in vitro

scientific article (publication date: 15 December 1992)

Ectopic hormone production by bronchial carcinomas in culture

scientific article published on January 1, 1976

Effect of basic fibroblast growth factor-saporin mitotoxin on breast cancer cell lines in vitro

scientific article published on 01 March 1997

Effect of tamoxifen or anastrozole on steroid sulfatase activity and serum androgen concentrations in postmenopausal women with breast cancer

scientific article published on 01 April 2011

Effects of synthetic vitamin D analogues on breast cancer cell proliferation in vivo and in vitro

scientific article published on August 18, 1992

Erratum to: Lapatinib access into normal brain and brain metastases in patients with Her-2 overexpressing breast cancer

scientific article published on 8 September 2017

Evaluation of applying IHC4 as a prognostic model in the translational study of Intergroup Exemestane Study (IES): PathIES.

scientific article published on 24 November 2017

Failure of indomethacin to reduce hypercalcemia in patients with breast cancer

scientific article published on 01 December 1976

Failure to detect intra-abdominal metastases from breast cancer: a case for staging laparotomy

scientific article published on July 15, 1978

Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer.

scientific article published on 17 October 2016

Human Estrogen Receptor β Binds DNA in a Manner Similar to and Dimerizes with Estrogen Receptor α

scientific article (publication date: 10 October 1997)

IPET study: an FLT-PET window study to assess the activity of the steroid sulfatase inhibitor irosustat in early breast cancer.

scientific article published on 09 August 2017

Idoxifene is equipotent to tamoxifen in inhibiting mammary carcinogenesis but forms lower levels of hepatic DNA adducts

scientific article published on January 1, 1997

Immunocytochemical determination of estrogen receptor, progesterone receptor, and 1,25-dihydroxyvitamin D3 receptor in breast cancer and relationship to prognosis

scientific article published on January 1, 1991

Immunoreactive calcitonin production by human lung carcinoma cells in culture

scientific article published on September 1, 1975

Inhibitor Selectivity for Cyclin-Dependent Kinase 7: A Structural, Thermodynamic, and Modelling Study.

scientific article published on 26 January 2017

Irosustat: a first-generation steroid sulfatase inhibitor in breast cancer

scientific article published on February 1, 2011

Is the presence of small volume disease in the sentinel node an indication for axillary clearance?

scientific article published on June 19, 2012

Latest advances in the medical treatment of cancer: a 2011 snapshot

scientific article published on January 1, 2012

Latest therapeutic advances from the ASCO 2010 Annual Meeting

scientific article published on November 1, 2010

Management and Outcome of HER2-Positive Early Breast Cancer Treated With or Without Trastuzumab in the Adjuvant Trastuzumab Era

scientific article published on April 11, 2011

Measurement of 1,25-dihydroxyvitamin D3 receptors in breast cancer and their relationship to biochemical and clinical indices

scientific article published on 01 April 1984

MiR-106b~25 cluster regulates multidrug resistance in an ABC transporter-independent manner via downregulation of EP300.

scientific article published on 12 November 2015

Monitoring Early Response to Taxane Therapy in Advanced Breast Cancer with Circulating Tumor Cells and [ 18 F] 3´-deoxy-3´-Fluorothymidine PET: A Pilot Study

scientific article published on April 1, 2012

Mutation Analysis of Cell-Free DNA and Single Circulating Tumor Cells in Metastatic Breast Cancer Patients with High Circulating Tumor Cell Counts.

scientific article published on 22 June 2016

Next Generation Sequencing of Circulating Cell-Free DNA for Evaluating Mutations and Gene Amplification in Metastatic Breast Cancer

scientific article

Normal plasma calcitonin: circadian variation and response to stimuli

scientific article published on 01 April 1977

Nucleoside excretion in breast cancer: comparison with other biochemical tumour-index-substances

scientific article published on 01 January 1979

Oestrone sulphatase activity in mammary tumours and the liver of N-nitrosomethylurea treated rats

scientific article published on January 1, 1992

Paclitaxel-induced nuclear translocation of FOXO3a in breast cancer cells is mediated by c-Jun NH2-terminal kinase and Akt.

scientific article published on January 2006

Pharmacokinetics and pharmacodynamics of the aromatase inhibitor 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione in patients with postmenopausal breast cancer

scientific article published on January 1, 1991

Phase I and endocrine study of exemestane (FCE 24304), a new aromatase inhibitor, in postmenopausal women

scientific article published on November 1, 1992

Physical Test for Distant Metastases in Patients with Breast Cancer

scientific article published on 01 September 1980

Polymerase chain reaction-aided analysis of gene expression in frozen tissue sections

scientific article published on 01 February 1992

Proceedings: Immunoreactive calcitonin in patients with carcinomata

scientific article published on 01 July 1975

Randomised trial of chemotherapy versus endocrine therapy in patients presenting with locally advanced breast cancer (a pilot study)

scientific article published on February 1, 1991

Reporter gene assay demonstrates functional differences in estrogen receptor activity in purified breast cancer cells: A pilot study

scientific article published on December 10, 2003

Resolution of late-onset asthma following high-dose chemotherapy

scientific article published on October 1, 2003

Results of the phase IIa RADICAL trial of the FGFR inhibitor AZD4547 in endocrine resistant breast cancer

scientific article published on 10 June 2022

Secretion of immunoreactive calcitonin by human breast carcinomas

scientific article published on October 25, 1975

Shallow WGS of individual CTCs identifies actionable targets for informing treatment decisions in metastatic breast cancer

scientific article published in 2022

Significance of heat-shock protein-90 as a prognostic indicator in breast-cancer

scientific article published on June 1, 1993

Stratified, precision or personalised medicine? Cancer services in the 'real world' of a London hospital.

scientific article

The Relationship Between Micrometastases in the Bone Marrow, Histopathologic Features of the Primary Tumor in Breast Cancer and Prognosis

scientific article published on 01 July 1988

The detection of micrometastases in the peripheral blood and bone marrow of patients with breast cancer using immunohistochemistry and reverse transcriptase polymerase chain reaction for keratin 19

scientific article published on 01 May 1997

Time to TEAM: exemestane, or tamoxifen then exemestane?

scientific article published on January 22, 2011

Tumour suppressor EP300, a modulator of paclitaxel resistance and stemness, is downregulated in metaplastic breast cancer.

scientific article

Viable circulating tumour cell detection using multiplex RNA in situ hybridisation predicts progression-free survival in metastatic breast cancer patients

scientific article published on April 26, 2012

p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells

scientific article published on 16 August 2017