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List of works by Henry Krum

"Bisoprolol dose-response relationship in patients with congestive heart failure: a subgroup analysis in the cardiac insufficiency bisoprolol study(CIBIS II)," by Simon T.

scientific article published in February 2004

3',4'-Bis-difluoromethoxycinnamoylanthranilate (FT061): an orally-active antifibrotic agent that reduces albuminuria in a rat model of progressive diabetic nephropathy.

scientific article published on 8 October 2013

3′,4′-Dihydroxyflavonol Antioxidant Attenuates Diastolic Dysfunction and Cardiac Remodeling in Streptozotocin-Induced Diabetic m(Ren2)27 Rats ⬇️

scientific article published on July 28, 2011

A Phase II Dose-Escalation Study of Allogeneic Mesenchymal Precursor Cells in Patients With Ischemic or Nonischemic Heart Failure

scientific article published on 6 July 2015

A bioavailability study of cyclosporine: comparison of Neoral versus Cysporin in stable heart transplant recipients

scientific article published on September 2009

A feeling in the waters: diagnosis of heart failure using urinary natriuretic peptides

scientific article published in February 2004

A novel algorithm for individualized cardiac resynchronization therapy: Rationale and design of the adaptive cardiac resynchronization therapy trial ⬇️

scientific article published on May 1, 2012

A novel hydrogen sulfide prodrug, SG1002, promotes hydrogen sulfide and nitric oxide bioavailability in heart failure patients

scientific article published on August 2015

A purpose-synthesised anti-fibrotic agent attenuates experimental kidney diseases in the rat

scientific article

A randomized controlled study of finerenone vs. eplerenone in patients with worsening chronic heart failure and diabetes mellitus and/or chronic kidney disease

scientific article published on 29 April 2016

A selective endothelin-receptor antagonist to reduce blood pressure in patients with treatment-resistant hypertension: a randomised, double-blind, placebo-controlled trial

scientific article published on 11 September 2009

A statement on ethics from the HEART Group

scientific article

Acute effects of caffeine on heart rate variability

scientific article published in October 2002

Acute heart failure in the elderly: differences in clinical characteristics, outcomes, and prognostic factors in the VERITAS Study

scientific article published on 5 January 2015

Adherence, adaptation and acceptance of elderly chronic heart failure patients to receiving healthcare via telephone-monitoring

article

Aldosterone blockade in post-acute myocardial infarction heart failure.

scientific article published on October 2006

Aldosterone receptor antagonists for hypertension: what do they offer?

scientific article

Aliskiren, ALTITUDE, and the implications for ATMOSPHERE.

scientific article published on April 2012

Aliskiren, Enalapril, or Aliskiren and Enalapril in Heart Failure

scientific article published on 4 April 2016

Altered sympathetic and parasympathetic activity in lung transplantation patients at rest and following autonomic perturbation

scientific article published in October 2002

Amino-terminal-pro-B-type natriuretic peptide levels and low diastolic blood pressure: potential relevance to the diastolic J-curve

scientific article published in November 2014

Analysis of randomized controlled trials on the effect of magnitude of heart rate reduction on clinical outcomes in patients with systolic chronic heart failure receiving beta-blockers

scientific article published on 21 February 2008

Angiotensin receptor neprilysin inhibitor LCZ696 attenuates cardiac remodeling and dysfunction after myocardial infarction by reducing cardiac fibrosis and hypertrophy

scientific article published on 31 October 2014

Apoptosis signal-regulating kinase 1 inhibition attenuates cardiac hypertrophy and cardiorenal fibrosis induced by uremic toxins: Implications for cardiorenal syndrome

scientific article published on 6 November 2017

Are all outcomes in chronic heart failure rated equally? An argument for a patient-centred approach to outcome assessment

scientific article published on March 2014

Are beta-blockers needed in patients receiving spironolactone for severe chronic heart failure? An analysis of the COPERNICUS study

scientific article published in January 2006

Are β-blockers as efficacious in patients with diabetes mellitus as in patients without diabetes mellitus who have chronic heart failure? A meta-analysis of large-scale clinical trials ⬇️

scientific article published on November 1, 2003

Aspirin and Tranexamic Acid for Coronary Artery Surgery (ATACAS) Trial: rationale and design

scientific article published on 26 November 2007

Aspirin does not reduce the clinical benefits of the mineralocorticoid receptor antagonist eplerenone in patients with systolic heart failure and mild symptoms: an analysis of the EMPHASIS-HF study

scientific article

Association of persistent or worsened echocardiographic dyssynchrony with unfavourable clinical outcomes in heart failure patients with narrow QRS width: a subgroup analysis of the EchoCRT trial

scientific article published on 30 August 2015

Attitudes of Patients and Prescribing Clinicians to Polypharmacy and Medication Withdrawal in Heart Failure.

scientific article

B-type natriuretic peptide testing, clinical outcomes, and health services use in emergency department patients with dyspnea: a randomized trial

scientific article published in March 2009

B-type natriuretic peptide-guided heart failure therapy: A meta-analysis

scientific article published in March 2010

Baseline characteristics of the Nateglinide and Valsartan Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) trial population: comparison with other diabetes prevention trials

scientific article published on 23 February 2010

Baseline factors associated with congestive heart failure in patients receiving etoricoxib or diclofenac: multivariate analysis of the MEDAL program

scientific article published on 19 April 2009

Beta-blockers in chronic heart failure: what have we learned? What do we still need to know?

scientific article

Blood Pressure and Cardiovascular Outcomes in Patients Taking Nonsteroidal Antiinflammatory Drugs ⬇️

scientific article published on May 25, 2011

Blood pressure effects of COX-2 inhibitors.

scientific article published on January 2006

Bush telegraph. Improving outcomes for rural and remote patients with chronic heart failure

scientific article published on 01 January 2004

CHAT--a study of a nurse-led system of care

scientific article published on 01 October 2006

CONFIRMATION OF KEY TREAT FINDINGS IN RED-HF, A PLACEBO CONTROLLED HEART FAILURE TRIAL

scientific article published in April 2014

Can Renin Status Predict the Antihypertensive Efficacy of Eplerenone Add‐On Therapy? ⬇️

scientific article published on November 1, 2003

Can medications be safely withdrawn in patients with stable chronic heart failure? systematic review and meta-analysis

scientific article published on 18 April 2014

Can the blood pressure effects of COX-2 selective inhibitors be explained by changes in plasma aldosterone levels?

scientific article published in October 2006

Cardiac Resynchronization Therapy in Patients With Heart Failure and Narrow QRS Complexes

scientific article published in March 2018

Cardiac-resynchronization therapy in heart failure with a narrow QRS complex

scientific article

Cardiorenal fibrosis and dysfunction in aging: Imbalance in mediators and regulators of collagen

scientific article published on 13 January 2016

Cardiorenal syndrome: acute kidney injury secondary to cardiovascular disease and role of protein-bound uraemic toxins

scientific article

Cardiorenal syndrome: pathophysiology, preclinical models, management and potential role of uraemic toxins.

scientific article published on August 2012

Cardiorenal syndrome: role of protein-bound uremic toxins

scientific article published on 31 December 2014

Cardiovascular Magnetic Resonance GUIDEd management of mild-moderate left ventricular systolic Heart Failure (CMR GUIDE HF): study protocol for a randomised controlled trial.

scientific article

Cardiovascular effects of selective cyclooxygenase-2 inhibitors

scientific article published on March 2004

Cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison

scientific article

Cardiovascular role of urotensin II: effect of chronic infusion in the rat.

scientific article published in October 2004

Catalytic degradation of vitamin D up-regulated protein 1 mRNA enhances cardiomyocyte survival and prevents left ventricular remodeling after myocardial ischemia

scientific journal article

Catheter-based renal denervation for treatment of patients with treatment-resistant hypertension: 36 month results from the SYMPLICITY HTN-2 randomized clinical trial.

scientific article

Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study

scientific article

Celecoxib, but not rofecoxib or naproxen, attenuates cardiac hypertrophy and fibrosis induced in vitro by angiotensin and aldosterone

scientific article published on 24 May 2010

Chronic Kidney Disease-Induced Cardiac Fibrosis Is Ameliorated by Reducing Circulating Levels of a Non-Dialysable Uremic Toxin, Indoxyl Sulfate ⬇️

scientific article published on July 19, 2012

Chronic heart failure--optimising care in general practice.

scientific article

Chronic heart failure.

scientific article

Chronic urotensin II receptor antagonist treatment does not alter hypertrophy or fibrosis in a rat model of pressure-overload hypertrophy.

scientific article

Circuit Resistance Training in Chronic Heart Failure Improves Skeletal Muscle Mitochondrial ATP Production Rate—A Randomized Controlled Trial

article

Clinical benefit of eplerenone in patients with mild symptoms of systolic heart failure already receiving optimal best practice background drug therapy: analysis of the EMPHASIS-HF study

scientific article

Clinical benefits of eplerenone in patients with systolic heart failure and mild symptoms when initiated shortly after hospital discharge: analysis from the EMPHASIS-HF trial

scientific article published on 20 June 2015

Clinical effects of endothelin receptor antagonism with bosentan in patients with severe chronic heart failure: results of a pilot study

scientific article published in February 2005

Clinical effects of initial 6 months monotherapy with bisoprolol versus enalapril in the treatment of patients with mild to moderate chronic heart failure. Data from the CIBIS III Trial

scientific article

Clinical investigations of statins in heart failure: ventricular function and anti-remodeling

scientific article published on 01 April 2008

Clinical outcomes according to QRS duration and morphology in the Eplerenone in Mild Patients: Hospitalization and SurvIval Study in Heart Failure (EMPHASIS-HF).

scientific article

Clinical outcomes with synchronized left ventricular pacing: Analysis of the adaptive CRT trial ⬇️

scientific article published on July 11, 2013

Clinical service organisation for heart failure

scientific article (published 2012-09-12)

Clozapine-associated myocarditis: a review of 116 cases of suspected myocarditis associated with the use of clozapine in Australia during 1993-2003

scientific article

Coenzyme Q10 in cardiovascular disease

scientific article published on 16 March 2007

Combined angiotensin receptor blockade and neprilysin inhibition attenuates angiotensin-II mediated renal cellular collagen synthesis

Comment on "Clinical trials update from the European Society of Cardiology meeting 2005: CIBIS-III, by JGF Cleland and others".

scientific article published in March 2006

Comparison of omapatrilat and enalapril in patients with chronic heart failure: the Omapatrilat Versus Enalapril Randomized Trial of Utility in Reducing Events (OVERTURE).

scientific article published in August 2002

Comparison of predictive performance of renal function estimation equations for all-cause and cardiovascular mortality in an elderly hypertensive population

scientific article published on 18 September 2014

Comparison of treatment initiation with bisoprolol vs. enalapril in chronic heart failure patients: rationale and design of CIBIS-III.

scientific article published in June 2004

Contemporary predictors of coronary artery disease in patients referred for angiography

scientific article published in June 2010

Contributors

Cost effectiveness of eplerenone in patients with chronic heart failure

scientific article published on June 2014

Cost-effectiveness of eplerenone in patients with systolic heart failure and mild symptoms

scientific article

Could risk stratification aid the treatment of patients with acute decompensated heart failure?

scientific article published in July 2005

Current evidence on treatment of patients with chronic systolic heart failure and renal insufficiency: practical considerations from published data

scientific article

Current modalities for invasive and non-invasive monitoring of volume status in heart failure: Table 1 ⬇️

scientific article published on 09 May 2012

Current role of neprilysin inhibitors in hypertension and heart failure

scientific article published on 14 May 2014

Current status of endothelin blockade for the treatment of cardiovascular and pulmonary vascular disease.

scientific article

Cytochrome P450 drug interactions within the HMG-CoA reductase inhibitor class: are they clinically relevant?

scientific article

Daily home BNP monitoring in heart failure for prediction of impending clinical deterioration: results from the HOME HF study

scientific article published on 4 January 2018

Decade in review--heart failure: 10 Years of progress in HF research--what have we learned?

scientific article published on 02 September 2014

Demographics and concomitant disorders in heart failure

scientific article

Device-based antihypertensive therapy: therapeutic modulation of the autonomic nervous system

scientific article published on January 2011

Diabetes, left ventricular systolic dysfunction, and chronic heart failure

scientific article published on 18 April 2008

Differences between beta-blockers in patients with chronic heart failure and chronic obstructive pulmonary disease: a randomized crossover trial

scientific article published in April 2010

Differential blood pressure effects of ibuprofen, naproxen, and celecoxib in patients with arthritis: the PRECISION-ABPM (Prospective Randomized Evaluation of Celecoxib Integrated Safety Versus Ibuprofen or Naproxen Ambulatory Blood Pressure Measure

scientific article

Differential effect of urotensin II on vascular tone in normal subjects and patients with chronic heart failure

scientific article published on 8 March 2004

Digoxin Withdrawal Worsens Clinical Status in Stable Patients With Heart Failure Receiving Optimal Contemporaneous Therapy—A Randomized Controlled Trial

scientific article published on 10 July 2015

Dipeptidyl peptidase-4 inhibitors and cardiovascular outcomes: meta-analysis of randomized clinical trials with 55,141 participants

scientific article (publication date: August 2014)

Direct Left Atrial Pressure Monitoring in Severe Heart Failure: Long-Term Sensor Performance ⬇️

scientific article published on October 14, 2010

Direct actions of urotensin II on the heart: implications for cardiac fibrosis and hypertrophy

scientific article published on 3 July 2003

Direct left atrial pressure monitoring in ambulatory heart failure patients: initial experience with a new permanent implantable device

scientific article published on 3 December 2007

Direct renin inhibition in addition to or as an alternative to angiotensin converting enzyme inhibition in patients with chronic systolic heart failure: rationale and design of the Aliskiren Trial to Minimize OutcomeS in Patients with HEart failuRE (

article

Diuretics in the treatment of heart failure: mainstay of therapy or potential hazard?

scientific article published in June 2006

Divergent results using clinic and ambulatory blood pressures: report of a darusentan-resistant hypertension trial

scientific article published on 4 October 2010

Do COX-2 inhibitors raise blood pressure more than nonselective NSAIDs and placebo? An updated meta-analysis

scientific article published in December 2009

Do Cardiac Rehabilitation Programs Offer Cardiopulmonary Resuscitation Training in Australia and New Zealand?

scientific article published on 18 December 2015

Do elderly systolic heart failure patients benefit from beta blockers to the same extent as the non-elderly? Meta-analysis of >12,000 patients in large-scale clinical trials

scientific article published on 01 April 2005

Does indoxyl sulfate, a uraemic toxin, have direct effects on cardiac fibroblasts and myocytes?

scientific article published on 4 January 2010

Does the presence of heart failure alter prescribing of drug therapy after myocardial infarction? A multicentre study

scientific article published on 01 August 2006

Double-blind, randomized, placebo-controlled study of high-dose HMG CoA reductase inhibitor therapy on ventricular remodeling, pro-inflammatory cytokines and neurohormonal parameters in patients with chronic systolic heart failure

scientific article published in February 2007

Drug discovery for heart failure: a new era or the end of the pipeline?

scientific article published on February 2007

Drug therapy of chronic heart failure in the elderly: the current state of clinical-trial evidence

scientific article

Early and delayed tranilast treatment reduces pathological fibrosis following myocardial infarction.

scientific article

Effect of Gender on Outcomes After Cardiac Resynchronization Therapy in Patients With a Narrow QRS Complex: A Subgroup Analysis of the EchoCRT Trial

scientific article published on June 2016

Effect of Renal Sympathetic Denervation on Glucose Metabolism in Patients With Resistant Hypertension ⬇️

scientific article published on April 25, 2011

Effect of Ularitide on Cardiovascular Mortality in Acute Heart Failure

scientific article published on 12 April 2017

Effect of age and sex on efficacy and tolerability of β blockers in patients with heart failure with reduced ejection fraction: individual patient data meta-analysis

scientific article

Effect of angiotensin II receptor blockade on autonomic nervous system function in patients with essential hypertension

scientific article

Effect of atorvastatin on cardiac remodelling and mortality in rats following hyperglycemia and myocardial infarction.

scientific article published on 22 April 2009

Effect of beta-adrenergic blockade with carvedilol on cachexia in severe chronic heart failure: results from the COPERNICUS trial

scientific article published on 27 February 2017

Effect of cardiac resynchronization therapy in patients with diabetes randomized in EchoCRT.

scientific article published on 11 November 2016

Effect of carvedilol on the morbidity of patients with severe chronic heart failure: results of the carvedilol prospective randomized cumulative survival (COPERNICUS) study

scientific article

Effect of endothelin blockade on basal and stimulated forearm blood flow in patients with essential hypertension

scientific article published on 01 March 2002

Effect of exogenous urotensin-II on vascular tone in skin microcirculation of patients with essential hypertension

scientific article published in September 2005

Effect of insulin glargine and n-3FA on carotid intima-media thickness in people with dysglycemia at high risk for cardiovascular events: the glucose reduction and atherosclerosis continuing evaluation study (ORIGIN-GRACE).

scientific article published on 05 April 2013

Effect of intensive structured care on individual blood pressure targets in primary care: multicentre randomised controlled trial

scientific article

Effect of nateglinide on the incidence of diabetes and cardiovascular events

scientific article published on 14 March 2010

Effect of the urotensin receptor antagonist palosuran in hypertensive patients with type 2 diabetic nephropathy

scientific article published on 15 March 2010

Effect of valsartan added to background ACE inhibitor therapy in patients with heart failure: results from Val-HeFT.

scientific article

Effect of valsartan on the incidence of diabetes and cardiovascular events

scientific article

Effect on mode of death of heart failure treatment started with bisoprolol followed by Enalapril, compared to the opposite order: results of the randomized CIBIS III trial

scientific article published in April 2011

Effect on survival and hospitalization of initiating treatment for chronic heart failure with bisoprolol followed by enalapril, as compared with the opposite sequence: results of the randomized Cardiac Insufficiency Bisoprolol Study (CIBIS) III.

scientific article published on 4 September 2005

Effects of Renal Denervation on Sympathetic Activation, Blood Pressure, and Glucose Metabolism in Patients with Resistant Hypertension ⬇️

scientific article published on February 2, 2012

Effects of Vildagliptin on Ventricular Function in Patients With Type 2 Diabetes Mellitus and Heart Failure: A Randomized Placebo-Controlled Trial

scientific article published on 11 October 2017

Effects of a Rho kinase inhibitor on pressure overload induced cardiac hypertrophy and associated diastolic dysfunction.

scientific article

Effects of a novel aldosterone synthase inhibitor for treatment of primary hypertension: results of a randomized, double-blind, placebo- and active-controlled phase 2 trial

scientific article published on 10 October 2011

Effects of beta-adrenergic antagonists in patients with chronic kidney disease: a systematic review and meta-analysis

scientific article published on September 2011

Effects of initiating carvedilol in patients with severe chronic heart failure: results from the COPERNICUS Study

scientific article published in February 2003

Effects of tezosentan on symptoms and clinical outcomes in patients with acute heart failure: the VERITAS randomized controlled trials

scientific article

Efficacy of eplerenone added to renin-angiotensin blockade in hypertensive patients

scientific article published in August 2002

Efficacy of β blockers in patients with heart failure plus atrial fibrillation: an individual-patient data meta-analysis

scientific article

Eplerenone and atrial fibrillation in mild systolic heart failure: results from the EMPHASIS-HF (Eplerenone in Mild Patients Hospitalization And SurvIval Study in Heart Failure) study

scientific article published in May 2012

Eplerenone and new-onset diabetes in patients with mild heart failure: results from the Eplerenone in Mild Patients Hospitalization and Survival Study in Heart Failure (EMPHASIS-HF).

scientific article published on 19 May 2012

Eplerenone for the treatment of cardiovascular disorders

scientific article published on July 2012

Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms ⬇️

scientific article published on November 14, 2010

Eplerenone in patients with systolic heart failure and mild symptoms: analysis of repeat hospitalizations

scientific article published on 05 October 2012

Eplerenone in the treatment of chronic heart failure.

scientific article published on May 2004

Eplerenone reduces mortality 30 days after randomization following acute myocardial infarction in patients with left ventricular systolic dysfunction and heart failure

scientific article published in August 2005

Eplerenone. Pharmacia

scientific article published on March 1, 2003

Evaluation and optimization of antifibrotic activity of cinnamoyl anthranilates

scientific article published on 7 October 2009

Evaluation of the effects of urotensin II and soluble epoxide hydrolase inhibitor on skin microvessel tone in healthy controls and heart failure patients

scientific article

Expanding indications for pacing in chronic heart failure.

scientific article published in May 2009

FT011, a new anti-fibrotic drug, attenuates fibrosis and chronic heart failure in experimental diabetic cardiomyopathy

scientific article published on 14 March 2012

FT23, an orally active antifibrotic compound, attenuates structural and functional abnormalities in an experimental model of diabetic cardiomyopathy

scientific article published in August 2012

Factors associated with blood pressure changes in patients receiving diclofenac or etoricoxib: results from the MEDAL study.

scientific article

Factors influencing family physician adherence to hypertension treatment guideline recommendations on the initiation of pharmacotherapy: questionnaire survey

scientific article published on 01 January 2003

Feasibility of conducting a primary prevention trial of low-dose aspirin for major adverse cardiovascular events in older people in Australia: results from the ASPirin in Reducing Events in the Elderly (ASPREE) pilot study.

scientific article published in July 2008

Fibrosis as a therapeutic target post-myocardial infarction.

scientific article

Geographic Differences in Patients in a Global Acute Heart Failure Clinical Trial (from the ASCEND-HF Trial).

scientific article

Guidelines for the prevention, detection and management of people with chronic heart failure in Australia 2006.

scientific article published on November 2006

Health-Related Quality of Life After Renal Denervation in Patients With Treatment-Resistant Hypertension ⬇️

scientific article published on October 15, 2012

Heart Failure Clinical Trials in East and Southeast Asia: Understanding the Importance and Defining the Next Steps

scientific article published on June 2016

Heart failure and nephropathy: catastrophic and interrelated complications of diabetes

scientific article published on 7 December 2005

Heart failure care in low- and middle-income countries: a systematic review and meta-analysis

scientific article

Heart failure in diabetes: effects of anti-hyperglycaemic drug therapy

scientific article published on May 2015

Heart failure, ventricular dysfunction and risk factor prevalence in Australian Aboriginal peoples: the Heart of the Heart Study

scientific article published on 11 August 2012

Heart failure: preventing disease and death worldwide

scientific article published on September 2014

History of hypertension and eplerenone in patients with acute myocardial infarction complicated by heart failure

scientific article published on 16 June 2008

How does renal denervation lower blood pressure and when should this technique be considered for the treatment of hypertension?

scientific article

Images in cardiovascular medicine. Dynamic myocardial ischemia caused by circumflex artery stenosis detected by a new implantable left atrial pressure monitoring device

scientific article published in April 2006

Impact of Statin Therapy on Clinical Outcomes in Chronic Heart Failure Patients According to Beta-Blocker Use: Results of CIBIS II

scientific article published on 08 September 2006

Impact of a Novel Adaptive Optimization Algorithm on 30-Day Readmissions: Evidence From the Adaptive CRT Trial

scientific article

Impact of eplerenone on cardiovascular outcomes in heart failure patients with hypokalaemia

Impact of heart failure and changes to volume status on liver stiffness: non-invasive assessment using transient elastography

scientific article published on 20 April 2012

Impact of home versus clinic-based management of chronic heart failure: the WHICH? (Which Heart Failure Intervention Is Most Cost-Effective & Consumer Friendly in Reducing Hospital Care) multicenter, randomized trial

scientific article published in October 2012

Impaired pulmonary diffusing capacity and hypoxia in heart failure correlates with central sleep apnea severity

scientific article published on 15 January 2008

In vitro inhibitory effects of atorvastatin on cardiac fibroblasts: implications for ventricular remodelling

scientific article published in September 2005

Incidence of heart failure in 6083 elderly hypertensive patients: the Second Australian National Blood Pressure Study (ANBP2).

scientific article published on 28 October 2015

Incidence, determinants, and prognostic significance of hyperkalemia and worsening renal function in patients with heart failure receiving the mineralocorticoid receptor antagonist eplerenone or placebo in addition to optimal medical therapy: result

scientific article published on 02 December 2013

Increased circulating urotensin II in cirrhosis: potential implications in liver disease.

scientific article published on 25 August 2007

Increased risk of stroke with darbepoetin alfa in anaemic heart failure patients with diabetes and chronic kidney disease

scientific article

Individual patient data meta-analysis of beta-blockers in heart failure: rationale and design ⬇️

scientific article published on January 18, 2013

Influence of pretreatment systolic blood pressure on the effect of carvedilol in patients with severe chronic heart failure: the Carvedilol Prospective Randomized Cumulative Survival (COPERNICUS) study

scientific article published in April 2004

Inhibition of protein kinase C reduces left ventricular fibrosis and dysfunction following myocardial infarction

scientific article published on 01 August 2005

International expert consensus statement: Percutaneous transluminal renal denervation for the treatment of resistant hypertension

scientific article published on 18 September 2013

International variation in use of oral anticoagulation among heart failure patients with atrial fibrillation

scientific article published on 27 March 2012

Intra-coronary high-dose CD34+ stem cells in patients with chronic ischemic heart disease: a 12-month follow-up.

scientific article published on 20 June 2005

Investigation of a novel algorithm for synchronized left-ventricular pacing and ambulatory optimization of cardiac resynchronization therapy: results of the adaptive CRT trial

scientific article published on 14 July 2012

Is target dose of beta-blocker more important than achieved heart rate or heart rate change in patients with systolic chronic heart failure?

scientific article published in April 2010

Letter by Connelly et al regarding article, "Diastolic stiffness of the failing diabetic heart: importance of fibrosis, advanced glycation end products, and myocyte resting tension"

scientific article published on 01 June 2008

Long-Term Effect of Endothelin Receptor Antagonism With Bosentan on the Morbidity and Mortality of Patients With Severe Chronic Heart Failure: Primary Results of the ENABLE Trials

scientific article published in May 2017

Long-term survival following the development of heart failure in an elderly hypertensive population

scientific article published on 31 August 2017

Losartan increases bradykinin levels in hypertensive humans

scientific article published on 17 January 2005

Losing ALTITUDE? How should ASTRONAUT launch into ATMOSPHERE.

scientific article published on 29 August 2013

Measurement of troponin and natriuretic peptides shortly after admission in patients with heart failure-does it add useful prognostic information? An analysis of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Stud

scientific article

Medical therapy for chronic heart failure ⬇️

scientific article published on August 20, 2011

Medical therapy versus implantable cardioverter -defibrillator in preventing sudden cardiac death in patients with left ventricular systolic dysfunction and heart failure: a meta-analysis of > 35,000 patients

scientific article published on 22 February 2014

Meta-analysis of cyclooxygenase-2 inhibitors and their effects on blood pressure

scientific article published on 14 February 2005

Meta-analysis: effect of B-type natriuretic peptide testing on clinical outcomes in patients with acute dyspnea in the emergency setting

scientific article

Microglia activation in the hypothalamic PVN following myocardial infarction.

scientific article

Mineralcorticoid antagonists in heart failure

scientific article

Moderate-intensity resistance exercise training in patients with chronic heart failure improves strength, endurance, heart rate variability, and forearm blood flow.

scientific article published in February 2004

Morbidity, mortality, physiologic and functional parameters in elderly and non-elderly patients in the Valsartan Heart Failure Trial (Val-HeFT).

scientific article published in December 2004

More Changing Times at Cardiovascular Therapeutics

Mortality and target haemoglobin concentrations in anaemic patients with chronic kidney disease treated with erythropoietin: a meta-analysis

scientific article published on February 2007

N-terminal B-type natriuretic peptide and the association with left ventricular diastolic function in a population at high risk of incident heart failure: results of the SCReening Evaluationof the Evolution of New-Heart Failure Study (SCREEN-HF).

scientific article

NT-proB natriuretic peptide, risk factors and asymptomatic left ventricular dysfunction: results of the SCReening Evaluation of the Evolution of New Heart Failure study (SCREEN-HF).

scientific article published on 7 September 2013

NT-proBNP in severe chronic heart failure: rationale, design and preliminary results of the COPERNICUS NT-proBNP substudy

scientific article published in March 2004

Nebulized furosemide for the management of dyspnea: does the evidence support its use?

scientific article published on 12 May 2008

Neprilysin inhibitors preserve renal function in heart failure

scientific article published on 06 November 2014

New developments in the pharmacological treatment of chronic heart failure

scientific article

New medical therapies for heart failure

scientific article published on 29 September 2015

New therapeutic approaches to resistant hypertension

scientific article published on August 2010

New treatment for old disease: management of resistant hypertension by percutaneous renal sympathetic denervation

scientific article published on 23 July 2013

Noninvasive calibration of cardiac pressure transducers in patients with heart failure: an aid to implantable hemodynamic monitoring and therapeutic guidance

scientific article published in September 2006

Norfloxacin treatment for clinically significant portal hypertension: results of a randomised double-blind placebo-controlled crossover trial.

scientific article published on 29 July 2008

Novel Drug Treatments for Hypertension

Novel procedure- and device-based strategies in the management of systemic hypertension

scientific article published on 18 January 2011

Novel therapies blocking the renin-angiotensin-aldosterone system in the management of hypertension and related disorders

scientific article published on January 2007

Novel therapies in acute and chronic heart failure ⬇️

scientific article published on March 23, 2012

Nurse-Led Titration of β-Adrenoreceptor Blocking Agents in Chronic Heart Failure Patients in the Community

scientific article published on 24 December 2010

Nurse-led titration of angiotensin converting enzyme inhibitors, beta-adrenergic blocking agents and angiotensin receptor blockers for patients with left ventricular systolic dysfunction

scientific article

Nurse-led titration of angiotensin converting enzyme inhibitors, beta-adrenergic blocking agents, and angiotensin receptor blockers for people with heart failure with reduced ejection fraction

scientific article

Nursing sans frontières: a three year case study of multi-state registration to support nursing practice using information technology.

scientific article published in September 2006

Optimising management of chronic heart failure

scientific article published on 16 November 2009

Patient characteristics from a regional multicenter database of acute decompensated heart failure in Asia Pacific (ADHERE International-Asia Pacific).

scientific article published on 8 October 2011

Patient preferences and willingness-to-pay for a home or clinic based program of chronic heart failure management: findings from the Which? trial

scientific article

Peptidomic profiles of post myocardial infarction rats affinity depleted plasma using matrix-assisted laser desorption/ionization time of flight (MALDI-ToF) mass spectrometry

scientific article

Pharmacologic management of the cardiorenal syndrome in heart failure

scientific article published on June 2009

Pharmacological venous thromboembolism prophylaxis in hospitalized medical patients: a meta-analysis of randomized controlled trials

scientific article

Phase 1 single dose studies to optimize the pharmacokinetics of DG17, a novel HIV-protease inhibitor pro-drug, using sodium bicarbonate and ritonavir

scientific article published in May 2008

Physician-directed patient self-management of left atrial pressure in advanced chronic heart failure

scientific article published on 22 February 2010

Physiologic determinants of endothelin concentrations in human saliva.

scientific article published in December 2003

Polypharmacy in heart failure - Is reducing medication safe?

scientific article published on 9 October 2015

Practical recommendations for the use of ACE inhibitors, beta-blockers, aldosterone antagonists and angiotensin receptor blockers in heart failure: putting guidelines into practice

scientific article published in August 2005

Predictors and Associations With Outcomes of Length of Hospital Stay in Patients With Acute Heart Failure: Results From VERITAS.

scientific article published on 22 December 2015

Predictors of incident heart failure hospitalizations among patients with impaired glucose tolerance: insight from the Nateglinide And Valsartan in Impaired Glucose Tolerance Outcomes Research study

scientific article

Predictors of normotension on withdrawal of antihypertensive drugs in elderly patients: prospective study in second Australian national blood pressure study cohort

scientific article

Prevalence of heart failure in Australia: a systematic review

scientific article

Prevention of diabetes and reduction in major cardiovascular events in studies of subjects with prediabetes: meta-analysis of randomised controlled clinical trials

scientific article published on 30 August 2011

Prognostic Value of Insulin-Like Growth Factor-Binding Protein 7 in Patients with Heart Failure and Preserved Ejection Fraction

scientific article published on 15 June 2016

Prognostic benefit of beta-blockers in patients not receiving ACE-Inhibitors

scientific article

Prognostic impact of plasma N-terminal pro-brain natriuretic peptide in severe chronic congestive heart failure: a substudy of the Carvedilol Prospective Randomized Cumulative Survival (COPERNICUS) trial

scientific article published on 20 September 2004

Prognostic implications of left ventricular global longitudinal strain in heart failure patients with narrow QRS complex treated with cardiac resynchronization therapy: a subanalysis of the randomized EchoCRT trial

scientific article published in March 2017

Prophylaxis against atrial fibrillation after cardiac surgery: beneficial effect of perioperative metoprolol

scientific article published in March 2013

Protein kinases as cardiovascular therapeutic targets.

scientific article

Protein-bound uremic toxins: a long overlooked culprit in cardiorenal syndrome

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Quantifying the 3 Biases That Lead to Unintentional Overestimation of the Blood Pressure-Lowering Effect of Renal Denervation

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RAAS inhibitors and cardiovascular protection in large scale trials

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Radial artery pulse wave analysis for non-invasive assessment of coronary artery disease ⬇️

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Randomized double-blind trial of darbepoetin alfa in patients with symptomatic heart failure and anemia

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Rate of change in renal function and mortality in elderly treated hypertensive patients

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Rationale and design of ARTS: a randomized, double-blind study of BAY 94-8862 in patients with chronic heart failure and mild or moderate chronic kidney disease

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Rationale and design of MinerAlocorticoid Receptor antagonist Tolerability Study-Heart Failure (ARTS-HF): a randomized study of finerenone vs. eplerenone in patients who have worsening chronic heart failure with diabetes and/or chronic kidney diseas

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Rationale and design of the Eplerenone in Mild Patients Hospitalization And SurvIval Study in Heart Failure (EMPHASIS-HF).

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Rationale for a trial of low-dose aspirin for the primary prevention of major adverse cardiovascular events and vascular dementia in the elderly: Aspirin in Reducing Events in the Elderly (ASPREE)

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Rationale for and design of the TRUE-AHF trial: the effects of ularitide on the short-term clinical course and long-term mortality of patients with acute heart failure

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Rationale, design, and governance of Prospective Randomized Evaluation of Celecoxib Integrated Safety versus Ibuprofen Or Naproxen (PRECISION), a cardiovascular end point trial of nonsteroidal antiinflammatory agents in patients with arthritis

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Recent advances in the management of chronic heart failure

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Reduced exercise tolerance in CHF may be related to factors other than impaired skeletal muscle oxidative capacity.

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Relation of peripheral collagen markers to death and hospitalization in patients with heart failure and preserved ejection fraction: results of the I-PRESERVE collagen substudy

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Reliability of isokinetic strength and aerobic power testing for patients with chronic heart failure

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Renal Denervation and Hypertension ⬇️

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Renal Denervation in Human Hypertension: Mechanisms, Current Findings, and Future Prospects ⬇️

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Renal artery anatomy affects the blood pressure response to renal denervation in patients with resistant hypertension

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Renal denervation as a therapeutic approach for hypertension: novel implications for an old concept

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Renal denervation in moderate to severe CKD.

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Renal denervation: a potential new treatment modality for polycystic ovary syndrome?

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Renal denervation: current implications and future perspectives

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Renal hemodynamics and renal function after catheter-based renal sympathetic denervation in patients with resistant hypertension

scientific article published on 25 June 2012

Renal nerve ablation reduces augmentation index in patients with resistant hypertension

scientific article published in September 2013

Renal sympathetic denervation for the treatment of refractory hypertension

scientific article published on January 2014

Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial

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Renal sympathetic nerve ablation for treatment‐resistant hypertension ⬇️

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Renal sympathetic nerve ablation: the new frontier in the treatment of hypertension

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Renal sympathetic-nerve ablation for uncontrolled hypertension

scientific article published in August 2009

Renin-angiotensin blockade combined with natriuretic peptide system augmentation: novel therapeutic concepts to combat heart failure

scientific article published on May 2013

Response to Quality of Life After Renal Denervation ⬇️

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Role of renin in heart failure and therapeutic potential of direct renin inhibition

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Role of valsartan and other angiotensin receptor blocking agents in the management of cardiovascular disease

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Rural and urban differentials in primary care management of chronic heart failure: new data from the CASE study.

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SCReening Evaluation of the Evolution of New Heart Failure Study (SCREEN-HF): early detection of chronic heart failure in the workplace

scientific article published on 21 April 2016

Safety and Efficacy of Eplerenone in Patients at High Risk for Hyperkalemia and/or Worsening Renal Function

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Safety and efficacy of outpatient nesiritide in patients with advanced heart failure: results of the Second Follow-Up Serial Infusions of Nesiritide (FUSION II) trial

scientific article published in May 2008

Safety and tolerability of the novel non-steroidal mineralocorticoid receptor antagonist BAY 94-8862 in patients with chronic heart failure and mild or moderate chronic kidney disease: a randomized, double-blind trial

scientific article published on 27 May 2013

Selective cyclo-oxygenase-2 inhibitors and myocardial infarction: how strong is the link?

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Short- and long-term outcomes of intracoronary and endogenously mobilized bone marrow stem cells in the treatment of ST-segment elevation myocardial infarction: a meta-analysis of randomized control trials

scientific article published on 06 November 2011

Short- and long-term treatment of dilutional hyponatraemia with satavaptan, a selective arginine vasopressin V2-receptor antagonist: the DILIPO study

scientific article published on 03 January 2011

Short-term predictors of maintenance of normotension after withdrawal of antihypertensive drugs in the second Australian National Blood Pressure Study (ANBP2)

scientific article published on 01 January 2003

Should patients with chronic heart failure be treated with "statins"?

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Sleep apnea in heart failure increases heart rate variability and sympathetic dominance.

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Soluble epoxide hydrolase inhibition exerts beneficial anti-remodeling actions post-myocardial infarction

scientific article published on 10 January 2012

Standardizing care for acute decompensated heart failure in a large megatrial: the approach for the Acute Studies of Clinical Effectiveness of Nesiritide in Subjects with Decompensated Heart Failure (ASCEND-HF).

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Statins and chronic heart failure: do we need a large-scale outcome trial?

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Statins and clinical outcomes in heart failure

scientific article published on August 2007

Statins and symptomatic chronic systolic heart failure: a post-hoc analysis of 5010 patients enrolled in Val-HeFT

scientific article published on 17 October 2006

Substantial Reduction in Single Sympathetic Nerve Firing After Renal Denervation in Patients With Resistant Hypertension ⬇️

scientific article published on November 19, 2012

Sustained activation of microglia in the hypothalamic PVN following myocardial infarction.

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Sympatho-renal axis in chronic disease ⬇️

scientific article published on June 19, 2011

Systematic review of effect of coenzyme Q10 in physical exercise, hypertension and heart failure

scientific article published on January 2003

Systolic blood pressure variability is an important predictor of cardiovascular outcomes in elderly hypertensive patients

scientific article published in March 2014

Targeted anticytokine therapy in patients with chronic heart failure: results of the Randomized Etanercept Worldwide Evaluation (RENEWAL).

scientific article published on 15 March 2004

Targeting Fibrosis for the Treatment of Heart Failure: A Role for Transforming Growth Factor‐β ⬇️

scientific article published on September 23, 2010

Telemonitoring of fluid status in heart failure: CHAMPION ⬇️

scientific article published on February 19, 2011

Telephone support to rural and remote patients with heart failure: the Chronic Heart Failure Assessment by Telephone (CHAT) study.

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Tezosentan in patients with acute heart failure: design of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Study (VERITAS).

scientific article published in July 2005

The Aliskiren Trial to Minimize OutcomeS in Patients with HEart failure trial (ATMOSPHERE): revised statistical analysis plan and baseline characteristics.

scientific article published in October 2015

The Heartpod implantable heart failure therapy system

scientific article published on 9 November 2005

The Ongoing Evolution of Optimal Clinical Endpoints for Heart Failure Trials

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The Role of Renal Denervation in the Treatment of Heart Failure ⬇️

scientific article published on June 1, 2012

The Second Follow-up Serial Infusions of Nesiritide (FUSION II) trial for advanced heart failure: study rationale and design

scientific article published on April 2007

The Task Force for the diagnosis and treatment of chronic heart failure of the European Society of Cardiology. Guidelines for the diagnosis and treatment of chronic heart failure: full text (update 2005).

scientific article published on 4 October 2005

The acute haemodynamic effect of nebulised frusemide in stable, advanced heart failure

scientific article published on 13 April 2012

The black dog and the weak heart: comorbid depression in the patient with heart failure

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The cardiac (pro)renin receptor is primarily expressed in myocyte transverse tubules and is increased in experimental diabetic cardiomyopathy ⬇️

scientific article published on June 1, 2011

The cardiovascular safety of celecoxib

scientific article published on November 2005

The effect of QRS duration on cardiac resynchronization therapy in patients with a narrow QRS complex: a subgroup analysis of the EchoCRT trial

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The effects of eplerenone on length of stay and total days of heart failure hospitalization after myocardial infarction in patients with left ventricular systolic dysfunction

scientific article published in September 2009

The future of pharmacological therapy for heart failure

scientific article published on 15 April 2010

The impact of baseline HR and BP on the tolerability of carvedilol in the elderly: the COLA (Carvedilol Open Label Assessment) II Study

scientific article published on January 2006

The impact of eplerenone at different levels of risk in patients with systolic heart failure and mild symptoms: insight from a novel risk score for prognosis derived from the EMPHASIS-HF trial

scientific article published on 17 July 2013

The rationale and design of the Beta-blocker to LOwer CArdiovascular Dialysis Events (BLOCADE) Feasibility Study

scientific article published on 01 March 2015

The role of aldosterone receptor blockade in the management of cardiovascular disease

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The thrill of success: central arterial-venous anastomosis for hypertension

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The treatment gap in patients with chronic systolic heart failure: a systematic review of evidence-based prescribing in practice

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The uremic toxin adsorbent AST-120 abrogates cardiorenal injury following myocardial infarction

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The use of beta3-adrenergic receptor agonists in the treatment of heart failure

scientific article published on September 2009

The β-Blocker to Lower Cardiovascular Dialysis Events (BLOCADE) Feasibility Study: A Randomized Controlled Trial

scientific article published on 22 December 2015

Therapeutic potential of blockade of the urotensin II system in systemic hypertension

scientific article published on March 2007

To the heart of the matter: coxibs, smoking, and cardiovascular risk

scientific article published on 01 August 2005

Tolerability of beta-blockers in elderly patients with chronic heart failure: the COLA II study

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Tolerability of beta-blockers in heart failure: reassurance needed, reassurance provided

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Tolerability of carvedilol in heart failure: clinical trials experience

scientific article published on May 2004

Tranexamic acid in coronary artery surgery: One-year results of the Aspirin and Tranexamic Acid for Coronary Artery Surgery (ATACAS) trial

scientific article published on 19 October 2018

Tranilast attenuates cardiac matrix deposition in experimental diabetes: role of transforming growth factor-beta

scientific article published in February 2005

Tranilast attenuates diastolic dysfunction and structural injury in experimental diabetic cardiomyopathy

scientific article published on 24 August 2007

Tumor necrosis factor-alpha blockade as a therapeutic strategy in heart failure (RENEWAL and ATTACH): unsuccessful, to be specific

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Updated meta-analysis on antithrombotic therapy in patients with heart failure and sinus rhythm

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Urotensin II Levels Are an Important Marker for the Severity of Portal Hypertension in Children ⬇️

scientific article published on July 1, 2011

Urotensin II in chronic liver disease: in vivo effect on vascular tone

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Urotensin II modulates hepatic fibrosis and portal hemodynamic alterations in rats

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Urotensin II: a novel vasoactive mediator linked to chronic liver disease and portal hypertension

scientific article published on November 2007

Urotensin II: a vascular mediator in health and disease

scientific article published on 01 April 2005

Urotensin-II as a novel therapeutic target in the clinical management of cardiorenal disease.

scientific article published on March 2004

Using adult stem cells to treat heart failure--fact or fiction?

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Utility of B-type natriuretic peptide as a screen for left ventricular dysfunction in patients with diabetes: response to Epshteyn et al

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What is the methodological and reporting quality of health related quality of life in chronic heart failure clinical trials?

scientific article published on 05 February 2012

Why did high-dose rosuvastatin not improve cardiac remodeling in chronic heart failure? Mechanistic insights from the UNIVERSE study

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Why do phase III trials of promising heart failure drugs often fail? the contribution of “regression to the truth” ⬇️

scientific article published on October 1, 2003

Worsening heart failure, a critical event during hospital admission for acute heart failure: results from the VERITAS study

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Worsening renal function during renin-angiotensin-aldosterone system inhibitor initiation and long-term outcomes in patients with left ventricular systolic dysfunction

scientific article published on 11 December 2013

p38 mitogen-activated protein kinase inhibition improves cardiac function and attenuates left ventricular remodeling following myocardial infarction in the rat

scientific article published on 01 October 2004

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