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List of works by Osvalds Pugovics

A short-term high-dose administration of sodium pivalate impairs pyruvate metabolism without affecting cardiac function

scientific article published on 01 December 2012

Activated peroxisomal fatty acid metabolism improves cardiac recovery in ischemia-reperfusion

scientific article published on 26 March 2013

Determination of trimethylamine-N-oxide in combination with L-carnitine and γ-butyrobetaine in human plasma by UPLC/MS/MS.

scientific article published on 14 April 2015

Diabetes is Associated with Higher Trimethylamine N-oxide Plasma Levels.

scientific article

Effects of long-term mildronate treatment on cardiac and liver functions in rats.

scientific article published on 5 August 2009

Effects of the N-methyl-d-aspartate receptor antagonist, MK-801, on spatial memory and influence of the route of administration

scientific article published on 02 July 2019

Efficacy of Proanthocyanidins from Root Extract in Reducing Viability While Preserving Oral Commensal

scientific article published on 22 August 2018

Expression and purification of active, stabilized trimethyllysine hydroxylase.

scientific article

High l-carnitine concentrations do not prevent late diabetic complications in type 1 and 2 diabetic patients ⬇️

scientific article published on April 25, 2012

Inhibition of L-carnitine biosynthesis and transport by methyl-γ-butyrobetaine decreases fatty acid oxidation and protects against myocardial infarction

scientific article published on 12 January 2015

L-Carnitine Supplementation Increases Trimethylamine-N-Oxide but not Markers of Atherosclerosis in Healthy Aged Women

scientific article published on 28 November 2018

Long-chain acylcarnitine content determines the pattern of energy metabolism in cardiac mitochondria.

scientific article published on 31 May 2014

Mildronate decreases carnitine availability and up-regulates glucose uptake and related gene expression in the mouse heart.

scientific article

Mildronate treatment alters γ-butyrobetaine and l-carnitine concentrations in healthy volunteers.

scientific article published on 6 July 2011

Mildronate treatment improves functional recovery following middle cerebral artery occlusion in rats

scientific article published on 21 March 2011

Mildronate, the inhibitor of L-carnitine transport, induces brain mitochondrial uncoupling and protects against anoxia-reoxygenation.

scientific article published on 12 December 2013

Plasma acylcarnitine concentrations reflect the acylcarnitine profile in cardiac tissues

scientific article published on 13 December 2017

Quantitative analysis of phenibut in rat brain tissue extracts by liquid chromatography-tandem mass spectrometry.

scientific article

Selective inhibition of OCTN2 is more effective than inhibition of gamma-butyrobetaine dioxygenase to decrease the availability of l-carnitine and to reduce myocardial infarct size.

scientific article published on 14 May 2014

Single nucleotide polymorphisms in the intergenic region between metformin transporter OCT2 and OCT3 coding genes are associated with short-term response to metformin monotherapy in type 2 diabetes mellitus patients

scientific article published on 8 September 2016

Suppression of intestinal microbiota-dependent production of pro-atherogenic trimethylamine N-oxide by shifting L-carnitine microbial degradation.

scientific article

The Cardioprotective Effect of Mildronate is Diminished After Co-Treatment With l-Carnitine ⬇️

scientific article published on September 8, 2011

The heart is better protected against myocardial infarction in the fed state compared to the fasted state.

scientific article published on 18 October 2013

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