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List of works by Azzeddine Dakhama

Activation of naturally occurring lung CD4(+)CD25(+) regulatory T cells requires CD8 and MHC I interaction

scholarly article

Airway hyperresponsiveness in the absence of CD4+ T cells after primary but not secondary challenge

scientific article published on 21 April 2005

Allergen-specific early neutrophil infiltration after allergen challenge in a murine model

scientific article

Alteration of airway neuropeptide expression and development of airway hyperresponsiveness following respiratory syncytial virus infection

scientific article published on 17 December 2004

CD8 regulates T regulatory cell production of IL-6 and maintains their suppressive phenotype in allergic lung disease

scientific article

CD8+ T cell-mediated airway hyperresponsiveness and inflammation is dependent on CD4+IL-4+ T cells

scientific article published on 01 September 2007

CD8+ T lymphocytes and leukotriene B4: novel interactions in the persistence and progression of asthma

scientific article

Calcitonin gene-related peptide: role in airway homeostasis

scientific article published on June 2004

Complement activation is critical to airway hyperresponsiveness after acute ozone exposure

scientific article

Contribution of allergen-specific and nonspecific nasal responses to early-phase and late-phase nasal responses

scientific article published on 21 December 2007

Contribution of antigen-primed CD8+ T cells to the development of airway hyperresponsiveness and inflammation is associated with IL-13.

scientific article published in February 2004

Corticosteroids enhance CD8+ T cell-mediated airway hyperresponsiveness and allergic inflammation by upregulating leukotriene B4 receptor 1.

scientific article published in April 2008

Critical role of the Fc receptor gamma-chain on APCs in the development of allergen-induced airway hyperresponsiveness and inflammation

scientific article published on 01 January 2007

Cytosolic phospholipase A2 contributes to innate immune defense against Candida albicans lung infection

scientific article

Differential effects of dendritic cell transfer on airway hyperresponsiveness and inflammation

scientific article published on 16 January 2009

Effect of microbial heat shock proteins on airway inflammation and hyperresponsiveness

scientific article published in November 2002

Effector CD8+ T cells mediate inflammation and airway hyper-responsiveness

scientific article published on 18 July 2004

Effects of anti-g and anti-f antibodies on airway function after respiratory syncytial virus infection

scientific article

Essential role of Notch signaling in effector memory CD8+ T cell-mediated airway hyperresponsiveness and inflammation.

scientific article published on 21 April 2008

Estrogen determines sex differences in airway responsiveness after allergen exposure

scientific article published on 6 December 2007

Factor B of the alternative complement pathway regulates development of airway hyperresponsiveness and inflammation

scholarly article

Human IL-32 expression protects mice against a hypervirulent strain of Mycobacterium tuberculosis

scientific article published on 27 March 2015

IFN-gamma production during initial infection determines the outcome of reinfection with respiratory syncytial virus

scientific article

IL-10-treated dendritic cells decrease airway hyperresponsiveness and airway inflammation in mice

scientific article published on 13 March 2007

IL-2 and IL-18 attenuation of airway hyperresponsiveness requires STAT4, IFN-gamma, and natural killer cells

scientific article published on 12 October 2006

Importance of myeloid dendritic cells in persistent airway disease after repeated allergen exposure

scientific article published on 28 September 2005

In Vivo Assessment of Airway Function in the Mouse Model

scientific article published in January 2016

Induction and maintenance of airway responsiveness to allergen challenge are determined at the age of initial sensitization

scientific article published in July 2004

Induction of Regulated upon Activation, Normal T Cells Expressed and Secreted (RANTES) and Transforming Growth Factor-β1 in Airway Epithelial Cells by Mycoplasma pneumoniae

scientific article published on April 24, 2003

Inhibition of Complement Activation Decreases Airway Inflammation and Hyperresponsiveness

scientific article published on September 18, 2003

Inhibition of early airway neutrophilia does not affect development of airway hyperresponsiveness

scientific article published on 23 January 2004

Inhibition of spleen tyrosine kinase prevents mast cell activation and airway hyperresponsiveness

scientific article published on 28 September 2005

Insights into the pathogenesis of asthma utilizing murine models

scientific article published on 17 September 2004

Interleukin-1 receptor antagonist attenuates airway hyperresponsiveness following exposure to ozone

scientific article published on 30 January 2004

Interleukin-1 receptor-associated kinase M (IRAK-M) promotes human rhinovirus infection in lung epithelial cells via the autophagic pathway

scientific article published on 30 August 2013

JNK2 regulates the functional plasticity of naturally occurring T regulatory cells and the enhancement of lung allergic responses

scientific article

Leukotriene B4 receptor 1 expression on dendritic cells is required for the development of Th2 responses and allergen-induced airway hyperresponsiveness

scientific article

Leukotriene B4 receptor 1 is differentially expressed on peripheral T cells of steroid-sensitive and -resistant asthmatics

scientific article published on 07 January 2014

Leukotriene B4 receptor-1 is essential for allergen-mediated recruitment of CD8+ T cells and airway hyperresponsiveness

scientific article published on 01 April 2005

Leukotriene B4 release from mast cells in IgE-mediated airway hyperresponsiveness and inflammation

scientific article

Loss of T Regulatory Cell Suppression following Signaling through Glucocorticoid-induced Tumor Necrosis Receptor (GITR) Is Dependent on c-Jun N-terminal Kinase Activation

scientific article published on March 29, 2012

MEF2C regulates c‐Jun but not TNF‐α gene expression in stimulated mast cells

scientific article published on October 1, 2003

Mast cells, Fc epsilon RI, and IL-13 are required for development of airway hyperresponsiveness after aerosolized allergen exposure in the absence of adjuvant

scientific article published in May 2004

Mechanisms determining cholinergic neural responses in airways of young and mature rabbits

scientific article

Migration and accumulation of eosinophils toward regional lymph nodes after airway allergen challenge

scientific article published on 01 October 2004

Mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2-dependent pathways are essential for CD8+ T cell-mediated airway hyperresponsiveness and inflammation.

scientific article

Modulation of airway responses by prostaglandins in young and fully grown rabbits.

scientific article

Montelukast during primary infection prevents airway hyperresponsiveness and inflammation after reinfection with respiratory syncytial virus

scientific article

Naturally occurring lung CD4(+)CD25(+) T cell regulation of airway allergic responses depends on IL-10 induction of TGF-beta.

scientific article published in February 2007

Neuropeptide release from airways of young and fully-grown rabbits

scientific article published in December 2006

New insights into asthma pathogenesis and treatment

scientific article published on 11 August 2011

Peanut-induced intestinal allergy is mediated through a mast cell-IgE-FcepsilonRI-IL-13 pathway

scientific article

Phosphodiesterase IV and neutral endopeptidase in airways from developing and allergen sensitized rabbits

scientific article published on 20 October 2005

Plasticity of invariant NKT cell regulation of allergic airway disease is dependent on IFN-gamma production

scientific article published on 4 June 2010

Plasticity of regulatory T cells: subversion of suppressive function and conversion to enhancement of lung allergic responses

scientific article published on 01 June 2008

Prior airway exposure to allergen increases virus-induced airway hyperresponsiveness.

scientific article published in November 2003

Pulmonary surfactant phosphatidylglycerol inhibits respiratory syncytial virus-induced inflammation and infection

scientific article

Regulation of airway hyperresponsiveness by calcitonin gene-related peptide in allergen sensitized and challenged mice

scientific article published in April 2002

Requirement for leukotriene B4 receptor 1 in allergen-induced airway hyperresponsiveness

scientific article (publication date: 15 July 2005)

Requirement for the p75 TNF-alpha receptor 2 in the regulation of airway hyperresponsiveness by gamma delta T cells

scientific article published in October 2002

Respiratory syncytial virus-induced airway hyperresponsiveness is independent of IL-13 compared with that induced by allergen.

scientific article

Responsiveness to respiratory syncytial virus in neonates is mediated through thymic stromal lymphopoietin and OX40 ligand

scientific article published on October 1, 2012

Spontaneous airway hyperresponsiveness in estrogen receptor-alpha-deficient mice

scientific article published on 9 November 2006

Surfactant protein D regulates airway function and allergic inflammation through modulation of macrophage function

scientific article published on 25 July 2003

The G glycoprotein of respiratory syncytial virus depresses respiratory rates through the CX3C motif and substance P.

scientific article

The effect of BPIFA1/SPLUNC1 genetic variation on its expression and function in asthmatic airway epithelium.

scientific article published on 18 April 2019

The enhancement or prevention of airway hyperresponsiveness during reinfection with respiratory syncytial virus is critically dependent on the age at first infection and IL-13 production

scientific article

The failure of interleukin-10-deficient mice to develop airway hyperresponsiveness is overcome by respiratory syncytial virus infection in allergen-sensitized/challenged mice

scientific article published in March 2002

The leukotriene B4 receptor (BLT1) is required for effector CD8+ T cell-mediated, mast cell-dependent airway hyperresponsiveness.

scientific article

The lung response to ozone is determined by age and is partially dependent on toll-Like receptor 4.

scientific article

The role of IL-13 in established allergic airway disease

scientific article published in December 2002

The role of virus-specific immunoglobulin E in airway hyperresponsiveness

scientific article

Transcriptome profiling of the newborn mouse lung response to acute ozone exposure

scientific article published on 12 December 2013

Transient neutrophil infiltration after allergen challenge is dependent on specific antibodies and Fc gamma III receptors.

scientific article published in April 2003

Vaccine-induced CD8+ T cell-dependent suppression of airway hyperresponsiveness and inflammation.

scientific article published in July 2009

Vgamma1+ T cells and tumor necrosis factor-alpha in ozone-induced airway hyperresponsiveness

scientific article

Virus-induced airway dysfunction: pathogenesis and biomechanisms

scientific article

Virus-specific IgE enhances airway responsiveness on reinfection with respiratory syncytial virus in newborn mice

scientific article published on 3 December 2008