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List of works by Erwin W. Gelfand

1,25D3 prevents CD8(+)Tc2 skewing and asthma development through VDR binding changes to the Cyp11a1 promoter

scientific article

A Novel Prostacyclin Agonist Protects against Airway Hyperresponsiveness and Remodeling in Mice ⬇️

scientific article published on March 8, 2012

A Toddler With Rash, Encephalopathy, and Hemolytic Anemia

scientific article

A comparison of the clinical characteristics of children and adults with severe asthma

scientific article

A focus on the asthma HEDIS measure and its implications for clinical practice.

scientific article

A novel mutation in NFKBIA/IKBA results in a degradation-resistant N-truncated protein and is associated with ectodermal dysplasia with immunodeficiency

scientific article

A novel mutation of intron 22 in Janus kinase 3-deficient severe combined immunodeficiency

scientific article published on 16 April 2007

A randomized trial to test the effectiveness of art therapy for children with asthma

scientific article published on 11 May 2010

A study of health effect estimates using competing methods to model personal exposures to ambient PM2.5

scientific article published on 16 May 2007

Activation of MAP2-kinase in B lymphocytes by calcium ionophores.

scientific article published on December 1994

Activation of Na+/H+ exchange and the expression of cellular proto-oncogenes in mitogen- and phorbol ester-treated lymphocytes

scientific article

Activation of human monocytes via a non-neurokinin substance P receptor that is coupled to Gi protein, calcium, phospholipase D, MAP kinase, and IL-6 production

scientific article published on 01 October 1994

Activation of human thymocytes after infection by EBV

scientific article published on 01 February 1995

Activation of naturally occurring lung CD4(+)CD25(+) regulatory T cells requires CD8 and MHC I interaction

scholarly article

Activation of the Na+/H+ antiport is not required for lectin-induced proliferation of human T lymphocytes

scientific article published on 01 February 1986

Acute infectious mononucleosis stimulates the selective expression/expansion of V beta 6.1-3 and V beta 7 T cells

scientific article published on 01 March 1993

Adoptive transfer of T cells induces airway hyperresponsiveness independently of airway eosinophilia but in a signal transducer and activator of transcription 6-dependent manner

scientific article published on 01 May 2002

Advances in therapy for adult asthma

scientific article published on January 2008

Aerosolized anti-T-cell-receptor antibodies are effective against airway inflammation and hyperreactivity

scientific article published on 25 March 2004

Aerosolized antigen exposure without adjuvant causes increased IgE production and increased airway responsiveness in the mouse

scientific article

Aggregation of the FcepsilonRI on mast cells stimulates c-Jun amino-terminal kinase activity. A response inhibited by wortmannin

scientific article published on May 1996

Airway hyperresponsiveness in the absence of CD4+ T cells after primary but not secondary challenge

scientific article published on 21 April 2005

Airway hyperresponsiveness through synergy of gammadelta} T cells and NKT cells

scientific article published on September 2007

Allergen-specific IgE and IL-5 are essential for the development of airway hyperresponsiveness

scientific article published on 01 June 1997

Allergen-specific early neutrophil infiltration after allergen challenge in a murine model

scientific article

Allergic airway hyperresponsiveness-enhancing gammadelta T cells develop in normal untreated mice and fail to produce IL-4/13, unlike Th2 and NKT cells

scientific article published on February 2009

Alteration of airway neuropeptide expression and development of airway hyperresponsiveness following respiratory syncytial virus infection

scientific article published on 17 December 2004

An ELISA spot assay for quantitation of human immunoglobulin-secreting cells

scientific article published in August 1991

Animal models of airway sensitization.

scientific article published in November 2007

Antagonistic effects of calcium ionophores and phorbol esters on T cell receptor mRNA levels in human thymocytes

scientific article published on 01 January 1988

Anti-CD86 (B7.2) treatment abolishes allergic airway hyperresponsiveness in mice

scientific article published on 01 May 1999

Anti-inflammatory activity of H1-receptor antagonists: review of recent experimental research

scientific article published on January 2004

Anti-interleukin 5 but not anti-IgE prevents airway inflammation and airway hyperresponsiveness

scientific article published on 01 September 1999

Antigen-dependent increase in cytosolic free calcium in specific human T-lymphocyte clones

scientific article

Antigen-dependent regulation of IgE antibody production by human antigen-specific B cells

scientific article published on 01 December 1996

Antigen-specific and -nonspecific mitogenic signals in the activation of human T cell clones

scientific article published on 01 June 1987

Antigen-specific immunoglobulin-A prevents increased airway responsiveness and lung eosinophilia after airway challenge in sensitized mice

scientific article published in August 1998

Antiinterleukin-5 antibody prevents airway hyperresponsiveness in a murine model of airway sensitization

scientific article published on 01 March 1997

Are all IGIVs the same?

scientific article published on 01 December 2002

Arhgef1 is required by T cells for the development of airway hyperreactivity and inflammation

scientific article

Asymmetric DDE (D35E)-like sequences in the RAG proteins: implications for V(D)J recombination and retroviral pathogenesis

scientific article published on 01 June 1999

Autocrine stimulation of B lymphocytes by a platelet-activating factor receptor agonist, 1-palmitoyl-2-acetyl-sn-glycero-3-phosphocholine

scientific article published on 01 January 1994

Biallelic mutations in DNA ligase 1 underlie a spectrum of immune deficiencies

scientific article published on 05 November 2018

Blocking the Leukotriene B4 Receptor 1 Inhibits Late-Phase Airway Responses in Established Disease ⬇️

scientific article published on March 18, 2011

CD23 deficient mice develop allergic airway hyperresponsiveness following sensitization with ovalbumin

scientific article published on 01 December 1997

CD23 exhibits negative regulatory effects on allergic sensitization and airway hyperresponsiveness

scientific article published on 01 March 2000

CD8 T cells are essential in the development of respiratory syncytial virus-induced lung eosinophilia and airway hyperresponsiveness

scientific article published in April 1999

CD8 regulates T regulatory cell production of IL-6 and maintains their suppressive phenotype in allergic lung disease

scientific article

CD8+ T cell-mediated airway hyperresponsiveness and inflammation is dependent on CD4+IL-4+ T cells

scientific article published on 01 September 2007

CD8+ T lymphocytes and leukotriene B4: novel interactions in the persistence and progression of asthma

scientific article

Calcitonin gene-related peptide: role in airway homeostasis

scientific article published on June 2004

Calcium-dependent intracellular acidification dominates the pH response to mitogen in human T cells

scientific article published on 01 January 1988

Characterization of the activation of Na+/H+ exchange in lymphocytes by phorbol esters: change in cytoplasmic pH dependence of the antiport

scientific article published on March 1985

Characterization of the requirements for human T cell mitogenesis by using suboptimal concentrations of phytohemagglutinin

scientific article published on 01 November 1985

Characterization of the role for calcium influx in mitogen-induced triggering of human T cells. Identification of calcium-dependent and calcium-independent signals

scientific article published on 01 August 1986

Coding-region alterations in BTK do not universally cause X-linked agammaglobulinemia

scientific article

Common Variable Immunodeficiency

scientific article (publication date: November 2015)

Comparison of phorbol ester/calcium ionophore and phytohemagglutinin-induced signaling in human T lymphocytes. Demonstration of interleukin 2-independent transferrin receptor gene expression

scientific article published on 01 January 1988

Comparison of the allergenicity of ovalbumin and ovalbumin peptide 323-339. Differential expansion of V beta-expressing T cell populations.

scientific article

Complement activation is critical to airway hyperresponsiveness after acute ozone exposure

scientific article

Contrasting roles for the receptor for advanced glycation end-products on structural cells in allergic airway inflammation vs. airway hyperresponsiveness

scientific article

Contribution of allergen-specific and nonspecific nasal responses to early-phase and late-phase nasal responses

scientific article published on 21 December 2007

Contribution of antigen-primed CD8+ T cells to the development of airway hyperresponsiveness and inflammation is associated with IL-13.

scientific article published in February 2004

Control of cell cycle entry and progression in mitogen-stimulated human B lymphocytes

scientific article published on 01 February 1995

Controversies in IgG replacement therapy in patients with antibody deficiency diseases

scientific article published on April 2013

Corrigendum: Germline hypomorphic CARD11 mutations in severe atopic disease

scientific article published in October 2017

Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids

scientific article

Corticosteroids enhance CD8+ T cell-mediated airway hyperresponsiveness and allergic inflammation by upregulating leukotriene B4 receptor 1.

scientific article published in April 2008

Cost savings from intravenous immunoglobulin manufactured from chromotography/caprylate (IGIV-C) in persons with primary humoral immunodeficiency disorder

scientific article published in July 2005

Critical decisions in selecting an intravenous immunoglobulin product

scientific article published on 01 November 2005

Critical role of the Fc receptor gamma-chain on APCs in the development of allergen-induced airway hyperresponsiveness and inflammation

scientific article published on 01 January 2007

Critical roles for interleukin-4 and interleukin-5 during respiratory syncytial virus infection in the development of airway hyperresponsiveness after airway sensitization

scientific article published in August 2000

Cyclin-dependent kinase 6 inhibits proliferation of human mammary epithelial cells

scientific article

Cyclosporin A inhibits initiation but not progression of human T cell proliferation triggered by phorbol esters and calcium ionophores

scientific article published on 01 December 1988

Cysteinyl Leukotriene Receptor 1 and Health Effects of Particulate Exposure in Asthma

article

Cystic fibrosis 3849+10kb C > T mutation associated with severe pulmonary disease and male fertility

scientific article published on 01 February 1996

Deferoxamine: a reversible S-phase inhibitor of human lymphocyte proliferation

scientific article published on 01 September 1984

Definition of the roles for iron and essential fatty acids in cell cycle progression of normal human T lymphocytes

scientific article published on 01 February 1993

Development of asthma is determined by the age-dependent host response to respiratory virus infection: therapeutic implications ⬇️

scientific article published on September 13, 2012

Development of eosinophilic airway inflammation and airway hyperresponsiveness requires interleukin-5 but not immunoglobulin E or B lymphocytes

scientific article published on 01 October 1999

Diagnosis and evaluation of primary panhypogammaglobulinemia: A molecular and genetic challenge ⬇️

scientific article published on June 1, 2013

Differences between IGIV products: impact on clinical outcome

scientific article

Different potentials of gamma delta T cell subsets in regulating airway responsiveness: V gamma 1+ cells, but not V gamma 4+ cells, promote airway hyperreactivity, Th2 cytokines, and airway inflammation

scientific article published in March 2004

Differential activation and regulation of mitogen-activated protein kinases through the antigen receptor and CD40 in human B cells

scientific article published on September 1999

Differential activation of p21ras in CD45RA+ and CD45RO+ human T lymphocytes

scientific article published on 01 March 1994

Differential effects of dendritic cell transfer on airway hyperresponsiveness and inflammation

scientific article published on 16 January 2009

Differential expression of CD40 ligand on T cell subsets. Implications for different roles of CD45RA+ and CD45RO+ cells in IgE production

scientific article published on 01 March 1996

Differential inhibition of T and B cell function in IL-4-dependent IgE production by cyclosporin A and methylprednisolone

scientific article published on 01 December 1990

Differential regulation of CD40-mediated human B cell responses by antibodies directed against different CD40 epitopes

scientific article published on 01 May 2000

Differential regulation of the synthesis and activity of the major cyclin‐dependent kinases, p34cdc2, p33cdk2, and p34cdk4, during cell cycle entry and progression in normal human T lymphocytes ⬇️

scientific article published on 01 November 1995

Differential regulation of the tumor suppressor molecules, retinoblastoma susceptibility gene product (Rb) and p53, during cell cycle progression of normal human T cells

scientific article

Differential requirements for interleukin-2 distinguish the expression and activity of the cyclin-dependent kinases Cdk4 and Cdk2 in human T cells

scientific article published on 01 December 1994

Dissociation of unidirectional influx of external Ca2+ and release from internal stores in activated human T lymphocytes

scientific article published on 01 June 1990

Distribution and leukocyte contacts of gammadelta T cells in the lung

scientific article published on 4 October 2005

Do NHLBI lung function criteria apply to children? A cross-sectional evaluation of childhood asthma at National Jewish Medical and Research Center, 1999-2002

scientific article published on 01 April 2005

Dominant-negative loss of function arises from a second, more frequent variant within the SAND domain of autoimmune regulator (AIRE).

scientific article published on 9 November 2017

ERK1 is important for Th2 differentiation and development of experimental asthma

scientific article published on 18 January 2012

Effect of chemically modified IL-13 short interfering RNA on development of airway hyperresponsiveness in mice

scientific article

Effect of deferoxamine on DNA synthesis, DNA repair, cell proliferation, and differentiation of HL-60 cells

scientific article published on 01 May 1987

Effect of microbial heat shock proteins on airway inflammation and hyperresponsiveness

scientific article published in November 2002

Effect of the inhaled corticosteroid mometasone on small airway patency in patients with asthma.

scientific article published in May 2009

Effector CD8+ T cells mediate inflammation and airway hyper-responsiveness

scientific article published on 18 July 2004

Effects of agents that inhibit cellular iron incorporation on bladder cancer cell proliferation.

scientific article published in September 1993

Effects of anti-g and anti-f antibodies on airway function after respiratory syncytial virus infection

scientific article

Effects of fexofenadine on T-cell function in a murine model of allergen-induced airway inflammation and hyperresponsiveness ⬇️

scientific article published on October 1, 2003

Effects of iron-depletion on cell cycle progression in normal human T lymphocytes: selective inhibition of the appearance of the cyclin A-associated component of the p33cdk2 kinase ⬇️

scientific article published on September 15, 1995

Effects of wintertime ambient air pollutants on asthma exacerbations in urban minority children with moderate to severe disease

scientific article

Emphysema requires the receptor for advanced glycation end-products triggering on structural cells

scientific article

Eosinophils contribute to the resolution of lung-allergic responses following repeated allergen challenge

scientific article

Eotaxin-1-Deficient Mice Develop Airway Eosinophilia and Airway Hyperresponsiveness ⬇️

scientific article published on October 1, 2001

Epstein-Barr virus replicative gene transcription during de novo infection of human thymocytes: simultaneous early expression of BZLF-1 and its repressor RAZ.

scientific article

Essential role of Notch signaling in effector memory CD8+ T cell-mediated airway hyperresponsiveness and inflammation.

scientific article published on 21 April 2008

Estimating effects of ambient PM2.5 exposure on health using PM2.5 component measurements and regression calibration

scientific article published on 01 January 2006

Estrogen determines sex differences in airway responsiveness after allergen exposure

scientific article published on 6 December 2007

Evidence for active purine nucleoside cycles in human mononuclear cells and cultured fibroblasts

scientific article published on 01 October 1982

Evidence that CD8+ dendritic cells enable the development of gammadelta T cells that modulate airway hyperresponsiveness

scientific article published on July 2008

Expansion of B lymphocytes with an unusual immunoglobulin rearrangement associated with atypical lymphocytosis and cigarette smoking

scientific article published in June 1990

Experimentally manipulated sleep duration in adolescents with asthma: Feasibility and preliminary findings

scientific article published on 14 April 2015

Exposure to tobacco smoke increases leukotriene E4-related albuterol usage and response to montelukast.

scientific article published on 25 April 2008

Expression and activation of the steroidogenic enzyme CYP11A1 is associated with IL-13 production in T cells from peanut allergic children

scientific article published on 04 June 2020

Expression of functional activating and inhibitory Fcgamma receptors on human B cells

scientific article published on 17 February 2004

Factor B of the alternative complement pathway regulates development of airway hyperresponsiveness and inflammation

scholarly article

Failure of rapamycin to block proliferation once resting cells have entered the cell cycle despite inactivation of p70 S6 kinase

scientific article

Fexofenadine modulates T-cell function, preventing allergen-induced airway inflammation and hyperresponsiveness

scientific article

First do no harm: managing antihistamine impairment in patients with allergic rhinitis.

scientific article

Fluctuations in quality of life and immune responses during intravenous immunoglobulin infusion cycles

scientific article published on 22 March 2022

Forkhead box protein 3 demethylation is associated with tolerance induction in peanut-induced intestinal allergy

scientific article published on 4 May 2017

Functional characterization of human thymocyte subpopulations separated by density gradient centrifugation.

scientific article

Functional thrombin receptors on human T lymphoblastoid cells.

scientific article

Germline hypomorphic CARD11 mutations in severe atopic disease

scientific article published on 19 June 2017

Growth and characterization of T cell colonies from human thymus.

scientific article

Growth factors temporally associate with airway responsiveness and inflammation in allergen-exposed mice

scientific article published on 14 November 2007

Hematopoietic stem cell transplantation in 29 patients hemizygous for hypomorphic IKBKG / NEMO mutations.

scientific article published on 5 July 2017

Hepatocyte growth factor attenuates airway hyperresponsiveness, inflammation, and remodeling

scientific article published on 30 December 2004

Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis

scientific article published on 22 August 2019

Heterozygous IKKβ Activation Loop Mutation Results in a Complex Immunodeficiency Syndrome

scientific article published on 15 June 2020

Histopathology of severe childhood asthma: a case series

scientific article published in July 2003

Human CD45RA+ and CD45R0+ T cells exhibit similar CD3/T cell receptor-mediated transmembrane signaling capacities but differ in response to co-stimulatory signals

scientific article published on 01 June 1994

Human T cell colony formation in microculture: analysis of growth requirements and functional activities.

scientific article

Hypoxia enhances CD8+ TC2 cell-dependent airway hyperresponsiveness and inflammation through hypoxia-inducible factor 1α.

scientific article published on 17 January 2019

IFN-gamma production during initial infection determines the outcome of reinfection with respiratory syncytial virus

scientific article

IKBKG (nuclear factor-kappa B essential modulator) mutation can be associated with opportunistic infection without impairing Toll-like receptor function

scientific article

IL-10-treated dendritic cells decrease airway hyperresponsiveness and airway inflammation in mice

scientific article published on 13 March 2007

IL-13 is essential to the late-phase response in allergic rhinitis

scientific article published on 7 August 2006

IL-17A is essential to the development of elastase-induced pulmonary inflammation and emphysema in mice

scientific article published on 20 January 2013

IL-2 and IL-18 attenuation of airway hyperresponsiveness requires STAT4, IFN-gamma, and natural killer cells

scientific article published on 12 October 2006

IL-23 Is Essential for the Development of Elastase-Induced Pulmonary Inflammation and Emphysema

scientific article published on 28 June 2016

IL-4-dependent up-regulation of IL-4 receptor expression in murine T and B cells

scientific article

IL-5 and eosinophils are essential for the development of airway hyperresponsiveness following acute respiratory syncytial virus infection

scientific article published in March 1999

Identification of multiple cell cycle regulatory functions of p57Kip2 in human T lymphocytes

scientific article published on August 2004

Immunoglobulin gene rearrangement in acute myelogenous leukemia

scientific article published on 01 October 1984

Immunoglobulin replacement therapy in primary antibody deficiency diseases--maximizing success

scientific article

Immunomodulatory Effects of Ambroxol on Airway Hyperresponsiveness and Inflammation

scientific article published on 17 June 2016

Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice.

scientific article

Importance of myeloid dendritic cells in persistent airway disease after repeated allergen exposure

scientific article published on 28 September 2005

Importance of the leukotriene B4-BLT1 and LTB4-BLT2 pathways in asthma

scientific article published in October 2017

Importance of the personal endotoxin cloud in school-age children with asthma

scientific article

In Vivo Assessment of Airway Function in the Mouse Model

scientific article published in January 2016

In vitro and in vivo effects of deferoxamine in neonatal acute leukemia

scientific article published on 01 March 1987

Inactivation of NF-kappaB by EBV BZLF-1-encoded ZEBRA protein in human T cells

scientific article published on 01 December 1999

Increase in cytosolic free calcium concentration is an intracellular messenger for the production of interleukin 2 but not for expression of the interleukin 2 receptor.

scientific article

Increased airways responsiveness in mice depends on local challenge with antigen

scientific article published on January 1994

Increased cyclic adenosine monophosphate levels block progression but not initiation of human T cell proliferation

scientific article published in July 1990

Inducible and naturally occurring regulatory T cells enhance lung allergic responses through divergent transcriptional pathways

scientific article published on 16 August 2016

Induction and maintenance of airway responsiveness to allergen challenge are determined at the age of initial sensitization

scientific article published in July 2004

Induction of Regulated upon Activation, Normal T Cells Expressed and Secreted (RANTES) and Transforming Growth Factor-β1 in Airway Epithelial Cells by Mycoplasma pneumoniae ⬇️

scientific article published on April 24, 2003

Induction of competence and progression signals in human T lymphocytes by phorbol esters and calcium ionophores

scientific article published on 01 November 1988

Induction of human B cell proliferation and differentiation by the combination of phorbol ester and ionomycin

scientific article published on 01 May 1987

Inflammatory mediators in allergic rhinitis

scientific article

Inhibition of Complement Activation Decreases Airway Inflammation and Hyperresponsiveness ⬇️

scientific article published on September 18, 2003

Inhibition of IgE production and normalization of airways responsiveness by sensitized CD8 T cells in a mouse model of allergen-induced sensitization

scientific article published on 01 January 1994

Inhibition of Pim1 Kinase Activation Attenuates Allergen-Induced Airway Hyperresponsiveness and Inflammation ⬇️

scientific article published on November 10, 2011

Inhibition of Pim1 kinase prevents peanut allergy by enhancing Runx3 expression and suppressing TH2 and TH17 T-cell differentiation ⬇️

scientific article published on September 1, 2012

Inhibition of early airway neutrophilia does not affect development of airway hyperresponsiveness

scientific article published on 23 January 2004

Inhibition of neutrophil elastase attenuates airway hyperresponsiveness and inflammation in a mouse model of secondary allergen challenge: neutrophil elastase inhibition attenuates allergic airway responses ⬇️

scientific article published on January 24, 2013

Inhibition of phosphodiesterase 4 attenuates airway hyperresponsiveness and airway inflammation in a model of secondary allergen challenge

scientific article

Inhibition of spleen tyrosine kinase prevents mast cell activation and airway hyperresponsiveness

scientific article published on 28 September 2005

Inhibition of the development of immediate hypersensitivity by staphylococcal enterotoxin B.

scientific article published on December 1994

Insights into the pathogenesis of asthma utilizing murine models

scientific article published on 17 September 2004

Interleukin (IL)-5 but not immunoglobulin E reconstitutes airway inflammation and airway hyperresponsiveness in IL-4-deficient mice

scientific article published on 01 September 2000

Interleukin 2 activates a receptor-associated protein kinase

scientific article published in September 1987

Interleukin 2 does not induce phosphatidylinositol hydrolysis in activated T cells

scientific article published on 01 April 1986

Interleukin 2 induces a rapid increase in intracellular pH through activation of a Na+/H+ antiport. Cytoplasmic alkalinization is not required for lymphocyte proliferation

scientific article published on 01 October 1985

Interleukin 2-induced lymphocyte proliferation is independent of increases in cytosolic-free calcium concentrations

scientific article published on 01 April 1985

Interleukin-1 receptor antagonist attenuates airway hyperresponsiveness following exposure to ozone

scientific article published on 30 January 2004

Intravenous Immune Globulin in Autoimmune and Inflammatory Diseases ⬇️

scientific article published on November 22, 2012

Intravenous immunoglobulin: properties, mode of action and practical use in dermatology.

scientific article published on January 2007

Introduction to anti-allergic properties of antihistamines

scientific article published in October 2003

Is asthma in childhood different from asthma in adults? Why do we need special approaches to asthma in children?

scientific article published in March 2008

Is forced expiratory volume in one second the best measure of severity in childhood asthma?

scientific article published on 30 January 2004

Is there a link between obesity and asthma?

scientific article

JNK2 regulates the functional plasticity of naturally occurring T regulatory cells and the enhancement of lung allergic responses

scientific article

Jagged1 on dendritic cells and Notch on CD4+ T cells initiate lung allergic responsiveness by inducing IL-4 production

scientific article

Janus kinase 1/3 signaling pathways are key initiators of TH2 differentiation and lung allergic responses

scientific article published on 22 December 2013

Late Onset Hypomorphic RAG2 Deficiency Presentation with Fatal Vaccine-Strain VZV Infection

scientific article

Leukotriene B4 receptor 1 expression on dendritic cells is required for the development of Th2 responses and allergen-induced airway hyperresponsiveness

scientific article

Leukotriene B4 receptor 1 is differentially expressed on peripheral T cells of steroid-sensitive and -resistant asthmatics

scientific article published on 07 January 2014

Leukotriene B4 receptor-1 is essential for allergen-mediated recruitment of CD8+ T cells and airway hyperresponsiveness

scientific article published on 01 April 2005

Leukotriene B4 release from mast cells in IgE-mediated airway hyperresponsiveness and inflammation

scientific article

Lineage specific classification of leukaemia: results of the analysis of sixty cases of childhood leukaemia

scientific article published in October 1985

Local treatment with IL-12 is an effective inhibitor of airway hyperresponsiveness and lung eosinophilia after airway challenge in sensitized mice

scientific article published in July 1998

Loss of T Regulatory Cell Suppression following Signaling through Glucocorticoid-induced Tumor Necrosis Receptor (GITR) Is Dependent on c-Jun N-terminal Kinase Activation ⬇️

scientific article published on March 29, 2012

Low-Dose Lipopolysaccharide Affects Lung Allergic Responses by Regulating Jagged1 Expression on Antigen-Pulsed Dendritic Cells ⬇️

scientific article published on September 6, 2011

MEF2C regulates c‐Jun but not TNF‐α gene expression in stimulated mast cells ⬇️

scientific article published on October 1, 2003

MEK kinase 2 and the adaptor protein Lad regulate extracellular signal-regulated kinase 5 activation by epidermal growth factor via Src

scientific article

MHC class I-dependent Vgamma4+ pulmonary T cells regulate alpha beta T cell-independent airway responsiveness

scientific article

Mast cells, Fc epsilon RI, and IL-13 are required for development of airway hyperresponsiveness after aerosolized allergen exposure in the absence of adjuvant

scientific article published in May 2004

Mechanisms of genotype-phenotype correlation in autosomal dominant anhidrotic ectodermal dysplasia with immune deficiency

scientific article published on 16 June 2017

Microbial Heat Shock Protein 65 Attenuates Airway Hyperresponsiveness and Inflammation by Modulating the Function of Dendritic Cells ⬇️

scientific article published on August 29, 2012

Microfilament assembly is required for anti-IgM dependent MAPK and p90rsk activation in human B lymphocytes.

scientific article published in April 1995

Migration and accumulation of eosinophils toward regional lymph nodes after airway allergen challenge

scientific article published on 01 October 2004

Mismatched antigen prepares gamma delta T cells for suppression of airway hyperresponsiveness

scientific article published on 01 March 2005

Mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2-dependent pathways are essential for CD8+ T cell-mediated airway hyperresponsiveness and inflammation.

scientific article

Mitogen-activated protein kinases as therapeutic targets for asthma

scientific article published on 13 February 2017

Mitogen-induced changes in Ca2+ permeability are not mediated by voltage-gated K+ channels

scientific article

Mitogenic and non-mitogenic ligands trigger a calcium-dependent cytosolic acidification in human T lymphocytes

scientific article published on 01 September 1988

Mitogenic response of human thymocytes: identification of functional Ca2+-dependent and independent signals

scientific article published on 01 October 1986

Modulated expression of genes encoding estrogen metabolizing enzymes by G1-phase cyclin-dependent kinases 6 and 4 in human breast cancer cells

scientific article

Modulation of antigen-induced B and T cell responses by antigen-specific IgE antibodies ⬇️

scientific article published on October 15, 1997

Modulation of p53 activity by IkappaBalpha: evidence suggesting a common phylogeny between NF-kappaB and p53 transcription factors

scientific article

Molecular Endotypes Contribute to the Heterogeneity of Asthma

scientific article published on 21 September 2018

Monoclonal antibodies directed to different epitopes in the CD3-TCR complex induce different states of competence in resting human T cells

scientific article published on 01 March 1992

Monocytes are required to trigger Ca2+ uptake in the proliferative response of human t lymphocytes to staphylococcus aureus protein A ⬇️

scientific article published on November 1, 1984

Monocytes express a non-neurokinin substance P receptor that is functionally coupled to MAP kinase

scientific article published on 01 March 1994

Montelukast during primary infection prevents airway hyperresponsiveness and inflammation after reinfection with respiratory syncytial virus

scientific article

Mouse models of allergic diseases

scientific article published on 14 October 2009

NF-kappaB-dependent induction of cathelicidin-related antimicrobial peptide in murine mast cells by lipopolysaccharide

scientific article

NGF rescues human B lymphocytes from anti-IgM induced apoptosis by activation of PKCzeta

scientific article published in January 2002

Naturally occurring lung CD4(+)CD25(+) T cell regulation of airway allergic responses depends on IL-10 induction of TGF-beta

scientific article published in February 2007

Nebulized IFN-gamma inhibits the development of secondary allergic responses in mice.

scientific article published in August 1996

Nebulized but not parenteral IFN-gamma decreases IgE production and normalizes airways function in a murine model of allergen sensitization

scientific article published on 01 March 1994

Negative regulation of airway responsiveness that is dependent on gammadelta T cells and independent of alphabeta T cells

scientific article published on 01 October 1999

Nerve growth factor induces activation of MAP-kinase and p90rsk in human B lymphocytes

scientific article published on May 1995

Nerve growth factor signal transduction in human B lymphocytes is mediated by gp140trk

scientific article published on 01 September 1996

Nerve growth-factor and anti-CD40 provide opposite signals for the production of IgE in interleukin-4-treated lymphocytes

scientific article

Newborn screening for severe combined immunodeficiency in 11 screening programs in the United States

scientific article published in August 2014

Noninvasive Measurement of Airway Responsiveness in Allergic Mice Using Barometric Plethysmography ⬇️

scientific article published on 01 September 1997

Once-daily ciclesonide in children: efficacy and safety in asthma

scientific article published in March 2006

Outcomes and Treatment Strategies for Autoimmunity and Hyperinflammation in Patients with RAG Deficiency

scientific article published on 12 March 2019

Ozone exposure in vivo and formation of biologically active oxysterols in the lung

scientific article

Ozone increases airway hyperreactivity and mucus hyperproduction in mice previously exposed to allergen

scientific article published on January 2010

Particulate levels are associated with early asthma worsening in children with persistent disease

scientific article published on 16 February 2006

Peanut-induced intestinal allergy is mediated through a mast cell-IgE-FcepsilonRI-IL-13 pathway

scientific article

Pediatric allergic rhinitis: factors affecting treatment choice

scientific article

Pediatric asthma: a different disease

scientific article published on May 2009

Permissive role of calcium in the inhibition of T cell mitogenesis by calmodulin antagonists

scientific article published on 01 November 1983

Physiologic activation of protein kinase C limits IL-2 secretion

scientific article published on 01 March 1989

Physiologic assessment of allergic rhinitis in mice: role of the high-affinity IgE receptor (FcepsilonRI).

scientific article published in November 2005

Pirfenidone modulates airway responsiveness, inflammation, and remodeling after repeated challenge

scientific article

Plasticity of invariant NKT cell regulation of allergic airway disease is dependent on IFN-gamma production

scientific article published on 4 June 2010

Plasticity of regulatory T cells: subversion of suppressive function and conversion to enhancement of lung allergic responses

scientific article published on 01 June 2008

Platelet activating factor activates MAPK and increases in intracellular calcium via independent pathways in B lymphocytes

scientific article published on 01 April 1995

Platelet-activating factor enhances Ig production in B lymphoblastoid cell lines

scientific article published on October 1990

Platelet-activating factor triggers the phosphorylation and activation of MAP-2 kinase and S6 peptide kinase activity in human B cell lines ⬇️

scientific article published on August 15, 1993

Polyclonal activation of human lymphocytes in vitro-II. Reappraisal of T and B cell-specific mitogens

scientific article published in August 1980

Preferential binding of Staphylococcus aureus to skin sites of Th2-mediated inflammation in a murine model

scientific article published on 01 May 2001

Pretreatment with allergen prevents immediate hypersensitivity and airway hyperresponsiveness

scientific article published on 01 January 1996

Primary Immunodeficiency Masquerading as Allergic Disease

scientific article published on 04 September 2015

Prior airway exposure to allergen increases virus-induced airway hyperresponsiveness.

scientific article published in November 2003

Pro: mice are a good model of human airway disease

scientific article published in July 2002

Production of interleukin-4 and interferon-gamma by TCR-V beta-expressing T-cell subsets in allergen-sensitized mice

scientific article published on 01 January 1996

Protein kinase C alpha, betaI, and betaII isozymes regulate cytokine production in mast cells through MEKK2/ERK5-dependent and -independent pathways

scientific article published in November 2005

Purine and pyrimidine metabolism in human T lymphocytes. Regulation of deoxyribonucleotide metabolism

scientific article published on 01 October 1983

Purine metabolism in human T lymphocytes: role of the purine nucleoside cycle

scientific article published on 01 July 1984

Quantitative and qualitative signals determine T-cell cycle entry and progression

scientific article published in October 1999

Quantitative computed tomography detects peripheral airway disease in asthmatic children

scientific article

RANTES (CCL5) regulates airway responsiveness after repeated allergen challenge

scientific article published on 09 March 2006

Rapamycin blocks cell cycle progression of activated T cells prior to events characteristic of the middle to late G1 phase of the cycle

scientific article published on January 1993

Rapamycin potentiates dexamethasone-induced apoptosis and inhibits JNK activity in lymphoblastoid cells

scientific article published on January 1997

Rapamycin-sensitive phosphorylation of ribosomal protein S17 by p70 S6 kinase

scientific article

Rearrangement of the T cell receptor gamma-chain gene in childhood acute lymphoblastic leukemia

scientific article published on 01 December 1987

Rearrangement of the T-cell receptor beta-chain gene in non-T-cell, non-B-cell acute lymphoblastic leukemia of childhood

scientific article published on 01 October 1985

Recommendations for live viral and bacterial vaccines in immunodeficient patients and their close contacts

scientific article

Recurrent rhinovirus infections in a child with inherited MDA5 deficiency.

scientific article

Reduced thymic output, cell cycle abnormalities, and increased apoptosis of T lymphocytes in patients with cartilage-hair hypoplasia

scientific article

Reduction of Antigen-induced Airway Hyperreactivity and Eosinophilia in ICAM-1-deficient Mice ⬇️

scientific article published on June 1, 1998

Regulation of CD23 expression by IL-4 and corticosteroid in human B lymphocytes. Altered response after EBV infection.

scientific article

Regulation of Na+/H+ exchange in lymphocytes

scientific article

Regulation of airway hyperresponsiveness by calcitonin gene-related peptide in allergen sensitized and challenged mice

scientific article published in April 2002

Relationship between rearrangement and transcription of the T-cell receptor alpha, beta, and gamma genes in B-precursor acute lymphoblastic leukemia

scientific article published on 01 February 1989

Requirement for Chemokine Receptor 5 in the Development of Allergen-Induced Airway Hyperresponsiveness and Inflammation ⬇️

scientific article published on July 14, 2011

Requirement for dual signals by anti-CD40 and IL-4 for the induction of nuclear factor-kappa B, IL-6, and IgE in human B lymphocytes ⬇️

scientific article published on August 15, 1998

Requirement for leukotriene B4 receptor 1 in allergen-induced airway hyperresponsiveness

scientific article (publication date: 15 July 2005)

Requirement for the p75 TNF-alpha receptor 2 in the regulation of airway hyperresponsiveness by gamma delta T cells

scientific article published in October 2002

Requirements for the simultaneous presence of phorbol esters and calcium ionophores in the expression of human T lymphocyte proliferation-related genes

scientific article published on 01 September 1987

Respiratory syncytial virus-induced airway hyperresponsiveness is independent of IL-13 compared with that induced by allergen.

scientific article

Response of human B cells to different anti-immunoglobulin isotypes: absence of a correlation between early activation events and cell proliferation

scientific article published in December 1987

Responses of lymphocytes to anisotonic media: volume-regulating behavior ⬇️

scientific article published on March 1, 1984

Responsiveness to respiratory syncytial virus in neonates is mediated through thymic stromal lymphopoietin and OX40 ligand ⬇️

scientific article published on October 1, 2012

Reversal of allergic airway hyperreactivity after long-term allergen challenge depends on gammadelta T cells

scientific article published in December 2003

Role of IgE in the development of allergic airway inflammation and airway hyperresponsiveness--a murine model

scientific article

Role of histamine in the pathophysiology of asthma: immunomodulatory and anti-inflammatory activities of H1-receptor antagonists

scientific article

Role of membrane potential in the regulation of lectin-induced calcium uptake

scientific article published on 01 December 1984

Role of membrane potential in the response of human T lymphocytes to phytohemagglutinin

scientific article published on 01 January 1987

Role of protein kinase C in interleukin 1, anti-T3, and mitogenic lectin-induced interleukin 2 secretion

scientific article published on 01 November 1989

Role of the LTB4/BLT1 pathway in allergen-induced airway hyperresponsiveness and inflammation

scientific article

Role of toll-like receptors in inflammatory bowel disease

scientific article published on 16 November 2017

SLAP deficiency enhances number and function of regulatory T cells preventing chronic autoimmune arthritis in SKG mice

scientific article

Safety and tolerability of increased rate of infusion of intravenous immunoglobulin G, 10% in antibody-deficient patients

scientific article published on 31 May 2006

Selective activation of c-Jun kinase mitogen-activated protein kinase by CD40 on human B cells

scientific article

Separation of lymphoid and myeloid blasts in the mixed blast crisis of chronic myelogenous leukemia: no evidence for Ig gene rearrangement in CALLA-positive blasts

scientific article published in December 1985

Sequential Engagement of FcεRI on Mast Cells and Basophil Histamine H4 Receptor and FcεRI in Allergic Rhinitis ⬇️

scientific article published on December 14, 2012

Serum levels of surfactant protein D are increased in mice with lung tumors

scientific article published in September 2003

Somatic reversion in dedicator of cytokinesis 8 immunodeficiency modulates disease phenotype

scientific article

Specific V beta T cell subsets mediate the immediate hypersensitivity response to ragweed allergen

scientific article published on 01 August 1993

Spectrum of T-lymphocyte activities regulating allergic lung inflammation

scientific article published on July 2017

Spontaneous airway hyperresponsiveness in estrogen receptor-alpha-deficient mice

scientific article published on 9 November 2006

Stem cell factor augments Fc epsilon RI-mediated TNF-alpha production and stimulates MAP kinases via a different pathway in MC/9 mast cells ⬇️

scientific article published on October 1, 1998

Stepwise Epigenetic and Phenotypic Alterations Poise CD8+ T Cells To Mediate Airway Hyperresponsiveness and Inflammation ⬇️

scientific article published on March 18, 2013

Steroidogenic enzyme Cyp11a1 regulates Type 2 CD8+T cell skewing in allergic lung disease ⬇️

scientific article published on April 29, 2013

Strain dependence of airway hyperresponsiveness reflects differences in eosinophil localization in the lung

scientific article published in August 2001

Successful school-based intervention for inner-city children with persistent asthma

scientific article published on June 2004

Successful treatment of eosinophilic esophagitis with ciclesonide ⬇️

scientific article published on 03 April 2012

Surfactant protein D regulates airway function and allergic inflammation through modulation of macrophage function

scientific article published on 25 July 2003

Susceptibility to vaccinia virus infection and spread in mice is determined by age at infection, allergen sensitization and mast cell status

scientific article published on 26 January 2012

Syk activation in dendritic cells is essential for airway hyperresponsiveness and inflammation ⬇️

scientific article published on 09 December 2005

Synergistic antiproliferative effects on HL-60 cells: deferoxamine enhances cytosine arabinoside, methotrexate, and daunorubicin cytotoxicity

scientific article published on 01 January 1988

Systemic and local interferon gamma gene delivery to the lungs for treatment of allergen-induced airway hyperresponsiveness in mice

scientific article published on 01 August 1999

Targeting Pim1 kinase in the treatment of peanut allergy

scientific article

The Atopic Dermatitis Quickscore (ADQ): validation of a new parent-administered atopic dermatitis scoring tool

scientific article published in November 2008

The Critical Role of Complement Alternative Pathway Regulator Factor H in Allergen-Induced Airway Hyperresponsiveness and Inflammation ⬇️

scientific article published on December 14, 2011

The G glycoprotein of respiratory syncytial virus depresses respiratory rates through the CX3C motif and substance P.

scientific article

The Role of RSV Infection in Asthma Initiation and Progression: Findings in a Mouse Model ⬇️

scientific article published on July 2, 2011

The effects of airway microbiome on corticosteroid responsiveness in asthma

scientific article

The enhancement or prevention of airway hyperresponsiveness during reinfection with respiratory syncytial virus is critically dependent on the age at first infection and IL-13 production

scientific article

The expression of deoxyguanosine toxicity in T lymphocytes at different stages of maturation

scientific article published on 01 October 1980

The failure of STAT6-deficient mice to develop airway eosinophilia and airway hyperresponsiveness is overcome by interleukin-5.

scientific article published in October 1999

The failure of interleukin-10-deficient mice to develop airway hyperresponsiveness is overcome by respiratory syncytial virus infection in allergen-sensitized/challenged mice

scientific article published in March 2002

The importance and features of the distal airways in children and adults

scientific article published on December 2009

The intracellular pH of quiescent and proliferating human and rat thymic lymphocytes ⬇️

scientific article published on 01 October 1984

The leukotriene B4 receptor (BLT1) is required for effector CD8+ T cell-mediated, mast cell-dependent airway hyperresponsiveness

scientific article

The origin of T cell colonies from T depleted human lymphocyte populations: analysis by limiting dilution

scientific article published on 01 February 1985

The regulatory role of interleukin 2-responsive T lymphocytes on early and mature erythroid progenitor proliferation

scientific article published on 01 June 1986

The regulatory role of interleukin 2-responsive T lymphocytes on human marrow granulopoiesis

scientific article published on 01 April 1987

The response of children with asthma to ambient particulate is modified by tobacco smoke exposure

scientific article published on 25 August 2011

The role of IL-13 in established allergic airway disease

scientific article published in December 2002

The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines

scientific article published on January 2008

The role of leukotriene B(4) in allergic diseases

scientific article published on December 2008

The role of virus-specific immunoglobulin E in airway hyperresponsiveness

scientific article

The steroidogenic enzyme Cyp11a1 is essential for development of peanut-induced intestinal anaphylaxis

scientific article published on 16 July 2013

Therapeutic interference with interferon-gamma (IFN-gamma) and soluble IL-4 receptor (sIL-4R) in allergic diseases

scientific article

Timing of administration of anti-VLA-4 differentiates airway hyperresponsiveness in the central and peripheral airways in mice

scientific article published on 01 September 2000

Transfer of immediate hypersensitivity and airway hyperresponsiveness by IgE-positive B cells

scientific article published on 01 December 1995

Transfer of the enhancing effect of respiratory syncytial virus infection on subsequent allergic airway sensitization by T lymphocytes.

scientific article published in November 1999

Transient antibody deficiency and abnormal t-suppressor cells induced by phenytoin

scientific article published on 01 February 1982

Transient neutrophil infiltration after allergen challenge is dependent on specific antibodies and Fc gamma III receptors

scientific article published in April 2003

Transmembrane ion fluxes during activation of human T lymphocytes: role of Ca2+, Na+/H+ exchange and phospholipid turnover

scientific article published on February 1987

Triggering through CD40 promotes interleukin-4-induced CD23 production and enhanced soluble CD23 release in atopic disease

scientific article published on 01 September 1996

Tumor Necrosis Factor- α Negatively Regulates Airway Hyperresponsiveness through γδ T Cells ⬇️

scientific article published on December 15, 2001

Tunicamycin inhibits the expression of functional thrombin receptors on human T-lymphoblastoid cells

scientific article published on January 1995

Type 4 phosphodiesterase inhibitors attenuate respiratory syncytial virus-induced airway hyper-responsiveness and lung eosinophilia

scientific article published in August 2000

Understanding asthma using animal models

scientific article

Uptake of extracellular Ca2+ and not recruitment from internal stores is essential for T lymphocyte proliferation

scientific article published on 01 June 1988

Urinary leukotriene E₄ levels identify children with tobacco smoke exposure at risk for asthma exacerbation

scientific article

Urine leukotriene E4 levels are associated with decreased pulmonary function in children with persistent airway obstruction

scientific article published on 27 July 2006

Use of IGIV in the treatment of immune-mediated dermatologic disorders

scientific article published on January 2004

Use of an expanded receptor model for personal exposure analysis in schoolchildren with asthma

article

Use of the health plan employer data and information set for measuring and improving the quality of asthma care

scientific article

V gamma 4+ gamma delta T cells regulate airway hyperreactivity to methacholine in ovalbumin-sensitized and challenged mice

scientific article published in September 2003

Vaccine strain varicella-zoster virus-induced central nervous system vasculopathy as the presenting feature of DOCK8 deficiency

scientific article published on 11 January 2014

Vaccine-induced CD8+ T cell-dependent suppression of airway hyperresponsiveness and inflammation.

scientific article published in July 2009

Vgamma1+ T cells and tumor necrosis factor-alpha in ozone-induced airway hyperresponsiveness

scientific article

Virus-induced airway dysfunction: pathogenesis and biomechanisms

scientific article

Virus-specific IgE enhances airway responsiveness on reinfection with respiratory syncytial virus in newborn mice

scientific article published on 3 December 2008

Volume regulation by human lymphocytes: characterization of the ionic basis for regulatory volume decrease

scientific article published on 01 August 1982

gammadelta T cells as regulators of airway hyperresponsiveness

scientific article

p70 S6 kinase sensitivity to rapamycin is eliminated by amino acid substitution of Thr229.

scientific article published in July 1996

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