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List of works by Michaela Medová

A Comparative Analysis of Individual RAS Mutations in Cancer Biology

scientific article published on 18 October 2019

Biological, diagnostic and therapeutic relevance of the MET receptor signaling in head and neck cancer.

scientific article published on 27 April 2014

Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease

scientific article published on 14 August 2018

Coupling of mutated Met variants to DNA repair via Abl and Rad51.

scientific article

Depletion of FOXM1 via MET Targeting Underlies Establishment of a DNA Damage-Induced Senescence Program in Gastric Cancer.

scientific article

Hepatocyte growth factor secreted by bone marrow stem cell reduce ER stress and improves repair in alveolar epithelial II cells.

scientific article

Hsp90 transcriptionally and post-translationally regulates the expression of NDRG1 and maintains the stability of its modifying kinase GSK3beta.

scientific article

Identification of a MET-eIF4G1 translational regulation axis that controls HIF-1α levels under hypoxia.

scientific article published on 2 May 2018

Impact of MET targeting on tumor-associated angiogenesis and growth of MET mutations-driven models of liver cancer

scientific article

Impact of p53 Status on Radiosensitization of Tumor Cells by MET Inhibition-Associated Checkpoint Abrogation

scientific article published on 10 September 2015

Interplay between receptor tyrosine kinases and hypoxia signaling in cancer.

scientific article

KRAS and HRAS mutations confer resistance to MET targeting in preclinical models of MET-expressing tumor cells.

scientific article published on 14 April 2015

MET Inhibition Results in DNA Breaks and Synergistically Sensitizes Tumor Cells to DNA-Damaging Agents Potentially by Breaching a Damage-Induced Checkpoint Arrest

scientific article published on October 1, 2010

MET inhibition in tumor cells by PHA665752 impairs homologous recombination repair of DNA double strand breaks

scientific article published on May 9, 2011

MET targeting: time for a rematch

scientific article published on 07 February 2020

Metabolomics reveals tepotinib-related mitochondrial dysfunction in MET-activating mutations-driven models

scientific article published on 11 May 2019

OMIP-045: Characterizing human head and neck tumors and cancer cell lines with mass cytometry

scientific article published on 12 April 2018

Oncogene addiction as a foundation of targeted cancer therapy: The paradigm of the MET receptor tyrosine kinase

scientific article published on 11 December 2018

PIK3CA hotspot mutations differentially impact responses to MET targeting in MET-driven and non-driven preclinical cancer models

scientific article

Profiling invasiveness in head and neck cancer: recent contributions of genomic and transcriptomic approaches

scientific article

ProtRank: bypassing the imputation of missing values in differential expression analysis of proteomic data

scientific article published on 09 November 2019

Protective autophagy is involved in resistance towards MET inhibitors in human gastric adenocarcinoma cells.

scientific article published on 9 January 2013

Senescence as biologic endpoint following pharmacological targeting of receptor tyrosine kinases in cancer.

scientific article

Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury

scientific article published on 06 April 2021

Targeting of the MET receptor tyrosine kinase by small molecule inhibitors leads to MET accumulation by impairing the receptor downregulation

scientific journal article

Targeting the MET Receptor Tyrosine Kinase as a Strategy for Radiosensitization in Locoregionally Advanced Head and Neck Squamous Cell Carcinoma

scientific article published on 19 November 2019

The LIM Protein Ajuba Augments Tumor Metastasis in Colon Cancer

scientific article published on 15 July 2020

The Molecular Crosstalk between the MET Receptor Tyrosine Kinase and the DNA Damage Response-Biological and Clinical Aspects

scientific article

The novel ATP-competitive inhibitor of the MET hepatocyte growth factor receptor EMD1214063 displays inhibitory activity against selected MET-mutated variants.

scientific article published on 23 September 2013

The relevance of tyrosine kinase inhibitors for global metabolic pathways in cancer

scientific article

Verteporfin-induced lysosomal compartment dysregulation potentiates the effect of sorafenib in hepatocellular carcinoma

scientific article published on 03 October 2019