List of works - Dominique Michaud

2-DE proteome maps for the leaf apoplast of Nicotiana benthamiana

scientific article published on 01 July 2010

A Chimeric Affinity Tag for Efficient Expression and Chromatographic Purification of Heterologous Proteins from Plants.

scientific article published on 15 February 2016

A SELDI-TOF MS procedure for the detection, quantitation, and preliminary characterization of low-molecular-weight recombinant proteins expressed in transgenic plants

scientific article

A companion protease inhibitor for the protection of cytosol-targeted recombinant proteins in plants

scientific article published on 28 December 2009

A hybrid, broad-spectrum inhibitor of Colorado potato beetle aspartate and cysteine digestive proteinases

scientific article published in September 2005

A multicomponent, elicitor-inducible cystatin complex in tomato, Solanum lycopersicum

scientific article

A protease activity-depleted environment for heterologous proteins migrating towards the leaf cell apoplast

scientific article published on 05 September 2011

A proteomic analysis of the aphid Macrosiphum euphorbiae under heat and radiation stress.

scientific article published in November 2008

Activity-based proteomics reveals nine target proteases for the recombinant protein-stabilizing inhibitor SlCYS8 in Nicotiana benthamiana

scientific article published on 14 March 2019

An Accessory Protease Inhibitor to Increase the Yield and Quality of a Tumour-Targeting mAb in Nicotiana benthamiana Leaves

scientific article

An in-built proteinase inhibitor system for the protection of recombinant proteins recovered from transgenic plants

scientific article published on 01 May 2006

Aphid clonal resistance to a parasitoid fails under heat stress.

scientific article published on 22 November 2005

Beneficial 'unintended effects' of a cereal cystatin in transgenic lines of potato, Solanum tuberosum

scientific article

Cereal cystatins delay sprouting and nutrient loss in tubers of potato, Solanum tuberosum

scientific article published on 21 December 2015

Colorado potato beetles compensate for tomato cathepsin D inhibitor expressed in transgenic potato

scientific article published in March 2004

Colorado potato beetles show differential digestive compensatory responses to host plants expressing distinct sets of defense proteins

scientific article published in March 2004

Companion Protease Inhibitors for the In Situ Protection of Recombinant Proteins in Plants.

scientific article published in January 2016

Companion protease inhibitors to protect recombinant proteins in transgenic plant extracts

scientific article published on 01 January 2009

Cystatin Activity-Based Protease Profiling to Select Protease Inhibitors Useful in Plant Protection

scientific article published on 01 January 2020

Deleterious effects of plant cystatins against the banana weevil Cosmopolites sordidus.

scientific article published on February 2010

Discrimination of differentially inhibited cysteine proteases by activity-based profiling using cystatin variants with tailored specificities

scientific article published on 6 November 2012

Early presence of an enolase in the oviposition injecta of the aphid parasitoid Aphidius ervi analyzed with chitosan beads as artificial hosts.

scientific article published on 28 November 2012

Functional proteomics-aided selection of protease inhibitors for herbivore insect control

scientific article published on 13 December 2016

Harnessing the functional diversity of plant cystatins to design inhibitor variants highly active against herbivorous arthropod digestive proteases

scientific article published in 2021

Hybrid protease inhibitors for pest and pathogen control--a functional cost for the fusion partners?

scientific article published on 22 April 2008

Impact of environmental stress on aphid clonal resistance to parasitoids: Role of Hamiltonella defensa bacterial symbiosis in association with a new facultative symbiont of the pea aphid

scientific article published in July 2009

Leaf proteome rebalancing in Nicotiana benthamiana for upstream enrichment of a transiently expressed recombinant protein.

scientific article published on 19 August 2015

Modulating secretory pathway pH by proton channel co-expression can increase recombinant protein stability in plants

scientific article published on 24 April 2015

Modulating the proteinase inhibitory profile of a plant cystatin by single mutations at positively selected amino acid sites.

scientific article published on 12 September 2006

Molecular interactions between an insect predator and its herbivore prey on transgenic potato expressing a cysteine proteinase inhibitor from rice

scientific article published in September 2003

MsCYS1, a developmentally-regulated cystatin from alfalfa

scientific article

Multimodal protein constructs for herbivore insect control

scientific article published on 12 June 2012

On-chip detection of low-molecular-weight recombinant proteins in plant crude extracts by SELDI-TOF MS.

scientific article

Oryzacystatin I expressed in transgenic potato induces digestive compensation in an insect natural predator via its herbivorous prey feeding on the plant

scientific article published in September 2003

Plant cystatins

scientific article published on 14 June 2010

Population-associated heterogeneity of the digestive Cys protease complement in Colorado potato beetle, Leptinotarsa decemlineata

scientific article

Positive selection of digestive Cys proteases in herbivorous Coleoptera

scientific article published on 8 August 2015

Production of Biopharmaceuticals in Nicotiana benthamiana-Axillary Stem Growth as a Key Determinant of Total Protein Yield.

scientific article published on 11 June 2019

Production of oryzacystatins I and II in Escherichia coli using the glutathione S-transferase gene fusion system

scientific article published in 1994

Protection of recombinant mammalian antibodies from development-dependent proteolysis in leaves of Nicotiana benthamiana.

scientific article

Protein phosphorylation and membrane association of sucrose synthase in developing tomato fruit

scientific article published on 01 May 2006

Proteomes of the aphid Macrosiphum euphorbiae in its resistance and susceptibility responses to differently compatible parasitoids

scientific article published on 10 May 2008

Proteomic profiling of a parasitic wasp exposed to constant and fluctuating cold exposure.

scientific article published on 14 July 2007

Proteomic profiling of aphid Macrosiphum euphorbiae responses to host-plant-mediated stress induced by defoliation and water deficit

scientific article published on 12 March 2007

Recombinant cystatins in plants

scientific article published on 11 June 2019

Recombinant protease inhibitors for herbivore pest control: a multitrophic perspective

scientific article published on 25 June 2010

Recombinant protein susceptibility to proteolysis in the plant cell secretory pathway is pH-dependent.

scientific article published on 4 April 2018

Single substitutions to closely related amino acids contribute to the functional diversification of an insect-inducible, positively selected plant cystatin.

scientific article published on February 2016

Tailoring the specificity of a plant cystatin toward herbivorous insect digestive cysteine proteases by single mutations at positively selected amino acid sites

scientific article

Tomato cystatin SlCYS8 as a stabilizing fusion partner for human serpin expression in plants

scientific article published on 5 August 2013

Tubers from potato lines expressing a tomato Kunitz protease inhibitor are substantially equivalent to parental and transgenic controls.

scientific article published on 28 December 2009

Unintended molecular interactions in transgenic plants expressing clinically useful proteins: the case of bovine aprotinin traveling the potato leaf cell secretory pathway.

scientific article published in February 2009

Wounding, insect chewing and phloem sap feeding differentially alter the leaf proteome of potato, Solanum tuberosum L.

scientific article published on 26 December 2012

pH Gradient Mitigation in the Leaf Cell Secretory Pathway Attenuates the Defense Response of Nicotiana benthamiana to Agroinfiltration

scientific article published on 12 December 2019

List of works by Dominique Michaud

2-DE proteome maps for the leaf apoplast of Nicotiana benthamiana

A Chimeric Affinity Tag for Efficient Expression and Chromatographic Purification of Heterologous Proteins from Plants.

A SELDI-TOF MS procedure for the detection, quantitation, and preliminary characterization of low-molecular-weight recombinant proteins expressed in transgenic plants

A companion protease inhibitor for the protection of cytosol-targeted recombinant proteins in plants

A hybrid, broad-spectrum inhibitor of Colorado potato beetle aspartate and cysteine digestive proteinases

A multicomponent, elicitor-inducible cystatin complex in tomato, Solanum lycopersicum

A protease activity-depleted environment for heterologous proteins migrating towards the leaf cell apoplast

A proteomic analysis of the aphid Macrosiphum euphorbiae under heat and radiation stress.

Activity-based proteomics reveals nine target proteases for the recombinant protein-stabilizing inhibitor SlCYS8 in Nicotiana benthamiana

An Accessory Protease Inhibitor to Increase the Yield and Quality of a Tumour-Targeting mAb in Nicotiana benthamiana Leaves

An in-built proteinase inhibitor system for the protection of recombinant proteins recovered from transgenic plants

Aphid clonal resistance to a parasitoid fails under heat stress.

Beneficial 'unintended effects' of a cereal cystatin in transgenic lines of potato, Solanum tuberosum

Cereal cystatins delay sprouting and nutrient loss in tubers of potato, Solanum tuberosum

Colorado potato beetles compensate for tomato cathepsin D inhibitor expressed in transgenic potato

Colorado potato beetles show differential digestive compensatory responses to host plants expressing distinct sets of defense proteins

Companion Protease Inhibitors for the In Situ Protection of Recombinant Proteins in Plants.

Companion protease inhibitors to protect recombinant proteins in transgenic plant extracts

Cystatin Activity-Based Protease Profiling to Select Protease Inhibitors Useful in Plant Protection

Deleterious effects of plant cystatins against the banana weevil Cosmopolites sordidus.

Discrimination of differentially inhibited cysteine proteases by activity-based profiling using cystatin variants with tailored specificities

Early presence of an enolase in the oviposition injecta of the aphid parasitoid Aphidius ervi analyzed with chitosan beads as artificial hosts.

Functional proteomics-aided selection of protease inhibitors for herbivore insect control

Harnessing the functional diversity of plant cystatins to design inhibitor variants highly active against herbivorous arthropod digestive proteases

Hybrid protease inhibitors for pest and pathogen control--a functional cost for the fusion partners?

Impact of environmental stress on aphid clonal resistance to parasitoids: Role of Hamiltonella defensa bacterial symbiosis in association with a new facultative symbiont of the pea aphid

Leaf proteome rebalancing in Nicotiana benthamiana for upstream enrichment of a transiently expressed recombinant protein.

Modulating secretory pathway pH by proton channel co-expression can increase recombinant protein stability in plants

Modulating the proteinase inhibitory profile of a plant cystatin by single mutations at positively selected amino acid sites.

Molecular interactions between an insect predator and its herbivore prey on transgenic potato expressing a cysteine proteinase inhibitor from rice

MsCYS1, a developmentally-regulated cystatin from alfalfa

Multimodal protein constructs for herbivore insect control

On-chip detection of low-molecular-weight recombinant proteins in plant crude extracts by SELDI-TOF MS.

Oryzacystatin I expressed in transgenic potato induces digestive compensation in an insect natural predator via its herbivorous prey feeding on the plant

Plant cystatins

Population-associated heterogeneity of the digestive Cys protease complement in Colorado potato beetle, Leptinotarsa decemlineata

Positive selection of digestive Cys proteases in herbivorous Coleoptera

Production of Biopharmaceuticals in Nicotiana benthamiana-Axillary Stem Growth as a Key Determinant of Total Protein Yield.

Production of oryzacystatins I and II in Escherichia coli using the glutathione S-transferase gene fusion system

Protection of recombinant mammalian antibodies from development-dependent proteolysis in leaves of Nicotiana benthamiana.

Protein phosphorylation and membrane association of sucrose synthase in developing tomato fruit

Proteomes of the aphid Macrosiphum euphorbiae in its resistance and susceptibility responses to differently compatible parasitoids

Proteomic profiling of a parasitic wasp exposed to constant and fluctuating cold exposure.

Proteomic profiling of aphid Macrosiphum euphorbiae responses to host-plant-mediated stress induced by defoliation and water deficit

Recombinant cystatins in plants

Recombinant protease inhibitors for herbivore pest control: a multitrophic perspective

Recombinant protein susceptibility to proteolysis in the plant cell secretory pathway is pH-dependent.

Single substitutions to closely related amino acids contribute to the functional diversification of an insect-inducible, positively selected plant cystatin.

Tailoring the specificity of a plant cystatin toward herbivorous insect digestive cysteine proteases by single mutations at positively selected amino acid sites

Tomato cystatin SlCYS8 as a stabilizing fusion partner for human serpin expression in plants

Tubers from potato lines expressing a tomato Kunitz protease inhibitor are substantially equivalent to parental and transgenic controls.

Unintended molecular interactions in transgenic plants expressing clinically useful proteins: the case of bovine aprotinin traveling the potato leaf cell secretory pathway.

Wounding, insect chewing and phloem sap feeding differentially alter the leaf proteome of potato, Solanum tuberosum L.

pH Gradient Mitigation in the Leaf Cell Secretory Pathway Attenuates the Defense Response of Nicotiana benthamiana to Agroinfiltration