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List of works by Emmanuel Darcq

A novel anxiogenic role for the delta opioid receptor expressed in GABAergic forebrain neurons.

scientific article

BOLD Imaging in Awake Wild-Type and Mu-Opioid Receptor Knock-Out Mice Reveals On-Target Activation Maps in Response to Oxycodone.

scientific article

Biased Signaling of the Mu Opioid Receptor Revealed in Native Neurons

article

Chromatin remodeling — a novel strategy to control excessive alcohol drinking ⬇️

scientific article published on February 19, 2013

Control of aversion by glycine-gated GluN1/GluN3A NMDA receptors in the adult medial habenula

scientific article published on 01 October 2019

Current strategies toward safer mu opioid receptor drugs for pain management

scientific article published on 15 March 2019

Deformation-based Morphometry MRI Reveals Brain Structural Modifications in Living Mu Opioid Receptor Knockout Mice

scientific article published on 03 December 2018

Deletion of the mu opioid receptor gene in mice reshapes the reward-aversion connectome

scientific article

Design, Synthesis, and Structure-Activity Relationship Studies of (4-Alkoxyphenyl)glycinamides and Bioisosteric 1,3,4-Oxadiazoles as GPR88 Agonists

scientific article published on 18 November 2020

Discovery of a Potent, Selective, and Brain-Penetrant Small Molecule that Activates the Orphan Receptor GPR88 and Reduces Alcohol Intake

scientific article published on 30 July 2018

Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior.

scientific article

Expression map of 78 brain-expressed mouse orphan GPCRs provides a translational resource for neuropsychiatric research

scientific article published on 06 August 2018

Fyn Signaling Is Compartmentalized to Dopamine D1 Receptor Expressing Neurons in the Dorsal Medial Striatum.

scientific article published on 31 August 2017

GPCR and Alcohol-Related Behaviors in Genetically Modified Mice

scientific article published on 01 January 2020

GPR88 in D1R-Type and D2R-Type Medium Spiny Neurons Differentially Regulates Affective and Motor Behavior

scientific article published on 01 July 2019

Impaired emotional-like behavior and serotonergic function during protracted abstinence from chronic morphine

scientific article

Increased Alcohol Seeking in Mice Lacking Gpr88 Involves Dysfunctional Mesocorticolimbic Networks.

scientific article published on 9 February 2018

Inhibition of striatal-enriched tyrosine phosphatase 61 in the dorsomedial striatum is sufficient to increased ethanol consumption

scientific article

Lack of anticipatory behavior in Gpr88 knockout mice showed by automatized home cage phenotyping.

scientific article published on 25 March 2018

Mapping GPR88-Venus illuminates a novel role for GPR88 in sensory processing.

scientific article published on 6 November 2017

MicroRNA-30a-5p in the prefrontal cortex controls the transition from moderate to excessive alcohol consumption

scientific article published on 11 November 2014

MicroRNA-30a-5p in the prefrontal cortex controls the transition from moderate to excessive alcohol consumption.

scientific article published on 21 October 2014

Mu Opioid Receptors in Gamma-Aminobutyric Acidergic Forebrain Neurons Moderate Motivation for Heroin and Palatable Food.

scientific article published on 26 December 2016

Mu opioid receptors in the medial habenula contribute to naloxone aversion

scientific article published on 20 April 2019

Mu-opioid receptor activation induces transcriptional plasticity in the central extended amygdala.

scientific article published on June 2008

Opioid receptors: drivers to addiction?

scientific article published on 01 August 2018

PI3K signaling in the locus coeruleus: a new molecular pathway for ADHD research

scientific article

Protein tyrosine phosphatase α in the dorsomedial striatum promotes excessive ethanol-drinking behaviors

scientific article published on September 2013

Protracted abstinence from distinct drugs of abuse shows regulation of a common gene network.

scientific article published on 28 September 2011

RSK2 signaling in brain habenula contributes to place aversion learning ⬇️

scientific article published on August 18, 2011

RSK2 signaling in medial habenula contributes to acute morphine analgesia.

scientific article published on 4 January 2012

Rare susceptibility variants for bipolar disorder suggest a role for G protein-coupled receptors.

scientific article published on 21 November 2017

Recommending buprenorphine for pain management

scientific article published on 03 December 2018

Striatal-enriched protein tyrosine phosphatase controls responses to aversive stimuli: implication for ethanol drinking.

scientific article

Targeting morphine-responsive neurons: generation of a knock-in mouse line expressing Cre recombinase from the mu opioid receptor gene locus

scientific article published on 07 May 2020

The BDNF Valine 68 to Methionine Polymorphism Increases Compulsive Alcohol Drinking in Mice That Is Reversed by Tropomyosin Receptor Kinase B Activation.

scientific article published on 12 June 2015

The Control of Reward Seeking

scientific article published on 01 June 2018

The Negative Affect of Protracted Opioid Abstinence: Progress and Perspectives From Rodent Models

scientific article published on 06 August 2019

The Neurotrophic Factor Receptor p75 in the Rat Dorsolateral Striatum Drives Excessive Alcohol Drinking

scientific article published on 28 September 2016

TouchScreen-based phenotyping: altered stimulus/reward association and lower perseveration to gain a reward in mu opioid receptor knockout mice

scientific article published on 11 March 2019

Translating the Habenula-From Rodents to Humans.

scientific article published on 7 June 2016

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