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Authors whose works are in public domain in at least one jurisdiction

List of works by Sophie A Valkenburg

1-50 of 54 results

Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion

scientific article

Cross-reactive CD8 + T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses

scientific article

Human mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo.

scientific article published on 14 March 2016

Stalking influenza by vaccination with pre-fusion headless HA mini-stem

scientific article

Systematic identification of immunodominant CD8+ T-cell responses to influenza A virus in HLA-A2 individuals

scientific article

Immunity to seasonal and pandemic influenza A viruses

scientific article

Protective Efficacy of Cross-Reactive CD8+ T Cells Recognising Mutant Viral Epitopes Depends on Peptide-MHC-I Structural Interactions and T Cell Activation Threshold

scientific article

Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses

scientific article published on 31 March 2016

Universal immunity to influenza must outwit immune evasion

scientific article

Early priming minimizes the age-related immune compromise of CD8⁺ T cell diversity and function

scientific article (publication date: February 2012)

Acute emergence and reversion of influenza A virus quasispecies within CD8+ T cell antigenic peptides

scientific article

IL-15 adjuvanted multivalent vaccinia-based universal influenza vaccine requires CD4+ T cells for heterosubtypic protection

scientific article

ORF8 and ORF3b antibodies are accurate serological markers of early and late SARS-CoV-2 infection

scientific article published on 17 August 2020

Use it or lose it: establishment and persistence of T cell memory

scientific article

Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine

scientific article published on 26 March 2018

Highly pathogenic avian influenza A H5N1 and pandemic H1N1 virus infections have different phenotypes in Toll-like receptor 3 knockout mice.

scientific article

Generation of Live Attenuated Influenza Virus by Using Codon Usage Bias.

scientific article

Memory precursor phenotype of CD8+ T cells reflects early antigenic experience rather than memory numbers in a model of localized acute influenza infection.

scientific article published on 25 January 2011

Preemptive priming readily overcomes structure-based mechanisms of virus escape

scientific article

Fixing an irrelevant TCR alpha chain reveals the importance of TCR beta diversity for optimal TCR alpha beta pairing and function of virus-specific CD8+ T cells.

scientific article published in September 2010

CLEC5A-Mediated Enhancement of the Inflammatory Response in Myeloid Cells Contributes to Influenza Virus Pathogenicity In Vivo

scientific article

Homogenization of TCR repertoires within secondary CD62Lhigh and CD62Llow virus-specific CD8+ T cell populations

scientific article published in June 2008

Induction of protective CD4+ T cell-mediated immunity by a Leishmania peptide delivered in recombinant influenza viruses

scientific article published on 21 March 2012

Molecular Imprint of Exposure to Naturally Occurring Genetic Variants of Human Cytomegalovirus on the T cell Repertoire

scientific article published on 10 February 2014

Polyfunctional CD8(+) T cells are associated with the vaccination-induced control of a novel recombinant influenza virus expressing an HCV epitope.

scientific article published on 4 April 2012

Perturbed CD8(+) T cell immunity across universal influenza epitopes in the elderly

scientific article published on 19 September 2017

Protection by universal influenza vaccine is mediated by memory CD4 T cells

scientific article published on 07 June 2018

Lack of heterologous cross-reactivity towards HLA-A*02:01 restricted viral epitopes is underpinned by distinct αβT cell receptor signatures

scientific article

Multiplexed combinatorial tetramer staining in a mouse model of virus infection.

scientific article published on 15 June 2010

Comparative Immunogenicity of Several Enhanced Influenza Vaccine Options for Older Adults: A Randomized, Controlled Trial

scientific article published on 12 December 2019

The Hurdles From Bench to Bedside in the Realization and Implementation of a Universal Influenza Vaccine

scientific article published on 02 July 2018

Immune responses to twice-annual influenza vaccination in older adults in Hong Kong.

scientific article

Preexisting Antibody-Dependent Cellular Cytotoxicity-Activating Antibody Responses Are Stable Longitudinally and Cross-reactive Responses Are Not Boosted by Recent Influenza Exposure.

scientific article

Beyond the Spike: identification of viral targets of the antibody response to SARS-CoV-2 in COVID-19 patients

scientific article published on 03 May 2020

Diversity and clonotypic composition of influenza-specific CD8+ TCR repertoires remain unaltered in the absence of Aire

scientific article published in March 2010

OTUB1 Is a Key Regulator of RIG-I-Dependent Immune Signaling and Is Targeted for Proteasomal Degradation by Influenza A NS1

scientific article published on 01 February 2020

Characterization of SARS-CoV-2 nucleocapsid protein reveals multiple functional consequences of the C-terminal domain

scientific article

Characterization of SARS-CoV-2 N protein reveals multiple functional consequences of the C-terminal domain

scientific article published on 30 November 2020

Cross-reactive antibody-dependent cellular cytotoxicity antibodies are increased by recent infection in a household study of influenza transmission

scientific article published on 20 November 2019

Correction: Early Priming Minimizes the Age-Related Immune Compromise of CD8+ T Cell Diversity and Function.

scientific article published on 15 March 2012

Combined use of live-attenuated and inactivated influenza vaccines to enhance heterosubtypic protection

scientific article published on 21 September 2018

Author Correction: ORF8 and ORF3b antibodies are accurate serological markers of early and late SARS-CoV-2 infection

scientific article published on 27 August 2020

Serologic Responses in Healthy Adult with SARS-CoV-2 Reinfection, Hong Kong, August 2020

scientific article published on 22 October 2020

Development and Assessment of a Pooled Serum as Candidate Standard to Measure Influenza A Virus Group 1 Hemagglutinin Stalk-Reactive Antibodies

scientific article published on 09 November 2020

Vaccination with ADCC activating HA peptide epitopes provides 1 partial protection from influenza infection

scientific article published on 24 July 2020

Author Correction: Immunogenicity and reactogenicity of SARS-CoV-2 vaccines BNT162b2 and CoronaVac in healthy adolescents

scientific article published on 15 August 2022

Immunogenicity and reactogenicity of SARS-CoV-2 vaccines BNT162b2 and CoronaVac in healthy adolescents

scientific article published on 28 June 2022

Assessment of enhanced influenza vaccination finds that FluAd conveys an advantage in mice and older adults

scientific article published on 03 February 2020

Turning influenza vaccinology on its head to reveal the stalk

scientific article published on 17 October 2019

Superior antibody and membrane protein-specific T cell responses to CoronaVac by intradermal versus intramuscular routes in adolescents