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List of works by Rosalia Crupi

2-Pentadecyl-2-Oxazoline Reduces Neuroinflammatory Environment in the MPTP Model of Parkinson Disease

scientific article published on 14 April 2018

2-pentadecyl-2-oxazoline: Identification in coffee, synthesis and activity in a rat model of carrageenan-induced hindpaw inflammation

scientific article published on 12 April 2016

A novel composite formulation of palmitoylethanolamide and quercetin decreases inflammation and relieves pain in inflammatory and osteoarthritic pain models

scientific article

A novel protective formulation of Palmitoylethanolamide in experimental model of contrast agent induced nephropathy.

scientific article published on 13 October 2015

Absence of TLR4 reduces neurovascular unit and secondary inflammatory process after traumatic brain injury in mice

scientific article

Absence of formyl peptide receptor 1 causes endometriotic lesion regression in a mouse model of surgically-induced endometriosis

scientific article published on 31 July 2018

Adelmidrol + sodium hyaluronate in IC/BPS or conditions associated to chronic urothelial inflammation. A translational study

scientific article published on 22 May 2018

Adelmidrol, a Palmitoylethanolamide Analogue, as a New Pharmacological Treatment for the Management of Inflammatory Bowel Disease

scientific article published on 13 September 2016

Adelmidrol: A New Promising Antioxidant and Anti-Inflammatory Therapeutic Tool in Pulmonary Fibrosis

scientific article published on 09 July 2020

Administration of palmitoylethanolamide (PEA) protects the neurovascular unit and reduces secondary injury after traumatic brain injury in mice.

scientific article published on 3 August 2012

Aging and Parkinson's Disease: Inflammaging, neuroinflammation and biological remodeling as key factors in pathogenesis

scientific article published on 25 October 2017

An Update of Palmitoylethanolamide and Luteolin Effects in Preclinical and Clinical Studies of Neuroinflammatory Events

scientific article published on 05 March 2020

Anti-Inflammatory and Neuroprotective Effects of Co-UltraPEALut in a Mouse Model of Vascular Dementia.

scientific article published on 6 June 2017

Beneficial Effects of Co-Ultramicronized Palmitoylethanolamide/Luteolin in a Mouse Model of Autism and in a Case Report of Autism.

scientific article

Biochemical Evaluation of the Antioxidant Effects of Hydroxytyrosol on Pancreatitis-Associated Gut Injury

scientific article published on 22 August 2020

Biomarkers of Exposure to Chemical Contamination in the Commercial Fish Species Lepidopus caudatus (Euphrasen, 1788): A Particular Focus on Plastic Additives

scientific article published on 16 July 2019

Canine atopic dermatitis: Role of luteolin as new natural treatment

scientific article published on 02 August 2020

Cashew (Anacardium occidentale L.) Nuts Counteract Oxidative Stress and Inflammation in an Acute Experimental Model of Carrageenan-Induced Paw Edema

scientific article published on 24 July 2020

Cashew (Anacardium occidentale L.) Nuts Modulate the Nrf2 and NLRP3 Pathways in Pancreas and Lung after Induction of Acute Pancreatitis by Cerulein

scientific article published on 14 October 2020

Cellular stress response, sirtuins and UCP proteins in Alzheimer disease: role of vitagenes

scientific article published on 17 October 2013

Clinical and Immunological Response in Dogs Naturally Infected by L. infantum Treated with a Nutritional Supplement

scientific article published on 30 July 2019

Clinical efficacy of bronchodilators in equine asthma: Looking for minimal important difference

scientific article published on 01 July 2019

Co-Ultramicronized Palmitoylethanolamide/Luteolin Promotes Neuronal Regeneration after Spinal Cord Injury

scientific article published on 8 March 2016

Co-micronized Palmitoylethanolamide/Polydatin Treatment Causes Endometriotic Lesion Regression in a Rodent Model of Surgically Induced Endometriosis.

scientific article published on 14 October 2016

Co-ultraPEALut: Role in Preclinical and Clinical Delirium Manifestations

scientific article published on 17 June 2019

Combination therapy with melatonin and dexamethasone in a mouse model of traumatic brain injury.

scientific article

Combined Effects of Potassium Perchlorate and a Neonicotinoid on Zebrafish Larvae (Danio rerio)

scientific article published in 2022

Crude Venom from Nematocysts of the Jellyfish Pelagia noctiluca as a Tool to Study Cell Physiology.

scientific article

Cytoprotective and Antioxidant Effects of Hydrolysates from Black Soldier Fly (Hermetia illucens)

scientific article published in 2023

Cytotoxicity of the nematocyst venom from the sea anemone Aiptasia mutabilis

scientific article published on 01 December 2004

Detection of artificial cellulose microfibers in Boops boops from the northern coasts of Sicily (Central Mediterranean)

scientific article published on 12 July 2019

Dietary Supplementation with Palmitoyl-Glucosamine Co-Micronized with Curcumin Relieves Osteoarthritis Pain and Benefits Joint Mobility

scientific article published on 08 October 2020

Effect of Artesunate on Leishmania Amazonesis Induced Neuroinflammation and Nociceptive Behavior in Male Balb/C Mice

scientific article published on 27 March 2020

Effect of N-palmitoylethanolamine-oxazoline on comorbid neuropsychiatric disturbance associated with inflammatory bowel disease

scientific article published on 16 January 2020

Effect of PEA-OXA on neuropathic pain and functional recovery after sciatic nerve crush

scientific article published on 14 September 2018

Effect of Tempol, a Membrane-Permeable Free Radical Scavenger, on In Vitro Model of Eye Inflammation on Rabbit Corneal Cells

scientific article published on 01 December 2019

Effects of Hydroxytyrosol against Lipopolysaccharide-Induced Inflammation and Oxidative Stress in Bovine Mammary Epithelial Cells: A Natural Therapeutic Tool for Bovine Mastitis

scientific article published on 03 August 2020

Effects of a new compound containing Palmitoylethanolamide and Baicalein in myocardial ischaemia/reperfusion injury in vivo

scientific article published on 19 September 2018

Effects of a polyphenol present in olive oil, oleuropein aglycone, in a murine model of intestinal ischemia/reperfusion injury

scientific article published on 11 December 2012

Effects of palmitoylethanolamide and luteolin in an animal model of anxiety/depression.

scientific article published in November 2013

Effects of palmitoylethanolamide and silymarin combination treatment in an animal model of kidney ischemia and reperfusion

scientific article published on 14 May 2015

Erratum to: Micronized/ultramicronized palmitoylethanolamide displays superior oral efficacy compared to nonmicronized palmitoylethanolamide in a rat model of inflammatory pain.

scientific article

Exogenous T3 administration provides neuroprotection in a murine model of traumatic brain injury

scientific article published on 8 January 2013

Formyl Peptide Receptor 1 Signaling in Acute Inflammation and Neural Differentiation Induced by Traumatic Brain Injury

scientific article published on 20 August 2020

Hormesis, cellular stress response and neuroinflammation in schizophrenia: Early onset versus late onset state

scientific article published on 29 November 2016

Hypericum perforatum treatment: effect on behaviour and neurogenesis in a chronic stress model in mice

scientific article

Inflammasomes, hormesis, and antioxidants in neuroinflammation: Role of NRLP3 in Alzheimer disease.

scientific article published on 8 November 2016

Intestinal immunity of dogfish Scyliorhinus canicula spiral valve: A histochemical, immunohistochemical and confocal study

scientific article published on 31 January 2019

Management of Traumatic Brain Injury: From Present to Future

scientific article published on 02 April 2020

Melatonin Plus Folic Acid Treatment Ameliorates Reserpine-Induced Fibromyalgia: An Evaluation of Pain, Oxidative Stress, and Inflammation

scientific article published on 06 December 2019

Melatonin treatment mimics the antidepressant action in chronic corticosterone-treated mice

scientific article published in June 2010

Melatonin's stimulatory effect on adult hippocampal neurogenesis in mice persists after ovariectomy

scientific article published on 06 June 2011

Metabolic drug interactions between antidepressants and anticancer drugs: focus on selective serotonin reuptake inhibitors and hypericum extract.

scientific article

Micronized palmitoylethanolamide reduces joint pain and glial cell activation

scientific article published on 18 August 2018

Micronized/ultramicronized palmitoylethanolamide displays superior oral efficacy compared to nonmicronized palmitoylethanolamide in a rat model of inflammatory pain.

scientific article published on 28 August 2014

Microplastics occurrence in the Tyrrhenian waters and in the gastrointestinal tract of two congener species of seabreams

scientific article published on 25 January 2019

Middle Cerebral Artery Occlusion by an Intraluminal Suture Method

scientific article published in January 2018

Modulation of NLRP3 Inflammasome through Formyl Peptide Receptor 1 (Fpr-1) Pathway as a New Therapeutic Target in Bronchiolitis Obliterans Syndrome

scientific article published on 20 March 2020

Molecular evidence for the involvement of PPAR-δ and PPAR-γ in anti-inflammatory and neuroprotective activities of palmitoylethanolamide after spinal cord trauma.

scientific article published on February 2013

Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Inhibitor as a Novel Therapeutic Tool for Lung Injury

scientific article published on 20 October 2020

N-Palmitoylethanolamide-Oxazoline Protects against Middle Cerebral Artery Occlusion Injury in Diabetic Rats by Regulating the SIRT1 Pathway

scientific article published on 29 September 2019

N-Palmitoylethanolamine-Oxazoline (PEA-OXA) as a New Therapeutic Strategy to Control Neuroinflammation: Neuroprotective Effects in Experimental Models of Spinal Cord and Brain Injury.

scientific article published on 17 January 2017

N-Palmitoylethanolamine-oxazoline (PEA-OXA): A new therapeutic strategy to reduce neuroinflammation, oxidative stress associated to vascular dementia in an experimental model of repeated bilateral common carotid arteries occlusion

scientific article published on 17 January 2019

N-acetyl-L-cysteine reduces Leishmania amazonensis-induced inflammation in BALB/c mice

scientific article published on 13 January 2020

N-palmitoylethanolamide Prevents Parkinsonian Phenotypes in Aged Mice.

scientific article published on 19 March 2018

Neuroinflammation and Immunity: A New Pharmacological Target in Depression.

scientific article published on 20 March 2016

Neuroinflammation and neurohormesis in the pathogenesis of Alzheimer’s disease and Alzheimer-linked pathologies: modulation by nutritional mushrooms

scientific article

Neuroprotective Effect of Artesunate in Experimental Model of Traumatic Brain Injury

scientific article published on 31 July 2018

Neuroprotective Effects of Temsirolimus in Animal Models of Parkinson's Disease

scientific article published on 29 March 2017

New therapeutic strategy for mood disorders.

scientific article published on January 2011

Novel Combination of COX-2 Inhibitor and Antioxidant Therapy for Modulating Oxidative Stress Associated with Intestinal Ischemic Reperfusion Injury and Endotoxemia

scientific article published on 28 September 2020

Oral Supplementation with Ultramicronized Palmitoylethanolamide for Joint Disease and Lameness Management in Four Jumping Horses: A Case Report

scientific article published on 21 August 2020

Oral Ultramicronized Palmitoylethanolamide: Plasma and Tissue Levels and Spinal Anti-hyperalgesic Effect.

scientific article published on 20 March 2018

Osteoporosis and alzheimer pathology: Role of cellular stress response and hormetic redox signaling in aging and bone remodeling

scientific article

PPAR-α Modulates the Anti-Inflammatory Effect of Melatonin in the Secondary Events of Spinal Cord Injury.

scientific article published on 29 September 2016

Palmitoylethanolamide and Related ALIAmides: Prohomeostatic Lipid Compounds for Animal Health and Wellbeing

scientific article published on 16 June 2020

Plastics occurrence in the gastrointestinal tract of Zeus faber and Lepidopus caudatus from the Tyrrhenian Sea

scientific article published on 09 July 2019

Protective Effect of Epigallocatechin-3-Gallate (EGCG) in Diseases with Uncontrolled Immune Activation: Could Such a Scenario Be Helpful to Counteract COVID-19?

scientific article published on 21 July 2020

Protective Effect of Hydroxytyrosol on LPS-Induced Inflammation and Oxidative Stress in Bovine Endometrial Epithelial Cell Line

scientific article published on 23 October 2020

Protective Effect of Silibinin on Lipopolysaccharide-Induced Inflammatory Responses in Equine Peripheral Blood Mononuclear Cells, an In Vitro Study

scientific article published on 03 November 2020

Protective Effects of Ultramicronized Palmitoylethanolamide (PEA-um) in Myocardial Ischaemia and Reperfusion Injury in VIVO

scientific article published on 01 August 2016

Protective effect of polyphenols in an inflammatory process associated with experimental pulmonary fibrosis in mice.

scientific article published in September 2015

Protective effects of Colomast®, A New Formulation of Adelmidrol and Sodium Hyaluronate, in A Mouse Model of Acute Restraint Stress

scientific article published on 30 October 2020

Reduced adult neurogenesis and altered emotional behaviors in autoimmune-prone B-cell activating factor transgenic mice.

scientific article

Reduction of ischemic brain injury by administration of palmitoylethanolamide after transient middle cerebral artery occlusion in rats

scientific article published on 13 August 2012

Role of Metabotropic Glutamate Receptors in Neurological Disorders

scientific article published on 08 February 2019

Safety and efficacy of a new micronized formulation of the ALIAmide palmitoylglucosamine in preclinical models of inflammation and osteoarthritis pain

scientific article published on 28 November 2019

Susceptibility of erythrocytes from different sources to xenobiotics-induced lysis

scientific article published on 26 March 2019

The Antioxidant and Anti-Inflammatory Properties of Anacardium occidentale L. Cashew Nuts in a Mouse Model of Colitis

scientific article published on 20 March 2020

The Association of Palmitoylethanolamide with Luteolin Decreases Autophagy in Spinal Cord Injury.

scientific article

The Effects of 1-Hz rTMS on Emotional Behavior and Dendritic Complexity of Mature and Newly Generated Dentate Gyrus Neurons in Male Mice

scientific article published on 08 June 2020

The Neuroprotective Effect of Dimethyl Fumarate in an MPTP-Mouse Model of Parkinson's Disease: Involvement of Reactive Oxygen Species/Nuclear Factor-κB/Nuclear Transcription Factor Related to NF-E2.

scientific article published on 23 December 2016

The Protective Effects of Pre- and Post-Administration of Micronized Palmitoylethanolamide Formulation on Postoperative Pain in Rats

scientific article published on 18 October 2020

The anti-inflammatory effects of palmitoylethanolamide (PEA) on endotoxin-induced uveitis in rats

scientific article published on 28 April 2015

The association of adelmidrol with sodium hyaluronate displays beneficial properties against bladder changes following spinal cord injury in mice

scientific article published in PLoS ONE

The neuroprotective effects of micronized PEA (PEA-m) formulation on diabetic peripheral neuropathy in mice

scientific article published on 25 July 2019

The role of Annexin A1 and formyl peptide receptor 2/3 signaling on chronic corticosterone-induced depression-like behaviors and impairment in hippocampal-dependent memory

scientific article published on 06 January 2020

Therapeutic Efficacy of Palmitoylethanolamide and Its New Formulations in Synergy with Different Antioxidant Molecules Present in Diets

scientific article published on 11 September 2019

Traumatic Brain Injury Leads to Development of Parkinson's Disease Related Pathology in Mice

scientific article published on 13 October 2016

Traumatic brain injury: oxidative stress and neuroprotection.

scientific article published on 10 May 2013

Ultramicronized Palmitoylethanolamide and Paracetamol, a New Association to Relieve Hyperalgesia and Pain in a Sciatic Nerve Injury Model in Rat

scientific article published on 15 May 2020

Ultramicronized palmitoylethanolamide (PEA-um(®)) in the treatment of idiopathic pulmonary fibrosis.

scientific article published on 8 July 2016

Use of contrast-enhanced ultrasound for assessment of nodular lymphoid hyperplasia (NLH) in canine spleen.

scientific article

n-3 fatty acids: role in neurogenesis and neuroplasticity

scientific article published on January 2013

n−3 fatty acids prevent impairment of neurogenesis and synaptic plasticity in B-cell activating factor (BAFF) transgenic mice

scientific article published on December 28, 2011