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List of works by Jamie Spangler

A strategy for the selection of monovalent antibodies that span protein dimer interfaces

scientific article published on 06 August 2019

Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms.

scientific article published on May 2015

Author Correction: Engineering cytokine therapeutics

scientific article published in 2023

Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling.

scientific article

Effect of pathogenic cysteine mutations on FGFR3 transmembrane domain dimerization in detergents and lipid bilayers.

scientific article published on 11 September 2007

Engineering a Single-Agent Cytokine/Antibody Fusion That Selectively Expands Regulatory T Cells for Autoimmune Disease Therapy

scientific article published on 13 August 2018

Engineering cytokine therapeutics

scientific article published in 2023

IgM autoantibodies recognizing ACE2 are associated with severe COVID-19

scientific article published on 15 October 2020

Insights into cytokine-receptor interactions from cytokine engineering

scientific article

Interleukin-2 activity can be fine tuned with engineered receptor signaling clamps.

scientific article

Multifarious determinants of cytokine receptor signaling specificity.

scientific article published on January 2014

Structure-Guided Molecular Engineering of a Vascular Endothelial Growth Factor Antagonist to Treat Retinal Diseases

scientific article published on 31 July 2020

Synthekines are surrogate cytokine and growth factor agonists that compel signaling through non-natural receptor dimers.

scientific article

Triepitopic Antibody Fusions Inhibit Cetuximab-Resistant BRAF and KRAS Mutant Tumors via EGFR Signal Repression ⬇️

scientific article published on June 15, 2012

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