List of works - Timothy J Knowles

A method for detergent-free isolation of membrane proteins in their local lipid environment. ⬇️

scientific article

A novel pathway for outer membrane protein biogenesis in Gram-negative bacteria

scientific article

An acid-compatible co-polymer for the solubilization of membranes and proteins into lipid bilayer-containing nanoparticles.

scientific article published in June 2018

BTN3A1 Discriminates γδ T Cell Phosphoantigens from Nonantigenic Small Molecules via a Conformational Sensor in Its B30.2 Domain

scientific article

Binding of the periplakin linker requires vimentin acidic residues D176 and E187

scientific article published on 21 February 2020

Characterization of a Putative Receptor Binding Surface on Skint-1, a Critical Determinant of Dendritic Epidermal T Cell Selection.

scientific article

Cross-species chimeras reveal BamA POTRA and β-barrel domains must be fine-tuned for efficient OMP insertion

scientific article

Encapsulated membrane proteins: A simplified system for molecular simulation.

scientific article published on 2 March 2016

Evidence for phospholipid export from the bacterial inner membrane by the Mla ABC transport system

scientific article published on 24 June 2019

Fold and function of polypeptide transport-associated domains responsible for delivering unfolded proteins to membranes

scientific article

G-protein coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent.

scientific article published on 16 April 2015

MCE domain proteins: conserved inner membrane lipid-binding proteins required for outer membrane homeostasis.

scientific article published on 17 August 2017

Mechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin.

scientific article published on 3 March 2016

Membrane protein architects: the role of the BAM complex in outer membrane protein assembly.

scientific article

Membrane protein extraction and purification using styrene-maleic acid (SMA) copolymer: effect of variations in polymer structure.

scientific article published on 30 September 2016

Minichaperone (GroEL191-345) mediated folding of MalZ proceeds by binding and release of native and functional intermediates

scientific article published on 02 June 2018

Mutational and topological analysis of the Escherichia coli BamA protein.

scientific article

Production of membrane proteins without cells or detergents.

scientific article published on 21 July 2010

SMA-PAGE: A new method to examine complexes of membrane proteins using SMALP nano-encapsulation and native gel electrophoresis

scientific article published on 28 May 2019

Secondary structure and (1)H, (13)C and (15)N backbone resonance assignments of BamC, a component of the outer membrane protein assembly machinery in Escherichia coli.

scientific article

Secondary structure and (1)H, (13)C and (15)N resonance assignments of Skint-1: a selecting ligand for a murine γδ T cell subset implicated in tumour suppression

scientific article

Secondary structure and 1H, 13C and 15N resonance assignments of the Escherichia coli YaeT POTRA domain.

scientific article published on 21 July 2007

Structural Investigations of Protein-Lipid Complexes Using Neutron Scattering

scientific article published on 01 January 2019

Structural analysis of a nanoparticle containing a lipid bilayer used for detergent-free extraction of membrane proteins

scientific article published on 23 October 2014

Structure and function of BamE within the outer membrane and the β-barrel assembly machine

scientific article

The C-terminal tail of the bacterial translocation ATPase SecA modulates its activity

scientific article published on 27 June 2019

The nonlinear structure of the desmoplakin plakin domain and the effects of cardiomyopathy-linked mutations

scientific article (publication date: 2 September 2011)

YraP Contributes to Cell Envelope Integrity and Virulence of Salmonella enterica Serovar Typhimurium

scientific article published on 25 October 2018

List of works by Timothy J Knowles

A method for detergent-free isolation of membrane proteins in their local lipid environment. ⬇️

A novel pathway for outer membrane protein biogenesis in Gram-negative bacteria

An acid-compatible co-polymer for the solubilization of membranes and proteins into lipid bilayer-containing nanoparticles.

BTN3A1 Discriminates γδ T Cell Phosphoantigens from Nonantigenic Small Molecules via a Conformational Sensor in Its B30.2 Domain

Binding of the periplakin linker requires vimentin acidic residues D176 and E187

Characterization of a Putative Receptor Binding Surface on Skint-1, a Critical Determinant of Dendritic Epidermal T Cell Selection.

Cross-species chimeras reveal BamA POTRA and β-barrel domains must be fine-tuned for efficient OMP insertion

Encapsulated membrane proteins: A simplified system for molecular simulation.

Evidence for phospholipid export from the bacterial inner membrane by the Mla ABC transport system

Fold and function of polypeptide transport-associated domains responsible for delivering unfolded proteins to membranes

G-protein coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent.

MCE domain proteins: conserved inner membrane lipid-binding proteins required for outer membrane homeostasis.

Mechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin.

Membrane protein architects: the role of the BAM complex in outer membrane protein assembly.

Membrane protein extraction and purification using styrene-maleic acid (SMA) copolymer: effect of variations in polymer structure.

Minichaperone (GroEL191-345) mediated folding of MalZ proceeds by binding and release of native and functional intermediates

Mutational and topological analysis of the Escherichia coli BamA protein.

Production of membrane proteins without cells or detergents.

SMA-PAGE: A new method to examine complexes of membrane proteins using SMALP nano-encapsulation and native gel electrophoresis

Secondary structure and (1)H, (13)C and (15)N backbone resonance assignments of BamC, a component of the outer membrane protein assembly machinery in Escherichia coli.

Secondary structure and (1)H, (13)C and (15)N resonance assignments of Skint-1: a selecting ligand for a murine γδ T cell subset implicated in tumour suppression

Secondary structure and 1H, 13C and 15N resonance assignments of the Escherichia coli YaeT POTRA domain.

Structural Investigations of Protein-Lipid Complexes Using Neutron Scattering

Structural analysis of a nanoparticle containing a lipid bilayer used for detergent-free extraction of membrane proteins

Structure and function of BamE within the outer membrane and the β-barrel assembly machine

The C-terminal tail of the bacterial translocation ATPase SecA modulates its activity

The nonlinear structure of the desmoplakin plakin domain and the effects of cardiomyopathy-linked mutations

YraP Contributes to Cell Envelope Integrity and Virulence of Salmonella enterica Serovar Typhimurium