List of works by Sally A Frautschy

A Novel Model of Mixed Vascular Dementia Incorporating Hypertension in a Rat Model of Alzheimer's Disease

scientific article published on 24 October 2019

A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model.

scientific article

A potential role of the curry spice curcumin in Alzheimer's disease

scientific article

A sensitive LC-MS assay using derivatization with boron trifluoride to quantify curcuminoids in biological samples

scientific article published on 17 February 2020

A time course for the focal elevation of synthesis of basic fibroblast growth factor and one of its high-affinity receptors (flg) following a localized cortical brain injury ⬇️

scientific article published on October 1, 1992

Alzheimer's amyloid story finds its star.

scientific article published in August 2006

Aminopyridazines inhibit beta-amyloid-induced glial activation and neuronal damage in vivo

scientific article published in November 2004

Antibiotics in microbial ecology : Isolation and structure assignment of several new antibacterial compounds from the insect-symbiotic bacteriaXenorhabdus spp.

scientific article

Antibodies against beta-amyloid reduce Abeta oligomers, glycogen synthase kinase-3beta activation and tau phosphorylation in vivo and in vitro.

scientific article published on February 2006

Apolipoprotein E isotype-dependent modulation of microRNA-146a in plasma and brain

scientific article published on 8 June 2016

Beta-amyloid oligomers induce phosphorylation of tau and inactivation of insulin receptor substrate via c-Jun N-terminal kinase signaling: suppression by omega-3 fatty acids and curcumin.

scientific article

C-terminal turn stability determines assembly differences between Aβ40 and Aβ42

scientific article published on 12 November 2012

Cat and mouse

scientific article

Clinical development of curcumin in neurodegenerative disease.

scientific article published on June 2015

Commentary on "Cytoskeletal modulators and pleiotropic strategies for Alzheimer drug discovery." Pleiotropic approaches to Alzheimer's and other diseases of aging.

scientific article published in October 2006

Curcumin Ameliorates Neuroinflammation, Neurodegeneration, and Memory Deficits in p25 Transgenic Mouse Model that Bears Hallmarks of Alzheimer's Disease.

scientific article published on 12 October 2017

Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

scientific article (publication date: 18 February 2005)

Curcumin restores innate immune Alzheimer's disease risk gene expression to ameliorate Alzheimer pathogenesis

scientific article published on 02 April 2019

Curcumin structure-function, bioavailability, and efficacy in models of neuroinflammation and Alzheimer's disease

scientific article

Curcumin suppresses soluble tau dimers and corrects molecular chaperone, synaptic, and behavioral deficits in aged human tau transgenic mice

scientific article

Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity

scientific article published in March 2008

DHA may prevent age-related dementia

scientific article published on 24 February 2010

Dietary DHA supplementation in an APP/PS1 transgenic rat model of AD reduces behavioral and Aβ pathology and modulates Aβ oligomerization

scientific article

Dietary fatty acids and the aging brain

scientific article published on December 2010

Dietary n-3 polyunsaturated fatty acid depletion activates caspases and decreases NMDA receptors in the brain of a transgenic mouse model of Alzheimer's disease

scientific article published in August 2005

Docosahexaenoic acid protects from amyloid and dendritic pathology in an Alzheimer's disease mouse model

scientific article published on January 2006

Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model

scientific article

Estrogen augments hypothalamicβ-endorphin secretion and activates an inhibitoryβ-endorphin short-loop feedback system

scientific article published on 01 April 1995

Evidence of Abeta- and transgene-dependent defects in ERK-CREB signaling in Alzheimer's models

scientific article published on 30 August 2007

GSK3 inhibitors show benefits in an Alzheimer's disease (AD) model of neurodegeneration but adverse effects in control animals

scientific article

Ibuprofen suppresses interleukin-1beta induction of pro-amyloidogenic alpha1-antichymotrypsin to ameliorate beta-amyloid (Abeta) pathology in Alzheimer's models

scientific article published in June 2005

Improvement of neuropathology and transcriptional deficits in CAG 140 knock-in mice supports a beneficial effect of dietary curcumin in Huntington's disease.

scientific article

Insulin-degrading enzyme as a downstream target of insulin receptor signaling cascade: implications for Alzheimer's disease intervention.

scientific article published in December 2004

Intracellular Abeta is increased by okadaic acid exposure in transfected neuronal and non-neuronal cell lines

scientific article published on March 2002

Lack of efficacy of curcumin on neurodegeneration in the mouse model of Niemann-Pick C1.

scientific article published on 17 December 2011

Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging

scientific article

Mechanisms of action of non-steroidal anti-inflammatory drugs for the prevention of Alzheimer's disease.

scientific article published on April 2010

Modeling Mixed Vascular and Alzheimer's Dementia Using Focal Subcortical Ischemic Stroke in Human ApoE4-TR:5XFAD Transgenic Mice

scientific article published on 21 February 2020

Molecular chaperone dysfunction in neurodegenerative diseases and effects of curcumin.

scientific article

NSAID and antioxidant prevention of Alzheimer's disease: lessons from in vitro and animal models.

scientific article

Neuroinflammation in Alzheimer's disease

scientific article (publication date: April 2015)

Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer's disease.

scientific article published on 6 March 2018

Neuroprotective effects of curcumin

scientific article published on January 2007

Omega-3 fatty acid docosahexaenoic acid increases SorLA/LR11, a sorting protein with reduced expression in sporadic Alzheimer's disease (AD): relevance to AD prevention

scientific article published on December 2007

Omega-3 fatty acids and dementia.

scientific article

Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study

scientific article published on 29 October 2012

PAK in Alzheimer disease, Huntington disease and X-linked mental retardation

scientific article

Parallel age-associated changes in brain and plasma neuronal pentraxin receptor levels in a transgenic APP/PS1 rat model of Alzheimer's disease.

scientific article

Pituitary Portal Plasma Levels of Oxytocin during the Estrous Cycle, Lactation, and Hyperprolactinemia ⬇️

scientific article published on June 12, 1992

Prevention of Alzheimer's disease: Omega-3 fatty acid and phenolic anti-oxidant interventions

scientific article

Protection of primary neurons and mouse brain from Alzheimer's pathology by molecular tweezers

scientific article

Reduction of SorLA/LR11, a sorting protein limiting beta-amyloid production, in Alzheimer disease cerebrospinal fluid

scientific article published on April 2009

Retinal amyloid pathology and proof-of-concept imaging trial in Alzheimer's disease

scientific article published on 17 August 2017

Role of LRP in TGFbeta2-mediated neuronal uptake of Abeta and effects on memory.

scientific article

Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease.

scientific article published on 15 January 2006

Sectoral segmentation of retinal amyloid imaging in subjects with cognitive decline

scientific article published on 28 September 2020

Short-term total sleep deprivation in the rat increases antioxidant responses in multiple brain regions without impairing spontaneous alternation behavior.

scientific article

Solvent effects on beta protein toxicity in vivo

scientific article published on September 1, 1992

Tetrahydrocurcumin in plasma and urine: quantitation by high performance liquid chromatography

scientific article published in September 2005

The Novel Omega-6 Fatty Acid Docosapentaenoic Acid Positively Modulates Brain Innate Immune Response for Resolving Neuroinflammation at Early and Late Stages of Humanized APOE-Based Alzheimer's Disease Models

scientific article published on 16 October 2020

The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse.

scientific article

The role of insulin and neurotrophic factor signaling in brain aging and Alzheimer's Disease

scientific article published on 17 October 2006

Thinking outside the box about COX-1 in Alzheimer's disease

scientific article published on 2 March 2010

Use of copper and insulin-resistance to accelerate cognitive deficits and synaptic protein loss in a rat Abeta-infusion Alzheimer's disease model

scientific article published on December 2008

What was lost in translation in the DHA trial is whom you should intend to treat

scientific article

Why pleiotropic interventions are needed for Alzheimer's disease.

scientific article

[F-18]FDDNP microPET imaging correlates with brain Aβ burden in a transgenic rat model of Alzheimer disease: effects of aging, in vivo blockade, and anti-Aβ antibody treatment.

scientific article

beta-Amyloid infusion results in delayed and age-dependent learning deficits without role of inflammation or beta-amyloid deposits.

scholarly article

p21-activated kinase-aberrant activation and translocation in Alzheimer disease pathogenesis

scientific journal article

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