List of works - Janez Ilas

3,4-Dihydro-2H-1,4-benzoxazine derivatives combining thrombin inhibitory and glycoprotein IIb/IIIa receptor antagonistic activity as a novel class of antithrombotic compounds with dual function.

scientific article published on 27 August 2008

A road map for prioritizing warheads for cysteine targeting covalent inhibitors

scientific article published on 06 October 2018

ATP-competitive DNA gyrase and topoisomerase IV inhibitors as antibacterial agents

scientific article published on 06 February 2019

An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors

scientific article published on 10 February 2019

Antimicrobial activity of the marine alkaloids, clathrodin and oroidin, and their synthetic analogues

scientific article published on 14 February 2014

Discovery of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site

scientific article published on 8 July 2015

Discovery of d-amino acid oxidase inhibitors based on virtual screening against the lid-open enzyme conformation.

scientific article published on 20 April 2018

Discovery of isatin and 1H-indazol-3-ol derivatives as d-amino acid oxidase (DAAO) inhibitors

scientific article published on 08 February 2018

Discovery of substituted oxadiazoles as a novel scaffold for DNA gyrase inhibitors.

scientific article published on 22 February 2017

Dual Inhibitors of Human DNA Topoisomerase II and Other Cancer-Related Targets

scientific article published on 21 October 2019

Heterocyclic electrophiles as new MurA inhibitors

scientific article published on 21 November 2018

Hybrid Inhibitors of DNA Gyrase A and B: Design, Synthesis and Evaluation

scientific article published on 22 December 2020

Inhibition of biofilm formation by conformationally constrained indole-based analogues of the marine alkaloid oroidin

scientific article published on 08 April 2014

Linker-switch approach towards new ATP binding site inhibitors of DNA gyrase B.

scientific article

Multitarget antithrombotic drugs.

scientific article

New N-phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATPase inhibitors of DNA gyrase.

scientific article

New N-phenyl-4,5-dibromopyrrolamides as DNA gyrase B inhibitors

scientific article published on 20 May 2019

On the Stability and Degradation Pathways of Venetoclax under Stress Conditions

scientific article published on 07 July 2020

Peptides and pseudopeptides incorporating D-Phe-Pro-Arg and Arg-Gly-Asp lead sequences as potential antithrombotic agents.

scientific article published in August 2008

Rational design of balanced dual-targeting antibiotics with limited resistance

scientific article published on 05 October 2020

Structure-activity relationships and molecular docking studies of chromene and chromene based azo chromophores: A novel series of potent antimicrobial and anticancer agents

scientific article

Substituted 4-phenyl-2-aminoimidazoles and 4-phenyl-4,5-dihydro-2-aminoimidazoles as voltage-gated sodium channel modulators

scientific article

Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors

scientific article

Synthesis and Evaluation of Spumigin Analogues Library with Thrombin Inhibitory Activity

scientific article published on 27 October 2018

Thrombin inhibitors with lipid peroxidation and lipoxygenase inhibitory activities

scientific article published on 25 June 2011

List of works by Janez Ilas

3,4-Dihydro-2H-1,4-benzoxazine derivatives combining thrombin inhibitory and glycoprotein IIb/IIIa receptor antagonistic activity as a novel class of antithrombotic compounds with dual function.

A road map for prioritizing warheads for cysteine targeting covalent inhibitors

ATP-competitive DNA gyrase and topoisomerase IV inhibitors as antibacterial agents

An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors

Antimicrobial activity of the marine alkaloids, clathrodin and oroidin, and their synthetic analogues

Discovery of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site

Discovery of d-amino acid oxidase inhibitors based on virtual screening against the lid-open enzyme conformation.

Discovery of isatin and 1H-indazol-3-ol derivatives as d-amino acid oxidase (DAAO) inhibitors

Discovery of substituted oxadiazoles as a novel scaffold for DNA gyrase inhibitors.

Dual Inhibitors of Human DNA Topoisomerase II and Other Cancer-Related Targets

Heterocyclic electrophiles as new MurA inhibitors

Hybrid Inhibitors of DNA Gyrase A and B: Design, Synthesis and Evaluation

Inhibition of biofilm formation by conformationally constrained indole-based analogues of the marine alkaloid oroidin

Linker-switch approach towards new ATP binding site inhibitors of DNA gyrase B.

Multitarget antithrombotic drugs.

New N-phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATPase inhibitors of DNA gyrase.

New N-phenyl-4,5-dibromopyrrolamides as DNA gyrase B inhibitors

On the Stability and Degradation Pathways of Venetoclax under Stress Conditions

Peptides and pseudopeptides incorporating D-Phe-Pro-Arg and Arg-Gly-Asp lead sequences as potential antithrombotic agents.

Rational design of balanced dual-targeting antibiotics with limited resistance

Structure-activity relationships and molecular docking studies of chromene and chromene based azo chromophores: A novel series of potent antimicrobial and anticancer agents

Substituted 4-phenyl-2-aminoimidazoles and 4-phenyl-4,5-dihydro-2-aminoimidazoles as voltage-gated sodium channel modulators

Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors

Synthesis and Evaluation of Spumigin Analogues Library with Thrombin Inhibitory Activity

Thrombin inhibitors with lipid peroxidation and lipoxygenase inhibitory activities