List of works - Andrew S MacDonald

1,25-Dihydroxyvitamin D3-Conditioned CD11c+ Dendritic Cells are Effective Initiators of CNS Autoimmune Disease.

scientific article

A central role for hepatic conventional dendritic cells in supporting Th2 responses during helminth infection

scientific article published on 11 December 2015

A unique DNA methylation signature defines a population of IFN-γ/IL-4 double-positive T cells during helminth infection.

scientific article

Alternative activation of macrophages by filarial nematodes is MyD88-independent.

scientific article published on 21 July 2012

Alternatively activated dendritic cells regulate CD4+ T-cell polarization in vitro and in vivo

scientific article

Chronic infection drives expression of the inhibitory receptor CD200R, and its ligand CD200, by mouse and human CD4 T cells

scientific article (publication date: 2012)

Concurrent bacterial stimulation alters the function of helminth-activated dendritic cells, resulting in IL-17 induction.

scientific article

Cutting Edge: Th2 Response Induction by Dendritic Cells: A Role for CD40 ⬇️

scientific article published on January 15, 2002

Dendritic cell expression of the Notch ligandjagged2 is not essential for Th2 response inductionin vivo

article

Dermal IRF4+ dendritic cells and monocytes license CD4+ T helper cells to distinct cytokine profiles

scientific article published on 06 November 2020

Full development of Th2 immunity requires both innate and adaptive sources of CD154.

scientific article published in June 2008

Human NK Cells Lyse Th2-Polarizing Dendritic Cells via NKp30 and DNAM-1

scientific article published on 17 August 2018

ICOS controls Foxp3(+) regulatory T-cell expansion, maintenance and IL-10 production during helminth infection

scientific article published on 31 January 2013

IL-4-producing ILC2s are required for the differentiation of TH2 cells following Heligmosomoides polygyrus infection.

scientific article published on 17 February 2016

Integrin α4β1 controls G9a activity that regulates epigenetic changes and nuclear properties required for lymphocyte migration.

scientific article published on 10 December 2015

Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation

scientific article

Loss of beta2-integrin-mediated cytoskeletal linkage reprogrammes dendritic cells to a mature migratory phenotype.

scientific article

Mapping the Influence of the Gut Microbiota on Small Molecules across the Microbiome Gut Brain Axis

scientific article published on 09 March 2022

Modulation of dendritic cell alternative activation and function by the vitamin A metabolite retinoic acid.

scientific article

Plasmacytoid Dendritic Cells Facilitate Th Cell Cytokine Responses throughout <i>Schistosoma mansoni</i> Infection

scientific article published on 30 August 2021

Profound suppression of cellular proliferation mediated by the secretions of nematodes ⬇️

scientific article published on May 1, 1998

RNA:DNA hybrids are a novel molecular pattern sensed by TLR9.

scientific article published on 10 February 2014

SOX9 predicts progression toward cirrhosis in patients while its loss protects against liver fibrosis.

scientific article published on 6 November 2017

Schistosoma mansoni Larvae Do Not Expand or Activate Foxp3+ Regulatory T Cells during Their Migratory Phase.

scientific article

Schistosoma mansoni infection is associated with quantitative and qualitative modifications of the mammalian intestinal microbiota

scientific article published in Scientific Reports

TLR-4 ligation of dendritic cells is sufficient to drive pathogenic T cell function in experimental autoimmune encephalomyelitis.

scientific article published on 30 October 2012

Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues

scientific article published on 09 July 2020

The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung.

scientific article published on 21 January 2015

The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an 'M2' phenotype in response to Th2 immunologic challenge.

scientific article published on 7 February 2015

The circadian regulator BMAL1 programmes responses to parasitic worm infection via a dendritic cell clock.

scientific article

The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation

scientific article published on 01 April 2019

The major secreted protein of the whipworm parasite tethers to matrix and inhibits interleukin-13 function

article

Unconventional maturation of dendritic cells induced by particles from the laminated layer of larval Echinococcus granulosus

scientific article

List of works by Andrew S MacDonald

1,25-Dihydroxyvitamin D3-Conditioned CD11c+ Dendritic Cells are Effective Initiators of CNS Autoimmune Disease.

A central role for hepatic conventional dendritic cells in supporting Th2 responses during helminth infection

A unique DNA methylation signature defines a population of IFN-γ/IL-4 double-positive T cells during helminth infection.

Alternative activation of macrophages by filarial nematodes is MyD88-independent.

Alternatively activated dendritic cells regulate CD4+ T-cell polarization in vitro and in vivo

Chronic infection drives expression of the inhibitory receptor CD200R, and its ligand CD200, by mouse and human CD4 T cells

Concurrent bacterial stimulation alters the function of helminth-activated dendritic cells, resulting in IL-17 induction.

Cutting Edge: Th2 Response Induction by Dendritic Cells: A Role for CD40 ⬇️

Dendritic cell expression of the Notch ligandjagged2 is not essential for Th2 response inductionin vivo

Dermal IRF4+ dendritic cells and monocytes license CD4+ T helper cells to distinct cytokine profiles

Full development of Th2 immunity requires both innate and adaptive sources of CD154.

Human NK Cells Lyse Th2-Polarizing Dendritic Cells via NKp30 and DNAM-1

ICOS controls Foxp3(+) regulatory T-cell expansion, maintenance and IL-10 production during helminth infection

IL-4-producing ILC2s are required for the differentiation of TH2 cells following Heligmosomoides polygyrus infection.

Integrin α4β1 controls G9a activity that regulates epigenetic changes and nuclear properties required for lymphocyte migration.

Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation

Loss of beta2-integrin-mediated cytoskeletal linkage reprogrammes dendritic cells to a mature migratory phenotype.

Mapping the Influence of the Gut Microbiota on Small Molecules across the Microbiome Gut Brain Axis

Modulation of dendritic cell alternative activation and function by the vitamin A metabolite retinoic acid.

Plasmacytoid Dendritic Cells Facilitate Th Cell Cytokine Responses throughout <i>Schistosoma mansoni</i> Infection

Profound suppression of cellular proliferation mediated by the secretions of nematodes ⬇️

RNA:DNA hybrids are a novel molecular pattern sensed by TLR9.

SOX9 predicts progression toward cirrhosis in patients while its loss protects against liver fibrosis.

Schistosoma mansoni Larvae Do Not Expand or Activate Foxp3+ Regulatory T Cells during Their Migratory Phase.

Schistosoma mansoni infection is associated with quantitative and qualitative modifications of the mammalian intestinal microbiota

TLR-4 ligation of dendritic cells is sufficient to drive pathogenic T cell function in experimental autoimmune encephalomyelitis.

Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues

The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung.

The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an 'M2' phenotype in response to Th2 immunologic challenge.

The circadian regulator BMAL1 programmes responses to parasitic worm infection via a dendritic cell clock.

The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation

The major secreted protein of the whipworm parasite tethers to matrix and inhibits interleukin-13 function

Unconventional maturation of dendritic cells induced by particles from the laminated layer of larval Echinococcus granulosus