List of works - Thomas P C Dorlo

A Semi-Mechanistic Population Pharmacokinetic/Pharmacodynamic Model of Bortezomib in Pediatric Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia

scientific article published on 01 February 2020

A poor-quality generic drug for the treatment of visceral leishmaniasis: a case report and appeal

scientific article

Adherence to miltefosine treatment for visceral leishmaniasis under routine conditions in Nepal.

scientific article published on 30 November 2012

Assessment of blood-brain barrier penetration of miltefosine used to treat a fatal case of granulomatous amebic encephalitis possibly caused by an unusual Balamuthia mandrillaris strain

scientific article

Characterization and identification of suspected counterfeit miltefosine capsules

scientific article published on 18 January 2012

Clinical Pharmacokinetics of Systemically Administered Antileishmanial Drugs.

scientific article

Clinical Trial Simulation To Optimize Trial Design for Fludarabine Dosing Strategies in Allogeneic Hematopoietic Cell Transplantation

scientific article published on 19 January 2020

Comment on: Cutaneous and mucocutaneous leishmaniasis in Tigray, northern Ethiopia: clinical aspects and therapeutic concerns.

scientific article published in January 2010

Development and validation of a quantitative assay for the measurement of miltefosine in human plasma by liquid chromatography-tandem mass spectrometry.

scientific article published on 20 February 2008

Different liposomal amphotericin B formulations for visceral leishmaniasis

scientific article published on 23 July 2014

Does Older Age Lead to Higher Risk for Neutropenia in Patients Treated with Paclitaxel?

scientific article published on 15 October 2019

Dose Reduction of Caspofungin in Intensive Care Unit Patients with Child Pugh B Will Result in Suboptimal Exposure.

scientific article published on 09 December 2015

Dynamics of parasite clearance in cutaneous leishmaniasis patients treated with miltefosine

scientific article

Efficacy and Safety of AmBisome in Combination with Sodium Stibogluconate or Miltefosine and Miltefosine Monotherapy for African Visceral Leishmaniasis: Phase II Randomized Trial

scientific article

Exposure to Docetaxel in the Elderly Patient Population: a Population Pharmacokinetic Study

scientific article published on 15 November 2019

Fludarabine exposure in the conditioning prior to allogeneic hematopoietic cell transplantation predicts outcomes

scientific article published on 01 July 2019

Functional Validation of ABCA3 as a Miltefosine Transporter in Human Macrophages: IMPACT ON INTRACELLULAR SURVIVAL OF LEISHMANIA (VIANNIA) PANAMENSIS.

scientific article published on 22 February 2016

Geographical Variability in Paromomycin Pharmacokinetics Does Not Explain Efficacy Differences between Eastern African and Indian Visceral Leishmaniasis Patients

scientific article published on 09 June 2021

Immunomodulatory Therapy of Visceral Leishmaniasis in Human Immunodeficiency Virus-Coinfected Patients.

scientific article published in January 2017

Impact of Older Age on the Exposure of Paclitaxel: a Population Pharmacokinetic Study

scientific article published on 07 January 2019

Lack of Clinical Pharmacokinetic Studies to Optimize the Treatment of Neglected Tropical Diseases: A Systematic Review

scientific article

Letter by Dorlo Regarding Article, "Acupuncture Therapy and Incidence of Depression After Stroke".

scientific article

Low antileishmanial drug exposure in HIV-positive visceral leishmaniasis patients on antiretrovirals: an Ethiopian cohort study

scientific article published on 01 April 2021

Macrophage Activation Marker Neopterin: A Candidate Biomarker for Treatment Response and Relapse in Visceral Leishmaniasis.

scientific article

Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis ⬇️

scientific article published on July 24, 2012

Optimal Dosing of Miltefosine in Children and Adults with Visceral Leishmaniasis ⬇️

scientific article published on May 14, 2012

Pentamidine dosage: a base/salt confusion

scientific article

Pharmacodynamic modeling of cardiac biomarkers in breast cancer patients treated with anthracycline and trastuzumab regimens

scientific article published on 10 February 2018

Pharmacokinetic Targets for Therapeutic Drug Monitoring of Small Molecule Kinase Inhibitors in Pediatric Oncology

scientific article published on 05 February 2020

Pharmacokinetics and pharmacodynamics of oleylphosphocholine in a hamster model of visceral leishmaniasis.

scientific article published on 15 April 2016

Pharmacokinetics of Miltefosine in Children and Adults with Cutaneous Leishmaniasis.

scientific article published on 12 December 2016

Pharmacokinetics of miltefosine in Old World cutaneous leishmaniasis patients.

scientific article published on 2 June 2008

Pharmacokinetics, safety and efficacy of an allometric miltefosine regimen for the treatment of visceral leishmaniasis in Eastern African children: an open-label, phase-II clinical trial

scientific article published on 01 April 2019

Please, let notWestern quackery replace traditional medicine inAfrica ⬇️

scientific article published on December 10, 2012

Population Pharmacokinetics of Fludarabine in Children and Adults during Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation

scientific article published on 01 May 2019

Population pharmacokinetics of artemether, dihydroartemisinin and lumefantrine in Rwandese pregnant women treated for uncomplicated malaria

scientific article published on 24 September 2018

Population pharmacokinetics of levamisole in children with steroid-sensitive nephrotic syndrome

scientific article

Predictable threats to public health through delaying universal access to innovative medicines for hepatitis C: a pharmaceutical standpoint

scientific article published on 27 September 2016

Quantification of miltefosine in peripheral blood mononuclear cells by high-performance liquid chromatography-tandem mass spectrometry

scientific article

Reply to Arya and Agarwal

scientific article published on 11 June 2013

Safe mass drug administration for neglected tropical diseases

scientific article published on 01 October 2018

Safety and efficacy of miltefosine alone and in combination with sodium stibogluconate and liposomal amphotericin B for the treatment of primary visceral leishmaniasis in East Africa: study protocol for a randomized controlled trial.

scientific article

Safety and efficacy of single dose versus multiple doses of AmBisome for treatment of visceral leishmaniasis in eastern Africa: a randomised trial

scientific article (publication date: 2014)

Severe encephalopathy and polyneuropathy induced by dichloroacetate.

scientific article published on 15 July 2010

Simultaneous population pharmacokinetic modelling of plasma and intracellular PBMC miltefosine concentrations in New World cutaneous leishmaniasis and exploration of exposure-response relationships

scientific article published on 01 August 2018

Systematic Review of Host-Mediated Activity of Miltefosine in Leishmaniasis through Immunomodulation.

scientific article published on 24 June 2019

Systematic review of biomarkers to monitor therapeutic response in leishmaniasis

scientific article

The global impact of Indian generics on access to health ⬇️

scientific article published on April 1, 2013

Translational pharmacokinetic modelling and simulation for the assessment of duration of contraceptive use after treatment with miltefosine.

scientific article published on 10 May 2012

Treatment of visceral leishmaniasis: pitfalls and stewardship

scientific article published on 01 July 2016

Universal access to quality medicines: prioritisation of a-priori solutions

scientific article published on 01 November 2012

Validation and Clinical Evaluation of a Novel Method To Measure Miltefosine in Leishmaniasis Patients Using Dried Blood Spot Sample Collection.

scientific article published on 19 January 2016

Visceral leishmaniasis relapse hazard is linked to reduced miltefosine exposure in patients from Eastern Africa: a population pharmacokinetic/pharmacodynamic study.

scientific article published on 6 September 2017

Volumetric absorptive microsampling (VAMS) as an alternative to conventional dried blood spots in the quantification of miltefosine in dried blood samples.

scientific article published on 9 December 2016

List of works by Thomas P C Dorlo

A Semi-Mechanistic Population Pharmacokinetic/Pharmacodynamic Model of Bortezomib in Pediatric Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia

A poor-quality generic drug for the treatment of visceral leishmaniasis: a case report and appeal

Adherence to miltefosine treatment for visceral leishmaniasis under routine conditions in Nepal.

Assessment of blood-brain barrier penetration of miltefosine used to treat a fatal case of granulomatous amebic encephalitis possibly caused by an unusual Balamuthia mandrillaris strain

Characterization and identification of suspected counterfeit miltefosine capsules

Clinical Pharmacokinetics of Systemically Administered Antileishmanial Drugs.

Clinical Trial Simulation To Optimize Trial Design for Fludarabine Dosing Strategies in Allogeneic Hematopoietic Cell Transplantation

Comment on: Cutaneous and mucocutaneous leishmaniasis in Tigray, northern Ethiopia: clinical aspects and therapeutic concerns.

Development and validation of a quantitative assay for the measurement of miltefosine in human plasma by liquid chromatography-tandem mass spectrometry.

Different liposomal amphotericin B formulations for visceral leishmaniasis

Does Older Age Lead to Higher Risk for Neutropenia in Patients Treated with Paclitaxel?

Dose Reduction of Caspofungin in Intensive Care Unit Patients with Child Pugh B Will Result in Suboptimal Exposure.

Dynamics of parasite clearance in cutaneous leishmaniasis patients treated with miltefosine

Efficacy and Safety of AmBisome in Combination with Sodium Stibogluconate or Miltefosine and Miltefosine Monotherapy for African Visceral Leishmaniasis: Phase II Randomized Trial

Exposure to Docetaxel in the Elderly Patient Population: a Population Pharmacokinetic Study

Fludarabine exposure in the conditioning prior to allogeneic hematopoietic cell transplantation predicts outcomes

Functional Validation of ABCA3 as a Miltefosine Transporter in Human Macrophages: IMPACT ON INTRACELLULAR SURVIVAL OF LEISHMANIA (VIANNIA) PANAMENSIS.

Geographical Variability in Paromomycin Pharmacokinetics Does Not Explain Efficacy Differences between Eastern African and Indian Visceral Leishmaniasis Patients

Immunomodulatory Therapy of Visceral Leishmaniasis in Human Immunodeficiency Virus-Coinfected Patients.

Impact of Older Age on the Exposure of Paclitaxel: a Population Pharmacokinetic Study

Lack of Clinical Pharmacokinetic Studies to Optimize the Treatment of Neglected Tropical Diseases: A Systematic Review

Letter by Dorlo Regarding Article, "Acupuncture Therapy and Incidence of Depression After Stroke".

Low antileishmanial drug exposure in HIV-positive visceral leishmaniasis patients on antiretrovirals: an Ethiopian cohort study

Macrophage Activation Marker Neopterin: A Candidate Biomarker for Treatment Response and Relapse in Visceral Leishmaniasis.

Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis ⬇️

Optimal Dosing of Miltefosine in Children and Adults with Visceral Leishmaniasis ⬇️

Pentamidine dosage: a base/salt confusion

Pharmacodynamic modeling of cardiac biomarkers in breast cancer patients treated with anthracycline and trastuzumab regimens

Pharmacokinetic Targets for Therapeutic Drug Monitoring of Small Molecule Kinase Inhibitors in Pediatric Oncology

Pharmacokinetics and pharmacodynamics of oleylphosphocholine in a hamster model of visceral leishmaniasis.

Pharmacokinetics of Miltefosine in Children and Adults with Cutaneous Leishmaniasis.

Pharmacokinetics of miltefosine in Old World cutaneous leishmaniasis patients.

Pharmacokinetics, safety and efficacy of an allometric miltefosine regimen for the treatment of visceral leishmaniasis in Eastern African children: an open-label, phase-II clinical trial

Please, let notWestern quackery replace traditional medicine inAfrica ⬇️

Population Pharmacokinetics of Fludarabine in Children and Adults during Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation

Population pharmacokinetics of artemether, dihydroartemisinin and lumefantrine in Rwandese pregnant women treated for uncomplicated malaria

Population pharmacokinetics of levamisole in children with steroid-sensitive nephrotic syndrome

Predictable threats to public health through delaying universal access to innovative medicines for hepatitis C: a pharmaceutical standpoint

Quantification of miltefosine in peripheral blood mononuclear cells by high-performance liquid chromatography-tandem mass spectrometry

Reply to Arya and Agarwal

Safe mass drug administration for neglected tropical diseases

Safety and efficacy of miltefosine alone and in combination with sodium stibogluconate and liposomal amphotericin B for the treatment of primary visceral leishmaniasis in East Africa: study protocol for a randomized controlled trial.

Safety and efficacy of single dose versus multiple doses of AmBisome for treatment of visceral leishmaniasis in eastern Africa: a randomised trial

Severe encephalopathy and polyneuropathy induced by dichloroacetate.

Simultaneous population pharmacokinetic modelling of plasma and intracellular PBMC miltefosine concentrations in New World cutaneous leishmaniasis and exploration of exposure-response relationships

Systematic Review of Host-Mediated Activity of Miltefosine in Leishmaniasis through Immunomodulation.

Systematic review of biomarkers to monitor therapeutic response in leishmaniasis

The global impact of Indian generics on access to health ⬇️

Translational pharmacokinetic modelling and simulation for the assessment of duration of contraceptive use after treatment with miltefosine.

Treatment of visceral leishmaniasis: pitfalls and stewardship

Universal access to quality medicines: prioritisation of a-priori solutions

Validation and Clinical Evaluation of a Novel Method To Measure Miltefosine in Leishmaniasis Patients Using Dried Blood Spot Sample Collection.

Visceral leishmaniasis relapse hazard is linked to reduced miltefosine exposure in patients from Eastern Africa: a population pharmacokinetic/pharmacodynamic study.

Volumetric absorptive microsampling (VAMS) as an alternative to conventional dried blood spots in the quantification of miltefosine in dried blood samples.