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List of works by Sean P Troth

A rapid urine test for early detection of kidney injury.

scientific article published on 22 April 2009

Clinical development of a recombinant Ebola vaccine in the midst of an unprecedented epidemic

scientific article

Evaluation of 10 Urinary Biomarkers for Renal Safety With 5 Nephrotoxicants in Nonhuman Primates

scientific article published on 01 July 2020

Evaluation of the relative performance of 12 urinary biomarkers for renal safety across 22 rat sensitivity and specificity studies

scientific article published on 21 December 2013

Graphical display of histopathology data from toxicology studies for drug discovery and development: An industry perspective.

scientific article published on 18 October 2016

In vivo CXCR4 expression, lymphoid cell phenotype, and feline immunodeficiency virus infection.

scientific article published on 19 January 2008

Integrated pathway analysis of rat urine metabolic profiles and kidney transcriptomic profiles to elucidate the systems toxicology of model nephrotoxicants

scientific journal article

Kidney Safety Assessment: Current Practices in Drug Development

scientific article published on 01 March 2019

Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies.

scientific article

Performance Assessment of New Urinary Translational Safety Biomarkers of Drug-induced Renal Tubular Injury in Tenofovir-treated Cynomolgus Monkeys and Beagle Dogs

scientific article published on 28 May 2018

Rat Urinary Osteopontin and Neutrophil Gelatinase-Associated Lipocalin Improve Certainty of Detecting Drug-Induced Kidney Injury.

scientific article

Recommendations for the evaluation of pathology data in nonclinical safety biomarker qualification studies.

scientific article

Regulatory Forum Opinion Piece*: Imaging Applications in Toxicologic Pathology-Recommendations for Use in Regulated Nonclinical Toxicity Studies.

scientific article

Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium

article

Scientific and Regulatory Policy Committee Points to Consider*: Approaches to the Conduct and Interpretation of Vaccine Safety Studies for Clinical and Anatomic Pathologists

scientific article published on 08 October 2019

Scientific and Regulatory Policy Committee Points to Consider*: The Toxicologic Pathologist's Role in the 3Rs

scientific article published on 01 October 2019

Scientific and Regulatory Policy Committee Points to Consider: Data Visualization for Clinical and Anatomic Pathologists

scientific article published on 29 May 2018

Topic of histopathology blinding in nonclinical safety biomarker qualification studies

scientific article published on 01 June 2010

Towards consensus practices to qualify safety biomarkers for use in early drug development

article

Toxicologic Pathology Forum*: Commentary on "Opinion on Designation of Adverse and Nonadverse Histopathological Findings in Toxicity Studies: The Pathologist's Dilemma"

scientific article published on 14 July 2019

Translational Safety Biomarkers of Kidney Injury

scientific article published on 01 March 2019

rVSVΔG-ZEBOV-GP (also designated V920) recombinant vesicular stomatitis virus pseudotyped with Ebola Zaire Glycoprotein: Standardized template with key considerations for a risk/benefit assessment

scientific article published on 29 January 2019

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