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List of works by Nicole G H Leferink

3DM: systematic analysis of heterogeneous superfamily data to discover protein functionalities.

scientific article

A 'Plug and Play' Platform for the Production of Diverse Monoterpene Hydrocarbon Scaffolds in Escherichia coli.

scientific article published in June 2016

Aldonolactone oxidoreductases

scientific article published on January 2014

Correlating Calmodulin Landscapes with Chemical Catalysis in Neuronal Nitric Oxide Synthase using Time-Resolved FRET and a 5-Deazaflavin Thermodynamic Trap

scientific article

Experiment and Simulation Reveal How Mutations in Functional Plasticity Regions Guide Plant Monoterpene Synthase Product Outcome

article

Exploring novel bacterial terpene synthases

scientific article published on 30 April 2020

Functional assignment of Glu386 and Arg388 in the active site of L-galactono-gamma-lactone dehydrogenase.

scientific article published on 6 September 2009

Galactonolactone dehydrogenase requires a redox-sensitive thiol for optimal production of vitamin C.

scientific article published on 15 April 2009

Galactonolactone oxidoreductase from Trypanosoma cruzi employs a FAD cofactor for the synthesis of vitamin C

scientific article published on 21 March 2011

Gating mechanisms for biological electron transfer: integrating structure with biophysics reveals the nature of redox control in cytochrome P450 reductase and copper-dependent nitrite reductase.

scientific article published on 14 July 2011

Identification of a gatekeeper residue that prevents dehydrogenases from acting as oxidases.

scientific article

Impact of residues remote from the catalytic centre on enzyme catalysis of copper nitrite reductase

scientific article

Laboratory evolution of Pyrococcus furiosus alcohol dehydrogenase to improve the production of (2S,5S)-hexanediol at moderate temperatures.

scientific article

Laser-flash photolysis indicates that internal electron transfer is triggered by proton uptake by Alcaligenes xylosoxidans copper-dependent nitrite reductase.

scientific article

Occurrence and biocatalytic potential of carbohydrate oxidases.

scientific article published on January 2006

Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase.

scientific article published on 9 August 2017

Taming the Reactivity of Monoterpene Synthases To Guide Regioselective Product Hydroxylation

scientific article published on 03 December 2019

The growing VAO flavoprotein family.

scientific article published on 06 February 2008

Towards the free energy landscape for catalysis in mammalian nitric oxide synthases.

scientific article published on 09 December 2014