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List of works by Melissa M J Farnham

Activation of PAC(1) and VPAC receptor subtypes elicits differential physiological responses from sympathetic preganglionic neurons in the anaesthetized rat.

scientific article

Activation of µ-opioid receptors in the rostral ventrolateral medulla blocks the sympathetic counter-regulatory response to glucoprivation

scientific article published on 03 October 2018

Acute intermittent hypoxia with concurrent hypercapnia evokes P2X and TRPV1 receptor-dependent sensory long-term facilitation in naïve carotid bodies.

scientific article published on 21 November 2017

Alerted microglia and the sympathetic nervous system: A novel form of microglia in the development of hypertension

scientific article published on 28 November 2015

Antagonism of PACAP or microglia function worsens the cardiovascular consequences of kainic-acid-induced seizures in rats.

scientific article published in February 2015

Catestatin has an unexpected effect on the intrathecal actions of PACAP dramatically reducing blood pressure

scientific article published on 08 August 2012

DNA Damage-Sensing Kinases Mediate the Mouse 2-Cell Embryo's Response to Genotoxic Stress ⬇️

scientific article published on May 18, 2011

Dynamic changes in the relationship of microglia to cardiovascular neurons in response to increases and decreases in blood pressure.

scientific article published on 4 May 2016

Effects of baroreceptor activation on respiratory variability in rat.

scientific article published on 24 February 2009

Gene Interference with Morpholinos in a Gold Nanoparticle-Based Delivery Platform in Rat PC12 Cells.

scientific article published in December 2015

Glia and central cardiorespiratory pathology

scientific article published on 24 August 2018

Inhibition of microglial activation with minocycline at the intrathecal level attenuates sympathoexcitatory and proarrhythmogenic changes in rats with chronic temporal lobe epilepsy.

scientific article published on 16 March 2017

Integration of hindbrain and carotid body mechanisms that control the autonomic response to cardiorespiratory and glucoprivic insults

scientific article published on 30 August 2018

Intermittent hypoxia-induced cardiorespiratory long-term facilitation: A new role for microglia

scientific article published on 22 March 2016

Intrathecal Intermittent Orexin-A Causes Sympathetic Long-Term Facilitation and Sensitizes the Peripheral Chemoreceptor Response to Hypoxia in Rats

scientific article published on 06 July 2016

Intrathecal PACAP-38 causes increases in sympathetic nerve activity and heart rate but not blood pressure in the spontaneously hypertensive rat

scientific article published on 15 October 2010

Intrathecal PACAP-38 causes prolonged widespread sympathoexcitation via a spinally mediated mechanism and increases in basal metabolic rate in anesthetized rat

scientific article published on 01 April 2011

Metabotropic neurotransmission and integration of sympathetic nerve activity by the rostral ventrolateral medulla in the rat.

scientific article published on April 2008

Microglia PACAP and glutamate: Friends or foes in seizure-induced autonomic dysfunction and SUDEP?

scientific article

Microglia in the RVLM of SHR have reduced P2Y12R and CX3CR1 expression, shorter processes, and lower cell density

scientific article published on 08 December 2018

Microglial number is related to the number of tyrosine hydroxylase neurons in SHR and normotensive rats.

scientific article published on 24 May 2016

Optogenetics, the intersection between physics and neuroscience: light stimulation of neurons in physiological conditions

scientific article published on October 2014

PACAP causes PAC1/VPAC2 receptor mediated hypertension and sympathoexcitation in normal and hypertensive rats.

scientific article published on 10 August 2012

PACAP is expressed in sympathoexcitatory bulbospinal C1 neurons of the brain stem and increases sympathetic nerve activity in vivo.

scientific article

PACAP(6-38) or kynurenate microinjections into the RVLM prevent development of sympathetic long-term facilitation following acute intermittent hypoxia.

scientific article

Rostroventrolateral medulla neurons with commissural projections provide input to sympathetic premotor neurons: anatomical and functional evidence

article

Seizure-Induced Sympathoexcitation Is Caused by Activation of Glutamatergic Receptors in RVLM That Also Causes Proarrhythmogenic Changes Mediated by PACAP and Microglia in Rats.

scientific article published in January 2016

Surgical preparation of mice for recording cardiorespiratory parameters in vivo

scientific article published on 7 April 2015

The effect of losartan on differential reflex control of sympathetic nerve activity in chronic kidney disease

scientific article published on 01 June 2015

pSer40 tyrosine hydroxylase immunohistochemistry identifies the anatomical location of C1 neurons in rat RVLM that are activated by hypotension.

scientific article published on 11 January 2016

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