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List of works by Elena Scotti

Bile acids and gene regulation: from nuclear receptors to chromatin.

scientific article published on May 2008

Bile acids and their signaling pathways: eclectic regulators of diverse cellular functions.

scientific article published on October 2007

Both K63 and K48 ubiquitin linkages signal lysosomal degradation of the LDL receptor.

scientific article published on 18 February 2013

Chlamydia pneumoniae acute liver infection affects hepatic cholesterol and triglyceride metabolism in mice.

scientific article published on 03 June 2015

Comparative systems toxicology analysis of cigarette smoke and aerosol from a candidate modified risk tobacco product in organotypic human gingival epithelial cultures: A 3-day repeated exposure study.

scientific article published on 23 December 2016

Crystal structure of the peroxisome proliferator-activated receptor gamma (PPARgamma) ligand binding domain complexed with a novel partial agonist: a new region of the hydrophobic pocket could be exploited for drug design

scientific article

Insights in the regulation of cholesterol 7alpha-hydroxylase gene reveal a target for modulating bile acid synthesis.

scientific article

Site-directed mutagenesis to study the role of specific amino acids in the ligand binding domain of PPARs.

scientific article

Structural insight into peroxisome proliferator-activated receptor gamma binding of two ureidofibrate-like enantiomers by molecular dynamics, cofactor interaction analysis, and site-directed mutagenesis

scientific article published on June 2010

The LXR-Idol axis differentially regulates plasma LDL levels in primates and mice

scientific article

The pharmacological exploitation of cholesterol 7alpha-hydroxylase, the key enzyme in bile acid synthesis: from binding resins to chromatin remodelling to reduce plasma cholesterol.

scientific article published on 07 September 2007