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List of works by Yves A. Lussier

'N-of-1-pathways' unveils personal deregulated mechanisms from a single pair of RNA-Seq samples: towards precision medicine

scientific article

A "systematics" tool for medical terminologies

scientific article

A Sphingosine 1–Phosphate 1 Receptor Agonist Modulates Brain Death–Induced Neurogenic Pulmonary Injury ⬇️

scientific article published on May 26, 2011

A Web-based System For Prediction Of Coronary Heart Disease Risk Using The Framingham Algorithm

scientific article published in January 2000

A cloud-based approach to medical NLP

scientific article (publication date: 2011)

A functional genomic model for predicting prognosis in idiopathic pulmonary fibrosis.

scientific article published on 21 November 2015

A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbations

scientific article published on November 2017

A study of abbreviations in the UMLS.

scientific article

ARTS: automated randomization of multiple traits for study design

scientific article published on 3 February 2014

Accelerating precision biology and medicine with computational biology and bioinformatics

scientific article

Adapting current Arden Syntax knowledge for an object oriented event monitor.

scientific article

Advantages of genomic complexity: bioinformatics opportunities in microRNA cancer signatures.

scientific article published on 18 November 2011

An integrated genomic approach to the assessment and treatment of acute myeloid leukemia.

scientific article published on April 2011

An integrative genomic approach to uncover molecular mechanisms of prokaryotic traits

scientific article published on 17 November 2006

An integrative genomic approach to uncover molecular mechanisms of prokaryotic traits

scholarly article by Yang Liu published in January 2005

Analysis of aggregated cell-cell statistical distances within pathways unveils therapeutic-resistance mechanisms in circulating tumor cells

scientific article published on June 2016

Association of circulating transcriptomic profiles with mortality in sickle cell disease

scientific article

Automating ICD-9-CM Encoding Using Medical Language Processing: A Feasibility Study

Automating terminological networks to link heterogeneous biomedical databases

scientific article

Biomolecular Systems of Disease Buried Across Multiple GWAS Unveiled by Information Theory and Ontology.

scientific article published on March 2010

Breakthroughs in genomics data integration for predicting clinical outcome ⬇️

scientific article (publication date: December 2012)

COPD Hospitalization Risk Increased with Distinct Patterns of Multiple Systems Comorbidities Unveiled by Network Modeling

scientific article published on 14 November 2014

Cascading Policies Provide Fault Tolerance for Pervasive Clinical Communications

scientific article published on 01 March 2005

Challenges and remediation for Patient Safety Indicators in the transition to ICD-10-CM

scientific article

Chronic intestinal inflammation induces stress-response genes in commensal Escherichia coli.

scientific article published on 2 July 2011

Comparing SNOMED and ICPC retrieval accuracies using relational database models ⬇️

scientific article published on January 1, 1997

Complex genetics of pulmonary diseases: lessons from genome-wide association studies and next-generation sequencing

scientific article

Complex-disease networks of trait-associated single-nucleotide polymorphisms (SNPs) unveiled by information theory.

scientific article published on 25 January 2012

Comprehensive viral oligonucleotide probe design using conserved protein regions

scientific article (publication date: 2008)

Computational approaches to phenotyping: high-throughput phenomics.

scientific article published on January 2007

Concordance of deregulated mechanisms unveiled in underpowered experiments: PTBP1 knockdown case study

scientific article

Conquering computational challenges of omics data and post-ENCODE paradigms

scientific article published on 23 August 2013

Correction: Oligo- and Polymetastatic Progression in Lung Metastasis(es) Patients Is Associated with Specific MicroRNAs.

scientific article published on 7 June 2013

Current methodologies for translational bioinformatics

scientific article

Curvilinear associations between neuroticism and dyadic adjustment in treatment-seeking couples

scientific article published on 01 April 2013

Deregulation of a Hox protein regulatory network spanning prostate cancer initiation and progression

scientific article

Detection of practice pattern trends through Natural Language Processing of clinical narratives and biomedical literature

scientific article published on 11 October 2007

Developing a 'personalome' for precision medicine: emerging methods that compute interpretable effect sizes from single-subject transcriptomes

scientific article published on 18 December 2017

Developing and Evaluating Theory-based Educational Content for WEB Applications.

scientific article published in January 2000

Developing tailored theory-based educational content for WEB applications: illustrations from the MI-HEART project.

scientific article

Development and validation of a brief version of the dyadic adjustment scale with a nonparametric item analysis model

scientific article published in March 2005

Disambiguating ambiguous biomedical terms in biomedical narrative text: an unsupervised method

scientific article published in August 2001

Dynamic changes of RNA-sequencing expression for precision medicine: N-of-1-pathways Mahalanobis distance within pathways of single subjects predicts breast cancer survival

scientific article published on June 2015

Early exposure to violence, relationship violence, and relationship satisfaction in adolescents and emerging adults: The role of romantic attachment

scientific article published on 9 June 2016

Erratum: Wnt7a is a novel inducer of β-catenin-independent tumor-suppressive cellular senescence in lung cancer

scientific article published on 01 October 2015

Essential role of pre-B-cell colony enhancing factor in ventilator-induced lung injury

scientific article published on 24 July 2008

Evaluation of an Ontology-anchored Natural Language-based Approach for Asserting Multi-scale Biomolecular Networks for Systems Medicine

scientific article

Evaluation of high-throughput functional categorization of human disease genes

scientific article

Evidence Suggesting That Discontinuous Dosing of ALK Kinase Inhibitors May Prolong Control of ALK+ Tumors

scientific article published on 27 May 2015

Exploring SNOMED Using Phylogenetic Analysis Tools

scientific article published in January 2002

Exploring Wound-Healing Genomic Machinery with a Network-Based Approach.

scientific article published on 21 June 2017

Exprtarget: an integrative approach to predicting human microRNA targets

scientific article

Extended attributes of event monitor systems for criteria-based notification modalities.

scientific article

GO-Module: functional synthesis and improved interpretation of Gene Ontology patterns ⬇️

scientific article published on March 17, 2011

Genestrace: phenomic knowledge discovery via structured terminology.

scientific article

Genetic interactions between chromosomes 11 and 18 contribute to airway hyperresponsiveness in mice

scientific article

Genomic assessment of a multikinase inhibitor, sorafenib, in a rodent model of pulmonary hypertension

scientific article published on 26 February 2008

Guideline interaction: a study of interactions among drug-disease contraindication rules.

scientific article

Harnessing SNOMED: A Relational Database Design for the Computerized Patient Record (CPR).

scientific article

Harnessing Web Information Technologies for Secure, Adaptive and Individualized Health Communications

Identification of Jak-STAT signaling involvement in sarcoidosis severity via a novel microRNA-regulated peripheral blood mononuclear cell gene signature.

scientific article

Identification of common microRNA-mRNA regulatory biomodules in human epithelial cancers.

scientific article

Identifying clinically disruptive International Classification of Diseases 10th Revision Clinical Modification conversions to mitigate financial costs using an online tool

scientific article published on 11 February 2014

Improving the Development of Composite Educational Guidelines Using Decomposition of Concept Lattices.

scientific article published in January 2000

In Silico cancer cell versus stroma cellularity index computed from species-specific human and mouse transcriptome of xenograft models: towards accurate stroma targeting therapy assessment.

scientific article

Information visualization techniques in bioinformatics during the postgenomic era ⬇️

scientific article published on November 1, 2004

Integrating Governance of Research Informatics and Health Care IT Across an Enterprise: Experiences from the Trenches

scientific article published on 18 March 2013

Integration of Neuroimaging and Microarray Datasets through Mapping and Model-Theoretic Semantic Decomposition of Unstructured Phenotypes

scientific article published on 01 March 2009

Integration of Neuroimaging and Microarray Datasets through Mapping and Model-Theoretic Semantic Decomposition of Unstructured Phenotypes.

scientific article

Integration of curated databases to identify genotype-phenotype associations

scientific article published on 12 October 2006

Integrative genomics analyses unveil downstream biological effectors of disease-specific polymorphisms buried in intergenic regions

scientific article published on 27 April 2016

Interpreting personal transcriptomes: personalized mechanism-scale profiling of RNA-seq data

scientific article

Kinase inhibition-related adverse events predicted from in vitro kinome and clinical trial data

scientific article

Lessons Learned in the Early Phase of the MI-HEART Clinical Trial.

scientific article published in January 2001

Linking biomedical language information and knowledge resources: GO and UMLS.

scientific article

MAP17 Is a Necessary Activator of Renal Na+/Glucose Cotransporter SGLT2.

scientific article

MI-HEART: a Comprehensive Management System to Deliver, Monitor and Measure Efficacy of Individualized Web-based Education.

scientific article published in January 2001

Measuring the Accuracy of a Nomenclature Encoder Supporting Postcoordination

scientific article published in January 1998

Mechanism-anchored profiling derived from epigenetic networks predicts outcome in acute lymphoblastic leukemia

scientific article published on 17 September 2009

Metrics and tools for consistent cohort discovery and financial analyses post-transition to ICD-10-CM

scientific article published on 12 February 2015

MicroRNA expression characterizes oligometastasis(es)

scientific article (publication date: 2011)

Microbes Are Associated with Host Innate Immune Response in Idiopathic Pulmonary Fibrosis

scientific article published in July 2017

Mining OMIM for insight into complex diseases.

scientific article published on January 2004

Modeling patient response to acute myocardial infarction: implications for a tailored technology-based program to reduce patient delay

scientific article published on January 1999

Monitoring the function and use of a clinical decision support system

scientific article published on 11 October 2007

Murine lung responses to ambient particulate matter: genomic analysis and influence on airway hyperresponsiveness.

journal article published in 2008

N-of-1-pathways MixEnrich: advancing precision medicine via single-subject analysis in discovering dynamic changes of transcriptomes

scientific article

Natural language processing and visualization in the molecular imaging domain

scientific article published on 26 September 2006

Network modeling identifies molecular functions targeted by miR-204 to suppress head and neck tumor metastasis

scientific article

Network models of genome-wide association studies uncover the topological centrality of protein interactions in complex diseases

scientific article (publication date: 2013)

New autosomal recessive mutations in aquaporin-2 causing nephrogenic diabetes insipidus through deficient targeting display normal expression in Xenopus oocytes.

scientific article published on 19 April 2010

Non-muscle myosin light chain kinase isoform is a viable molecular target in acute inflammatory lung injury.

scientific article

Oligo- and polymetastatic progression in lung metastasis(es) patients is associated with specific microRNAs

scientific article

Overcoming the Barriers of Web-Based Interventions for Elder Patients: Enabling Strategies for the MI HEART Clinical Trial

scientific article published in January 1999

Panmicrobial Oligonucleotide Array for Diagnosis of Infectious Diseases

scientific article (publication date: 2007)

Particulate matter induces cardiac arrhythmias via dysregulation of carotid body sensitivity and cardiac sodium channels.

journal article published in 2012

Partitioning knowledge bases between advanced notification and clinical decision support systems

scientific article published on January 2005

People, organizational, and leadership factors impacting informatics support for clinical and translational research.

scientific article

Peripheral blood mononuclear cell gene expression profiles predict poor outcome in idiopathic pulmonary fibrosis

scientific article published on October 2013

PhenoGO: an integrated resource for the multiscale mining of clinical and biological data

scientific article

PhenoGO: assigning phenotypic context to gene ontology annotations with natural language processing.

scientific article

Prognostic implication of pulmonary function at the beginning of postoperative radiotherapy in non-small cell lung cancer

scientific article published on 28 November 2014

Protein interaction network underpins concordant prognosis among heterogeneous breast cancer signatures

scientific article

Protein-network modeling of prostate cancer gene signatures reveals essential pathways in disease recurrence.

scientific article

Putting data integration into practice: using biomedical terminologies to add structure to existing data sources

scientific article

Replication analysis for severe diabetic retinopathy

scientific article

Rethinking the role and impact of health information technology: informatics as an interventional discipline

scientific article

Robust informatics methods for accurate diagnosis using highly multiplexed virus arrays

scientific article published on 11 October 2007

Robust methods for accurate diagnosis using pan-microbiological oligonucleotide microarrays

scientific article

Role of FAM18B in diabetic retinopathy

scientific article

Role of sphingolipids in murine radiation‐induced lung injury: protection by sphingosine 1‐phosphate analogs ⬇️

scientific article published on June 28, 2011

Selected proceedings of the 2009 Summit on Translational Bioinformatics

scientific article published on 17 September 2009

Selected proceedings of the First Summit on Translational Bioinformatics 2008.

scientific article

Semantic Modeling for Exposomics with Exploratory Evaluation in Clinical Context.

scientific article published on 30 August 2017

Semantic webs for life sciences

scientific article

Simulation of ICD-9 to ICD-10-CM Transition for Family Medicine: Simple or Convoluted?

scientific article

Simvastatin attenuates radiation-induced murine lung injury and dysregulated lung gene expression.

scientific article

Single sample expression-anchored mechanisms predict survival in head and neck cancer

scientific article

Stimulating effect of external Myo-inositol on the expression of mutant forms of aquaporin 2.

scientific article published on July 2010

Terminology model discovery using natural language processing and visualization techniques

scientific article published on December 2006

Testing for differentially expressed genetic pathways with single-subject N-of-1 data in the presence of inter-gene correlation.

scientific article

The MI-HEART Project: Information Technology (IT) for One-to-One Tailored Patient Communication

scientific article published in January 2001

The SNOMED model: a knowledge source for the controlled terminology of the computerized patient record

scientific article published on June 1, 1998

The TEAM evaluation approach to Project FAMUS, a pan-Canadian risk register for primary care

scientific article published in January 1992

The complexity and challenges of the International Classification of Diseases, Ninth Revision, Clinical Modification to International Classification of Diseases, 10th Revision, Clinical Modification transition in EDs

scientific article published on 7 March 2015

The discriminatory cost of ICD-10-CM transition between clinical specialties: metrics, case study, and mitigating tools

scientific article

The emergence of genome-based drug repositioning

scientific article

The mitochondrial cardiolipin remodeling enzyme lysocardiolipin acyltransferase is a novel target in pulmonary fibrosis

scientific article

The rise of translational bioinformatics

scientific article published on 31 August 2012

The transition to ICD-10-CM: challenges for pediatric practice

scientific article published on 2 June 2014

Topological analysis of large-scale biomedical terminology structures.

scientific article published on 21 August 2007

Towards a PBMC "virogram assay" for precision medicine: Concordance between ex vivo and in vivo viral infection transcriptomes

scientific article published on 19 March 2015

Towards mechanism classifiers: expression-anchored Gene Ontology signature predicts clinical outcome in lung adenocarcinoma patients ⬇️

scientific article published on November 3, 2012

Translating Mendelian and complex inheritance of Alzheimer's disease genes for predicting unique personal genome variants ⬇️

scientific article published on March 1, 2012

Translational bioinformatics: linking knowledge across biological and clinical realms

scientific article

Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML.

scientific article published on 17 January 2012

Variants affecting exon skipping contribute to complex traits.

scientific article

Web-based tailoring and its effect on self-efficacy: results from the MI-HEART randomized controlled trial.

scientific article

Wnt7a is a novel inducer of β-catenin-independent tumor-suppressive cellular senescence in lung cancer

scientific article

binomialRF: interpretable combinatoric efficiency of random forests to identify biomarker interactions

scientific article published on 28 August 2020

eQTL networks unveil enriched mRNA master integrators downstream of complex disease-associated SNPs.

scientific article published on 30 October 2015

iDEG: A single-subject method for assessing gene differential expression from two transcriptomes of an individual

article

kMEn: Analyzing noisy and bidirectional transcriptional pathway responses in single subjects

scientific article published on 19 December 2016

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