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List of works by Cláudio Viegas-Junior

3-Hydroxy-piperidinyl-N-benzyl-acyl-arylhydrazone derivatives reduce neuropathic pain and increase thermal threshold mediated by opioid system

scientific article published on 20 February 2018

A Comparative Evaluation of Acetylcholinesterase Inhibition by AChE-ICER and in vitro Ellman's Modified Method of Simplified Analogs 3-O-Acetyl-N-Benzyl-Piperidine of Donepezil

scientific article published in 2015

Alkaloids derived from flowers of Senna spectabilis, (-)-cassine and (-)-spectaline, have antiproliferative activity on HepG2 cells for inducing cell cycle arrest in G1/S transition through ERK inactivation and downregulation of cyclin D1 expression

scientific article published on 23 November 2015

Alzheimer's Disease: Related Targets, Synthesis of Available Drugs, Bioactive Compounds Under Development, and Promising Results Obtained from Multi-target Approaches

scientific article published on 19 August 2020

Antinociceptive Profile of (-)-Spectaline: A Piperidine Alkaloid fromCassia leptophylla ⬇️

scientific article published on September 1, 2003

Benzophenone derivatives as cysteine protease inhibitors and biological activity against Leishmania(L.) amazonensis amastigotes

scientific article published on 20 September 2015

Biological and Chemical Aspects of Natural Biflavonoids from Plants: A Brief Review

scientific article

Cinnamoyl-N-Acylhydrazone-Donepezil Hybrids: Synthesis and Evaluation of Novel Multifunctional Ligands Against Neurodegenerative Diseases

scientific article published on 20 October 2020

Curcumin, Resveratrol and Cannabidiol as natural key-prototypes in drug design for neuroprotective agents

scientific article

Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer's Disease

scientific article published on 10 July 2020

Design, synthesis and evaluation of novel feruloyl-donepezil hybrids as potential multitarget drugs for the treatment of Alzheimer's disease.

scientific article published on 21 February 2017

Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates.

scientific article published on 31 January 2018

Donepezil: an important prototype to the design of new drug candidates for Alzheimer's disease

scientific article

Editorial: Oxidative Stress: How Has It Been Considered in the Design of New Drug Candidates for Neurodegenerative Diseases?

scientific article published on 09 December 2020

Further bioactive piperidine alkaloids from the flowers and green fruits of Cassia spectabilis

scientific article

In vitro evaluation of the schistosomicidal effect of the extracts, fractions and major 3-hydroxy-2,6-dialkyl-substituted piperidine alkaloids from the flowers of Senna spectabilis (Fabaceae)

scholarly article by Andreísa Teixeira de Castro published in September 2016

Leishmanicidal activity of the crude extract, fractions and major piperidine alkaloids from the flowers of Senna spectabilis

scientific article published in November 2013

Leishmanicidal, antiproteolytic and antioxidant evaluation of natural biflavonoids isolated from Garcinia brasiliensis and their semisynthetic derivatives

scientific article published on 28 June 2012

Molecular Hybridization as a Tool in the Design of Multi-Target Directed Drug Candidates for Neurodegenerative Diseases

scientific article published on 21 October 2019

Molecular hybridization: a useful tool in the design of new drug prototypes

scientific article published on January 2007

Multi-Target Directed Drugs: A Modern Approach for Design of New Drugs for the treatment of Alzheimer's Disease

scientific article published on May 2014

New multifunctional AChE inhibitor drug prototypes protect against Aβ-induced memory deficit

scientific article published on 11 September 2019

PQM130, a Novel Feruloyl-Donepezil Hybrid Compound, Effectively Ameliorates the Cognitive Impairments and Pathology in a Mouse Model of Alzheimer's Disease

scientific article published on 12 June 2019

Plant derived alkaloid (−)-cassine induces anti-inflammatory and anti-hyperalgesics effects in both acute and chronic inflammatory and neuropathic pain models

article

Potential Impact of the Multi-Target Drug Approach in the Treatment of Some Complex Diseases

scientific article published on 11 August 2020

Promising synergistic activity of fluconazole with bioactive Guttiferone-A and derivatives against non-albicans Candida species

scientific article published on 10 August 2018

Semisynthesis and antimicrobial activity of novel guttiferone-A derivatives

scientific article published on 18 February 2012

Synthesis and biological evaluation of novel piperidine-benzodioxole derivatives designed as potential leishmanicidal drug candidates.

scientific article

Synthetic resveratrol-curcumin hybrid derivative inhibits mitosis progression in estrogen positive MCF-7 breast cancer cells.

scientific article published in March 2018

Testing the methodology for dosimetry audit of heterogeneity corrections and small MLC-shaped fields: Results of IAEA multi-center studies

scientific article published on 03 March 2016

The Keap1/Nrf2-ARE Pathway as a Pharmacological Target for Chalcones

scientific article published on 20 July 2018

The Role of Natural Products in the Discovery of New Drug Candidates for the Treatment of Neurodegenerative Disorders II: Alzheimers Disease ⬇️

scientific article published on March 1, 2011

The role of natural products in the discovery of new drug candidates for the treatment of neurodegenerative disorders I: Parkinson's disease

scientific article published on March 2011

Thermoluminescent chip detector for in vivo dosimetry in pelvis and head & neck cancer treatment

scientific article

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