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Authors whose works are in public domain in at least one jurisdiction

List of works by Francesca Lavatelli

A Caenorhabditis elegans-based assay recognizes immunoglobulin light chains causing heart amyloidosis

scientific article

A novel approach for the purification and proteomic analysis of pathogenic immunoglobulin free light chains from serum.

scientific article published on 4 January 2011

A phase II trial of cyclophosphamide, lenalidomide and dexamethasone in previously treated patients with AL amyloidosis.

scientific article published on 14 September 2012

A practical approach to the diagnosis of systemic amyloidoses.

scientific article published on 30 January 2015

A strategy for synthesis of pathogenic human immunoglobulin free light chains in E. coli

scientific article

A workflow management system for the biological samples exchange within the amyloidosis network

scientific article published on June 1, 2011

AMICA: an electronic patient record specifically designed for an amyloidosis network

scientific article published on June 1, 2011

ATR-FTIR Spectroscopy Supported by Multivariate Analysis for the Characterization of Adipose Tissue Aspirates from Patients Affected by Systemic Amyloidosis

scientific article published on 04 February 2019

Advances in proteomic study of cardiac amyloidosis: progress and potential.

scientific article published on 28 September 2016

Amyloid fibrils containing fragmented ATTR may be the standard fibril composition in ATTR amyloidosis.

scientific article

Amyloidogenic and associated proteins in systemic amyloidosis proteome of adipose tissue.

scientific article

Biochemical markers in early diagnosis and management of systemic amyloidoses.

scientific article

Changes in tissue proteome associated with ATTR amyloidosis: insights into pathogenesis.

scientific article published on 2 May 2012

Circulating amyloidogenic free light chains and serum N-terminal natriuretic peptide type B decrease simultaneously in association with improvement of survival in AL.

scientific article published on 24 January 2006

Circulating free light chain measurement in the diagnosis, prognostic assessment and evaluation of response of AL amyloidosis: comparison of Freelite and N latex FLC assays

scientific article published on 27 March 2017

Clinical proteomics for diagnosis and typing of systemic amyloidoses.

scientific article published on January 2013

Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity

scientific article published in December 2017

Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient

scientific article published on 20 March 2019

How do we improve treatments for patients with amyloidosis using proteomics?

scientific article published on 23 May 2017

Identification and quantification of urinary monoclonal proteins by capillary electrophoresis in AL amyloidosis.

scientific article published in March 2017

Identification of Amyloidogenic Light Chains Requires the Combination of Serum-Free Light Chain Assay with Immunofixation of Serum and Urine

scientific article published on 08 January 2009

In situ characterization of protein aggregates in human tissues affected by light chain amyloidosis: a FTIR microspectroscopy study.

scientific article published on 04 July 2016

Malnutrition at diagnosis predicts mortality in patients with systemic immunoglobulin light-chain amyloidosis independently of cardiac stage and response to treatment.

scientific article published on 26 September 2013

Mass spectrometry-based proteomics as a diagnostic tool when immunoelectron microscopy fails in typing amyloid deposits

scientific article published on June 1, 2011

Melphalan and dexamethasone with or without bortezomib in newly diagnosed AL amyloidosis: a matched case–control study on 174 patients

scientific article published on 25 July 2014

Midregional proadrenomedullin (MR-proADM) is a powerful predictor of early death in AL amyloidosis

scientific article published on 09 November 2011

Modulating the cardiotoxic behaviour of immunoglobulin light chain dimers through point mutations

scientific article published on 01 January 2019

Novel mitochondrial protein interactors of immunoglobulin light chains causing heart amyloidosis.

scientific article published on 28 July 2015

Nutritional counseling improves quality of life and preserves body weight in systemic immunoglobulin light-chain (AL) amyloidosis.

scientific article published on 11 May 2015

Nutritional status independently affects quality of life of patients with systemic immunoglobulin light-chain (AL) amyloidosis.

scientific article published on 9 August 2011

Oral melphalan and dexamethasone grants extended survival with minimal toxicity in AL amyloidosis: long-term results of a risk-adapted approach.

scientific article

Patients with AL amyloidosis and low free light-chain burden have distinct clinical features and outcome.

scientific article

Patterns of relapse after upfront bortezomib therapy in AL amyloidosis

scientific article published on 01 March 2017

Prognostication of survival and progression to dialysis in AA amyloidosis

scientific article published on 01 March 2017

Proteomic characterization of amyloid deposits in transthyretin amyloidosis associated with various mutations

scientific article published on 01 June 2011

Proteomic typing of amyloid deposits in systemic amyloidoses.

scientific article published on December 2011

Proteomics in protein misfolding diseases.

scientific article published in January 2009

Proteomics with Mass Spectrometry Imaging: Beyond Amyloid Typing

scientific article published in February 2018

Proteotoxicity in cardiac amyloidosis: amyloidogenic light chains affect the levels of intracellular proteins in human heart cells

scientific article

Reliable typing of systemic amyloidoses through proteomic analysis of subcutaneous adipose tissue.

scientific article published on 13 September 2011

Salvage therapy with lenalidomide and dexamethasone in patients with advanced AL amyloidosis refractory to melphalan, bortezomib, and thalidomide

scientific article published on 30 April 2011

Severity and reversibility of cardiac dysfunction and residual concentration of amyloidogenic light chain predict overall survival of patients with AL amyloidosis who attain complete response

scientific article published on 01 March 2017

Shotgun protein profile of human adipose tissue and its changes in relation to systemic amyloidoses.

scientific article published on 21 October 2013

Simple, reliable detection of amyloid in fat aspirates using the fluorescent dye FSB: prospective study in 206 patients

scientific article published on 06 June 2019

Stanniocalcin1 is a key mediator of amyloidogenic light chain induced cardiotoxicity

scientific article

Systemic amyloidoses and proteomics: The state of the art.

scientific article published on 23 February 2016

The combination of thalidomide and intermediate-dose dexamethasone is an effective but toxic treatment for patients with primary amyloidosis (AL).

scientific article published on 30 November 2004

The concurrency of several biophysical traits links immunoglobulin light chains with toxicity in AL amyloidosis

scientific article published on 01 January 2019

The impact of renal function on the clinical performance of FLC measurement in AL amyloidosis

scientific article published on 01 June 2016

Treatment of IgM-associated AL amyloidosis with the combination of rituximab, bortezomib, and dexamethasone.

scientific article published in February 2011

Treatment with oral melphalan plus dexamethasone produces long-term remissions in AL amyloidosis

scientific article published on 01 July 2007

Urinary albumin to creatinine ratio in diagnosis and risk stratification of renal AL amyloidosis

scientific article published on 01 March 2017

Zebrafish model of amyloid light chain cardiotoxicity: regeneration versus degeneration

scientific article published on 15 March 2019