List of works - Esther C Y Woon

5-Benzamidoisoquinolin-1-ones and 5-(ω-Carboxyalkyl)isoquinolin-1-ones as Isoform-Selective Inhibitors of Poly(ADP-ribose) Polymerase 2 (PARP-2) ⬇️

scientific article published on March 18, 2011

A fluorescent methylation-switchable probe for highly sensitive analysis of FTO -methyladenosine demethylase activity in cells

scientific article published on 07 August 2018

A methylation-switchable conformational probe for the sensitive and selective detection of RNA demethylase activity

scientific article published on 14 April 2016

A safe lithium mimetic for bipolar disorder

scientific article

A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor of N6-methyladenosine demethylase FTO.

scientific article

Doxorubicin-loaded cell-derived nanovesicles: an alternative targeted approach for anti-tumor therapy.

scientific article

Dual-action inhibitors of HIF prolyl hydroxylases that induce binding of a second iron ion.

scientific article

Dynamic combinatorial chemistry employing boronic acids/boronate esters leads to potent oxygenase inhibitors.

scientific article

Dynamic combinatorial mass spectrometry leads to inhibitors of a 2-oxoglutarate-dependent nucleic acid demethylase

scientific article

Exploration of the nicotinamide-binding site of the tankyrases, identifying 3-arylisoquinolin-1-ones as potent and selective inhibitors in vitro

scientific article

Hepatic FTO expression is increased in NASH and its silencing attenuates palmitic acid-induced lipotoxicity

scientific article published on 17 September 2016

Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds

scientific article

Micro cell vesicle technology (mCVT): a novel hybrid system of gene delivery for hard-to-transfect (HTT) cells

scientific article published on 28 August 2020

Multiprotein Dynamic Combinatorial Chemistry: A Strategy for the Simultaneous Discovery of Subfamily-Selective Inhibitors for Nucleic Acid Demethylases FTO and ALKBH3

article

N(6)-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5.

scientific article published on 9 May 2016

Observations on the Deprotection of Pinanediol and Pinacol Boronate Esters via Fluorinated Intermediates

scientific article published on 01 January 2010

One-pot tandem Hurtley-retro-Claisen-cyclisation reactions in the synthesis of 3-substituted analogues of 5-aminoisoquinolin-1-one (5-AIQ), a water-soluble inhibitor of PARPs.

scientific article published on 22 June 2013

Plant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone Demethylases

scientific article

Poly(ADP-ribose)polymerase inhibition - where now?

scientific article

Solid-phase synthesis of chlorofusin analogues

scientific article published on 09 June 2007

Synthesis and evaluation of 3-(dihydroxyboryl)benzoic acids as D,D-carboxypeptidase R39 inhibitors.

scientific article published in October 2009

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases

scientific article

List of works by Esther C Y Woon

5-Benzamidoisoquinolin-1-ones and 5-(ω-Carboxyalkyl)isoquinolin-1-ones as Isoform-Selective Inhibitors of Poly(ADP-ribose) Polymerase 2 (PARP-2) ⬇️

A fluorescent methylation-switchable probe for highly sensitive analysis of FTO -methyladenosine demethylase activity in cells

A methylation-switchable conformational probe for the sensitive and selective detection of RNA demethylase activity

A safe lithium mimetic for bipolar disorder

A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor of N6-methyladenosine demethylase FTO.

Doxorubicin-loaded cell-derived nanovesicles: an alternative targeted approach for anti-tumor therapy.

Dual-action inhibitors of HIF prolyl hydroxylases that induce binding of a second iron ion.

Dynamic combinatorial chemistry employing boronic acids/boronate esters leads to potent oxygenase inhibitors.

Dynamic combinatorial mass spectrometry leads to inhibitors of a 2-oxoglutarate-dependent nucleic acid demethylase

Exploration of the nicotinamide-binding site of the tankyrases, identifying 3-arylisoquinolin-1-ones as potent and selective inhibitors in vitro

Hepatic FTO expression is increased in NASH and its silencing attenuates palmitic acid-induced lipotoxicity

Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds

Micro cell vesicle technology (mCVT): a novel hybrid system of gene delivery for hard-to-transfect (HTT) cells

Multiprotein Dynamic Combinatorial Chemistry: A Strategy for the Simultaneous Discovery of Subfamily-Selective Inhibitors for Nucleic Acid Demethylases FTO and ALKBH3

N(6)-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5.

Observations on the Deprotection of Pinanediol and Pinacol Boronate Esters via Fluorinated Intermediates

One-pot tandem Hurtley-retro-Claisen-cyclisation reactions in the synthesis of 3-substituted analogues of 5-aminoisoquinolin-1-one (5-AIQ), a water-soluble inhibitor of PARPs.

Plant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone Demethylases

Poly(ADP-ribose)polymerase inhibition - where now?

Solid-phase synthesis of chlorofusin analogues

Synthesis and evaluation of 3-(dihydroxyboryl)benzoic acids as D,D-carboxypeptidase R39 inhibitors.

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases