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List of works by Dongxin Lin

A cis-eQTL genetic variant of the cancer-testis gene CCDC116 is associated with risk of multiple cancers.

scientific article published on 26 June 2017

A functional BRCA1 coding sequence genetic variant contributes to risk of esophageal squamous cell carcinoma.

scientific article published on 8 June 2013

A functional polymorphism (-1607 1G→2G) in the matrix metalloproteinase-1 promoter is associated with development and progression of lung cancer

scientific article published on 26 April 2011

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

scientific article published on 31 January 2013

A genome-wide association study identifies common variants influencing serum uric acid concentrations in a Chinese population

scientific article

A genome-wide gene-environment interaction analysis for tobacco smoke and lung cancer susceptibility.

scientific article

A genome-wide gene-gene interaction analysis identifies an epistatic gene pair for lung cancer susceptibility in Han Chinese.

scientific article published on 09 December 2013

A polymorphism in miR-1262 regulatory region confers the risk of lung cancer in Chinese population.

scientific article published on 16 May 2017

A single-nucleotide polymorphism in the 3'-UTR region of the adipocyte fatty acid binding protein 4 gene is associated with prognosis of triple-negative breast cancer

scientific article published on 04 March 2016

ATM polymorphisms are associated with risk of radiation-induced pneumonitis.

scientific article published on 18 February 2010

An estrogen receptor alpha suppressor, microRNA-22, is downregulated in estrogen receptor alpha-positive human breast cancer cell lines and clinical samples.

scientific article

Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

journal article published in 2015

Assessment of XPD Lys751Gln and XRCC1 T-77C polymorphisms in advanced non-small-cell lung cancer patients treated with platinum-based chemotherapy

scientific article published on 03 December 2010

Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population

scientific article

Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations

scientific article published on 26 December 2016

Association between IVF/ICSI treatment and preterm birth and major perinatal outcomes among dichorionic-diamnionic twin pregnancies: a seven-year retrospective cohort study

scientific article published on 31 August 2020

Association between genetic variations in tumor necrosis factor receptor genes and survival of patients with T-cell lymphoma.

scientific article published on 24 May 2012

Association of CD28 gene polymorphism with cervical cancer risk in a Chinese population

scientific article published on 16 September 2010

Association of GWAS-identified lung cancer susceptibility loci with survival length in patients with small-cell lung cancer treated with platinum-based chemotherapy

scientific article

Association of P53 and ATM polymorphisms with risk of radiation-induced pneumonitis in lung cancer patients treated with radiotherapy.

scientific article

Association of TGF-β1 and XPD polymorphisms with severe acute radiation-induced esophageal toxicity in locally advanced lung cancer patients treated with radiotherapy

scientific article published on 01 October 2010

Association of candidate genetic variations with gastric cardia adenocarcinoma in Chinese population: a multiple interaction analysis.

scientific article published on 10 December 2010

Associations of ATM Polymorphisms With Survival in Advanced Esophageal Squamous Cell Carcinoma Patients Receiving Radiation Therapy.

scientific article published on 7 May 2015

Associations of Genetic Variations in MicroRNA Seed Regions With Acute Adverse Events and Survival in Patients With Rectal Cancer Receiving Postoperative Chemoradiation Therapy

scientific article published on 21 December 2017

Associations of Genetic Variations in Mismatch Repair Genes MSH3 and PMS1 with Acute Adverse Events and Survival in Patients with Rectal Cancer Receiving Postoperative Chemoradiotherapy

scientific article published on 26 December 2018

BRCA1-Associated Protein Increases Invasiveness of Esophageal Squamous Cell Carcinoma.

scientific article published on 2 August 2017

Characterization of functional excision repair cross-complementation group 1 variants and their association with lung cancer risk and prognosis.

scientific article published in May 2008

Characterization of large structural genetic mosaicism in human autosome

journal article published in 2015

Circulating microRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis

scientific article published on 10 December 2010

Comparison of dimension reduction-based logistic regression models for case-control genome-wide association study: principal components analysis vs. partial least squares

scientific article published on 20 April 2015

Correlations between genetic variations of glutathione synthetase gene and the response to platinum-based chemotherapy and prognosis of small cell lung cancer patients

scientific article published on February 2017

Cyclooxygenase-2 Gly587Arg variant is associated with differential enzymatic activity and risk of esophageal squamous-cell carcinoma.

scientific article

Cyclooxygenase-2 genetic variants are associated with survival in unresectable locally advanced non-small cell lung cancer

scientific article published on 23 March 2010

Cytokine BAFF gene variation is associated with survival of patients with T-cell lymphomas.

scientific article published on 14 February 2012

Dissecting esophageal squamous-cell carcinoma ecosystem by single-cell transcriptomic analysis

scientific article published on 06 September 2021

Effect of rs2293347 Polymorphism in EGFR on the Clinical Efficacy of Gefitinib in Patients with Non-small Cell Lung Cancer ⬇️

scientific article published on August 1, 2011

Evidence of associations of APOBEC3B gene deletion with susceptibility to persistent HBV infection and hepatocellular carcinoma

scientific article published on 04 December 2012

Excessive miR-25-3p maturation via N-methyladenosine stimulated by cigarette smoke promotes pancreatic cancer progression

scientific article published on 23 April 2019

Exome-wide analyses identify low-frequency variant in CYP26B1 and additional coding variants associated with esophageal squamous cell carcinoma

scientific article

Exome-wide analysis identifies three low-frequency missense variants associated with pancreatic cancer risk in Chinese populations

scientific article published in Nature Communications

Exposure to airborne PM2.5 suppresses microRNA expression and deregulates target oncogenes that cause neoplastic transformation in NIH3T3 cells

scientific article published on 21 August 2015

Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome

journal article published in 2016

Functional FEN1 polymorphisms are associated with DNA damage levels and lung cancer risk.

scientific article

Functional evaluation of missense variations in the human MAD1L1 and MAD2L1 genes and their impact on susceptibility to lung cancer.

scientific article

Functional genetic variations in cytotoxic T-lymphocyte antigen 4 and susceptibility to multiple types of cancer.

scientific article published in September 2008

Functional regulatory variants of MCL1 contribute to enhanced promoter activity and reduced risk of lung cancer in nonsmokers: implications for context-dependent phenotype of an antiapoptotic and antiproliferative gene in solid tumor.

scientific article published in September 2011

Functional role of BTB and CNC Homology 1 gene in pancreatic cancer and its association with survival in patients treated with gemcitabine.

scientific article

Functional role of PLCE1 intronic insertion variant associated with susceptibility to esophageal squamous-cell carcinoma.

scientific article published on 2 November 2017

Functional variants in cell death pathway genes and risk of pancreatic cancer.

scientific article published in May 2008

Genetic polymorphism in chemokine CCL22 and susceptibility to Helicobacter pylori infection-related gastric carcinoma.

scientific article

Genetic polymorphisms in cytochrome P450 genes are associated with an increased risk of squamous cell carcinoma of the larynx and hypopharynx in a Chinese population.

scientific article

Genetic polymorphisms in cytotoxic T-lymphocyte antigen 4 and cancer: the dialectical nature of subtle human immune dysregulation.

scientific article published on 28 July 2009

Genetic variant in TP63 on locus 3q28 is associated with risk of lung adenocarcinoma among never-smoking females in Asia

scientific article published on 25 February 2012

Genetic variant repressing ADH1A expression confers susceptibility to esophageal squamous-cell carcinoma.

scientific article published on 14 December 2017

Genetic variants at 5p15 are associated with risk and early onset of gastric cancer in Chinese populations ⬇️

scientific article published on July 29, 2013

Genetic variants at 6p21.1 and 7p15.3 are associated with risk of multiple cancers in Han Chinese

scientific journal article

Genetic variants on chromosome 15q25 associated with lung cancer risk in Chinese populations

scientific article published on 02 June 2009

Genetic variation in DNA repair gene RAD52 is associated with the response to platinum-based chemotherapy in SCLC patients

scientific article published on July 2016

Genetic variation in an miRNA-1827 binding site in MYCL1 alters susceptibility to small-cell lung cancer.

scientific article

Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions ⬇️

scientific article published on September 9, 2012

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

scientific journal article

Genome-wide association study identifies new susceptibility loci for epithelial ovarian cancer in Han Chinese women.

scientific article

Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations ⬇️

scientific article published on June 5, 2011

Genome-wide association study identifies three susceptibility loci for laryngeal squamous cell carcinoma in the Chinese population

scientific article published on 07 September 2014

Genome-wide association study on serum alkaline phosphatase levels in a Chinese population.

scientific article

Genomic Analyses Reveal Mutational Signatures and Frequently Altered Genes in Esophageal Squamous Cell Carcinoma.

scientific article

Genomic Characterization of Esophageal Squamous Cell Carcinoma Reveals Critical Genes Underlying Tumorigenesis and Poor Prognosis

scientific article published on April 2016

Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations

scientific article

Genomic comparison of esophageal squamous cell carcinoma and its precursor lesions by multi-region whole-exome sequencing

scientific article published on 12 September 2017

Germline variation in the 3'-untranslated region of the POU2AF1 gene is associated with susceptibility to lymphoma.

scientific article published on 27 March 2017

Identification of common variants in BRCA2 and MAP2K4 for susceptibility to sporadic pancreatic cancer.

scientific article published on 8 January 2013

Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations

scientific article published on 17 July 2019

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

journal article published in 2014

Imputation-based association analyses identify new lung cancer susceptibility variants in CDK6 and SH3RF1 and their interactions with smoking in Chinese populations ⬇️

scientific article published on May 3, 2013

Integrative analysis of gene expression profiles reveals specific signaling pathways associated with pancreatic duct adenocarcinoma

scientific article published on 27 April 2018

Interaction of P53 Arg72Pro and MDM2 T309G polymorphisms and their associations with risk of gastric cardia cancer

scientific article published on 17 July 2007

Interaction of cyclooxygenase-2 variants and smoking in pancreatic cancer: a possible role of nucleophosmin.

scientific article

Interactions between household air pollution and GWAS-identified lung cancer susceptibility markers in the Female Lung Cancer Consortium in Asia (FLCCA).

scientific article published on 8 January 2015

Long Noncoding RNA p53-Stabilizing and Activating RNA Promotes p53 Signaling by Inhibiting Heterogeneous Nuclear Ribonucleoprotein K deSUMOylation and Suppresses Hepatocellular Carcinoma

scientific article published on 12 August 2019

Low-frequency coding variants at 6p21.33 and 20q11.21 are associated with lung cancer risk in Chinese populations

scientific article

Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women

scientific article

Metabolome-wide association study identified the association between a circulating polyunsaturated fatty acids variant rs174548 and lung cancer

scientific article published in October 2017

Metformin inhibits pancreatic cancer metastasis caused by SMAD4 deficiency and consequent HNF4G upregulation

scientific article published on 31 July 2020

Metro system in Guangzhou as a hazardous reservoir of methicillin-resistant Staphylococci: findings from a point-prevalence molecular epidemiologic study.

scientific article published on 29 October 2015

Multi-loci analysis reveals the importance of genetic variations in sensitivity of platinum-based chemotherapy in non-small-cell lung cancer

scientific article published on 20 July 2012

Multi-omic characterization of genome-wide abnormal DNA methylation reveals diagnostic and prognostic markers for esophageal squamous-cell carcinoma

scientific article published on 25 February 2022

Neonatal colonization of group B Streptococcus in China: Prevalence, antimicrobial resistance, serotypes, and molecular characterization.

scientific article published on 3 January 2018

No association between XRCC1 polymorphisms and survival in non-small-cell lung cancer patients treated with platinum-based chemotherapy

scientific article published on 01 November 2010

OTUB1 promotes esophageal squamous cell carcinoma metastasis through modulating Snail stability.

scientific article published on 21 March 2018

PIWI-interacting RNA-36712 restrains breast cancer progression and chemoresistance by interaction with SEPW1 pseudogene SEPW1P RNA

scientific article published on 12 January 2019

PIWI-interacting RNA-54265 is oncogenic and a potential therapeutic target in colorectal adenocarcinoma.

scientific article published on 6 October 2018

Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation

scientific article published on 23 May 2016

Pathway Analysis for Genome-Wide Association Study of Lung Cancer in Han Chinese Population ⬇️

scientific article published on January 1, 2013

Phenotypic and molecular characterization of Streptococcus agalactiae colonized in Chinese pregnant women: predominance of ST19/III and ST17/III.

scientific article published on 26 January 2018

Polymorphisms of EGFR predict clinical outcome in advanced non-small-cell lung cancer patients treated with Gefitinib.

scientific article

Polymorphisms of death pathway genes FAS and FASL and risk of nasopharyngeal carcinoma

scientific article published on 01 November 2010

Polymorphisms of methylenetetrahydrofolate reductase are associated with a high risk of nasopharyngeal carcinoma in a smoking population from Southern China.

scientific article published on November 2010

Pulmonary expression of CYP2A13 and ABCB1 is regulated by FOXA2, and their genetic interaction is associated with lung cancer

scientific article

Relatively Small Contribution of Methylation and Genomic Copy Number Aberration to the Aberrant Expression of Inflammation-Related Genes in HBV-Related Hepatocellular Carcinoma.

scientific article published on 12 May 2015

Review and pooled analysis of studies on MTHFR C677T polymorphism and esophageal cancer.

scientific article

Risk of genome-wide association study-identified genetic variants for colorectal cancer in a Chinese population.

scientific article published on 8 June 2010

Risk of genome-wide association study-identified genetic variants for non-Hodgkin lymphoma in a Chinese population

scientific article published on 01 March 2013

Risk prediction of esophageal squamous-cell carcinoma with common genetic variants and lifestyle factors in Chinese population ⬇️

scientific article published on March 27, 2013

Role of velamentous cord insertion in monochorionic twin pregnancies: a PRISMA-compliant systematic review and meta-analysis of observational studies

scientific article published on 20 November 2018

Solute Carrier Family 39 Member 6 Gene Promotes Aggressiveness of Esophageal Carcinoma Cells by Increasing Intracellular Levels of Zinc, Activating Phosphatidylinositol 3-Kinase Signaling, and Up-regulating Genes That Regulate Metastasis.

scientific article published on 13 February 2017

Stability SCAD: a powerful approach to detect interactions in large-scale genomic study.

scientific article

Suppression of CYP2C9 by microRNA hsa-miR-128-3p in human liver cells and association with hepatocellular carcinoma.

scientific article

Systematical analyses of variants in CTCF-binding sites identified a novel lung cancer susceptibility locus among Chinese population

scientific article

Targeted sequencing of chromosome 15q25 identified novel variants associated with risk of lung cancer and smoking behavior in Chinese.

scientific article

The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia

scientific article

The Case‐Only Test for Gene–Environment Interaction is Not Uniformly Powerful: An Empirical Example ⬇️

scientific article published on March 13, 2013

The effect of gestational weight gain on perinatal outcomes among Chinese twin gestations based on Institute of Medicine guidelines

scientific article published on 24 July 2019

The effect of placental location identified before delivery on birthweight discordance among diamniotic-dichorionic twin pregnancies: a three-year retrospective cohort study

scientific article published on 20 August 2019

There is no association between microRNA gene polymorphisms and risk of triple negative breast cancer in a Chinese Han population.

scientific article

Trend and risk factors of low birth weight and macrosomia in south China, 2005-2017: a retrospective observational study.

scientific article published on 21 February 2018

Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women

scientific article published on 12 July 2019

Two genetic variants in prostate stem cell antigen and gastric cancer susceptibility in a Chinese population.

scientific article published in December 2009

Two novel variants on 13q22.1 are associated with risk of esophageal squamous cell carcinoma

scientific article published on 27 August 2015

Variations in HSPA1B at 6p21.3 are associated with lung cancer risk and prognosis in Chinese populations

scientific article published on 28 October 2011

Whole exome sequencing identifies lncRNA GAS8-AS1 and LPAR4 as novel papillary thyroid carcinoma driver alternations.

scientific article published on 2 March 2016

XRCC1 polymorphisms and severe toxicity in lung cancer patients treated with cisplatin-based chemotherapy in Chinese population

scientific article published on 09 April 2008

[Association between HLA-DQA1 gene copy number polymorphisms and susceptibility to gastric cancer]

scientific article published on 01 April 2012

[Genetic variation in DNA polymerase kappa gene is associated with the prognosis after platinum-based chemotherapy in small cell lung cancer patients]

scientific article published on 01 February 2019

[Genetic variations in MLH3 and MSH2 genes are associated with the sensitivity and prognosis in locally advanced rectal cancer patients receiving preoperative chemoradiotherapy]

scientific article published on 01 June 2018

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