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List of works by Thomas Lavstsen

A vaccine targeted specifically to prevent cerebral malaria - is there hope?

scholarly article by Lars Hviid et al published July 2018 in Expert Review of Vaccines

Acquisition of Antibodies Against Endothelial Protein C Receptor-Binding Domains of Plasmodium falciparum Erythrocyte Membrane Protein 1 in Children with Severe Malaria

scholarly article by Janavi S Rambhatla et al published 26 October 2018 in Journal of Infectious Diseases

Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria

scientific article published on 26 May 2016

An upstream open reading frame controls translation of var2csa, a gene implicated in placental malaria

scientific article

Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteers

scientific article

Cellulose filtration of blood from malaria patients for improving ex vivo growth of Plasmodium falciparum parasites

scientific article published on 10 February 2017

Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites

scientific article published on 12 June 2007

Corrigendum: Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors

scientific article published on 14 February 2018

Cytoadhesion to gC1qR through Plasmodium falciparum Erythrocyte Membrane Protein 1 in Severe Malaria

scientific article

DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families

scientific article

Differences in PfEMP1s recognized by antibodies from patients with uncomplicated or severe malaria

scientific article

Differential expression of var gene groups is associated with morbidity caused by Plasmodium falciparum infection in Tanzanian children

scientific article

Early gametocytes of the malaria parasite Plasmodium falciparum specifically remodel the adhesive properties of infected erythrocyte surface

scientific article published on 21 November 2012

Evidence for in vitro and in vivo expression of the conserved VAR3 (type 3) plasmodium falciparum erythrocyte membrane protein 1.

scientific article

Evidence for the involvement of VAR2CSA in pregnancy-associated malaria

scientific article

Expression of Plasmodium falciparum erythrocyte membrane protein 1 in experimentally infected humans

scientific article

Expression of a type B RIFIN in Plasmodium falciparum merozoites and gametes

scientific article published on 21 December 2012

Expression of the domain cassette 8 Plasmodium falciparum erythrocyte membrane protein 1 is associated with cerebral malaria in Benin

scientific article (publication date: 2013)

Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania

scientific article

Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children

scientific article

Identification of a major rif transcript common to gametocytes and sporozoites of Plasmodium falciparum

scientific article

IgG antibodies to endothelial protein C receptor-binding cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria

scientific article published on 26 May 2015

Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors

scientific article

Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria

scientific article published on 5 February 2007

Malaria's deadly grip: cytoadhesion of Plasmodium falciparum-infected erythrocytes

scientific article published on 04 September 2013

Multiple var2csa-type PfEMP1 genes located at different chromosomal loci occur in many Plasmodium falciparum isolates

scientific article

Parasites Causing Cerebral Falciparum Malaria Bind Multiple Endothelial Receptors and Express EPCR and ICAM-1-Binding PfEMP1.

scientific article

PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum

scientific article (publication date: 11 July 2013)

Plasmodium falciparum EPCR-binding PfEMP1 expression increases with malaria disease severity and is elevated in retinopathy negative cerebral malaria

scientific article published on 13 October 2017

Plasmodium falciparum Plasmodium helical interspersed subtelomeric proteins contribute to cytoadherence and anchor P. falciparum erythrocyte membrane protein 1 to the host cell cytoskeleton

scientific article (publication date: October 2016)

Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes

scientific article

Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquer

scientific article

Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children

scientific article

Plasmodium falciparum transcriptome analysis reveals pregnancy malaria associated gene expression

scientific article

Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domains

scientific article

Positive selection of Plasmodium falciparum parasites with multiple var2csa-type PfEMP1 genes during the course of infection in pregnant women

scientific article

Preferential transcription of conserved rif genes in two phenotypically distinct Plasmodium falciparum parasite lines

scientific article published on 30 December 2008

Programmed transcription of the var gene family, but not of stevor, in Plasmodium falciparum gametocytes

scientific article

Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria

scientific article (publication date: 30 May 2003)

Sequential, ordered acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 domains

scientific article published on 12 August 2009

Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites

scientific article (publication date: 2011)

Severe malaria is associated with parasite binding to endothelial protein C receptor

scientific article

Structural conservation despite huge sequence diversity allows EPCR binding by the PfEMP1 family implicated in severe childhood malaria

scientific article

Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria

scientific article published on March 2017

Sub-grouping of Plasmodium falciparum 3D7 var genes based on sequence analysis of coding and non-coding regions

scientific article

Surface co-expression of two different PfEMP1 antigens on single plasmodium falciparum-infected erythrocytes facilitates binding to ICAM1 and PECAM1

scientific article (publication date: 2010)

The Plasmodium falciparum var gene transcription strategy at the onset of blood stage infection in a human volunteer

scientific article published on 16 July 2009

The Severity of Plasmodium falciparum Infection Is Associated with Transcript Levels of var Genes Encoding Endothelial Protein C Receptor-Binding P. falciparum Erythrocyte Membrane Protein 1.

scientific article

The endothelial protein C receptor rs867186-GG genotype is associated with increased soluble EPCR and could mediate protection against severe malaria

scientific article published on 03 June 2016

The role of EPCR in the pathogenesis of severe malaria

scientific article

The structural basis for CD36 binding by the malaria parasite

scientific article

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