List of works by Narla Mohandas

"Baby" red cells to the rescue

scientific article published in September 2011

A 130-kDa protein 4.1B regulates cell adhesion, spreading, and migration of mouse embryo fibroblasts by influencing actin cytoskeleton organization

scientific article published on 31 December 2013

A Dynamic Spectrin-Dimer Self Association Regulates of Red cell MembraneMechanical Stability.

scientific article published in January 2001

A Golgi-associated protein 4.1B variant is required for assimilation of proteins in the membrane

scientific article published on 19 March 2009

A Maurer's cleft-associated protein is essential for expression of the major malaria virulence antigen on the surface of infected red blood cells

scientific article

A bacterial phosphatase-like enzyme of the malaria parasite Plasmodium falciparum possesses tyrosine phosphatase activity and is implicated in the regulation of band 3 dynamics during parasite invasion ⬇️

scientific article published on 3 July 2013

A band 3-based macrocomplex of integral and peripheral proteins in the RBC membrane

scientific article published on 16 January 2003

A dynamic alternative splicing program regulates gene expression during terminal erythropoiesis

scientific article published on 17 January 2014

A dynamic intron retention program enriched in RNA processing genes regulates gene expression during terminal erythropoiesis

scientific article published on 3 November 2015

A dynamic intron retention program in the mammalian megakaryocyte and erythrocyte lineages

scientific article published on 9 March 2016

A micro-bead device to explore Plasmodium falciparum-infected, spherocytic or aged red blood cells prone to mechanical retention by spleen endothelial slits.

scientific article

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

scientific article (publication date: 30 April 2015)

A transgenic mouse model demonstrates a dominant negative effect of a point mutation in the RPS19 gene associated with Diamond-Blackfan anemia

scientific article published on 6 July 2010

ATP-dependent Mechanism Protects Spectrin against Glycation in Human Erythrocytes* ⬇️

scientific article published on August 19, 2010

ATP11C is a major flippase in human erythrocytes and its defect causes congenital hemolytic anemia

scientific article published on 04 March 2016

Abnormal erythroid maturation leads to microcytic anemia in the TSAP6/Steap3 null mouse model

scientific article

Abnormal red cell features associated with hereditary neurodegenerative disorders: the neuroacanthocytosis syndromes

scientific article published on May 2014

Absolute proteome quantification of highly purified populations of circulating reticulocytes and mature erythrocytes

scientific article published on 01 October 2018

Adducin forms a bridge between the erythrocyte membrane and its cytoskeleton and regulates membrane cohesion

scientific article published on 30 June 2009

Adhesive activity of Lu glycoproteins is regulated by interaction with spectrin

scientific article published on 24 September 2008

Altered chromatin occupancy of master regulators underlies evolutionary divergence in the transcriptional landscape of erythroid differentiation

scientific article published on 18 December 2014

Altered phosphorylation of cytoskeleton proteins in sickle red blood cells: the role of protein kinase C, Rac GTPases, and reactive oxygen species

scientific article published on 15 March 2010

Alternative 5' exons and differential splicing regulate expression of protein 4.1R isoforms with distinct N-termini.

scientific article

An Unrecognized Function of Cholesterol: Regulating the Mechanism Controlling Membrane Phospholipid Asymmetry

scientific article published on 07 June 2016

An open-and-shut case?

scientific article published in October 2013

An update on the pathogenesis and diagnosis of Diamond-Blackfan anemia

Assignment of functional roles to parasite proteins in malaria-infected red blood cells by competitive flow-based adhesion assay

scientific article published on April 2002

Banking on red blood cells

scientific article published in January 2005

Blood group antigens in health and disease

scientific article

Canine elliptocytosis due to a mutant beta-spectrin

scientific article published on 28 October 2008

Case series supporting heme detoxification via therapeutic plasma exchange in acute multiorgan failure syndrome resistant to red blood cell exchange in sickle cell disease

scientific article published on 27 November 2017

Cellular adhesive phenomena in apicomplexan parasites of red blood cells

scientific article

Characterization of glycolytic enzyme interactions with murine erythrocyte membranes in wild-type and membrane protein knockout mice

scientific article

Characterization, regulation, and targeting of erythroid progenitors in normal and disordered human erythropoiesis

scientific article published on 17 January 2017

Cholesterol-binding protein TSPO2 coordinates maturation and proliferation of terminally differentiating erythroblasts

scientific article published on 01 May 2020

Circulating primitive erythroblasts establish a functional, protein 4.1R-dependent cytoskeletal network prior to enucleating

scientific article

Comparison of mechanisms of anemia in mice with sickle cell disease and beta-thalassemia: peripheral destruction, ineffective erythropoiesis, and phospholipid scramblase-mediated phosphatidylserine exposure

scientific article published in May 2002

Comprehensive Proteomic Analysis of Human Erythropoiesis

scientific article published on 20 July 2016

Comprehensive characterization of expression patterns of protein 4.1 family members in mouse adrenal gland: implications for functions

scientific article published on 2 October 2010

Comprehensive characterization of protein 4.1 expression in epithelium of large intestine

scientific article published on 10 June 2014

Conformational stabilities of the structural repeats of erythroid spectrin and their functional implications

scientific article published on 13 February 2006

Confounding in ex vivo models of Diamond-Blackfan anemia

scientific article published on 14 June 2017

Congenital erythropoietic porphyria: characterization of murine models of the severe common (C73R/C73R) and later-onset genotypes

scientific article

Contribution of parasite proteins to altered mechanical properties of malaria-infected red blood cells

scientific article published in February 2002

Control of erythrocyte membrane-skeletal cohesion by the spectrin-membrane linkage

scientific article

Cysteine shotgun-mass spectrometry (CS-MS) reveals dynamic sequence of protein structure changes within mutant and stressed cells

scientific article

Cytoplasmic remodeling of erythrocyte raft lipids during infection by the human malaria parasite Plasmodium falciparum

scientific article

Cytoskeletal protein 4.1R affects repolarization and regulates calcium handling in the heart

scientific article published on 11 September 2008

Cytoskeletal protein 4.1R negatively regulates T-cell activation by inhibiting the phosphorylation of LAT

scientific article published on 03 February 2009

Decreasing TfR1 expression reverses anemia and hepcidin suppression in β-thalassemic mice

scientific article

Deep intron elements mediate nested splicing events at consecutive AG dinucleotides to regulate alternative 3' splice site choice in vertebrate 4.1 genes

scientific article

Deletion of a malaria invasion gene reduces death and anemia, in model hosts ⬇️

scientific article (publication date: 2011)

Detection of detergent-resistant membranes in asexual blood-stage parasites of Plasmodium falciparum

scientific article published on 01 August 2003

Developmental differences between neonatal and adult human erythropoiesis

scientific article published on 23 December 2017

Diagnostic tool for red blood cell membrane disorders: Assessment of a new generation ektacytometer

scientific article published on 16 September 2015

Disorders of red cell membrane

scientific article

Dissecting the transcriptional phenotype of ribosomal protein deficiency: implications for Diamond-Blackfan Anemia

scientific article published on 15 May 2014

Distinct distribution of specific members of protein 4.1 gene family in the mouse nephron.

scientific article published in April 2003

Distinct roles for TET family proteins in regulating human erythropoiesis

scientific article published on 6 February 2017

Dusty protein kinases: primary structure, gene evolution, tissue specific expression and unique features of the catalytic domain

scientific article

Efficient in vivo manipulation of alternative pre-mRNA splicing events using antisense morpholinos in mice

scientific article

Erythroblastic islands, terminal erythroid differentiation and reticulocyte maturation

scientific article published on 05 February 2011

Erythroblastic islands: niches for erythropoiesis

scientific article published on August 2008

Erythrocyte G Protein-Coupled Receptor Signaling in Malarial Infection ⬇️

scientific article published on September 19, 2003

Erythrocyte G protein as a novel target for malarial chemotherapy

scientific article

Erythrocyte NADPH oxidase activity modulated by Rac GTPases, PKC, and plasma cytokines contributes to oxidative stress in sickle cell disease

scientific article published on 24 January 2013

Erythrocyte detergent-resistant membrane proteins: their characterization and selective uptake during malarial infection ⬇️

scientific article published on October 30, 2003

Erythrocyte membrane changes of chorea-acanthocytosis are the result of altered Lyn kinase activity

scientific article published on 27 September 2011

Erythrocyte remodeling by malaria parasites

scientific article published on May 2007

Evidence for a protective role of the Gardos channel against hemolysis in murine spherocytosis

scientific article published on 26 April 2005

Evolutionarily conserved coupling of transcription and alternative splicing in the EPB41 (protein 4.1R) and EPB41L3 (protein 4.1B) genes

scientific article published on 20 October 2005

Exome sequencing results in successful diagnosis and treatment of a severe congenital anemia

scientific article published on July 2016

First de novo mutation in RPS19 gene as the cause of hydrops fetalis in Diamond-Blackfan anemia

scientific article published in February 2013

First de novo mutation in RPS19 gene as the cause of hydrops fetalis in Diamond–Blackfan anemia

scientific article published in April 2013

Fluctuations of the red blood cell membrane: relation to mechanical properties and lack of ATP dependence

scientific article published on 30 January 2008

Function and dysfunction.

scientific article published in May 2018

Functional alteration of red blood cells by a megadalton protein of Plasmodium falciparum

scientific article (publication date: 22 January 2009)

Functional characterization of spectrin-actin-binding domains in 4.1 family of proteins

scientific article

Genetic variants in the noncoding region ofRPS19gene in Diamond-Blackfan anemia: Potential implications for phenotypic heterogeneity

article

Global transcriptome analyses of human and murine terminal erythroid differentiation

scientific article

Hereditary spherocytosis

scientific article

Hereditary spherocytosis and hereditary elliptocytosis: aberrant protein sorting during erythroblast enucleation

scientific article

Hereditary spherocytosis, elliptocytosis, and other red cell membrane disorders

scientific article published on 09 May 2013

High frequency of alternative first exons in erythroid genes suggests a critical role in regulating gene function

scientific article published on 17 November 2005

Human STEAP3 mutations with no phenotypic red cell changes

scientific article published on 16 December 2015

Human and murine erythropoiesis

scientific article

Hypoxia-induced acute lung injury in murine models of sickle cell disease

scientific article published on 12 September 2003

Identification and functional characterization of protein 4.1R and actin-binding sites in erythrocyte beta spectrin: regulation of the interactions by phosphatidylinositol-4,5-bisphosphate

scientific article

Identification of a functional role for lipid asymmetry in biological membranes: Phosphatidylserine-skeletal protein interactions modulate membrane stability

scientific article

Identification of a novel role for dematin in regulating red cell membrane function by modulating spectrin-actin interaction

scientific article

Identification of a third Protein 4.1 tumor suppressor, Protein 4.1R, in meningioma pathogenesis

scientific article (publication date: August 2003)

Identification of critical amino-acid residues on the erythroid intercellular adhesion molecule-4 (ICAM-4) mediating adhesion to alpha V integrins

scientific article published on 9 October 2003

Impaired intestinal calcium absorption in protein 4.1R-deficient mice due to altered expression of plasma membrane calcium ATPase 1b (PMCA1b).

scientific article published on 4 March 2013

Inactivation of Rb and E2f8 synergizes to trigger stressed DNA replication during erythroid terminal differentiation

scientific article

Integral protein linkage and the bilayer-skeletal separation energy in red blood cells

scientific article published on 4 April 2008

Inter-subunit interactions in erythroid and non-erythroid spectrins

scientific article

Interaction of Plasmodium falciparum knob-associated histidine-rich protein (KAHRP) with erythrocyte ankyrin R is required for its attachment to the erythrocyte membrane

scientific article

Interaction of the exported malaria protein Pf332 with the red blood cell membrane skeleton

scientific article

Interactions between Plasmodium falciparum skeleton-binding protein 1 and the membrane skeleton of malaria-infected red blood cells

scientific article (publication date: July 2015)

Interactions of Plasmodium falciparum erythrocyte membrane protein 3 with the red blood cell membrane skeleton

scientific article

Intrasplicing coordinates alternative first exons with alternative splicing in the protein 4.1R gene.

scientific article

Isolation and functional characterization of human erythroblasts at distinct stages: implications for understanding of normal and disordered erythropoiesis in vivo

scientific article published on 19 February 2013

Isolation and transcriptome analyses of human erythroid progenitors: BFU-E and CFU-E

scientific article

Jekyll and Hyde: the role of heme oxygenase-1 in erythroid biology

scientific article published on May 2015

KLF1 mutations are relatively more common in a thalassemia endemic region and ameliorate the severity of β-thalassemia

scientific article

Lack of protein 4.1G causes altered expression and localization of the cell adhesion molecule nectin-like 4 in testis and can cause male infertility

scientific article

Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells

scientific article

Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development

scientific article published on 04 February 2014

Lipid rafts and malaria parasite infection of erythrocytes

scientific article

Malaria Parasite Proteins and Their Role in Alteration of the Structure and Function of Red Blood Cells

scientific article published on 14 December 2015

Malaria and human red blood cells

scientific article

Malaria and the red blood cell membrane

scientific article published on April 2004

Malaria induces anemia through CD8+ T cell-dependent parasite clearance and erythrocyte removal in the spleen

scientific article

Malaria, erythrocytic infection, and anemia

scientific article

Mammalian alpha I-spectrin is a neofunctionalized polypeptide adapted to small highly deformable erythrocytes

scientific article

Mapping the domains of the cytoadherence ligand Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) that bind to the knob-associated histidine-rich protein (KAHRP)

scientific article published on 01 January 2002

Marked difference in membrane-protein-binding properties of the two isoforms of protein 4.1R expressed at early and late stages of erythroid differentiation

scientific article published in January 2009

Mature erythrocyte membrane homeostasis is compromised by loss of the GATA1-FOG1 interaction

scientific article

Mature parasite-infected erythrocyte surface antigen (MESA) of Plasmodium falciparum binds to the 30-kDa domain of protein 4.1 in malaria-infected red blood cells

scientific article published in May 2003

Measurements of red cell deformability and hydration reflect HbF and HbA2 in blood from patients with sickle cell anemia

scientific article published on 18 April 2017

Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry

scientific article published on 12 January 2018

Mechanism of protein sorting during erythroblast enucleation: role of cytoskeletal connectivity ⬇️

scientific article published on October 16, 2003

Membrane assembly during erythropoiesis

scientific article published on May 2011

Membrane peroxidation and methemoglobin formation are both necessary for band 3 clustering: mechanistic insights into human erythrocyte senescence

scientific article published on 16 August 2013

Membrane remodeling during reticulocyte maturation

scientific article

Merozoite surface proteins 4 and 5 of Plasmodium knowlesi have differing cellular localisation and association with lipid rafts

scientific article

Modulation of erythrocyte membrane mechanical function by protein 4.1 phosphorylation

scientific article published on 15 December 2004

More than one way to shrink

scientific article published in September 2015

Morphological and functional platelet abnormalities in Berkeley sickle cell mice

scientific article

Mutations in the murine erythroid alpha-spectrin gene alter spectrin mRNA and protein levels and spectrin incorporation into the red blood cell membrane skeleton

scientific article published on 08 August 2002

Native ultrastructure of the red cell cytoskeleton by cryo-electron tomography

scientific article

New insights into potential functions for the protein 4.1 superfamily of proteins in kidney epithelium

scientific article

No evidence for cell activation or brain vaso-occlusion with plerixafor mobilization in sickle cell mice

scientific article published on 21 December 2015

Novel secreted isoform of adhesion molecule ICAM-4: potential regulator of membrane-associated ICAM-4 interactions

scientific journal article

Nuclear substructure reorganization during late-stage erythropoiesis is selective and does not involve caspase cleavage of major nuclear substructural proteins

scientific article published on 2 June 2005

Nucleolar localization of RPS19 protein in normal cells and mislocalization due to mutations in the nucleolar localization signals in 2 Diamond-Blackfan anemia patients: potential insights into pathophysiology

scientific article

PEROXIREDOXIN-2: A NOVEL REGULATOR OF IRON HOMEOSTASIS IN INEFFECTIVE ERYTHROPOIESIS.

scientific article published on 10 August 2017

Peptides based on alphaV-binding domains of erythrocyte ICAM-4 inhibit sickle red cell-endothelial interactions and vaso-occlusion in the microcirculation

scientific article published on 31 May 2006

Phosphatidylinositol-4,5-biphosphate (PIP2) differentially regulates the interaction of human erythrocyte protein 4.1 (4.1R) with membrane proteins

scientific article

Phosphatidylserine binding sites in erythroid spectrin: location and implications for membrane stability

scientific article

Phosphatidylserine binding sites in red cell spectrin

scientific article published in May 2004

Phospholipid binding by proteins of the spectrin family: a comparative study

scientific article published in February 2005

Phosphorylation-dependent perturbations of the 4.1R-associated multiprotein complex of the erythrocyte membrane

scientific article

Piebaldism in diamond-blackfan anaemia: a new phenotype?

scientific article published on 01 November 2002

Plasmodium falciparum erythrocyte membrane protein 3 (PfEMP3) destabilizes erythrocyte membrane skeleton

scientific article (publication date: 14 September 2007)

Pomalidomide reverses γ-globin silencing through the transcriptional reprogramming of adult hematopoietic progenitors

scientific article published on 17 December 2015

Primary role for adherent leukocytes in sickle cell vascular occlusion: a new paradigm

scientific article

Procoagulant activity in patients with sickle cell trait

scientific article published in June 2012

Protein 4.1G Regulates Cell Adhesion, Spreading, and Migration of Mouse Embryonic Fibroblasts through the β1 Integrin Pathway

scientific article published on 7 December 2015

Protein 4.1N is required for the formation of the lateral membrane domain in human bronchial epithelial cells

scientific article published on 8 February 2018

Protein 4.1R links E-cadherin/beta-catenin complex to the cytoskeleton through its direct interaction with beta-catenin and modulates adherens junction integrity

scientific article published on 17 April 2009

Protein 4.1R regulates cell adhesion, spreading, migration and motility of mouse keratinocytes by modulating surface expression of beta1 integrin

scientific article

Protein 4.1R-dependent multiprotein complex: new insights into the structural organization of the red blood cell membrane

scholarly article

Protein and lipid trafficking induced in erythrocytes infected by malaria parasites

scientific article

Putative regulators for the continuum of erythroid differentiation revealed by single-cell transcriptome of human BM and UCB cells

scientific article published on 26 May 2020

Quantitative analysis of murine terminal erythroid differentiation in vivo: novel method to study normal and disordered erythropoiesis

scientific article published on 3 January 2013

Quantitative assessment of sensing and sequestration of spherocytic erythrocytes by the human spleen

scientific article

Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton

scientific article published in August 2006

Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c

scientific article

Red blood cell blood group antigens: structure and function

scientific article

Red cell indices in classification and treatment of anemias: from M.M. Wintrobes's original 1934 classification to the third millennium

scientific article published on May 2013

Red cell membrane: past, present, and future

scientific article

Regulation of globin-heme balance in Diamond-Blackfan anemia by HSP70/GATA1

scientific article published on 30 January 2019

Remodeling of the malaria parasite and host human red cell by vesicle amplification that induces artemisinin resistance

scientific article published on 23 January 2018

Resolving the distinct stages in erythroid differentiation based on dynamic changes in membrane protein expression during erythropoiesis

scientific article published on 28 September 2009

Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice

scientific article published on 23 August 2013

Ribosomal protein S19 expression during erythroid differentiation.

scientific article published on August 2002

Role of tissue-specific promoter DNA methylation in regulating the human EKLF gene

scientific article published on 15 February 2018

SF3B1 deficiency impairs human erythropoiesis via activation of p53 pathway: implications for understanding of ineffective erythropoiesis in MDS.

scientific article published on 12 February 2018

Sensing of red blood cells with decreased membrane deformability by the human spleen

scientific article published on 01 October 2018

Shear-response of the spectrin dimer-tetramer equilibrium in the red blood cell membrane.

scientific article published on 24 June 2002

Sickle red cell microrheology and sickle blood rheology

scientific article published in March 2004

Significant biochemical, biophysical and metabolic diversity in circulating human cord blood reticulocytes

scientific article (publication date: 2013)

Similarities and differences in the structure and function of 4.1G and 4.1R135, two protein 4.1 paralogues expressed in erythroid cells ⬇️

scientific article published on December 1, 2010

Stomatin and sensory neuron mechanotransduction.

scientific article published on 17 October 2007

Structural and functional studies of interaction between Plasmodium falciparum knob-associated histidine-rich protein (KAHRP) and erythrocyte spectrin

scientific article (publication date: 2 September 2005)

Study of the effects of proteasome inhibitors on ribosomal protein S19 (RPS19) mutants, identified in patients with Diamond-Blackfan anemia

scientific article

Surface area loss and increased sphericity account for the splenic entrapment of subpopulations of Plasmodium falciparum ring-infected erythrocytes

scientific article

Sustained treatment of sickle cell mice with haptoglobin increases HO-1 and H-ferritin expression and decreases iron deposition in the kidney without improvement in kidney function

scientific article published on 10 August 2016

Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice

scientific journal article

Targeted deletion of the gamma-adducin gene (Add3) in mice reveals differences in alpha-adducin interactions in erythroid and nonerythroid cells

scientific article

Targeted gene deletion demonstrates that the cell adhesion molecule ICAM-4 is critical for erythroblastic island formation

scientific article published on 11 May 2006

The 4.1B cytoskeletal protein regulates the domain organization and sheath thickness of myelinated axons

scientific article

The Interplay Between Peroxiredoxin-2 and Nuclear Factor-Erythroid 2 Is Important in Limiting Oxidative Mediated Dysfunction in β-Thalassemic Erythropoiesis

scientific article

The Laminin 511/521 binding site on the Lutheran blood group glycoprotein is located at the flexible junction of Ig domains 2 and 3

scientific article

The N-terminal 11 amino acids of human erythrocyte band 3 are critical for aldolase binding and protein phosphorylation: implications for band 3 function

scientific article published on 23 August 2005

The contribution of endothelial cell P-selectin to the microvascular flow of mouse sickle erythrocytes in vivo

scientific article published on 22 July 2004

The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments

scientific article

The erythroblastic island as an emerging paradigm in the anemia of inflammation

scientific article published on 16 September 2015

The erythroid niche: molecular processes occurring within erythroblastic islands

scientific article published on 23 July 2010

The human Kell blood group binds the erythroid 4.1R protein: new insights into the 4.1R-dependent red cell membrane complex

scientific article

The hydration state of human red blood cells and their susceptibility to invasion by Plasmodium falciparum ⬇️

scientific article published on 22 February 2005

The iron fist: malaria and hepcidin

scientific article

The ring-infected erythrocyte surface antigen (RESA) of Plasmodium falciparum stabilizes spectrin tetramers and suppresses further invasion ⬇️

scientific article (publication date: August 2007)

The road not taken?

scientific article

The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation

scientific article

The water channel aquaporin-1 partitions into exosomes during reticulocyte maturation: implication for the regulation of cell volume

scientific journal article

Thermal stabilities of brain spectrin and the constituent repeats of subunits

scientific article

To shrink or not to shrink

scientific article published in May 2013

Tropomyosin modulates erythrocyte membrane stability

scientific article published on 28 September 2006

Two distinct domains of protein 4.1 critical for assembly of functional nuclei in vitro

scientific article published on 8 August 2002

Two protein 4.1 domains essential for mitotic spindle and aster microtubule dynamics and organization in vitro

scientific article published on 21 April 2004

Unexpected role for p19INK4d in posttranscriptional regulation of GATA1 and modulation of human terminal erythropoiesis

scientific article published on 22 November 2016

Unraveling Macrophage Heterogeneity in Erythroblastic Islands

scientific article

miR-326 regulates HbF synthesis by targeting EKLF in human erythroid cells.

scientific article published on 27 March 2018

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