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List of works by Michael Lanzer

2-Acylamino-5-chlorobenzophenones with enhanced selectivity towards malaria parasites

scientific article published on 3 February 2011

3-D analysis of the Plasmodium falciparum Maurer's clefts using different electron tomographic approaches

scientific article

A HECT ubiquitin-protein ligase as a novel candidate gene for altered quinine and quinidine responses in Plasmodium falciparum

scientific article (publication date: May 2014)

A Redox-Active Fluorescent pH Indicator for Detecting Plasmodium falciparum Strains with Reduced Responsiveness to Quinoline Antimalarial Drugs

scientific article published on 7 December 2016

A conditional export system provides new insights into protein export in Plasmodium falciparum-infected erythrocytes

scientific article published on 5 August 2008

A global view of the nonprotein-coding transcriptome in Plasmodium falciparum

scientific article

A particle-based computational model to analyse remodelling of the red blood cell cytoskeleton during malaria infections

scientific article published on 08 April 2022

A putative Sec23 homologue of Plasmodium falciparum is located in Maurer's clefts

scientific article (publication date: July 2003)

A sequence element associated with thePlasmodium falciparumKAHRP gene is the site of developmentally regulated protein-DNA interactions ⬇️

scientific article published on June 25, 1992

A single member of the Plasmodium falciparum var multigene family determines cytoadhesion to the placental receptor chondroitin sulphate A.

scientific article

Analysis and screening of yeast artificial chromosome libraries by filter hybridization

scientific article

Antigenic variation in malaria: in situ switching, relaxed and mutually exclusive transcription of var genes during intra-erythrocytic development in Plasmodium falciparum ⬇️

scientific article published on September 15, 1998

Antimalarial and antitrypanosomal activity of a series of amide and sulfonamide derivatives of a 2,5-diaminobenzophenone

scientific article published on 25 September 2009

Antimalarial dual drugs based on potent inhibitors of glutathione reductase from Plasmodium falciparum

scientific article published on 9 February 2008

Antimalarial versus cytotoxic properties of dual drugs derived from 4-aminoquinolines and Mannich bases: interaction with DNA.

scientific article published on April 2010

Apparent bias for P. falciparum parasites carrying the wild-type pfcrt allele in the placenta

scientific article published on 11 February 2010

Association of Plasmodium falciparum isolates encoding the p. Falciparum chloroquine resistance transporter gene K76T polymorphism with anemia and splenomegaly, but not with multiple infections.

scientific article published on March 2005

Balancing drug resistance and growth rates via compensatory mutations in the Plasmodium falciparum chloroquine resistance transporter

scientific article published on 20 May 2015

CRIMALDDI: a co-ordinated, rational, and integrated effort to set logical priorities in anti-malarial drug discovery initiatives

scientific article

Changing ideas on chloroquine in Plasmodium falciparum

scientific article published on December 2000

Complementation of Saccharomyces cerevisiaepik1ts by a phosphatidylinositol 4-kinase from Plasmodium falciparum

scientific article (publication date: August 2010)

Computational and experimental analysis identified 6-diazo-5-oxonorleucine as a potential agent for treating infection by Plasmodium falciparum

scientific article published on 9 October 2013

Construction and screening of YAC libraries

scientific article

Construction of yeast artificial chromosome libraries from pathogens and nonmodel organisms

scientific article

Cytoadhesion of Plasmodium falciparum-infected erythrocytes to chondroitin-4-sulfate is cooperative and shear enhanced

scientific article

Declining malaria parasite prevalence and trends of asymptomatic parasitaemia in a seasonal transmission setting in North-Western Burkina Faso between 2000 and 2009-2012

scientific article published on 22 January 2013

Differences in trans-stimulated chloroquine efflux kinetics are linked to PfCRT in Plasmodium falciparum

scientific article published on April 2007

Differential Stimulation of the Na+/H+ Exchanger Determines Chloroquine Uptake in Plasmodium falciparum ⬇️

scientific article published on January 26, 1998

Differential time-dependent volumetric and surface area changes and delayed induction of new permeation pathways in P. falciparum-infected hemoglobinopathic erythrocytes

scientific article published on 23 July 2016

Direct activation of human endothelial cells by Plasmodium falciparum-infected erythrocytes

scientific article published on June 2005

Dissecting the components of quinine accumulation in Plasmodium falciparum

scientific article

Diverse mutational pathways converge on saturable chloroquine transport via the malaria parasite's chloroquine resistance transporter

scientific article

Drug-resistant malaria: molecular mechanisms and implications for public health

scientific article published on 23 April 2011

Erratum: SC83288 is a clinical development candidate for the treatment of severe malaria

scientific article published on 6 April 2017

Evaluation of the role of the endocytic receptor L-SIGN for cytoadhesion of Plasmodium falciparum-infected erythrocytes

scientific article published on 4 May 2005

Evidence for a pfcrt-associated chloroquine efflux system in the human malarial parasite Plasmodium falciparum

scientific article published on July 2005

Evidence for a substrate specific and inhibitable drug efflux system in chloroquine resistant Plasmodium falciparum strains

scientific article published on December 2004

Evidence for activation of endogenous transporters in Xenopus laevis oocytes expressing the Plasmodium falciparum chloroquine resistance transporter, PfCRT.

scientific article published on 16 July 2004

Evidence for trafficking of PfEMP1 to the surface of P. falciparum-infected erythrocytes via a complex membrane network

scientific article published in June 2003

Exploring the trifluoromenadione core as a template to design antimalarial redox-active agents interacting with glutathione reductase

scientific article published on 23 May 2012

Export of PfSBP1 to the Plasmodium falciparum Maurer's clefts

scientific article published on 20 November 2008

Export of virulence proteins by malaria-infected erythrocytes involves remodeling of host actin cytoskeleton

scientific article (publication date: 27 November 2014)

Functional expression of ribozymes in Apicomplexa: towards exogenous control of gene expression by inducible RNA-cleavage

scientific article published on 6 November 2007

Genetic linkage analyses redefine the roles of PfCRT and PfMDR1 in drug accumulation and susceptibility in Plasmodium falciparum

scientific article published on 18 October 2011

Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum

scientific article published on 22 June 2006

Genetic predisposition favors the acquisition of stable artemisinin resistance in malaria parasites

scientific article published on November 2010

Glutathione reductase-catalyzed cascade of redox reactions to bioactivate potent antimalarial 1,4-naphthoquinones--a new strategy to combat malarial parasites

scientific article (publication date: 3 August 2011)

Haemoglobin S and C affect the motion of Maurer's clefts in Plasmodium falciparum-infected erythrocytes

scientific article published on 20 January 2013

Hemoglobin S and C affect biomechanical membrane properties of P. falciparum-infected erythrocytes

scientific article published on 13 August 2019

Hemoglobin S and C affect protein export in Plasmodium falciparum-infected erythrocytes

scientific article published on 20 February 2015

Hemoglobins S and C interfere with actin remodeling in Plasmodium falciparum-infected erythrocytes

scientific article

Host actin remodeling and protection from malaria by hemoglobinopathies

scientific article published on 11 September 2012

Host cell factor CD59 restricts complement lysis of Plasmodium falciparum‐infected erythrocytes ⬇️

scientific article published on October 1, 1997

Illumination of the malaria parasite Plasmodium falciparum alters intracellular pH. Implications for live cell imaging

scientific article published on 24 July 2002

Immunization with full-length Plasmodium falciparum merozoite surface protein 1 is safe and elicits functional cytophilic antibodies in a randomized first-in-human trial

scientific article published on 31 January 2020

Iron is a substrate of the Plasmodium falciparum chloroquine resistance transporter PfCRT in Xenopus oocytes

scientific article

Is PfCRT a channel or a carrier? Two competing models explaining chloroquine resistance in Plasmodium falciparum

scientific article published on 10 May 2007

Is the Putative Chloroquine Resistance Mediator CG2 the Na+/H+ Exchanger of Plasmodium falciparum? ⬇️

scientific article published on March 6, 1998

Knockout of the peroxiredoxin 5 homologue PFAOP does not affect the artemisinin susceptibility of Plasmodium falciparum

scientific article

Lensless Tomographic Imaging of Near Surface Structures of Frozen Hydrated Malaria-Infected Human Erythrocytes by Coherent X-Ray Diffraction Microscopy

scientific article published on 26 October 2017

Malaria in a holoendemic area of Burkina Faso: a cross-sectional study

scientific article

Maternal malaria: Plasmodium falciparum sequestration in the placenta

scientific article

Maurer's clefts--a novel secretory organelle?

scientific article published on November 2003

Maurer's clefts: a novel multi-functional organelle in the cytoplasm of Plasmodium falciparum-infected erythrocytes

scientific article (publication date: 2006)

Modeling cytoadhesion of Plasmodium falciparum-infected erythrocytes and leukocytes-common principles and distinctive features

scientific article

Multiple drugs compete for transport via the Plasmodium falciparum chloroquine resistance transporter at distinct but interdependent sites

scientific article (publication date: 26 December 2014)

Nanofocused Scanning X-ray Fluorescence Microscopy Revealing an Effect of Heterozygous Hemoglobin S and C on Biochemical Activities in Plasmodium falciparum-Infected Erythrocytes

scientific article published on 31 March 2020

Novel type II fatty acid biosynthesis (FAS II) inhibitors as multistage antimalarial agents

scientific article published on 22 January 2013

Nuclear run-on analysis of var gene expression in Plasmodium falciparum

scientific article published on 22 February 2007

Overexpression of the HECT ubiquitin ligase PfUT prolongs the intraerythrocytic cycle and reduces invasion efficiency of Plasmodium falciparum. ⬇️

scientific article published on 4 December 2019

Oxidative insult can induce malaria-protective trait of sickle and fetal erythrocytes

scientific article

Parasitism and chromosome dynamics in protozoan parasites: is there a connection? ⬇️

scientific article published on March 1, 1995

PfCHA is a mitochondrial divalent cation/H+ antiporter in Plasmodium falciparum

scientific article (publication date: June 2010)

Pharmacomodulation of the Antimalarial Plasmodione: Synthesis of Biaryl- and N-Arylalkylamine Analogues, Antimalarial Activities and Physicochemical Properties

scientific article published on 19 January 2017

Phosphomimetic substitution at Ser-33 of the chloroquine resistance transporter PfCRT reconstitutes drug responses in Plasmodium falciparum

scientific article published on 08 July 2019

Plasmodium falciparum antioxidant protein as a model enzyme for a special class of glutaredoxin/glutathione-dependent peroxiredoxins

scientific article published on 24 April 2013

Plasmodium falciparum antioxidant protein reveals a novel mechanism for balancing turnover and inactivation of peroxiredoxins

scientific article

Polymorphisms within PfMDR1 alter the substrate specificity for anti-malarial drugs in Plasmodium falciparum

scientific article published on 18 August 2008

Profiling of the anti-malarial drug candidate SC83288 against artemisinins in Plasmodium falciparum

scientific article published on 20 March 2018

Prokaryotic ancestry and gene fusion of a dual localized peroxiredoxin in malaria parasites

scientific article (publication date: 5 January 2015)

Quantitative calcium measurements in subcellular compartments of Plasmodium falciparum-infected erythrocytes

scientific article published on 31 May 2005

Quantitative pH measurements in Plasmodium falciparum-infected erythrocytes using pHluorin

scientific article published on April 2007

Rational design of anticytoadherence inhibitors for Plasmodium falciparum based on the crystal structure of human intercellular adhesion molecule 1.

scientific article published in February 2006

Recovery of adhesion to chondroitin-4-sulphate in Plasmodium falciparum varCSA disruption mutants by antigenically similar PfEMP1 variants

scientific article

Rolling Adhesion of Schizont Stage Malaria-Infected Red Blood Cells in Shear Flow

scientific article published on May 2017

SC83288 is a clinical development candidate for the treatment of severe malaria.

scientific article published on 31 January 2017

Single-molecule imaging and quantification of the immune-variant adhesin VAR2CSA on knobs of -infected erythrocytes

scientific article published on 08 May 2019

Substantial increase in mutations in the genes pfdhfr and pfdhps puts sulphadoxine-pyrimethamine-based intermittent preventive treatment for malaria at risk in Burkina Faso

scientific article (publication date: June 2014)

Sulfonyl-phenyl-ureido benzamidines; a novel structural class of potent antimalarial agents

scientific article published in April 2004

Targeting a DBL3gamma domain of the Plasmodium falciparum erythrocyte membrane protein 1 to the surface of Saccharomyces cerevisiae.

scientific article published on 4 June 2004

The Plasmodium falciparum Maurer's clefts in 3D.

scientific article published on 19 December 2007

The Redox Cycler Plasmodione Is a Fast-Acting Antimalarial Lead Compound with Pronounced Activity against Sexual and Early Asexual Blood-Stage Parasites

scientific article

The antimalarial activities of methylene blue and the 1,4-naphthoquinone 3-[4-(trifluoromethyl)benzyl]-menadione are not due to inhibition of the mitochondrial electron transport chain

scientific article published on 25 February 2013

The histone H4 gene of Plasmodium falciparum is developmentally transcribed in asexual parasites

scientific article published on 9 May 2003

The sickle cell trait affects contact dynamics and endothelial cell activation in -infected erythrocytes

scientific article published on 30 November 2018

Ticket to ride: export of proteins to the Plasmodium falciparum-infected erythrocyte

scientific article published on 21 March 2016

Trafficking of STEVOR to the Maurer's clefts in Plasmodium falciparum-infected erythrocytes

scientific article

Trafficking of the exported P. falciparum chaperone PfHsp70x

scientific article (publication date: 8 November 2016)

Trafficking of the phosphoprotein PfCRT to the digestive vacuolar membrane in Plasmodium falciparum

scientific article (publication date: February 2010)

Trans stimulation provides evidence for a drug efflux carrier as the mechanism of chloroquine resistance in Plasmodium falciparum

scientific article published on August 2003

Transcription mapping of a 100 kb locus of Plasmodium falciparum identifies an intergenic region in which transcription terminates and reinitiates ⬇️

scientific article published on May 1, 1992

Transient transfection of Plasmodium vivax blood stage parasites

article

Transient transfection of Plasmodium vivax blood-stage parasites

scientific article published in January 2013

Transporters as mediators of drug resistance in Plasmodium falciparum

scientific article published on 24 April 2010

Virulence and drug resistance in malaria parasites

scientific article published on 4 September 2009

Willingness to pay for hypothetical malaria vaccines in rural Burkina Faso

scientific article

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