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List of works by Tom Huxford

A structural basis for IκB kinase 2 activation via oligomerization-dependent trans auto-phosphorylation

scientific article

Biochemical and Structural Characterization of Lysophosphatidic Acid Binding by a Humanized Monoclonal Antibody ⬇️

scientific article published on March 15, 2011

Biophysical characterization of the free IkappaBalpha ankyrin repeat domain in solution.

scientific article published in July 2004

Borate as a synergistic anion for Marinobacter algicola ferric binding protein, FbpA: a role for boron in iron transport in marine life

scientific article

Design of High-Affinity Metal-Controlled Protein Dimers

scientific article published on 12 April 2019

Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450BM3 Variants

scientific article

Genome reading by the NF-κB transcription factors

scientific article published on 01 November 2019

High-affinity pan-specific monoclonal antibodies that target cysteinyl leukotrienes and show efficacy in an acute model of colitis

scientific article published on 15 May 2017

Inhibition of transcription factor NF-kappaB activation by kappaB-Ras.

scientific article published in January 2006

IκBα Functions through Direct Contacts with the Nuclear Localization Signals and the DNA Binding Sequences of NF-κB ⬇️

scientific article published on September 25, 1998

NF-κB, IκB, and IKK: Integral Components of Immune System Signaling

scientific article published on 01 January 2019

Protein Cofactors Are Essential for High-Affinity DNA Binding by the Nuclear Factor κB RelA Subunit

scientific article

Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations

scientific article

The crystal structure of sphingosine-1-phosphate in complex with a Fab fragment reveals metal bridging of an antibody and its antigen

scientific article

The human IKKbeta subunit kinase domain displays CK2-like phosphorylation specificity.

scientific article published on 25 July 2008

The role of DNA in the mechanism of NFκB dimer formation: crystal structures of the dimerization domains of the p50 and p65 subunits ⬇️

scientific article published on November 15, 1997

Thermodynamics reveal that helix four in the NLS of NF-kappaB p65 anchors IkappaBalpha, forming a very stable complex.

scientific article published on 19 May 2006

Understanding the logic of IκB:NF-κB regulation in structural terms.

scientific article published on January 2011

X-ray Crystallographic and Molecular Dynamic Analyses of Drosophila melanogaster Embryonic Muscle Myosin Define Domains Responsible for Isoform-Specific Properties

scientific article published on 29 November 2019

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