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List of works by Andrew T Magis

A Multi-omic Association Study of Trimethylamine N-Oxide

scientific article published on 01 July 2018

A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer.

scientific article published on August 2009

A shift in the salt bridge interaction of residues D620 and E621 mediates the constitutive activation of Jak2-H538Q/K539L.

scientific article

A small molecule focal adhesion kinase (FAK) inhibitor, targeting Y397 site: 1-(2-hydroxyethyl)-3, 5, 7-triaza-1-azoniatricyclo [3.3.1.1(3,7)]decane; bromide effectively inhibits FAK autophosphorylation activity and decreases cancer cell viability,

scientific article published on 07 March 2012

A small-molecule inhibitor, 5'-O-tritylthymidine, targets FAK and Mdm-2 interaction, and blocks breast and colon tumorigenesis in vivo.

scientific article published on May 2013

A wellness study of 108 individuals using personal, dense, dynamic data clouds

scientific article published on 17 July 2017

A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth ⬇️

scientific article published on October 20, 2011

AUREA: an open-source software system for accurate and user-friendly identification of relative expression molecular signatures.

scientific article

Blood metabolome predicts gut microbiome α-diversity in humans

scientific article published on 02 September 2019

Crystallization and X-ray diffraction analysis of a novel immune-type receptor from Ictalurus punctatus and phasing by selenium anomalous dispersion methods.

scientific article published on 21 November 2007

Crystallization and preliminary X-ray analysis of the human long myosin light-chain kinase 1-specific domain IgCAM3.

scientific article

Crystallization of the focal adhesion kinase targeting (FAT) domain in a primitive orthorhombic space group.

scientific article published on 30 May 2008

Design, synthesis, and biological evaluation of novel FAK scaffold inhibitors targeting the FAK-VEGFR3 protein-protein interaction.

scientific article

Detection of 1α,25-dihydroxyvitamin D-regulated miRNAs in zebrafish by whole transcriptome sequencing

scientific article

Genetic Predisposition Impacts Clinical Changes in a Lifestyle Coaching Program

article

Genomic, Transcriptional, and Phenotypic Analysis of the Glucose Derepressed Clostridium beijerinckii Mutant Exhibiting Acid Crash Phenotype

scientific article published in August 2017

Graphics processing unit implementations of relative expression analysis algorithms enable dramatic computational speedup ⬇️

scientific article published on January 20, 2011

Gut microbiome pattern reflects healthy ageing and predicts survival in humans

scientific article published on 18 February 2021

Habitual sleep duration and sleep duration variation are independently associated with body mass index

scientific article

Inhibiting the Interaction of cMET and IGF-1R with FAK Effectively Reduces Growth of Pancreatic Cancer Cells in vitro and in vivo ⬇️

scientific article published on May 1, 2013

Kinetic characterization of newly discovered inhibitors of various constructs of human T-cell leukemia virus-1 (HTLV-1) protease and their effect on HTLV-1-infected cells.

scientific article

Mcl-1 Interacts with Akt to Promote Lung Cancer Progression

scientific article published on 29 October 2019

Measuring the effect of inter-study variability on estimating prediction error.

scientific article

Mitoxantrone targets the ATP-binding site of FAK, binds the FAK kinase domain and decreases FAK, Pyk-2, c-Src, and IGF-1R in vitro kinase activities

scientific article published on May 2013

Modulation of Bax and mTOR for Cancer Therapeutics.

scientific article published on 5 April 2017

Multi-Omic Biological Age Estimation and Its Correlation With Wellness and Disease Phenotypes: A Longitudinal Study of 3,558 Individuals

scientific article published on 01 November 2019

Multi-study integration of brain cancer transcriptomes reveals organ-level molecular signatures

scientific article

Multiomic blood correlates of genetic risk identify presymptomatic disease alterations

scientific article published on 19 August 2020

Noise contributions in an inducible genetic switch: a whole-cell simulation study

scientific article

Novel small-molecule inhibitors of Bcl-XL to treat lung cancer.

scientific article

Reply to "Precision medicine in the clouds"

scientific article published on 01 August 2018

SNAPR: a bioinformatics pipeline for efficient and accurate RNA-seq alignment and analysis.

scientific article published on 28 August 2015

Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy

scientific article published on 10 April 2019

Small molecule chloropyramine hydrochloride (C4) targets the binding site of focal adhesion kinase and vascular endothelial growth factor receptor 3 and suppresses breast cancer growth in vivo.

scientific article published on August 2009

Small-Molecule Bcl2 BH4 Antagonist for Lung Cancer Therapy

scientific article

Structure-function correlation of G6, a novel small molecule inhibitor of Jak2: indispensability of the stilbenoid core.

scientific article

Sulfatide Preserves Insulin Crystals Not by Being Integrated in the Lattice but by Stabilizing Their Surface

scientific article published on 14 February 2016

The constitutive activation of Jak2-V617F is mediated by a π stacking mechanism involving phenylalanines 595 and 617.

scientific article

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