List of works by Aartjan J W te Velthuis

A Mechanism for Priming and Realignment during Influenza A Virus Replication.

scientific article published on 8 November 2017

A SARS-CoV-2 mini-genome assay based on negative-sense RNA to study replication inhibitors and emerging mutations

scientific article published on 28 June 2021

Assays to Measure the Activity of Influenza Virus Polymerase

scientific article published on 01 January 2018

Common and unique features of viral RNA-dependent polymerases

scientific article

Comparative analysis of splice form-specific expression of LIM Kinases during zebrafish development.

scientific article published on 29 December 2006

Enisamium Inhibits SARS-CoV-2 RNA Synthesis

scientific article published on 17 September 2021

Enisamium Reduces Influenza Virus Shedding and Improves Patient Recovery by Inhibiting Viral RNA Polymerase Activity

scientific article published on 18 March 2021

Enisamium is a small molecule inhibitor of the influenza A virus and SARS-CoV-2 RNA polymerases

scientific article published on 22 April 2020

Erratum for Nilsson et al., "Role of the PB2 627 Domain in Influenza A Virus Polymerase Function".

scientific article published on 26 May 2017

Flu transcription captured in action

scientific article published on 01 June 2019

Gene expression patterns of the ALP family during zebrafish development

scientific article published on 7 September 2006

Genome-wide analysis of PDZ domain binding reveals inherent functional overlap within the PDZ interaction network

scientific article

Host restriction of influenza virus polymerase activity by PB2 627E is diminished on short viral templates in a nucleoprotein-independent manner.

scientific article published on 23 October 2013

Influenza Virus RNA Synthesis and the Innate Immune Response

scientific article published on 28 April 2021

Influenza virus RNA polymerase: insights into the mechanisms of viral RNA synthesis

scientific article

Initiation, elongation and realignment during influenza virus mRNA synthesis.

scientific article published on 15 November 2017

Insights into the molecular evolution of the PDZ/LIM family and identification of a novel conserved protein motif

scientific article

Integrity of the early secretory pathway promotes, but is not required for, severe acute respiratory syndrome coronavirus RNA synthesis and virus-induced remodeling of endoplasmic reticulum membranes

scientific article

Large virus for an even bigger task: can the mimivirus close the gene-therapy vector void?

scientific article published in May 2009

Linking fold, function and phylogeny: a comparative genomics view on protein (domain) evolution.

scientific article published on April 2008

Mechanism of nucleic acid unwinding by SARS-CoV helicase.

scientific article

Mini viral RNAs act as innate immune agonists during influenza virus infection

article

Molecular evolution of the MAGUK family in metazoan genomes

scientific article

Nidovirus RNA polymerases: Complex enzymes handling exceptional RNA genomes

scientific article published on 4 February 2017

PDZ and LIM domain-encoding genes: molecular interactions and their role in development.

scientific article published in September 2007

Quantitative Guidelines for Force Calibration Through Spectral Analysis of Magnetic Tweezers Data

Quantitative guidelines for force calibration through spectral analysis of magnetic tweezers data.

scientific article

RNA structure modulates Cas13 activity and enables mismatch detection

scholarly article

Real-time analysis of single influenza virus replication complexes reveals large promoter-dependent differences in initiation dynamics

scientific article published on 01 July 2019

Relative role of community transmission and campus contagion in driving the spread of SARS-CoV-2: Lessons from Princeton University

scientific article published in July 2023

Role of the PB2 627 Domain in Influenza A Virus Polymerase Function

scientific article published on 25 January 2017

Single-Cell Virus Sequencing of Influenza Infections That Trigger Innate Immunity

scientific article published on 28 June 2019

Single-molecule FRET reveals the pre-initiation and initiation conformations of influenza virus promoter RNA.

scientific article

Structural insights into RNA polymerases of negative-sense RNA viruses

scientific article

Structure and Function of the Influenza Virus Transcription and Replication Machinery

scientific article published on 30 December 2019

The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent

scientific article published on 29 October 2009

The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent

scientific article published on 16 November 2011

The RNA-dependent RNA polymerase of the influenza A virus

scientific article published on September 2014

The SARS-coronavirus nsp7+nsp8 complex is a unique multimeric RNA polymerase capable of both de novo initiation and primer extension

scientific article published on 29 October 2011

The lim domain only protein 7 is important in zebrafish heart development

scientific article published in December 2008

The mechanism of resistance to favipiravir in influenza

article published in the Proceedings of the National Academy of Sciences of the United States of America

The nature of protein domain evolution: shaping the interaction network

scientific article (publication date: August 2010)

The nested open reading frame in the Epstein-Barr virus nuclear antigen-1 mRNA encodes a protein capable of inhibiting antigen presentation in cis.

scientific article published on 20 April 2007

The role of the priming loop in influenza A virus RNA synthesis

scientific article

Transient RNA structures cause aberrant influenza virus replication and innate immune activation

scientific article published on 26 January 2022

Uncoupling of influenza A virus transcription and replication through mutation of the unpaired adenosine in the viral RNA promoter.

scientific article published on 17 July 2013

Zinc-Embedded Polyamide Fabrics Inactivate SARS-CoV-2 and Influenza A Virus

scientific article published on 7 July 2021

Zinc-embedded fabrics inactivate SARS-CoV-2 and influenza A virus

scientific article published on 04 November 2020

Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture

scientific article