List of works - Letizia Giampietro

Anticancer Activity of Stilbene-Based Derivatives.

scientific article published on 7 March 2017

Benzothiazole-based N-(phenylsulfonyl)amides as a novel family of PPARα antagonists

scientific article published on 01 August 2011

Blocking the peroxisome proliferator-activated receptor (PPAR): an overview.

scientific article published on 12 August 2013

Candida rugosa lipase-catalysed kinetic resolution of 2-substituted-aryloxyacetic esters with dimethylsulfoxide and isopropanol as additives.

scientific article published in February 2008

Cytotoxic effect of a family of peroxisome proliferator-activated receptor antagonists in colorectal and pancreatic cancer cell lines.

scientific article published on 23 May 2017

Development of Fibrates as Important Scaffolds in Medicinal Chemistry

scientific article published on 07 May 2019

Different binding and recognition modes of GL479, a dual agonist of Peroxisome Proliferator-Activated Receptor α/γ

scientific article

Discovery of N-{3-[(ethanimidoylamino)methyl]benzyl}-l-prolinamide dihydrochloride: A new potent and selective inhibitor of the inducible nitric oxide synthase as a promising agent for the therapy of malignant glioma.

scientific article

Discovery of gemfibrozil analogues that activate PPARα and enhance the expression of gene CPT1A involved in fatty acids catabolism.

scientific article published on 23 August 2011

Discovery of new FXR agonists based on 6-ECDCA binding properties by virtual screening and molecular docking

scientific article published on 04 July 2018

Druggability profile of stilbene-derived PPAR agonists: determination of physicochemical properties and PAMPA study

scientific article published on 15 August 2019

Enantiomeric separation of gemfibrozil chiral analogues by capillary electrophoresis with heptakis(2,3,6-tri-O-methyl)-beta-cyclodextrin as chiral selector.

scientific article published in September 2005

Fibrate-derived N-(methylsulfonyl)amides with antagonistic properties on PPARα

scientific article published on 23 October 2012

Identification of new anti-Candida compounds by ligand-based pharmacophore virtual screening.

scientific article

Indazole, Pyrazole, and Oxazole Derivatives Targeting Nitric Oxide Synthases and Carbonic Anhydrases.

scientific article published on 5 July 2016

N-Substituted acetamidines and 2-methylimidazole derivatives as selective inhibitors of neuronal nitric oxide synthase.

scientific article published on 17 September 2010

N-acylsulfonamides: Synthetic routes and biological potential in medicinal chemistry

scientific article

QSAR, QSPR and QSRR in Terms of 3-D-MoRSE Descriptors for In Silico Screening of Clofibric Acid Analogues.

scientific article published on 27 June 2012

Reversed-phase high-performance liquid chromatography method with fluorescence detection to screen nitric oxide synthases inhibitors

scientific article published on 29 April 2014

Screening of NOS activity and selectivity of newly synthesized acetamidines using RP-HPLC

scientific article published on 02 December 2015

Selective Acetamidine-Based Nitric Oxide Synthase Inhibitors: Synthesis, Docking, and Biological Studies.

scientific article published on 28 April 2015

Selective inhibition of iNOS by benzyl- and dibenzyl derivatives of N-(3-aminobenzyl)acetamidine

scientific article published on 12 May 2011

Selective inhibition of inducible nitric oxide synthase by derivatives of acetamidine.

scientific article

Structural development studies of PPARs ligands based on tyrosine scaffold

scientific article published on 31 October 2014

Synthesis and Biological Evaluation of Halogenated <i>E</i>-Stilbenols as Promising Antiaging Agents

scientific article published on 07 December 2020

Synthesis and antiplatelet activity of thioaryloxyacids analogues of clofibric acid.

scientific article published on 13 June 2005

Synthesis and biological characterization of 3-(imidazol-1-ylmethyl)piperidine sulfonamides as aromatase inhibitors

scientific article published on 28 April 2016

Synthesis and biological evaluation of 2-heteroarylthioalkanoic acid analogues of clofibric acid as peroxisome proliferator-activated receptor alpha agonists.

scientific article published on October 2009

Synthesis and structure-activity relationships of fibrate-based analogues inside PPARs

scientific article published on 06 October 2012

Synthesis of Naphthyl-, Quinolin- and Anthracenyl Analogues of Clofibric Acid as PPARα Agonists

scientific article published on 20 November 2015

Synthesis, biological evaluation, and docking studies of N-substituted acetamidines as selective inhibitors of inducible nitric oxide synthase.

scientific article published in March 2009

Synthesis, in vitro evaluation, and molecular modeling investigation of benzenesulfonimide peroxisome proliferator-activated receptors α antagonists

scientific article published on 27 February 2016

List of works by Letizia Giampietro

Anticancer Activity of Stilbene-Based Derivatives.

Benzothiazole-based N-(phenylsulfonyl)amides as a novel family of PPARα antagonists

Blocking the peroxisome proliferator-activated receptor (PPAR): an overview.

Candida rugosa lipase-catalysed kinetic resolution of 2-substituted-aryloxyacetic esters with dimethylsulfoxide and isopropanol as additives.

Cytotoxic effect of a family of peroxisome proliferator-activated receptor antagonists in colorectal and pancreatic cancer cell lines.

Development of Fibrates as Important Scaffolds in Medicinal Chemistry

Different binding and recognition modes of GL479, a dual agonist of Peroxisome Proliferator-Activated Receptor α/γ

Discovery of N-{3-[(ethanimidoylamino)methyl]benzyl}-l-prolinamide dihydrochloride: A new potent and selective inhibitor of the inducible nitric oxide synthase as a promising agent for the therapy of malignant glioma.

Discovery of gemfibrozil analogues that activate PPARα and enhance the expression of gene CPT1A involved in fatty acids catabolism.

Discovery of new FXR agonists based on 6-ECDCA binding properties by virtual screening and molecular docking

Druggability profile of stilbene-derived PPAR agonists: determination of physicochemical properties and PAMPA study

Enantiomeric separation of gemfibrozil chiral analogues by capillary electrophoresis with heptakis(2,3,6-tri-O-methyl)-beta-cyclodextrin as chiral selector.

Fibrate-derived N-(methylsulfonyl)amides with antagonistic properties on PPARα

Identification of new anti-Candida compounds by ligand-based pharmacophore virtual screening.

Indazole, Pyrazole, and Oxazole Derivatives Targeting Nitric Oxide Synthases and Carbonic Anhydrases.

N-Substituted acetamidines and 2-methylimidazole derivatives as selective inhibitors of neuronal nitric oxide synthase.

N-acylsulfonamides: Synthetic routes and biological potential in medicinal chemistry

QSAR, QSPR and QSRR in Terms of 3-D-MoRSE Descriptors for In Silico Screening of Clofibric Acid Analogues.

Reversed-phase high-performance liquid chromatography method with fluorescence detection to screen nitric oxide synthases inhibitors

Screening of NOS activity and selectivity of newly synthesized acetamidines using RP-HPLC

Selective Acetamidine-Based Nitric Oxide Synthase Inhibitors: Synthesis, Docking, and Biological Studies.

Selective inhibition of iNOS by benzyl- and dibenzyl derivatives of N-(3-aminobenzyl)acetamidine

Selective inhibition of inducible nitric oxide synthase by derivatives of acetamidine.

Structural development studies of PPARs ligands based on tyrosine scaffold

Synthesis and Biological Evaluation of Halogenated <i>E</i>-Stilbenols as Promising Antiaging Agents

Synthesis and antiplatelet activity of thioaryloxyacids analogues of clofibric acid.

Synthesis and biological characterization of 3-(imidazol-1-ylmethyl)piperidine sulfonamides as aromatase inhibitors

Synthesis and biological evaluation of 2-heteroarylthioalkanoic acid analogues of clofibric acid as peroxisome proliferator-activated receptor alpha agonists.

Synthesis and structure-activity relationships of fibrate-based analogues inside PPARs

Synthesis of Naphthyl-, Quinolin- and Anthracenyl Analogues of Clofibric Acid as PPARα Agonists

Synthesis, biological evaluation, and docking studies of N-substituted acetamidines as selective inhibitors of inducible nitric oxide synthase.

Synthesis, in vitro evaluation, and molecular modeling investigation of benzenesulfonimide peroxisome proliferator-activated receptors α antagonists