Search filters

List of works by James Costello

"Reverse ecology" and the power of population genomics

scientific article

<i>MAP3K7</i> Loss Drives Enhanced Androgen Signaling and Independently Confers Risk of Recurrence in Prostate Cancer with Joint Loss of <i>CHD1</i>

scientific article published on 12 April 2021

A DREAM Challenge to Build Prediction Models for Short-Term Discontinuation of Docetaxel in Metastatic Castration-Resistant Prostate Cancer

scientific article published on 01 November 2017

A Gene Expression Signature Predicts Bladder Cancer Cell Line Sensitivity to EGFR Inhibition

scientific article published on 30 July 2018

A SIX1/EYA2 small molecule inhibitor disrupts EMT and metastasis

scientific article published on 27 April 2020

A SPATIOTEMPORAL MODEL TO SIMULATE CHEMOTHERAPY REGIMENS FOR HETEROGENEOUS BLADDER CANCER METASTASES TO THE LUNG.

scientific article published on January 2016

A Whole-genome CRISPR Screen Identifies a Role of MSH2 in Cisplatin-mediated Cell Death in Muscle-invasive Bladder Cancer

scientific article published on 07 November 2018

All Paths Lead to TRIM25.

scientific article published in October 2017

Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes.

scientific article published in December 2017

Bactericidal antibiotics induce mitochondrial dysfunction and oxidative damage in Mammalian cells.

scientific article published on July 2013

Combined administration of testosterone plus an ornithine decarboxylase inhibitor as a selective prostate-sparing anabolic therapy

scientific article

Community mining of open clinical trial data.

scientific article published on 13 September 2017

Concurrent alterations in TERT, KDM6A, and the BRCA pathway in bladder cancer.

scientific article

Coordinate loss of MAP3K7 and CHD1 promotes aggressive prostate cancer

scientific article

Crowdsourcing biomedical research: leveraging communities as innovation engines

scientific article (publication date: 15 July 2016)

DREAMTools: a Python package for scoring collaborative challenges.

scientific article

Data pushing: a fly-centric guide to bioinformatics tools.

scientific article

Decade in review-bladder cancer: international progress: from cytology to genomics.

scientific article published on 02 September 2014

Differential splicing across immune system lineages

scientific article published on 09 August 2013

EST and microarray analysis of horn development in Onthophagus beetles

scientific article

Eya3 promotes breast tumor-associated immune suppression via threonine phosphatase-mediated PD-L1 upregulation

scientific article published on 14 May 2018

GON4L Drives Cancer Growth through a YY1-Androgen Receptor-CD24 Axis

scientific article

GSEA-InContext: identifying novel and common patterns in expression experiments.

scientific article published in July 2018

Gene networks in Drosophila melanogaster: integrating experimental data to predict gene function

scientific article

Homeoprotein Six2 promotes breast cancer metastasis via transcriptional and epigenetic control of E-cadherin expression

scientific article

Induction of ADAM10 by Radiation Therapy Drives Fibrosis, Resistance, and Epithelial-to-Mesenchyal Transition in Pancreatic Cancer

publication published on 01 February 2021

KDM3A/Ets1 epigenetic axis contributes to PAX3/FOXO1-driven and independent disease-promoting gene expression in fusion-positive Rhabdomyosarcoma

scientific article published on 22 July 2020

Loss of MAP3K7 Sensitizes Prostate Cancer Cells to CDK1/2 Inhibition and DNA Damage by Disrupting Homologous Recombination

scientific article published on 12 July 2019

Mediator of DNA Damage Checkpoint 1 (MDC1) Is a Novel Estrogen Receptor Coregulator in Invasive Lobular Carcinoma of the Breast

scientific article published on 04 May 2021

Mesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple Cancers

scientific article published on 10 April 2020

Metastatic cells are preferentially vulnerable to lysosomal inhibition

scientific article published on 20 August 2018

Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response

scientific article published on 06 June 2016

Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia

scientific article published on 23 January 2020

Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.

scientific article published on September 2016

Next-Generation Machine Learning for Biological Networks

scientific article published on 07 June 2018

Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open clinical trial data

scientific article

Research resource: EPSLiM: ensemble predictor for short linear motifs in nuclear hormone receptors.

scientific article

RhoC Is an Unexpected Target of RhoGDI2 in Prevention of Lung Colonization of Bladder Cancer.

scientific article

SIX2 Mediates Late-Stage Metastasis via Direct Regulation of SOX2 and Induction of a Cancer Stem Cell Program

scientific article published on 03 January 2019

Seeking the wisdom of crowds through challenge-based competitions in biomedical research.

scientific article

Simulating heterogeneous populations using Boolean models.

scientific article

Systematic Review: Characteristics and Preclinical Uses of Bladder Cancer Cell Lines.

scientific article

Targeting DDR2 enhances tumor response to anti-PD-1 immunotherapy

article

The capacity of the ovarian cancer tumor microenvironment to integrate inflammation signaling conveys a shorter disease-free interval

scientific article published on 14 September 2020

Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors

scientific article published on 18 October 2019

Troubleshooting microarray hybridizations.

scientific article published on January 2006

Tumor-Derived Cell Lines as Molecular Models of Cancer Pharmacogenomics

scientific article

Paulina is supported by:

About Paulina

Help