List of works - Hayato Nakagawa

A Novel Non-invasive Method for Predicting Liver Fibrosis by Quantifying the Hepatic Vein Waveform

scientific article published on 12 July 2019

A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion

scientific article

Activation of IkappaB kinase and NF-kappaB is essential for Helicobacter pylori-induced chronic gastritis in Mongolian gerbils.

scientific article published on 10 December 2007

Adhesive Interactions between Mononuclear Phagocytes and Intestinal Epithelium Perturb Normal Epithelial Differentiation and Serve as a Therapeutic Target in Inflammatory Bowel Disease

scientific article published on 01 November 2018

Altered composition of fatty acids exacerbates hepatotumorigenesis during activation of the phosphatidylinositol 3-kinase pathway.

scientific article published on 19 May 2011

Altered serum acylcarnitine profile is associated with the status of nonalcoholic fatty liver disease (NAFLD) and NAFLD-related hepatocellular carcinoma

scientific article published on 23 July 2019

Anti-tumor activity of the proteasome inhibitor bortezomib in gastric cancer.

scientific article

Apoptosis signal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling the tumor-suppressing function of stress-activated mitogen-activated protein kinase.

scientific article

Apoptosis signal-regulating kinase-1 inhibitor as a potent therapeutic drug for the treatment of gastric cancer.

scientific article

Autotaxin as a novel serum marker of liver fibrosis.

scientific article published on 17 March 2011

Biliary epithelial injury-induced regenerative response by IL-33 promotes cholangiocarcinogenesis from peribiliary glands

scientific article published on 24 April 2017

CPT2 downregulation adapts HCC to lipid-rich environment and promotes carcinogenesis via acylcarnitine accumulation in obesity.

scientific article published on 6 February 2018

Comparison of improved prognosis between hepatitis B- and hepatitis C-related hepatocellular carcinoma

scientific article published on 6 January 2015

Corrigendum: A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion

scientific article published on 3 January 2017

Cutting edge: The IkappaB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks inflammatory injury in murine colitis

scientific article published on 01 September 2007

Eculizumab treatment for ischemic enteritis accompanied with paroxysmal nocturnal hemoglobinuria: a case report and literature review

scientific article published on 13 March 2018

Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis.

scientific article published on 26 June 2009

Frequency of and predictive factors for vascular invasion after radiofrequency ablation for hepatocellular carcinoma.

scientific article

Frequency, risk factors and survival associated with an intrasubsegmental recurrence after radiofrequency ablation for hepatocellular carcinoma.

scientific article

GPR30-Expressing Gastric Chief Cells Do Not Dedifferentiate But Are Eliminated via PDK-Dependent Cell Competition During Development of Metaplasia

scientific article published on 04 February 2020

Hepatic FATP5 expression is associated with histological progression and loss of hepatic fat in NAFLD patients

scientific article published on 10 October 2019

Hepatic IRS1 and ß-catenin expression is associated with histological progression and overt diabetes emergence in NAFLD patients.

scientific article

High ubiquitous mitochondrial creatine kinase expression in hepatocellular carcinoma denotes a poor prognosis with highly malignant potential.

scientific article

How endoplasmic reticulum stress contributes to obesity-driven hepatic tumorigenesis

scientific article published on 30 July 2015

Identification of liver fibrosis using the hepatic vein waveform in patients with Fontan circulation

scientific article published on 27 September 2018

Impact of AAV2 and Hepatitis B Virus Integration Into Genome on Development of Hepatocellular Carcinoma in Patients with Prior Hepatitis B Virus Infection

scientific article published on 18 July 2019

Impact of direct-acting antivirals on early recurrence of HCV-related HCC: comparison with interferon-based therapy

scientific article published on 16 October 2018

Impact of histone demethylase KDM3A-dependent AP-1 transactivity on hepatotumorigenesis induced by PI3K activation.

scientific article published on 10 July 2017

Impact of serum ferritin level on hepatocarcinogenesis in chronic hepatitis C patients

scientific article published on 18 March 2015

Impact of serum levels of interleukin-6 and adiponectin on all-cause, liver-related, and liver-unrelated mortality in chronic hepatitis C patients.

scientific article published on February 2015

Improved liver function in patients with cirrhosis due to chronic hepatitis C virus who achieve sustained virologic response is not accompanied by increased liver volume

scientific article published on 20 April 2020

Increased activity of serum mitochondrial isoenzyme of creatine kinase in hepatocellular carcinoma patients predominantly with recurrence.

scientific article

Increased serum autotaxin levels in hepatocellular carcinoma patients were caused by background liver fibrosis but not by carcinoma

scientific article published on 16 March 2014

Increased serum mitochondrial creatine kinase activity as a risk for hepatocarcinogenesis in chronic hepatitis C patients

scientific article

Inhibition of autophagy exerts anti-colon cancer effects via apoptosis induced by p53 activation and ER stress.

scientific article published on 24 October 2015

Inhibitor of kappaB kinase beta regulates gastric carcinogenesis via interleukin-1alpha expression.

scientific article published on 25 March 2010

Intrahepatic bile duct dilatation after percutaneous radiofrequency ablation for hepatocellular carcinoma: impact on patient's prognosis.

scientific article published on 15 December 2010

Ischemic complications after percutaneous radiofrequency ablation of liver tumors: Liver volume loss and recovery

scientific article published on 06 February 2019

Lipid Metabolic Reprogramming in Hepatocellular Carcinoma

scientific article published on 15 November 2018

Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling

scientific article published on 01 June 2018

Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition

scientific article published on 5 June 2014

Liver stiffness measurements in chronic hepatitis C: treatment evaluation and risk assessment

scientific article published on 07 December 2018

Mature gastric chief cells are not required for the development of metaplasia.

scientific article published on 18 January 2018

Molecular mechanisms of liver injury and hepatocarcinogenesis: focusing on the role of stress-activated MAPK

scientific article

Mouse Model for Cholangiocarcinoma from Peribiliary Glands

scientific article published on 01 January 2019

Mutant IDH1 confers resistance to energy stress in normal biliary cells through PFKP-induced aerobic glycolysis and AMPK activation

scientific article published on 11 December 2019

Perihepatic lymph node enlargement is a negative predictor for sustained responses to pegylated interferon-α and ribavirin therapy for Japanese patients infected with hepatitis C virus genotype 1.

scientific article published on 29 January 2013

Radiofrequency ablation for hepatocellular carcinoma: 10-year outcome and prognostic factors.

scientific article

Recent advances in mouse models of obesity- and nonalcoholic steatohepatitis-associated hepatocarcinogenesis.

scientific article published on August 2015

Recurrent Acute Liver Failure Because of Acute Hepatitis Induced by Organic Solvents: A Case Report

scientific article published on January 2016

Roles of E-cadherin in Hepatocarcinogenesis

Sarcopenia, intramuscular fat deposition, and visceral adiposity independently predict the outcomes of hepatocellular carcinoma.

scientific article published on 24 February 2015

Serum gamma-glutamyltransferase level is associated with serum superoxide dismutase activity and metabolic syndrome in a Japanese population

scientific article published on 06 October 2011

Serum level of adiponectin and the risk of liver cancer development in chronic hepatitis C patients

scientific article published on 29 March 2011

Serum levels of ferritin do not affect the prognosis of patients with hepatocellular carcinoma undergoing radiofrequency ablation

scientific article published on 25 July 2018

Slight elevation of high-sensitivity C-reactive protein to predict recurrence and survival in patients with early stage hepatitis C-related hepatocellular carcinoma.

scientific article published on 2 September 2014

Systemic combination therapy of intravenous continuous 5-fluorouracil and subcutaneous pegylated interferon alfa-2a for advanced hepatocellular carcinoma.

scientific article

TGF-β Signaling in Dendritic Cells Governs Colonic Homeostasis by Controlling Epithelial Differentiation and the Luminal Microbiota.

scientific article published on 22 April 2016

The impact of direct-acting antivirals on early tumor recurrence after radiofrequency ablation in hepatitis C-related hepatocellular carcinoma

scientific article published on 11 August 2016

Therapeutic effect of c-Jun N-terminal kinase inhibition on pancreatic cancer.

scientific article published on 24 January 2013

Three types of metaplasia model through Kras activation, Pten deletion, or Cdh1 deletion in the gastric epithelium

scientific article published on 27 November 2018

Tumor markers are more useful in patients undergoing surveillance for hepatocellular carcinoma with unreliable results by ultrasonography

scientific article published on 19 June 2014

Uninodular combined hepatocellular and cholangiocarcinoma with multiple non-neoplastic hypervascular lesions appearing in the liver of a patient with HIV and HCV coinfection.

scientific article published on 19 February 2013

List of works by Hayato Nakagawa

A Novel Non-invasive Method for Predicting Liver Fibrosis by Quantifying the Hepatic Vein Waveform

A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion

Activation of IkappaB kinase and NF-kappaB is essential for Helicobacter pylori-induced chronic gastritis in Mongolian gerbils.

Adhesive Interactions between Mononuclear Phagocytes and Intestinal Epithelium Perturb Normal Epithelial Differentiation and Serve as a Therapeutic Target in Inflammatory Bowel Disease

Altered composition of fatty acids exacerbates hepatotumorigenesis during activation of the phosphatidylinositol 3-kinase pathway.

Altered serum acylcarnitine profile is associated with the status of nonalcoholic fatty liver disease (NAFLD) and NAFLD-related hepatocellular carcinoma

Anti-tumor activity of the proteasome inhibitor bortezomib in gastric cancer.

Apoptosis signal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling the tumor-suppressing function of stress-activated mitogen-activated protein kinase.

Apoptosis signal-regulating kinase-1 inhibitor as a potent therapeutic drug for the treatment of gastric cancer.

Autotaxin as a novel serum marker of liver fibrosis.

Biliary epithelial injury-induced regenerative response by IL-33 promotes cholangiocarcinogenesis from peribiliary glands

CPT2 downregulation adapts HCC to lipid-rich environment and promotes carcinogenesis via acylcarnitine accumulation in obesity.

Comparison of improved prognosis between hepatitis B- and hepatitis C-related hepatocellular carcinoma

Corrigendum: A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion

Cutting edge: The IkappaB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks inflammatory injury in murine colitis

Eculizumab treatment for ischemic enteritis accompanied with paroxysmal nocturnal hemoglobinuria: a case report and literature review

Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis.

Frequency of and predictive factors for vascular invasion after radiofrequency ablation for hepatocellular carcinoma.

Frequency, risk factors and survival associated with an intrasubsegmental recurrence after radiofrequency ablation for hepatocellular carcinoma.

GPR30-Expressing Gastric Chief Cells Do Not Dedifferentiate But Are Eliminated via PDK-Dependent Cell Competition During Development of Metaplasia

Hepatic FATP5 expression is associated with histological progression and loss of hepatic fat in NAFLD patients

Hepatic IRS1 and ß-catenin expression is associated with histological progression and overt diabetes emergence in NAFLD patients.

High ubiquitous mitochondrial creatine kinase expression in hepatocellular carcinoma denotes a poor prognosis with highly malignant potential.

How endoplasmic reticulum stress contributes to obesity-driven hepatic tumorigenesis

Identification of liver fibrosis using the hepatic vein waveform in patients with Fontan circulation

Impact of AAV2 and Hepatitis B Virus Integration Into Genome on Development of Hepatocellular Carcinoma in Patients with Prior Hepatitis B Virus Infection

Impact of direct-acting antivirals on early recurrence of HCV-related HCC: comparison with interferon-based therapy

Impact of histone demethylase KDM3A-dependent AP-1 transactivity on hepatotumorigenesis induced by PI3K activation.

Impact of serum ferritin level on hepatocarcinogenesis in chronic hepatitis C patients

Impact of serum levels of interleukin-6 and adiponectin on all-cause, liver-related, and liver-unrelated mortality in chronic hepatitis C patients.

Improved liver function in patients with cirrhosis due to chronic hepatitis C virus who achieve sustained virologic response is not accompanied by increased liver volume

Increased activity of serum mitochondrial isoenzyme of creatine kinase in hepatocellular carcinoma patients predominantly with recurrence.

Increased serum autotaxin levels in hepatocellular carcinoma patients were caused by background liver fibrosis but not by carcinoma

Increased serum mitochondrial creatine kinase activity as a risk for hepatocarcinogenesis in chronic hepatitis C patients

Inhibition of autophagy exerts anti-colon cancer effects via apoptosis induced by p53 activation and ER stress.

Inhibitor of kappaB kinase beta regulates gastric carcinogenesis via interleukin-1alpha expression.

Intrahepatic bile duct dilatation after percutaneous radiofrequency ablation for hepatocellular carcinoma: impact on patient's prognosis.

Ischemic complications after percutaneous radiofrequency ablation of liver tumors: Liver volume loss and recovery

Lipid Metabolic Reprogramming in Hepatocellular Carcinoma

Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling

Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition

Liver stiffness measurements in chronic hepatitis C: treatment evaluation and risk assessment

Mature gastric chief cells are not required for the development of metaplasia.

Molecular mechanisms of liver injury and hepatocarcinogenesis: focusing on the role of stress-activated MAPK

Mouse Model for Cholangiocarcinoma from Peribiliary Glands

Mutant IDH1 confers resistance to energy stress in normal biliary cells through PFKP-induced aerobic glycolysis and AMPK activation

Perihepatic lymph node enlargement is a negative predictor for sustained responses to pegylated interferon-α and ribavirin therapy for Japanese patients infected with hepatitis C virus genotype 1.

Radiofrequency ablation for hepatocellular carcinoma: 10-year outcome and prognostic factors.

Recent advances in mouse models of obesity- and nonalcoholic steatohepatitis-associated hepatocarcinogenesis.

Recurrent Acute Liver Failure Because of Acute Hepatitis Induced by Organic Solvents: A Case Report

Roles of E-cadherin in Hepatocarcinogenesis

Sarcopenia, intramuscular fat deposition, and visceral adiposity independently predict the outcomes of hepatocellular carcinoma.

Serum gamma-glutamyltransferase level is associated with serum superoxide dismutase activity and metabolic syndrome in a Japanese population

Serum level of adiponectin and the risk of liver cancer development in chronic hepatitis C patients

Serum levels of ferritin do not affect the prognosis of patients with hepatocellular carcinoma undergoing radiofrequency ablation

Slight elevation of high-sensitivity C-reactive protein to predict recurrence and survival in patients with early stage hepatitis C-related hepatocellular carcinoma.

Systemic combination therapy of intravenous continuous 5-fluorouracil and subcutaneous pegylated interferon alfa-2a for advanced hepatocellular carcinoma.

TGF-β Signaling in Dendritic Cells Governs Colonic Homeostasis by Controlling Epithelial Differentiation and the Luminal Microbiota.

The impact of direct-acting antivirals on early tumor recurrence after radiofrequency ablation in hepatitis C-related hepatocellular carcinoma

Therapeutic effect of c-Jun N-terminal kinase inhibition on pancreatic cancer.

Three types of metaplasia model through Kras activation, Pten deletion, or Cdh1 deletion in the gastric epithelium

Tumor markers are more useful in patients undergoing surveillance for hepatocellular carcinoma with unreliable results by ultrasonography

Uninodular combined hepatocellular and cholangiocarcinoma with multiple non-neoplastic hypervascular lesions appearing in the liver of a patient with HIV and HCV coinfection.