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List of works by Adria Giacca

A low-protein diet combined with low-dose endotoxin leads to changes in glucose homeostasis in weanling rats

scientific article published on 7 July 2015

Acute effects of single-dose olanzapine on metabolic, endocrine, and inflammatory markers in healthy controls

scientific article published in December 2013

Anti-atherogenic effect of insulin in vivo.

scientific article published on 6 September 2005

Association of NEFA composition with insulin sensitivity and beta cell function in the Prospective Metabolism and Islet Cell Evaluation (PROMISE) cohort

scientific article published on 24 December 2017

Atypical antipsychotics and effects of adrenergic and serotonergic receptor binding on insulin secretion in-vivo: An animal model ⬇️

scientific article published on March 15, 2013

Chronic olanzapine administration in rats: Effect of route of administration on weight, food intake and body composition ⬇️

scientific article published on December 9, 2012

Combined Hyperglycemia and Hyperinsulinemia-induced Insulin Resistance in Adipocytes is associated with Dual Signaling Defects mediated by PKC-ζ.

scientific article published on 23 January 2018

Deficiency of a glycogen synthase-associated protein, Epm2aip1, causes decreased glycogen synthesis and hepatic insulin resistance

scientific journal article

Direct and indirect effects of insulin on hepatic glucose production in diabetic depancreatized dogs during euglycemia.

scientific article published in September 2006

Direct measure of insulin sensitivity with the hyperinsulinemic-euglycemic clamp and surrogate measures of insulin sensitivity with the oral glucose tolerance test: correlations with aberrant crypt foci promotion in rats.

scientific article published in January 2003

Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes

scientific article

Duration of rise in free fatty acids determines salicylate's effect on hepatic insulin sensitivity ⬇️

scientific article published on March 15, 2013

Effects of insulin and analogues on carcinogen-induced mammary tumours in high-fat-fed rats.

scientific article

Effects of insulin on the vasculature.

scientific article

Effects of intracerebroventricular (ICV) olanzapine on insulin sensitivity and secretion in vivo: an animal model

scientific article published on 13 August 2013

Effects of portal free fatty acid elevation on insulin clearance and hepatic glucose flux

scientific article published on 3 January 2006

Enhancing thermal stability of a highly concentrated insulin formulation with Pluronic F-127 for long-term use in microfabricated implantable devices

scientific article published on 20 April 2017

Evaluation of the specific effects of intranasal glucagon on glucose production and lipid concentration in healthy men during a pancreatic clamp

scientific article published on 20 July 2017

Exercise maintains euglycemia in association with decreased activation of c-Jun NH2-terminal kinase and serine phosphorylation of IRS-1 in the liver of ZDF rats

scientific article

FFA-induced hepatic insulin resistance in vivo is mediated by PKCδ, NADPH oxidase, and oxidative stress

scientific article

FK-614, a selective peroxisome proliferator-activated receptor gamma agonist, improves peripheral glucose utilization while decreasing hepatic insulin extraction in alloxan-induced diabetic dogs

scientific article published in September 2005

Free fatty acid-induced hepatic insulin resistance: a potential role for protein kinase C-delta

scientific article published in October 2002

Free fatty acid-mediated impairment of glucose-stimulated insulin secretion in nondiabetic Oji-Cree individuals from the Sandy Lake community of Ontario, Canada: a population at very high risk for developing type 2 diabetes

scientific article published in June 2003

Free fatty acids increase basal hepatic glucose production and induce hepatic insulin resistance at different sites

scientific article published in February 2003

Gene and protein kinase expression profiling of reactive oxygen species-associated lipotoxicity in the pancreatic beta-cell line MIN6.

scientific article published on January 2004

Hepatocyte-specific Deletion of Janus Kinase 2 (JAK2) Protects against Diet-induced Steatohepatitis and Glucose Intolerance ⬇️

scientific article published on January 24, 2012

High multivitamin intake by Wistar rats during pregnancy results in increased food intake and components of the metabolic syndrome in male offspring

scientific article published on 4 June 2008

High-dose metformin (420mg/kg daily p.o.) increases insulin sensitivity but does not affect neointimal thickness in the rat carotid balloon injury model of restenosis

scientific article published on 10 December 2016

Hyperglycemia after protein ingestion concurrent with injection of a GLP-1 receptor agonist in rats: a possible role for dietary peptides

scientific article published on 5 May 2005

Hyperinsulinemia, but not other factors associated with insulin resistance, acutely enhances colorectal epithelial proliferation in vivo

scientific article published on 12 January 2006

IKKβ inhibition prevents fat-induced beta cell dysfunction in vitro and in vivo in rodents

scientific article published on 20 July 2017

In male rats, the ability of central insulin to suppress glucose production is impaired by olanzapine, whereas glucose uptake is left intact

scientific article published in November 2017

In male rats, the ability of central insulin to suppress glucose production is impaired by olanzapine, whereas glucose uptake is left intact

scientific article

In vitro and in vivo testing of glucose-responsive insulin-delivery microdevices in diabetic rats ⬇️

scientific article published on May 8, 2012

In vivo effect of insulin to decrease matrix metalloproteinase-2 and -9 activity after arterial injury

scientific article

In vivo effects of polyunsaturated, monounsaturated, and saturated fatty acids on hepatic and peripheral insulin sensitivity

scientific article published on 25 October 2014

In vivo performance and biocompatibility of a subcutaneous implant for real-time glucose-responsive insulin delivery.

scientific article

Insulin decreases atherosclerotic plaque burden and increases plaque stability via nitric oxide synthase in apolipoprotein E-null mice

scientific article published on 24 May 2016

Insulin increases reendothelialization and inhibits cell migration and neointimal growth after arterial injury

scientific article published on 9 April 2009

Insulin inhibits and oral sucrose increases neointimal growth after arterial injury in rats

scientific article published on 6 February 2010

Insulin inhibits glucose production by a direct effect in diabetic depancreatized dogs during euglycemia

scientific article published in November 2002

Insulin resistance and decreased glucose-stimulated insulin secretion after acute olanzapine administration

scientific article

Insulin resistance and secretion in vivo: effects of different antipsychotics in an animal model

scientific article published on 20 January 2009

Insulin resistance following continuous, chronic olanzapine treatment: an animal model

scientific article published in September 2008

Lipid-induced beta-cell dysfunction in vivo in models of progressive beta-cell failure

scientific article published on 26 September 2006

Lipid-induced pancreatic β-cell dysfunction: focus on in vivo studies

scientific article

Local insulin application on the carotid artery inhibits neointima formation

scientific article published on 12 September 2013

Longitudinal Associations of Phospholipid and Cholesteryl Ester Fatty Acids With Disorders Underlying Diabetes

scientific article published on 4 May 2016

Maternal taurine supplementation in rats partially prevents the adverse effects of early-life protein deprivation on β-cell function and insulin sensitivity

scientific article published on 21 May 2013

Mechanisms of the free fatty acid-induced increase in hepatic glucose production

scientific article

Metformin attenuates olanzapine-induced hepatic, but not peripheral insulin resistance

scientific article published in September 2015

Microfabricated microporous membranes reduce the host immune response and prolong the functional lifetime of a closed-loop insulin delivery implant in a type 1 diabetic rat model

scientific article published on 4 February 2015

Muscle-specific Pten deletion protects against insulin resistance and diabetes

scientific article

N-acetylcysteine and taurine prevent hyperglycemia-induced insulin resistance in vivo: possible role of oxidative stress

scientific article

NOD1 Activators Link Innate Immunity to Insulin Resistance ⬇️

scientific article published on June 29, 2011

O10.6. OLANZAPINE IMPAIRS CENTRAL INSULIN ACTION: EFFECTS ON BODY FUEL PREFERENCE IN RATS.

scientific article

Oleate-induced decrease in hepatocyte insulin binding is mediated by PKC-delta.

scientific article

Overexpression of glutathione peroxidase 4 prevents β-cell dysfunction induced by prolonged elevation of lipids in vivo

scientific article

Pharmacologic or genetic activation of SIRT1 attenuates the fat-induced decrease in beta-cell function in vivo

Plasma nonesterified Fatty Acid intolerance and hyperglycemia are associated with intravenous lipid-induced impairment of insulin sensitivity and disposition index

scientific article published on 22 January 2010

Resveratrol inhibits neointimal formation after arterial injury through an endothelial nitric oxide synthase-dependent mechanism ⬇️

scientific article published on March 27, 2012

Resveratrol prevents insulin resistance caused by short-term elevation of free fatty acids in vivo

scientific article published on 10 July 2015

Risk factors for colorectal cancer in man induce aberrant crypt foci in rats: Preliminary findings

scientific article published on 28 December 2015

Salicylate prevents hepatic insulin resistance caused by short-term elevation of free fatty acids in vivo

scientific article published in November 2007

Severe hypoglycemia in a juvenile diabetic rat model: presence and severity of seizures are associated with mortality

scientific article

Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and beta-cell dysfunction in humans

scientific article

Somatostatin Receptor Type 2 Antagonism Improves Glucagon and Corticosterone Counterregulatory Responses to Hypoglycemia in Streptozotocin-Induced Diabetic Rats ⬇️

scientific article published on November 21, 2011

Stimulation of muscle cell glucose uptake by resveratrol through sirtuins and AMPK.

scientific article

Susceptibility to Fatty Acid-Induced β-Cell Dysfunction Is Enhanced in Prediabetic Diabetes-Prone BioBreeding Rats: A Potential Link Between β-Cell Lipotoxicity and Islet Inflammation ⬇️

scientific article published on November 13, 2012

The composition of dietary fat directly influences glucose-stimulated insulin secretion in rats

scientific article published in June 2002

The effect of chronic insulin delivery via the intraperitoneal versus the subcutaneous route on hepatic triglyceride secretion rate in streptozotocin diabetic rats

scientific article published in April 2002

The effect of high-dose sodium salicylate on chronically elevated plasma nonesterified fatty acid-induced insulin resistance and β-cell dysfunction in overweight and obese nondiabetic men.

scientific article published on 15 September 2009

The effect of insulin to decrease neointimal growth after arterial injury is endothelial nitric oxide synthase-dependent

scientific article published on 25 April 2015

The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species

scientific article published on 9 November 2004

UCP2 is highly expressed in pancreatic alpha-cells and influences secretion and survival

scholarly article

Vasopeptidase inhibitor omapatrilat induces profound insulin sensitization and increases myocardial glucose uptake in Zucker fatty rats: Studies comparing a vasopeptidase inhibitor, angiotensin-converting enzyme inhibitor, and angiotensin II type I

scientific article published on 31 March 2003

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