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List of works by Isaac Jardín

(-)‑Oleocanthal inhibits proliferation and migration by modulating Ca entry through TRPC6 in breast cancer cells

scientific article published on 12 October 2018

A calcium-accumulating region, CAR, in the channel Orai1 enhances Ca(2+) permeation and SOCE-induced gene transcription

scientific article published on 22 December 2015

Apelin: an antithrombotic factor that inhibits platelet function.

scientific article published on 3 December 2015

Attenuated store-operated divalent cation entry and association between STIM1, Orai1, hTRPC1 and hTRPC6 in platelets from type 2 diabetic patients

scientific article published on 01 March 2011

Ca2+leakage rate from agonist-sensitive intracellular pools is altered in platelets from patients with type 2 diabetes ⬇️

scientific article published on April 28, 2011

Canonical transient receptor potential (TRPC) 1 acts as a negative regulator for vanilloid TRPV6-mediated Ca2+ influx.

scientific article published on 29 August 2012

Cholesterol modulates Orai1 channel function

scientific article published on 26 January 2016

Cinnamtannin B-1 as an antioxidant and platelet aggregation inhibitor.

scientific article published on 29 March 2008

Complex role of STIM1 in the activation of store-independent Orai1/3 channels.

scientific article published on March 2014

Differential involvement of thrombin receptors in Ca2+ release from two different intracellular stores in human platelets.

scientific article published on January 2007

Dynamic interaction of hTRPC6 with the Orai1-STIM1 complex or hTRPC3 mediates its role in capacitative or non-capacitative Ca(2+) entry pathways.

scientific article published on 13 May 2009

EFHB is a Novel Cytosolic Ca2+ Sensor That Modulates STIM1-SARAF Interaction

scientific article published on 27 November 2018

Effect of homocysteine on calcium mobilization and platelet function in type 2 diabetes mellitus.

scientific article published in October 2008

Endogenously generated reactive oxygen species reduce PMCA activity in platelets from patients with non-insulin-dependent diabetes mellitus

scientific article published on 01 August 2006

Filamin A Modulates Store-Operated Ca2+ Entry by Regulating STIM1 (Stromal Interaction Molecule 1)-Orai1 Association in Human Platelets.

scientific article

Filamin A modulates platelet function

Fine-tuning of microRNAs in type 2 diabetes mellitus

scientific article published on 5 December 2017

Fine-tuning of store-operated calcium entry by fast and slow Ca2+-dependent inactivation: Involvement of SARAF.

scientific article published on 6 December 2017

Flavonoids and platelet-derived thrombotic disorders.

scientific article published on 17 April 2018

Homer proteins in Ca²⁺ entry.

scientific article published on 03 April 2013

Homers regulate calcium entry and aggregation in human platelets: a role for Homers in the association between STIM1 and Orai1

scientific article published on 01 July 2012

Homocysteine, intracellular signaling and thrombotic disorders.

scientific article published on January 2010

Hydrogen peroxide and peroxynitrite enhance Ca2+ mobilization and aggregation in platelets from type 2 diabetic patients.

scientific article published in August 2005

Intracellular Ca2+ store depletion induces the formation of macromolecular complexes involving hTRPC1, hTRPC6, the type II IP3 receptor and SERCA3 in human platelets.

scientific article

Involvement of SNARE proteins in thrombin-induced platelet aggregation: evidence for the relevance of Ca2+ entry

scientific article published on 21 May 2007

Involvement of stanniocalcins in the deregulation of glycaemia in obese mice and type 2 diabetic patients.

scientific article published on 9 October 2017

Lipid rafts are essential for the regulation of SOCE by plasma membrane resident STIM1 in human platelets

scientific article published on 19 January 2011

Melatonin downregulates TRPC6, impairing store-operated calcium entry in triple negative breast cancer cells

scientific article published on 30 December 2020

Melatonin, as an adjuvant-like agent, enhances platelet responsiveness.

scientific article published on 31 January 2009

Molecular mechanisms of STIM/Orai communication.

scientific article published on 28 January 2016

Orai1 and Orai2 mediate store-operated calcium entry that regulates HL60 cell migration and FAK phosphorylation.

scientific article published on 16 November 2016

Pharmacology of TRP channels in the vasculature

scientific article published on 01 July 2013

Phosphatidylinositol 4,5-bisphosphate enhances store-operated calcium entry through hTRPC6 channel in human platelets

scientific article published on 29 July 2007

Physical properties of two types of calcium stores and SERCAs in human platelets.

scientific article

Regulation of Platelet Function by Orai, STIM and TRP.

scientific article published on January 2016

Regulators of G-protein-signaling proteins: negative modulators of G-protein-coupled receptor signaling

scientific article published on 05 March 2015

Role of STIM2 in cell function and physiopathology.

scientific article published on 14 January 2017

Role of oxidant scavengers in the prevention of Ca²+ homeostasis disorders.

scientific article published on 15 October 2010

STIM and Orai1 Variants in Store-Operated Calcium Entry

scientific article

STIM and calcium channel complexes in cancer.

scientific article published on 08 October 2015

STIM1 phosphorylation at Y316 modulates its interaction with SARAF and the activation of SOCE and I CRAC

scientific article published on 15 May 2019

STIM1 tyrosine-phosphorylation is required for STIM1-Orai1 association in human platelets

scientific article published on 25 February 2012

Store-Operated Ca Entry in Breast Cancer Cells: Remodeling and Functional Role ⬇️

scientific article published on 14 December 2018

Store-independent Orai1-mediated Ca2+ entry and cancer

scientific article published on 07 March 2019

Store-operated Ca2+ entry is sensitive to the extracellular Ca2+ concentration through plasma membrane STIM1.

scientific article published on 23 July 2009

TRPC6 Channels Are Required for Proliferation, Migration and Invasion of Breast Cancer Cell Lines by Modulation of Orai1 and Orai3 Surface Exposure

scientific article published on 14 September 2018

TRPs in Pain Sensation

scientific article

The STIM1/Orai signaling machinery

scientific article

The STIM1: Orai Interaction

scientific article published on January 2016

The TRPC ion channels: association with Orai1 and STIM1 proteins and participation in capacitative and non-capacitative calcium entry.

scientific article published on January 2011

The TRPV1 ion channel is expressed in human but not mouse platelets.

scientific article

Transient receptor potential channels in human platelets: expression and functional role.

scientific article published on December 2012

Vaccination prepartum enhances the beneficial effects of melatonin on the immune response and reduces platelet responsiveness in sheep ⬇️

scientific article published on June 20, 2012

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