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List of works by Ren Xu

A novel function of membrane-associated collagen in cancer metastasis

scientific article published on 05 April 2019

Cell shape regulates global histone acetylation in human mammary epithelial cells

scientific article

Chaperone Hsp47 Drives Malignant Growth and Invasion by Modulating an ECM Gene Network

scientific article

Collagen prolyl 4-hydroxylase 1 is essential for HIF-1α stabilization and TNBC chemoresistance

scientific article published in Nature Communications

Delivery of Anti-miRNA for Triple-Negative Breast Cancer Therapy Using RNA Nanoparticles Targeting Stem Cell Marker CD133

scientific article published on 25 April 2019

Depletion of nuclear actin is a key mediator of quiescence in epithelial cells

scientific article

Develop a High-Throughput Screening Method to Identify C-P4H1 (Collagen Prolyl 4-Hydroxylase 1) Inhibitors from FDA-Approved Chemicals

scientific article published on 10 September 2020

Extracellular matrix, nuclear and chromatin structure, and gene expression in normal tissues and malignant tumors: a work in progress.

scientific article

Extracellular matrix-regulated gene expression requires cooperation of SWI/SNF and transcription factors

scientific article

FAM83A confers EGFR-TKI resistance in breast cancer cells and in mice

scientific article

Gene expression in the third dimension: the ECM-nucleus connection

scientific article

Gene transcriptional networks integrate microenvironmental signals in human breast cancer

scientific article

Heat shock protein 47 (HSP47) binds to discoidin domain-containing receptor 2 (DDR2) and regulates its protein stability

scientific article published on 30 September 2019

Hsp47 promotes cancer metastasis by enhancing collagen-dependent cancer cell-platelet interaction

scientific article published on 03 February 2020

Human Cancer and Platelet Interaction, a Potential Therapeutic Target.

scientific article published on 20 April 2018

Increased ROS production in non-polarized mammary epithelial cells induces monocyte infiltration in 3D culture.

scientific article published on 21 September 2016

Integrated extracellular matrix signaling in mammary gland development and breast cancer progression.

scientific article

Krüppel-like factor 4 regulates intestinal epithelial cell morphology and polarity

scientific article

Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia

scientific article published on 09 October 2008

Laminin regulates PI3K basal localization and activation to sustain STAT5 activation.

scientific article

Localization of plasma membrane and secretory calcium pumps in the mammary gland.

scientific article published on 10 March 2008

MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits

scientific article

Membrane associated collagen XIII promotes cancer metastasis and enhances anoikis resistance

scientific article published on 01 October 2018

NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals

scientific article

P4HA1 is a new regulator of the HIF-1 pathway in breast cancer

scientific article published on 09 January 2019

Photonic gene circuits by optically addressable siRNA-Au nanoantennas

scientific article

Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition

scientific article

RORα binds to E2F1 to inhibit cell proliferation and regulate mammary gland branching morphogenesis

scientific article

RORα suppresses breast tumor invasion by inducing SEMA3F expression

scientific article

RORα, a potential tumor suppressor and therapeutic target of breast cancer

scientific article published on 26 November 2012

Roles of PLODs in Collagen Synthesis and Cancer Progression.

scientific article published on 28 June 2018

Sustained activation of STAT5 is essential for chromatin remodeling and maintenance of mammary-specific function.

scientific article published on January 2009

The tumor microenvironment modulates tamoxifen resistance in breast cancer: a role for soluble stromal factors and fibronectin through β1 integrin

scientific article published on 21 September 2011

Tissue architecture and function: dynamic reciprocity via extra- and intra-cellular matrices

scientific article published on June 2009

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