List of works - Miquel Mulero

ANTI-INFLAMMATORY AND PRO-APOPTOTIC PROPERTIES OF THE NATURAL COMPOUND O-ORSELLINALDEHYDE

scientific article published on 11 October 2018

Activity and selectivity cliffs for DPP-IV inhibitors: Lessons we can learn from SAR studies and their application to virtual screening

scientific article published on 16 April 2018

Acute administration of grape seed proanthocyanidin extract modulates energetic metabolism in skeletal muscle and BAT mitochondria

scientific article published on 14 March 2011

Analysis of RXR/THR and RXR/PPARG2 heterodimerization by bioluminescence resonance energy transfer (BRET)

scientific article (publication date: 2013)

Cardioprotective Properties of Phenolic Compounds: A Role for Biological Rhythms

scientific article published in 2022

Characterization of the activity and stability of amylase from saliva and detergent: laboratory practicals for studying the activity and stability of amylase from saliva and various commercial detergents

scientific article published on 18 June 2012

Characterization of the protease activity of detergents: laboratory practicals for studying the protease profile and activity of various commercial detergents

scientific article published on 01 July 2011

Chrononutrition and Polyphenols: Roles and Diseases

scientific article published on 30 October 2019

Combination of grape seed proanthocyanidin extract and docosahexaenoic acid-rich oil increases the hepatic detoxification by GST mediated GSH conjugation in a lipidic postprandial state

scientific article published on 27 May 2014

Combined Ligand- and Receptor-Based Virtual Screening Methodology to Identify Structurally Diverse Protein Tyrosine Phosphatase 1B Inhibitors

scientific article published on 23 August 2018

DHA sensitizes FaO cells to tert-BHP-induced oxidative effects. Protective role of EGCG.

scientific article published on 16 October 2013

DecoyFinder: an easy-to-use python GUI application for building target-specific decoy sets.

scientific article

Development of docking-based 3D-QSAR models for PPARgamma full agonists

scientific article published on 14 March 2012

Ephedrine as a lead compound for the development of new DPP-IV inhibitors.

scientific article

Evaluation of oxidative stress biomarkers in patients with chronic renal failure: a case control study.

scientific article

Gestational exposure to BDE-99 produces toxicity through upregulation of CYP isoforms and ROS production in the fetal rat liver.

scientific article published on 13 February 2012

Granulocyte macrophage--colony-stimulating factor-dependent proliferation is impaired in macrophages from senescence-accelerated mice.

scientific article

Grape seed proanthocyanidin extract improves the hepatic glutathione metabolism in obese Zucker rats

scientific article published on 16 December 2013

Identification of PPARgamma partial agonists of natural origin (I): development of a virtual screening procedure and in vitro validation

scientific article

Identification of human IKK-2 inhibitors of natural origin (Part II): in Silico prediction of IKK-2 inhibitors in natural extracts with known anti-inflammatory activity

scientific article published on 22 September 2011

Identification of human IKK-2 inhibitors of natural origin (part I): modeling of the IKK-2 kinase domain, virtual screening and activity assays

scientific article

Identification of novel human dipeptidyl peptidase-IV inhibitors of natural origin (Part II): in silico prediction in antidiabetic extracts

scientific article

Identification of novel human dipeptidyl peptidase-IV inhibitors of natural origin (part I): virtual screening and activity assays

scientific article

Melatonin reduces oxidative stress in erythrocytes and plasma of senescence-accelerated mice

scientific article published on 01 September 2006

Mining large databases to find new leads with low similarity to known actives: application to find new DPP-IV inhibitors

scientific article published on 01 June 2019

Molecular fingerprint similarity search in virtual screening

scientific article

Optimized Extraction by Response Surface Methodology Used for the Characterization and Quantification of Phenolic Compounds in Whole Red Grapes ()

scientific article published on 05 December 2018

Oral exposure to silver nanoparticles increases oxidative stress markers in the liver of male rats and deregulates the insulin signalling pathway and p53 and cleaved caspase 3 protein expression

scientific article published on 28 March 2018

Oxidative Stress in Rats is Modulated by Seasonal Consumption of Sweet Cherries from Different Geographical Origins: Local vs. Non-Local

scientific article published on 18 September 2020

Oxidative Stress-Related Markers and Langerhans Cells in a Hairless Rat Model Exposed to UV Radiation

scientific article published on 01 July 2006

Perinatal exposure to BDE-99 causes decreased protein levels of cyclin D1 via GSK3β activation and increased ROS production in rat pup livers.

scientific article published on 11 November 2013

Peroxisome Proliferator-Activated Receptor γ (PPARγ) and Ligand Choreography: Newcomers Take the Stage.

scientific article

Polypodium leucotomos extract inhibits glutathione oxidation and prevents Langerhans cell depletion induced by UVB/UVA radiation in a hairless rat model

scientific article

Proanthocyanidins Restore the Metabolic Diurnal Rhythm of Subcutaneous White Adipose Tissue According to Time-Of-Day Consumption

scientific article published in 2022

Resveratrol Potently Counteracts Quercetin Starvation-Induced Autophagy and Sensitizes HepG2 Cancer Cells to Apoptosis.

scientific article published on 16 January 2018

Resveratrol enhances palmitate-induced ER stress and apoptosis in cancer cells

scientific article

Structural insights for the design of new PPARgamma partial agonists with high binding affinity and low transactivation activity

scientific article published on 21 June 2011

The Light and Dark Sides of Virtual Screening: What Is There to Know? ⬇️

scientific article published on 19 March 2019

Tools for in silico target fishing

scientific article published on 30 September 2014

Understanding the variability of the S1' pocket to improve matrix metalloproteinase inhibitor selectivity profiles

scientific article published on 09 September 2019

List of works by Miquel Mulero

ANTI-INFLAMMATORY AND PRO-APOPTOTIC PROPERTIES OF THE NATURAL COMPOUND O-ORSELLINALDEHYDE

Activity and selectivity cliffs for DPP-IV inhibitors: Lessons we can learn from SAR studies and their application to virtual screening

Acute administration of grape seed proanthocyanidin extract modulates energetic metabolism in skeletal muscle and BAT mitochondria

Analysis of RXR/THR and RXR/PPARG2 heterodimerization by bioluminescence resonance energy transfer (BRET)

Cardioprotective Properties of Phenolic Compounds: A Role for Biological Rhythms

Characterization of the activity and stability of amylase from saliva and detergent: laboratory practicals for studying the activity and stability of amylase from saliva and various commercial detergents

Characterization of the protease activity of detergents: laboratory practicals for studying the protease profile and activity of various commercial detergents

Chrononutrition and Polyphenols: Roles and Diseases

Combination of grape seed proanthocyanidin extract and docosahexaenoic acid-rich oil increases the hepatic detoxification by GST mediated GSH conjugation in a lipidic postprandial state

Combined Ligand- and Receptor-Based Virtual Screening Methodology to Identify Structurally Diverse Protein Tyrosine Phosphatase 1B Inhibitors

DHA sensitizes FaO cells to tert-BHP-induced oxidative effects. Protective role of EGCG.

DecoyFinder: an easy-to-use python GUI application for building target-specific decoy sets.

Development of docking-based 3D-QSAR models for PPARgamma full agonists

Ephedrine as a lead compound for the development of new DPP-IV inhibitors.

Evaluation of oxidative stress biomarkers in patients with chronic renal failure: a case control study.

Gestational exposure to BDE-99 produces toxicity through upregulation of CYP isoforms and ROS production in the fetal rat liver.

Granulocyte macrophage--colony-stimulating factor-dependent proliferation is impaired in macrophages from senescence-accelerated mice.

Grape seed proanthocyanidin extract improves the hepatic glutathione metabolism in obese Zucker rats

Identification of PPARgamma partial agonists of natural origin (I): development of a virtual screening procedure and in vitro validation

Identification of human IKK-2 inhibitors of natural origin (Part II): in Silico prediction of IKK-2 inhibitors in natural extracts with known anti-inflammatory activity

Identification of human IKK-2 inhibitors of natural origin (part I): modeling of the IKK-2 kinase domain, virtual screening and activity assays

Identification of novel human dipeptidyl peptidase-IV inhibitors of natural origin (Part II): in silico prediction in antidiabetic extracts

Identification of novel human dipeptidyl peptidase-IV inhibitors of natural origin (part I): virtual screening and activity assays

Melatonin reduces oxidative stress in erythrocytes and plasma of senescence-accelerated mice

Mining large databases to find new leads with low similarity to known actives: application to find new DPP-IV inhibitors

Molecular fingerprint similarity search in virtual screening

Optimized Extraction by Response Surface Methodology Used for the Characterization and Quantification of Phenolic Compounds in Whole Red Grapes ()

Oral exposure to silver nanoparticles increases oxidative stress markers in the liver of male rats and deregulates the insulin signalling pathway and p53 and cleaved caspase 3 protein expression

Oxidative Stress in Rats is Modulated by Seasonal Consumption of Sweet Cherries from Different Geographical Origins: Local vs. Non-Local

Oxidative Stress-Related Markers and Langerhans Cells in a Hairless Rat Model Exposed to UV Radiation

Perinatal exposure to BDE-99 causes decreased protein levels of cyclin D1 via GSK3β activation and increased ROS production in rat pup livers.

Peroxisome Proliferator-Activated Receptor γ (PPARγ) and Ligand Choreography: Newcomers Take the Stage.

Polypodium leucotomos extract inhibits glutathione oxidation and prevents Langerhans cell depletion induced by UVB/UVA radiation in a hairless rat model

Proanthocyanidins Restore the Metabolic Diurnal Rhythm of Subcutaneous White Adipose Tissue According to Time-Of-Day Consumption

Resveratrol Potently Counteracts Quercetin Starvation-Induced Autophagy and Sensitizes HepG2 Cancer Cells to Apoptosis.

Resveratrol enhances palmitate-induced ER stress and apoptosis in cancer cells

Structural insights for the design of new PPARgamma partial agonists with high binding affinity and low transactivation activity

The Light and Dark Sides of Virtual Screening: What Is There to Know? ⬇️

Tools for in silico target fishing

Understanding the variability of the S1' pocket to improve matrix metalloproteinase inhibitor selectivity profiles