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List of works by Hiroshi Hashimoto

A missense mutation in Rev7 disrupts formation of Polζ, impairing mouse development and repair of genotoxic agent-induced DNA lesions.

scientific article published on 19 December 2013

A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin.

scientific article published on 28 January 2014

Correction to "Water-binding phospholipid nanodomains and phase-separated diacylglycerol nanodomains regulate enzyme reactions in lipid monolayers"

scientific article published on 21 April 2015

Crystal structure of basic 7S globulin, a xyloglucan‐specific endo‐β‐1,4‐glucanase inhibitor protein‐like protein from soybean lacking inhibitory activity against endo‐β‐glucanase ⬇️

scientific article published on April 28, 2011

Crystal structure of zinc-finger domain of Nanos and its functional implications

scientific article

Crystallization and X-ray diffraction analysis of the ternary complex of the C-terminal domain of human REV1 in complex with REV7 bound to a REV3 fragment involved in translesion DNA synthesis.

scientific article published on 27 July 2012

Crystallization and preliminary X-ray crystallographic analyses of EcoO109I and its complex with DNA.

scientific article

Crystallization and preliminary X-ray crystallographic studies of transportin 1 in complex with nucleocytoplasmic shuttling and nuclear localization fragments

scientific article

Crystallographic characterization of the N-terminal domain of a plant NADPH oxidase.

scientific article published on 29 August 2008

Crystallographic study of G178S mutant of human proliferating cell nuclear antigen

scientific article published on 20 August 2008

Crystallographic study of a novel DNA-binding domain of human HLTF involved in the template-switching pathway to avoid the replication arrest caused by DNA damage.

scientific article published on 20 May 2015

Dynamic feature of mitotic arrest deficient 2-like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment-maintaining phosphoprotein (CAMP).

scientific article published on 8 September 2017

En bloc transfer of polyubiquitin chains to PCNA in vitro is mediated by two different human E2-E3 pairs.

scientific article

Enzymatic one-step ring contraction for quinolone biosynthesis

scientific article published in Nature Communications

Expression, purification and crystallization of Swi5 and the Swi5-Sfr1 complex from fission yeast

scientific article published on 31 August 2010

Fission Yeast Swi5-Sfr1 Protein Complex, an Activator of Rad51 Recombinase, Forms an Extremely Elongated Dogleg-shaped Structure ⬇️

scientific article published on October 27, 2011

Functional and Structural Analyses of trans C-Methyltransferase in Fungal Polyketide Biosynthesis

scientific article published on 11 September 2019

Identification of the first small-molecule inhibitor of the REV7 DNA repair protein interaction.

scientific article published on 16 July 2016

Inactive dimeric structure of the protease domain of stomatin operon partner protein

scientific article published on 29 May 2020

Mechanistic Insights into the Activation of Rad51-Mediated Strand Exchange from the Structure of a Recombination Activator, the Swi5-Sfr1 Complex ⬇️

scientific article published on March 7, 2012

Mutational effects on O(6)-methylguanine-DNA methyltransferase from hyperthermophile: contribution of ion-pair network to protein thermostability.

scientific article published in April 2004

Oxidative trans to cis Isomerization of Olefins in Polyketide Biosynthesis.

scientific article published on 13 April 2016

Propolis Components from Stingless Bees Collected on South Sulawesi, Indonesia, and Their Xanthine Oxidase Inhibitory Activity

scientific article published on 05 February 2019

Purification, crystallization and X-ray diffraction study of extracellular dermal glycoprotein from carrot and the inhibition complex that it forms with an endo-β-glucanase from Aspergillus aculeatus ⬇️

scientific article published on June 30, 2011

Purification, crystallization and initial X-ray diffraction study of the zinc-finger domain of zebrafish Nanos.

scientific article published on 26 August 2009

Regulation of HLTF-mediated PCNA polyubiquitination by RFC and PCNA monoubiquitination levels determines choice of damage tolerance pathway

scientific article published on 01 November 2018

Structural Basis for Inhibition of Xyloglucan-specific Endo- -1,4-glucanase (XEG) by XEG-Protein Inhibitor

scientific article

Structural Basis for Matrix Metalloproteinase-2 (MMP-2)-selective Inhibitory Action of  -Amyloid Precursor Protein-derived Inhibitor

scientific article

Structural Basis of Recruitment of DNA Polymerase   by Interaction between REV1 and REV7 Proteins

scientific article

Structural Mechanism for Coordination of Proofreading and Polymerase Activities in Archaeal DNA Polymerases

scientific article published on 01 August 2005

Structural and Thermodynamic Basis of the Enhanced Interaction between Kinesin Spindle Protein Eg5 and STLC-type Inhibitors

scientific article published on 28 September 2018

Structural basis for Ca(2+)-induced activation of human PAD4

scientific article

Structural basis for substrate recognition and dissociation by human transportin 1

scientific article

Structural basis for the molecular interactions in DNA damage tolerances

scientific article published on 22 December 2017

Structural basis of HEAT-kleisin interactions in the human condensin I subcomplex

scientific article published on 11 March 2019

Structural basis of autoinhibition and activation of the DNA-targeting ADP-ribosyltransferase pierisin-1.

scientific article published on August 2017

Structural basis of new allosteric inhibition in Kinesin spindle protein Eg5

scientific article

Structure and functional characterization of Vibrio parahaemolyticus thermostable direct hemolysin

scientific article

Structure of HIRAN domain of human HLTF bound to duplex DNA provides structural basis for DNA unwinding to initiate replication fork regression

scientific article published on 21 January 2020

Structure of a Novel DNA-binding Domain of Helicase-like Transcription Factor (HLTF) and Its Functional Implication in DNA Damage Tolerance

scientific article

Structure of proliferating cell nuclear antigen (PCNA) bound to an APIM peptide reveals the universality of PCNA interaction

scientific article published on 22 March 2018

Structure of the HLTF HIRAN domain and its functional implications in regression of a stalled replication fork

scientific article published on 27 July 2020

Structure of the N-terminal Regulatory Domain of a Plant NADPH Oxidase and Its Functional Implications

scientific article

Structure of the RAD9-RAD1-HUS1 checkpoint clamp bound to RHINO sheds light on the other side of the DNA clamp

scientific article published on 27 November 2019

The crystal structure of plant-specific calcium-binding protein AtCBL2 in complex with the regulatory domain of AtCIPK14

scientific article

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