Search filters

List of works by Benjamin Dehay

Acidic nanoparticles protect against α‐synuclein‐induced neurodegeneration through the restoration of lysosomal function

scientific article published on 23 March 2022

Age-dependent α-synuclein aggregation in the Microcebus murinus lemur primate

scientific article

Alpha-synuclein spreading in Parkinson's disease

scientific article

Alpha-synuclein-based models of Parkinson's disease

scientific article published on 2016

Autophagy and brain: the case of neurodegenerative diseases

scientific article published in March 2017

Autophagy in Synucleinopathy: The Overwhelmed and Defective Machinery

scientific article published on 09 June 2019

BAX channel activity mediates lysosomal disruption linked to Parkinson disease.

scientific article published on 26 March 2014

CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease

scientific article published on 28 September 2020

Critical role of the proline-rich region in Huntingtin for aggregation and cytotoxicity in yeast.

scientific article published on 14 September 2006

Down-regulating α-synuclein for treating synucleopathies

scientific article

Efficient generation of A9 midbrain dopaminergic neurons by lentiviral delivery of LMX1A in human embryonic stem cells and induced pluripotent stem cells

scientific article published on 17 November 2011

Endosulfine-alpha inhibits membrane-induced α-synuclein aggregation and protects against α-synuclein neurotoxicity

scientific article published on 10 January 2017

Evidence for the spread of human-derived mutant huntingtin protein in mice and non-human primates

scientific article published on 11 May 2020

Evidence piles Up for prion-like propagation mechanisms in synucleinopathies.

scientific article published on 2 January 2014

Exosomes, an Unmasked Culprit in Neurodegenerative Diseases.

scientific article published on 31 January 2017

Glucocerebrosidase deficiency in dopaminergic neurons induces microglial activation without neurodegeneration.

scientific article published on 17 May 2017

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Harnessing Lysosomal pH through PLGA Nanoemulsion as a Treatment of Lysosomal-Related Neurodegenerative Diseases

scientific article published on 27 November 2018

Harnessing the trophic and modulatory potential of statins in a dopaminergic cell line

scientific article published on 22 December 2015

Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates

scientific article published on 13 May 2020

In utero delivery of rAAV2/9 induces neuronal expression of the transgene in the brain: towards new models of Parkinson's disease.

scientific article published on 30 August 2017

In vitro α-synuclein neurotoxicity and spreading among neurons and astrocytes using Lewy body extracts from Parkinson disease brains.

scientific article published on 11 April 2017

In vivo models of alpha-synuclein transmission and propagation.

scientific article

Intrastriatal injection of alpha-synuclein fibrils induces Parkinson-like pathology in macaques

scientific article published on 01 November 2019

L-DOPA Impairs Proteasome Activity in Parkinsonism through D1 Dopamine Receptor

scientific article published on 01 January 2012

Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression.

scientific article

Lack of spontaneous age-related brain pathology in Octodon degus: a reappraisal of the model

scientific article published on 04 April 2017

Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys.

scientific article published on 18 February 2014

Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration.

scientific article

Lysosomal membrane permeabilization in Parkinson disease

scientific article published on 01 January 2011

Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death.

scientific article

Mapping of the epitope of monoclonal antibody 2B4 to the proline-rich region of human Huntingtin, a region critical for aggregation and toxicity.

scientific article

Multiple System Atrophy: Recent Developments and Future Perspectives

scientific article published on 06 November 2019

Multiple system atrophy: a prototypical synucleinopathy for disease-modifying therapeutic strategies.

scientific article published on 12 April 2014

Nanoparticles restore lysosomal acidification defects: Implications for Parkinson and other lysosomal-related diseases

scientific article published on 13 January 2016

New animal models of Parkinson's disease ⬇️

scientific article published on June 1, 2011

New experimental approach for modeling Parkinson's disease ⬇️

scientific article published on 01 March 2012

Nilotinib Fails to Prevent Synucleinopathy and Cell Loss in a Mouse Model of Multiple System Atrophy

scientific article published on 14 April 2020

Optic atrophy 1 mediates mitochondria remodeling and dopaminergic neurodegeneration linked to complex I deficiency.

scientific article

Pathogenic lysosomal depletion in Parkinson's disease

scientific article published on September 2010

Protein aggregation and neurodegeneration in prototypical neurodegenerative diseases: Examples of amyloidopathies, tauopathies and synucleinopathies

scientific article published on 21 July 2015

RGS9-2 rescues dopamine D2 receptor levels and signaling in dystonia mouse models

scientific article published on 01 January 2019

Reduced oligodendrocyte exosome secretion in multiple system atrophy involves SNARE dysfunction

scientific article published on 18 May 2020

Selective Inactivation of Striatal FosB/ΔFosB-Expressing Neurons Alleviates L-DOPA-Induced Dyskinesia.

scientific article published on 15 July 2014

Single‐molecule approach to find out toxic oligomeric alpa‐synuclein species formation ⬇️

scientific article published on 01 October 2012

Synaptic regulator α-synuclein in dopaminergic fibers is essentially required for the maintenance of subependymal neural stem cells.

scientific article published on 6 December 2017

Synthesis and Intracellular Uptake of Rhodamine-Nucleolipid Conjugates into a Nanoemulsion Vehicle

scientific article published on 12 March 2020

Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling

scientific article published on 10 July 2020

Systemic Gene Delivery by Single-Dose Intracardiac Administration of scAAV2/9 and scAAV2/rh10 Variants in Newborn Rats

article

Systemic gene delivery to the central nervous system using Adeno-associated virus

scientific article

Systemic scAAV9 variant mediates brain transduction in newborn rhesus macaques.

scientific article published on 9 February 2012

Targeting expression of expanded polyglutamine proteins to the endoplasmic reticulum or mitochondria prevents their aggregation.

scholarly article

Targeting α-synuclein for PD Therapeutics: A Pursuit on All Fronts

scientific article published on 03 March 2020

Targeting α-synuclein: Therapeutic options

scientific article published on March 2016

The true nature of α‐synuclein unmasked! ⬇️

scientific article published on 01 November 2011

Transcription factor EB overexpression prevents neurodegeneration in experimental synucleinopathies

scientific article published on 22 August 2019

U18666A, an activator of sterol regulatory element binding protein pathway, modulates presynaptic dopaminergic phenotype of SH-SY5Y neuroblastoma cells

scientific article published on 13 April 2017

Use of adeno-associated virus-mediated delivery of mutant huntingtin to study the spreading capacity of the protein in mice and non-human primates

scientific article published on 18 May 2020

What lysosomes actually tell us about Parkinson's disease?

scientific article published on 3 March 2016

α-synuclein, a prion-like protein

scientific article published on 01 April 2011

Paulina is supported by:

About Paulina

Help