List of works - D R Mani

A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease.

scientific article

Automated Microchromatography Enables Multiplexing of Immunoaffinity Enrichment of Peptides to Greater than 150 for Targeted MS-Based Assays.

scientific article published on 18 June 2016

Automated detection of inaccurate and imprecise transitions in peptide quantification by multiple reaction monitoring mass spectrometry.

scientific article

Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy

scientific article

Clustering with position-specific constraints on variance: Applying redescending M-estimators to label-free LC-MS data analysis ⬇️

scientific article published on August 31, 2011

Identification of apolipoprotein D as a cardioprotective gene using a mouse model of lethal atherosclerotic coronary artery disease

scientific article published on 30 September 2013

Integrated proteomic analysis of post-translational modifications by serial enrichment.

scientific article published on 09 June 2013

Interlaboratory evaluation of automated, multiplexed peptide immunoaffinity enrichment coupled to multiple reaction monitoring mass spectrometry for quantifying proteins in plasma

scientific article

Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels

scientific article

Large-Scale Interlaboratory Study to Develop, Analytically Validate and Apply Highly Multiplexed, Quantitative Peptide Assays to Measure Cancer-Relevant Proteins in Plasma.

scientific article

Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS.

scientific article

Mass spectrometry-based proteomics reveals potential roles of NEK9 and MAP2K4 in resistance to PI3K inhibitors in triple negative breast cancers.

scientific article published on 22 February 2018

Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. ⬇️

scientific article

Methods, Tools and Current Perspectives in Proteogenomics

scientific article published on 29 April 2017

Multiplexed, Quantitative Workflow for Sensitive Biomarker Discovery in Plasma Yields Novel Candidates for Early Myocardial Injury.

scientific article

PANOPLY: a cloud-based platform for automated and reproducible proteogenomic data analysis

scientific article published on 26 May 2021

PEPPeR, a platform for experimental proteomic pattern recognition.

scientific article published on 19 July 2006

Proteogenomic integration reveals therapeutic targets in breast cancer xenografts

scientific article published on 28 March 2017

Quantification of cardiovascular biomarkers in patient plasma by targeted mass spectrometry and stable isotope dilution.

scientific article published on 13 July 2009

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

scientific article published on 10 January 2017

Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.

scientific article published on 24 December 2012

Simplified and efficient quantification of low-abundance proteins at very high multiplex via targeted mass spectrometry

scientific article published on 11 February 2014

Statistical characterization of multiple-reaction monitoring mass spectrometry (MRM-MS) assays for quantitative proteomics ⬇️

scientific article published on November 5, 2012

Targeted peptide measurements in biology and medicine: best practices for mass spectrometry-based assay development using a fit-for-purpose approach

scientific article published on 17 January 2014

Transitioning from Targeted to Comprehensive Mass Spectrometry Using Genetic Algorithms.

scientific article

Using the CPTAC Assay Portal to Identify and Implement Highly Characterized Targeted Proteomics Assays

scientific article published on January 2016

List of works by D R Mani

A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease.

Automated Microchromatography Enables Multiplexing of Immunoaffinity Enrichment of Peptides to Greater than 150 for Targeted MS-Based Assays.

Automated detection of inaccurate and imprecise transitions in peptide quantification by multiple reaction monitoring mass spectrometry.

Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy

Clustering with position-specific constraints on variance: Applying redescending M-estimators to label-free LC-MS data analysis ⬇️

Identification of apolipoprotein D as a cardioprotective gene using a mouse model of lethal atherosclerotic coronary artery disease

Integrated proteomic analysis of post-translational modifications by serial enrichment.

Interlaboratory evaluation of automated, multiplexed peptide immunoaffinity enrichment coupled to multiple reaction monitoring mass spectrometry for quantifying proteins in plasma

Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels

Large-Scale Interlaboratory Study to Develop, Analytically Validate and Apply Highly Multiplexed, Quantitative Peptide Assays to Measure Cancer-Relevant Proteins in Plasma.

Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS.

Mass spectrometry-based proteomics reveals potential roles of NEK9 and MAP2K4 in resistance to PI3K inhibitors in triple negative breast cancers.

Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. ⬇️

Methods, Tools and Current Perspectives in Proteogenomics

Multiplexed, Quantitative Workflow for Sensitive Biomarker Discovery in Plasma Yields Novel Candidates for Early Myocardial Injury.

PANOPLY: a cloud-based platform for automated and reproducible proteogenomic data analysis

PEPPeR, a platform for experimental proteomic pattern recognition.

Proteogenomic integration reveals therapeutic targets in breast cancer xenografts

Quantification of cardiovascular biomarkers in patient plasma by targeted mass spectrometry and stable isotope dilution.

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.

Simplified and efficient quantification of low-abundance proteins at very high multiplex via targeted mass spectrometry

Statistical characterization of multiple-reaction monitoring mass spectrometry (MRM-MS) assays for quantitative proteomics ⬇️

Targeted peptide measurements in biology and medicine: best practices for mass spectrometry-based assay development using a fit-for-purpose approach

Transitioning from Targeted to Comprehensive Mass Spectrometry Using Genetic Algorithms.

Using the CPTAC Assay Portal to Identify and Implement Highly Characterized Targeted Proteomics Assays