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List of works by Chris Benner

53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration.

scientific article

A longitudinal systems immunologic investigation of acute Zika virus infection in an individual infected while traveling to Caracas, Venezuela

article

ARTDeco: automatic readthrough transcription detection

scientific article published on 26 May 2020

An alternative pluripotent state confers interspecies chimaeric competency

scientific article

An evolutionarily conserved DNA architecture determines target specificity of the TWIST family bHLH transcription factors.

scientific article

ApoC-III ASO promotes tissue LPL activity in the absence of apoE-mediated TRL clearance

scientific article published on 14 May 2019

Author Correction: Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity

scientific article published in Nature

BRD4 is a novel therapeutic target for liver fibrosis

scientific article

Bcl-6 and NF-kappaB cistromes mediate opposing regulation of the innate immune response.

scientific article published on 24 November 2010

Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers

scientific article published on 2 October 2017

Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome

scientific article published on 06 March 2019

Combining TSS-MPRA and sensitive TSS profile dissimilarity scoring to study the sequence determinants of transcription initiation

scientific article published on 5 July 2023

Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization

scientific article

Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways

scientific journal article

Decoding Transcription Regulatory Mechanisms Associated with <i>Coccidioides immitis</i> Phase Transition Using Total RNA

scientific article published on 25 January 2022

Decoding a signature-based model of transcription cofactor recruitment dictated by cardinal cis-regulatory elements in proximal promoter regions.

scientific article published on 7 November 2013

Deconvolution of pro- and antiviral genomic responses in Zika virus-infected and bystander macrophages

article published in the Proceedings of the National Academy of Sciences of the United States of America

Differential L1 regulation in pluripotent stem cells of humans and apes.

scientific article published on 23 October 2013

Diverse motif ensembles specify non-redundant DNA binding activities of AP-1 family members in macrophages

scientific article published in Nature Communications

Dynamic epigenetic enhancer signatures reveal key transcription factors associated with monocytic differentiation states.

scientific article published in May 2012

Effect of natural genetic variation on enhancer selection and function.

scientific article published on 13 October 2013

Emergence of a Homo sapiens-specific gene family and chromosome 16p11.2 CNV susceptibility

scientific article published on 03 August 2016

Evolution of a transcriptional regulator from a transmembrane nucleoporin

scientific article published on 19 May 2016

Function of a Foxp3 cis-element in protecting regulatory T cell identity

scientific article

Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes

scientific article published on 27 August 2013

Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer.

scientific article published on 31 May 2018

Human-gained heart enhancers are associated with species-specific cardiac attributes

scientific article published in 2022

Identification and dynamic quantification of regulatory elements using total RNA

scientific article published on 24 October 2019

Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development.

scientific article published on 4 March 2015

In silico discovery of transcription regulatory elements in Plasmodium falciparum.

scientific article

Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity

scientific article

Influenza virus repurposes the antiviral protein IFIT2 to promote translation of viral mRNAs

scientific article published on 24 August 2020

LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development

scientific article published on 29 April 2020

Leveraging two-way probe-level block design for identifying differential gene expression with high-density oligonucleotide arrays

scientific article

MEIRLOP: improving score-based motif enrichment by incorporating sequence bias covariates

scientific article published on 16 September 2020

MHC class II proteins mediate cross-species entry of bat influenza viruses

scientific article published in Nature

Massively Parallel Sequencing of Peritoneal and Splenic B Cell Repertoires Highlights Unique Properties of B-1 Cell Antibodies

scientific article

Mechanisms establishing TLR4-responsive activation states of inflammatory response genes.

scientific article

Mechanisms of in vivo binding site selection of the hematopoietic master transcription factor PU.1.

scientific article published on 8 May 2013

Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis.

scientific article published on 13 March 2017

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

scientific article published on 03 April 2019

Molecular determinants of crosstalk between nuclear receptors and toll-like receptors.

scientific article published on September 2005

Multilineage priming of enhancer repertoires precedes commitment to the B and myeloid cell lineages in hematopoietic progenitors.

scientific article published on 08 September 2011

Mutant p53 shapes the enhancer landscape of cancer cells in response to chronic immune signaling.

scientific article published on 29 September 2017

Mutations in foregut SOX2+ cells induce efficient proliferation via CXCR2 pathway

scientific article published on 30 April 2019

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

scientific article

Nascent RNA sequencing reveals distinct features in plant transcription

scientific article published on 11 October 2016

New roles for DNA cytosine modification, eRNA, anchors, and superanchors in developing B cell progenitors

scientific article

Nucleoporin-mediated regulation of cell identity genes.

scientific article

Nup98 recruits the Wdr82-Set1A/COMPASS complex to promoters to regulate H3K4 trimethylation in hematopoietic progenitor cells.

scientific article published on 21 December 2017

Paradoxical association of TET loss of function with genome-wide DNA hypomethylation

scientific article published on 01 August 2019

Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate

scientific article

Presenilins regulate neurotrypsin gene expression and neurotrypsin-dependent agrin cleavage via cyclic AMP response element-binding protein (CREB) modulation

scientific article published on 21 October 2013

Primate-specific ORF0 contributes to retrotransposon-mediated diversity

scientific article

Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN.

scientific article published in September 2017

Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.

scientific article published on August 2013

Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA

2011 thesis

Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy

scientific article published on 23 September 2021

Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription.

scientific article published on 02 June 2013

SMADs and YAP compete to control elongation of β-catenin:LEF-1-recruited RNAPII during hESC differentiation.

scientific article published on 30 April 2015

Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis

scientific article

Sensitive ChIP-DSL technology reveals an extensive estrogen receptor alpha-binding program on human gene promoters.

scholarly article

Systems biology of macrophages.

scientific article published on January 2007

Targeted gene correction minimally impacts whole-genome mutational load in human-disease-specific induced pluripotent stem cell clones.

scientific article

Targeting the spliceosome in chronic lymphocytic leukemia with the macrolides FD-895 and pladienolide-B.

scientific article published on 10 April 2015

The DAXX co-repressor is directly recruited to active regulatory elements genome-wide to regulate autophagy programs in a model of human prostate cancer.

scientific article published on 17 April 2015

The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene silencing

scientific article published on 16 June 2015

The selection and function of cell type-specific enhancers

scientific article

The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression.

scientific article

Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation.

scientific article

Transcription Elongation Can Affect Genome 3D Structure

scientific article published on 23 August 2018

Transcriptional effects of colony-stimulating factor-1 in mouse macrophages

scientific article published on 15 September 2009

Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing

scientific article published on 25 June 2022

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