List of works - Virginia Haurigot

AAV-mediated pancreatic overexpression of Igf1 counteracts progression to autoimmune diabetes in mice.

scientific article

Biochemical, histological and functional correction of mucopolysaccharidosis type IIIB by intra-cerebrospinal fluid gene therapy

scientific article published on 18 December 2014

CNS-directed gene therapy for the treatment of neurologic and somatic mucopolysaccharidosis type II (Hunter syndrome)

scientific article

Disease correction by AAV-mediated gene therapy in a new mouse model of mucopolysaccharidosis type IIID.

scientific article published on 17 February 2017

IGF-I mediates regeneration of endocrine pancreas by increasing beta cell replication through cell cycle protein modulation in mice.

scientific article

In vivo gene transfer to pancreatic beta cells by systemic delivery of adenoviral vectors.

scientific article published in August 2004

In vivo genome editing restores haemostasis in a mouse model of haemophilia

scientific article (publication date: 26 June 2011)

Increased ocular levels of IGF-1 in transgenic mice lead to diabetes-like eye disease.

scientific article published on April 2004

Inhibition of hepatitis C virus replication using adeno-associated virus vector delivery of an exogenous anti-hepatitis C virus microRNA cluster.

scientific article published on 7 October 2010

Insulin-like Growth Factor 2 Overexpression Induces β-Cell Dysfunction and Increases Beta-cell Susceptibility to Damage

scientific article published on 13 May 2015

Insulin-like growth factor I (IGF-I)-induced chronic gliosis and retinal stress lead to neurodegeneration in a mouse model of retinopathy

scientific article published on 25 April 2013

Long-Term Efficacy and Safety of Insulin and Glucokinase Gene Therapy for Diabetes: 8-Year Follow-Up in Dogs

scientific article published on 5 April 2017

Long-Term Retinal PEDF Overexpression Prevents Neovascularization in a Murine Adult Model of Retinopathy ⬇️

scientific article published on July 20, 2012

Modulation of CD8+ T cell responses to AAV vectors with IgG-derived MHC class II epitopes

scientific article published on 16 July 2013

Peripheral transvenular delivery of adeno-associated viral vectors to skeletal muscle as a novel therapy for hemophilia B.

scientific article

Progressive neurologic and somatic disease in a novel mouse model of human mucopolysaccharidosis type IIIC.

scientific article published on 04 August 2016

Proliferative retinopathies: animal models and therapeutic opportunities

scientific article

Robust ZFN-mediated genome editing in adult hemophilic mice.

scientific article published on October 2013

Safety of AAV factor IX peripheral transvenular gene delivery to muscle in hemophilia B dogs.

scientific article

Toward a gene therapy for neurological and somatic MPSIIIA

scientific article published on 12 December 2013

Treatment of diabetes and long-term survival after insulin and glucokinase gene therapy.

scientific article

Whole body correction of mucopolysaccharidosis IIIA by intracerebrospinal fluid gene therapy

scientific article

List of works by Virginia Haurigot

AAV-mediated pancreatic overexpression of Igf1 counteracts progression to autoimmune diabetes in mice.

Biochemical, histological and functional correction of mucopolysaccharidosis type IIIB by intra-cerebrospinal fluid gene therapy

CNS-directed gene therapy for the treatment of neurologic and somatic mucopolysaccharidosis type II (Hunter syndrome)

Disease correction by AAV-mediated gene therapy in a new mouse model of mucopolysaccharidosis type IIID.

IGF-I mediates regeneration of endocrine pancreas by increasing beta cell replication through cell cycle protein modulation in mice.

In vivo gene transfer to pancreatic beta cells by systemic delivery of adenoviral vectors.

In vivo genome editing restores haemostasis in a mouse model of haemophilia

Increased ocular levels of IGF-1 in transgenic mice lead to diabetes-like eye disease.

Inhibition of hepatitis C virus replication using adeno-associated virus vector delivery of an exogenous anti-hepatitis C virus microRNA cluster.

Insulin-like Growth Factor 2 Overexpression Induces β-Cell Dysfunction and Increases Beta-cell Susceptibility to Damage

Insulin-like growth factor I (IGF-I)-induced chronic gliosis and retinal stress lead to neurodegeneration in a mouse model of retinopathy

Long-Term Efficacy and Safety of Insulin and Glucokinase Gene Therapy for Diabetes: 8-Year Follow-Up in Dogs

Long-Term Retinal PEDF Overexpression Prevents Neovascularization in a Murine Adult Model of Retinopathy ⬇️

Modulation of CD8+ T cell responses to AAV vectors with IgG-derived MHC class II epitopes

Peripheral transvenular delivery of adeno-associated viral vectors to skeletal muscle as a novel therapy for hemophilia B.

Progressive neurologic and somatic disease in a novel mouse model of human mucopolysaccharidosis type IIIC.

Proliferative retinopathies: animal models and therapeutic opportunities

Robust ZFN-mediated genome editing in adult hemophilic mice.

Safety of AAV factor IX peripheral transvenular gene delivery to muscle in hemophilia B dogs.

Toward a gene therapy for neurological and somatic MPSIIIA

Treatment of diabetes and long-term survival after insulin and glucokinase gene therapy.

Whole body correction of mucopolysaccharidosis IIIA by intracerebrospinal fluid gene therapy