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List of works by Fernando J Pitossi

A familiar study on self-limited childhood epilepsy patients using hIPSC-derived neurons shows a bias towards immaturity at the morphological, electrophysiological and gene expression levels

scientific article published on 25 November 2021

A neuromodulatory role of interleukin-1β in the hippocampus ⬇️

scientific article published on June 23, 1998

A new focal model resembling features of cortical pathology of the progressive forms of multiple sclerosis: influence of innate immunity

scientific article published on 26 January 2018

CNS response to a second pro-inflammatory event depends on whether the primary demyelinating lesion is active or resolved.

scientific article published on 21 July 2012

Cell reprogramming and neuronal differentiation applied to neurodegenerative diseases: Focus on Parkinson's disease

scientific article

Cell therapy for Parkinson's disease is coming of age: current challenges and future prospects with a focus on immunomodulation

scientific article published on 16 April 2019

Cell therapy for Parkinson's disease: Functional role of the host immune response on survival and differentiation of dopaminergic neuroblasts

scientific article published on 31 July 2015

Chronic Hippocampal Expression of Notch Intracellular Domain Induces Vascular Thickening, Reduces Glucose Availability, and Exacerbates Spatial Memory Deficits in a Rat Model of Early Alzheimer

scientific article published on 26 March 2018

Chronic expression of low levels of tumor necrosis factor-alpha in the substantia nigra elicits progressive neurodegeneration, delayed motor symptoms and microglia/macrophage activation.

scientific article published on 5 December 2009

Chronic systemic IL-1β exacerbates central neuroinflammation independently of the blood-brain barrier integrity

scientific article published on 28 November 2014

Current status of stem cells and regenerative medicine research in Argentina.

scientific article published in December 2014

Differential effects of interleukin-1beta on neurotoxicity, cytokine induction and glial reaction in specific brain regions.

scientific article

Differential vulnerability of adult neurogenesis by adult and prenatal inflammation: Role of TGF-β1 ⬇️

scientific article published on May 31, 2013

Differentiation of mesenchymal stem cells into retinal progenitor cells

scientific article published on 10 December 2014

Early and adult hippocampal TGF-β1 overexpression have opposite effects on behavior.

scientific article published on 24 May 2011

Environmental enrichment improves cognitive symptoms and pathological features in a focal model of cortical damage of multiple sclerosis

scientific article published on 24 October 2019

Fibulin-2 is a key mediator of the pro-neurogenic effect of TGF-beta1 on adult neural stem cells.

scientific article published on 5 June 2015

Glial Cell-Elicited Activation of Brain Microvasculature in Response to Brucella abortus Infection Requires ASC Inflammasome-Dependent IL-1β Production.

scientific article published on 16 March 2016

Interleukin-1β and tumor necrosis factor-α: reliable targets for protective therapies in Parkinson's Disease?

scientific article published on 29 April 2013

Iron Availability Compromises Not Only Oligodendrocytes But Also Astrocytes and Microglial Cells.

scientific article published on 14 January 2017

Learning modulation by endogenous hippocampal IL-1: blockade of endogenous IL-1 facilitates memory formation.

scientific article published in January 2004

Model based analysis of real-time PCR data from DNA binding dye protocols.

scientific article

Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily ⬇️

scientific article published on May 15, 1991

Neuronal differentiation in the adult hippocampus recapitulates embryonic development.

scientific article published in November 2005

Neuroprotective effects of human umbilical cord mesenchymal stromal cells in an immunocompetent animal model of Parkinson's disease ⬇️

scientific article published on March 27, 2012

Nigral neurodegeneration triggered by striatal AdIL-1 administration can be exacerbated by systemic IL-1 expression.

scientific article published on 29 March 2010

Notch signaling proteins HES-1 and Hey-1 bind to insulin degrading enzyme (IDE) proximal promoter and repress its transcription and activity: Implications for cellular Aβ metabolism ⬇️

scientific article published on October 19, 2011

Overexpression of IL-1beta by adenoviral-mediated gene transfer in the rat brain causes a prolonged hepatic chemokine response, axonal injury and the suppression of spontaneous behaviour.

scientific article published on 16 May 2007

Patients Beware: Commercialized Stem Cell Treatments on the Web

scientific article published on 17 June 2010

Pleiotrophin over-expression provides trophic support to dopaminergic neurons in parkinsonian rats ⬇️

scientific article published on June 7, 2011

Prenatal inflammation impairs adult neurogenesis and memory related behavior through persistent hippocampal TGFβ1 downregulation.

scientific article published on 20 June 2010

Progressive neurodegeneration and motor disabilities induced by chronic expression of IL-1beta in the substantia nigra.

scientific article published on 9 August 2006

Reversible demyelination, blood-brain barrier breakdown, and pronounced neutrophil recruitment induced by chronic IL-1 expression in the brain.

scientific article

Secreted protein acidic and rich in cysteine produced by human melanoma cells modulates polymorphonuclear leukocyte recruitment and antitumor cytotoxic capacity.

scientific article published on June 2005

Special issue commentary: the changing face of inflammation in the brain.

scientific article

Stem cell research in Latin America: update, challenges and opportunities in a priority research area

scientific article

Study of cytokine induced neuropathology by high resolution proton NMR spectroscopy of rat urine.

scientific article

The degenerating substantia nigra as a susceptible region for gene transfer-mediated inflammation.

scientific article

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